Christian Diederich, PhD
Professor
Radiation Oncology
School of Medicine

I have authored numerous research publications, covering topics such as motion-robust MR thermometry, ultrasound applicators for therapeutic ultrasound, MR-guided thermal therapy, and ultrasound-based treatment of various malignancies.

My contributions to the field have been recognized with several prestigious awards and honors, including the ESHO - Pyrexar Award from the European Society of Hyperthermic Oncology and being named a Fellow of the American Association of Physicists in Medicine. I have also served as the President of the North American Hyperthermia Society.

Throughout my career, I have been actively involved in leading research projects sponsored by the NIH, focusing on image-guided ultrasound ablation for precision targeting of prostate cancer, deployable ultrasound applicators for MRI-guided thermal therapy of pancreatic cancer, and methods for precise MR-guided hyperthermia delivery for targeted cancer therapies. Additionally, I have undertaken projects involving minimally-invasive catheter-based ultrasound for tumor ablation in the lung and non-thermal pulsed FUS (focused ultrasound) for the treatment of intervertebral disc degeneration.

In summary, my work as a Professor in Radiation Oncology at UCSF centers on advancing the field of thermal therapy, ultrasound-based treatments, and image-guided interventions for cancer and other medical conditions, with a strong emphasis on precision and innovation.

• AAPM Task Group 241: A medical physicist's guide to MRI-guided focused ultrasound body systems.
  Medical physics 2021 Payne A, Chopra R, Ellens N, Chen L, Ghanouni P, Sammet S, Diederich C, Ter Haar G, Parker D, Moonen C, Stafford J, Moros E, Schlesinger D, Benedict S, Wear K, Partanen A, Farahani K
• Anatomic thermochromic tissue-mimicking phantom of the lumbar spine for pre-clinical evaluation of MR-guided focused ultrasound (MRgFUS) ablation of the facet joint.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2021 Zhang W, Trivedi H, Adams M, Losey AD, Diederich CJ, Ozhinsky E, Rieke V, Bucknor MD
• Sonication strategies toward volumetric ultrasound hyperthermia treatment using the ExAblate body MRgFUS system.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2021 Kim K, Zubair M, Adams M, Diederich CJ, Ozhinsky E
• In silico feasibility assessment of extracorporeal delivery of low-intensity pulsed ultrasound to intervertebral discs within the lumbar spine.
  Physics in medicine and biology 2020 Adams MS, Lotz JC, Diederich CJ
• Microbubble-Facilitated Ultrasound Catheter Ablation Causes Microvascular Damage and Fibrosis.
  Ultrasound in medicine & biology 2020 Nazer B, Giraud D, Zhao Y, Qi Y, Mason O, Jones PD, Diederich CJ, Gerstenfeld EP, Lindner JR
• In vivo Nakagami-m parametric imaging of microbubble-enhanced ultrasound regulated by RF and VF processing techniques.
  Medical physics 2020 Wang D, Liu D, Sang Y, Zhang Y, Wan M, Diederich CJ
• LIPUS far-field exposimetry system for uniform stimulation of tissues in-vitro: development and validation with bovine intervertebral disc cells.
  Biomedical physics & engineering express 2020 Horne DA, Jones PD, Adams MS, Lotz JC, Diederich CJ
• Dual-sectored transurethral ultrasound for thermal treatment of stress urinary incontinence: in silico studies in 3D anatomical models.
  Medical & biological engineering & computing 2020 Liu D, Adams M, Burdette EC, Diederich CJ
• Deployable cylindrical phased-array applicator mimicking a concentric-ring configuration for minimally-invasive delivery of therapeutic ultrasound.
  Physics in medicine and biology 2019 Adams MS, Diederich CJ
• Quality assurance guidelines for interstitial hyperthermia.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2019 Dobšícek Trefná H, Schmidt M, van Rhoon GC, Kok HP, Gordeyev SS, Lamprecht U, Marder D, Nadobny J, Ghadjar P, Abdel-Rahman S, Kukielka AM, Strnad V, Hurwitz MD, Vujaskovic Z, Diederich CJ, Stauffer PR…
• Endobronchial high-intensity ultrasound for thermal therapy of pulmonary malignancies: simulations with patient-specific lung models.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2019 Liu D, Adams MS, Diederich CJ
• Noninvasive, Targeted Creation of Neuromyelitis Optica Pathology in AQP4-IgG Seropositive Rats by Pulsed Focused Ultrasound.
  Journal of neuropathology and experimental neurology 2019 Yao X, Adams MS, Jones PD, Diederich CJ, Verkman AS
• 880 kHz ultrasound treatment for drug delivery to the vitreous humor.
  American journal of translational research 2018 Lamy R, Chan E, Lee OT, Phone A, Salgaonkar VA, Diederich CJ, Stewart JM
• MR thermometry-guided ultrasound hyperthermia of user-defined regions using the ExAblate prostate ablation array.
  Journal of therapeutic ultrasound 2018 Ozhinsky E, Salgaonkar VA, Diederich CJ, Rieke V
• Assessing high-intensity focused ultrasound treatment of prostate cancer with hyperpolarized 13 C dual-agent imaging of metabolism and perfusion.
  NMR in biomedicine 2018 Lee JE, Diederich CJ, Bok R, Sriram R, Santos RD, Noworolski SM, Salgaonkar VA, Adams MS, Vigneron DB, Kurhanewicz J
• Transurethral high-intensity ultrasound for treatment of stress urinary incontinence (SUI): simulation studies with patient-specific models.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2018 Liu D, Adams MS, Burdette EC, Diederich CJ
• A minimally invasive catheter-based ultrasound technology for therapeutic interventions in brain: initial preclinical studies.
  Neurosurgical focus 2018 Ghoshal G, Gee L, Heffter T, Williams E, Bromfield C, Rund L, Ehrhardt JM, Diederich CJ, Fischer GS, Pilitsis JG, Burdette EC
• Integration of deployable fluid lenses and reflectors with endoluminal therapeutic ultrasound applicators: Preliminary investigations of enhanced penetration depth and focal gain.
  Medical physics 2017 Adams MS, Salgaonkar VA, Scott SJ, Sommer G, Diederich CJ
• Theoretical investigation of transgastric and intraductal approaches for ultrasound-based thermal therapy of the pancreas.
  Journal of therapeutic ultrasound 2017 Scott SJ, Adams MS, Salgaonkar V, Sommer FG, Diederich CJ
• Quality assurance guidelines for superficial hyperthermia clinical trials : II. Technical requirements for heating devices.
  Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 2017 Dobšícek Trefná H, Crezee J, Schmidt M, Marder D, Lamprecht U, Ehmann M, Nadobny J, Hartmann J, Lomax N, Abdel-Rahman S, Curto S, Bakker A, Hurwitz MD, Diederich CJ, Stauffer PR, Van Rhoon GC
• Low intensity pulsed ultrasound (LIPUS) for the treatment of intervertebral disc degeneration.
  Proceedings of SPIE--the International Society for Optical Engineering 2017 Horne D, Jones P, Salgaonkar V, Adams M, Ozilgen BA, Zahos P, Tang X, Liebenburg E, Coughlin D, Lotz J, Diederich C
• Quality assurance guidelines for superficial hyperthermia clinical trials: I. Clinical requirements.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2017 Trefná HD, Crezee H, Schmidt M, Marder D, Lamprecht U, Ehmann M, Hartmann J, Nadobny J, Gellermann J, van Holthe N, Ghadjar P, Lomax N, Abdel-Rahman S, Bert C, Bakker A, Hurwitz MD, Diederich CJ, …
• Endoluminal ultrasound applicators for MR-guided thermal ablation of pancreatic tumors: Preliminary design and evaluation in a porcine pancreas model.
  Medical physics 2016 Adams MS, Salgaonkar VA, Plata-Camargo J, Jones PD, Pascal-Tenorio A, Chen HY, Bouley DM, Sommer G, Pauly KB, Diederich CJ
• Clinical applications of custom-made vaginal cylinders constructed using three-dimensional printing technology.
  Journal of contemporary brachytherapy 2016 Sethi R, Cunha A, Mellis K, Siauw T, Diederich C, Pouliot J, Hsu IC
• Thermal therapy of pancreatic tumours using endoluminal ultrasound: Parametric and patient-specific modelling.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2016 Adams MS, Scott SJ, Salgaonkar VA, Sommer G, Diederich CJ
• Epicardial Catheter Ablation Using High-Intensity Ultrasound: Validation in a Swine Model.
  Circulation. Arrhythmia and electrophysiology 2015 Nazer B, Salgaonkar V, Diederich CJ, Jones PD, Duggirala S, Tanaka Y, Ng B, Sievers R, Gerstenfeld EP
• Quantifying temperature-dependent T1 changes in cortical bone using ultrashort echo-time MRI.
  Magnetic resonance in medicine 2015 Han M, Rieke V, Scott SJ, Ozhinsky E, Salgaonkar VA, Jones PD, Larson PE, Diederich CJ, Krug R
• A feasibility study on monitoring the evolution of apparent diffusion coefficient decrease during thermal ablation.
  Medical physics 2015 Plata JC, Holbrook AB, Marx M, Salgaonkar V, Jones P, Pascal-Tenorio A, Bouley D, Diederich C, Sommer G, Pauly KB
• Catheter-based ultrasound technology for image-guided thermal therapy: current technology and applications.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2015 Salgaonkar VA, Diederich CJ
• Development of an endoluminal high-intensity ultrasound applicator for image-guided thermal therapy of pancreatic tumors.
  Proceedings of SPIE--the International Society for Optical Engineering 2015 Adams MS, Scott SJ, Salgaonkar VA, Jones PD, Plata-Camargo JC, Sommer G, Diederich CJ
• Two phase I dose-escalation/pharmacokinetics studies of low temperature liposomal doxorubicin (LTLD) and mild local hyperthermia in heavily pretreated patients with local regionally recurrent breast cancer.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2014 Zagar TM, Vujaskovic Z, Formenti S, Rugo H, Muggia F, O'Connor B, Myerson R, Stauffer P, Hsu IC, Diederich C, Straube W, Boss MK, Boico A, Craciunescu O, Maccarini P, Needham D, Borys N, Blackwell KL,…
• Interstitial ultrasound ablation of vertebral and paraspinal tumours: parametric and patient-specific simulations.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2014 Scott SJ, Salgaonkar V, Prakash P, Burdette EC, Diederich CJ
• Model-based feasibility assessment and evaluation of prostate hyperthermia with a commercial MR-guided endorectal HIFU ablation array.
  Medical physics 2014 Salgaonkar VA, Prakash P, Rieke V, Ozhinsky E, Plata J, Kurhanewicz J, Hsu IC, Diederich CJ
• Components of a hyperthermia clinic: recommendations for staffing, equipment, and treatment monitoring.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2013 Myerson RJ, Moros EG, Diederich CJ, Haemmerich D, Hurwitz MD, Hsu IC, McGough RJ, Nau WH, Straube WL, Turner PF, Vujaskovic Z, Stauffer PR
• Approaches for modelling interstitial ultrasound ablation of tumours within or adjacent to bone: theoretical and experimental evaluations.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2013 Scott SJ, Prakash P, Salgaonkar V, Jones PD, Cam RN, Han M, Rieke V, Burdette EC, Diederich CJ
• Ultrasound-enhanced penetration of topical riboflavin into the corneal stroma.
  Investigative ophthalmology & visual science 2013 Lamy R, Chan E, Zhang H, Salgaonkar VA, Good SD, Porco TC, Diederich CJ, Stewart JM
• MR-guided focused ultrasound surgery, present and future.
  Medical physics 2013 Schlesinger D, Benedict S, Diederich C, Gedroyc W, Klibanov A, Larner J
• Applicators for magnetic resonance-guided ultrasonic ablation of benign prostatic hyperplasia.
  Investigative radiology 2013 Sommer G, Pauly KB, Holbrook A, Plata J, Daniel B, Bouley D, Gill H, Prakash P, Salgaonkar V, Jones P, Diederich C
• Modelling of endoluminal and interstitial ultrasound hyperthermia and thermal ablation: applications for device design, feedback control and treatment planning.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2013 Prakash P, Salgaonkar VA, Diederich CJ
• Simulation techniques in hyperthermia treatment planning.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2013 Paulides MM, Stauffer PR, Neufeld E, Maccarini PF, Kyriakou A, Canters RA, Diederich CJ, Bakker JF, Van Rhoon GC
• Focal ablation of prostate cancer: four roles for magnetic resonance imaging guidance.
  The Canadian journal of urology 2013 Sommer G, Bouley D, Gill H, Daniel B, Pauly KB, Diederich C
• MR guided thermal therapy of pancreatic tumors with endoluminal, intraluminal and interstitial catheter-based ultrasound devices: Preliminary theoretical and experimental investigations.
  Proceedings of SPIE--the International Society for Optical Engineering 2013 Prakash P, Salgaonkar VA, Scott SJ, Jones P, Hensley D, Holbrook A, Plata J, Sommer G, Diederich CJ
• Multiple applicator hepatic ablation with interstitial ultrasound devices: theoretical and experimental investigation.
  Medical physics 2012 Prakash P, Salgaonkar VA, Clif Burdette E, Diederich CJ
• Considerations for theoretical modelling of thermal ablation with catheter-based ultrasonic sources: implications for treatment planning, monitoring and control.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2012 Prakash P, Diederich CJ
• Temperature superposition for fast computation of 3D temperature distributions during optimization and planning of interstitial ultrasound hyperthermia treatments.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2012 Salgaonkar VA, Prakash P, Diederich CJ
• Implant strategies for endocervical and interstitial ultrasound hyperthermia adjunct to HDR brachytherapy for the treatment of cervical cancer.
  Physics in medicine and biology 2011 Wootton JH, Prakash P, Hsu IC, Diederich CJ
• Catheter-based ultrasound hyperthermia with HDR brachytherapy for treatment of locally advanced cancer of the prostate and cervix.
  Proceedings of SPIE--the International Society for Optical Engineering 2011 Diederich CJ, Wootton J, Prakash P, Salgaonkar V, Juang T, Scott S, Chen X, Cunha A, Pouliot J, Hsu IC
• Endocervical ultrasound applicator for integrated hyperthermia and HDR brachytherapy in the treatment of locally advanced cervical carcinoma.
  Medical physics 2011 Wootton JH, Hsu IC, Diederich CJ
• Percutaneous computed tomography fluoroscopy-guided conformal ultrasonic ablation of vertebral tumors in a rabbit tumor model. Laboratory investigation.
  Journal of neurosurgery. Spine 2010 Sciubba DM, Burdette EC, Cheng JJ, Pennant WA, Noggle JC, Petteys RJ, Alix C, Diederich CJ, Fichtinger G, Gokaslan ZL, Murphy KP
• Optimisation-based thermal treatment planning for catheter-based ultrasound hyperthermia.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2010 Chen X, Diederich CJ, Wootton JH, Pouliot J, Hsu IC
• Conformal microwave array (CMA) applicators for hyperthermia of diffuse chest wall recurrence.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2010 Stauffer PR, Maccarini P, Arunachalam K, Craciunescu O, Diederich C, Juang T, Rossetto F, Schlorff J, Milligan A, Hsu J, Sneed P, Vujaskovic Z
• Hyperthermia classic commentary: 'Arrhenius relationships from the molecule and cell to the clinic' by William Dewey, Int. J. Hyperthermia, 10:457-483, 1994.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2009 Dewey WC, Diederich CJ, Dewhirst MW
• Monitoring prostate thermal therapy with diffusion-weighted MRI.
  Magnetic resonance in medicine 2008 Chen J, Daniel BL, Diederich CJ, Bouley DM, van den Bosch MA, Kinsey AM, Sommer G, Pauly KB
• Transurethral ultrasound applicators with dynamic multi-sector control for prostate thermal therapy: in vivo evaluation under MR guidance.
  Medical physics 2008 Kinsey AM, Diederich CJ, Rieke V, Nau WH, Pauly KB, Bouley D, Sommer G
• Catheter-based ultrasound devices and MR thermal monitoring for conformal prostate thermal therapy.
  Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 2008 Diederich CJ, Nau WH, Kinsey A, Ross T, Wootton J, Juang T, Butts-Pauly K, Rieke V, Chen J, Bouley DM, Sommer G
• Prostate thermal therapy with high intensity transurethral ultrasound: the impact of pelvic bone heating on treatment delivery.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2007 Wootton JH, Ross AB, Diederich CJ
• Society of Thermal Medicine Robinson Award 2007.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2007 Diederich CJ
• Referenceless MR thermometry for monitoring thermal ablation in the prostate.
  IEEE transactions on medical imaging 2007 Rieke V, Kinsey AM, Ross AB, Nau WH, Diederich CJ, Sommer G, Pauly KB
• Intradiscal thermal therapy using interstitial ultrasound: an in vivo investigation in ovine cervical spine.
  Spine 2007 Nau WH, Diederich CJ, Shu R, Kinsey A, Bass E, Lotz J, Hu S, Simko J, Ferrier W, Sutton J, Attawia M, Pellegrino R
• Ultrasound interstitial thermal therapy (USITT) for the treatment of uterine myomas.
  Proceedings of SPIE--the International Society for Optical Engineering 2007 Nau WH, Diederich CJ, Simko J, Juang T, Jacoby A, Burdette EC
• Correlation of contrast-enhanced MR images with the histopathology of minimally invasive thermal and cryoablation cancer treatments in normal dog prostates.
  Proceedings of SPIE--the International Society for Optical Engineering 2007 Bouley DM, Daniel B, Pauly KB, Liu E, Kinsey A, Nau W, Diederich CJ, Sommer G
• Magnetic resonance-guided high-intensity ultrasound ablation of the prostate.
  Topics in magnetic resonance imaging : TMRI 2006 Pauly KB, Diederich CJ, Rieke V, Bouley D, Chen J, Nau WH, Ross AB, Kinsey AM, Sommer G
• Multisectored interstitial ultrasound applicators for dynamic angular control of thermal therapy.
  Medical physics 2006 Kinsey AM, Diederich CJ, Tyreus PD, Nau WH, Rieke V, Pauly KB
• Intradiscal thermal therapy does not stimulate biologic remodeling in an in vivo sheep model.
  Spine 2006 Bass EC, Nau WH, Diederich CJ, Liebenberg E, Shu R, Pellegrino R, Sutton J, Attawia M, Hu SS, Ferrier WT, Lotz JC
• Thermal ablation and high-temperature thermal therapy: overview of technology and clinical implementation.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2005 Diederich CJ
• Effects of spatial and temporal resolution for MR image-guided thermal ablation of prostate with transurethral ultrasound.
  Journal of magnetic resonance imaging : JMRI 2005 Pisani LJ, Ross AB, Diederich CJ, Nau WH, Sommer FG, Glover GH, Butts K
• Curvilinear transurethral ultrasound applicator for selective prostate thermal therapy.
  Medical physics 2005 Ross AB, Diederich CJ, Nau WH, Rieke V, Butts RK, Sommer G, Gill H, Bouley DM
• Feasibility of using interstitial ultrasound for intradiscal thermal therapy: a study in human cadaver lumbar discs.
  Physics in medicine and biology 2005 Nau WH, Diederich CJ, Shu R
• MRI-guided interstitial ultrasound thermal therapy of the prostate: a feasibility study in the canine model.
  Medical physics 2005 Nau WH, Diederich CJ, Ross AB, Butts K, Rieke V, Bouley DM, Gill H, Daniel B, Sommer G
• Catheter-based ultrasound applicators for selective thermal ablation: progress towards MRI-guided applications in prostate.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2004 Diederich CJ, Nau WH, Ross AB, Tyreus PD, Butts K, Rieke V, Sommer G
• Interleaved echo-planar imaging for fast multiplanar magnetic resonance temperature imaging of ultrasound thermal ablation therapy.
  Journal of magnetic resonance imaging : JMRI 2004 Stafford RJ, Price RE, Diederich CJ, Kangasniemi M, Olsson LE, Hazle JD
• Evaluation of temperature distributions in cadaveric lumbar spine during nucleoplasty.
  Physics in medicine and biology 2004 Nau WH, Diederich CJ
• Two-dimensional acoustic attenuation mapping of high-temperature interstitial ultrasound lesions.
  Physics in medicine and biology 2004 Tyréus PD, Diederich C
• Transurethral ultrasound applicators with directional heating patterns for prostate thermal therapy: in vivo evaluation using magnetic resonance thermometry.
  Medical physics 2004 Diederich CJ, Stafford RJ, Nau WH, Burdette EC, Price RE, Hazle JD
• Highly directional transurethral ultrasound applicators with rotational control for MRI-guided prostatic thermal therapy.
  Physics in medicine and biology 2004 Ross AB, Diederich CJ, Nau WH, Gill H, Bouley DM, Daniel B, Rieke V, Butts RK, Sommer G
• Evaluation of endorectal and urethral cooling devices during MR-guided ultrasound thermal ablation in canine prostate.
  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 2004 Nau WH, Diederich CJ, Ross AB, Rieke V, Butts K, Sommers G
• Interstitial ultrasound applicators with dynamic angular control for thermal ablation of tumors under MR-guidance.
  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 2004 Kinsey AM, Tyreus PD, Rieke V, Butts K, Nau WH, Sommer G, Diederich CJ
• MRI-temperature mapping during ultrasound prostate ablation using fat for phase estimation.
  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 2004 Rieke V, Ross AB, Nau WH, Diederich CJ, Sommer G, Butts K
• Temperature and thermal dose distributions during intradiscal electrothermal therapy in the cadaveric lumbar spine.
  Spine 2003 Kleinstueck FS, Diederich CJ, Nau WH, Puttlitz CM, Smith JA, Bradford DS, Lotz JC
• Effect of applicator diameter on lesion size from high temperature interstitial ultrasound thermal therapy.
  Medical physics 2003 Tyréus PD, Nau WH, Diederich CJ
• Multiplanar MR temperature-sensitive imaging of cerebral thermal treatment using interstitial ultrasound applicators in a canine model.
  Journal of magnetic resonance imaging : JMRI 2002 Kangasniemi M, Diederich CJ, Price RE, Stafford RJ, Schomer DF, Olsson LE, Tyreus PD, Nau WH, Hazle JD
• Theoretical model of internally cooled interstitial ultrasound applicators for thermal therapy.
  Physics in medicine and biology 2002 Tyréus PD, Diederich CJ
• MRI-guided thermal therapy of transplanted tumors in the canine prostate using a directional transurethral ultrasound applicator.
  Journal of magnetic resonance imaging : JMRI 2002 Hazle JD, Diederich CJ, Kangasniemi M, Price RE, Olsson LE, Stafford RJ
• Evaluation of multielement catheter-cooled interstitial ultrasound applicators for high-temperature thermal therapy.
  Medical physics 2001 Nau WH, Diederich CJ, Burdette EC
• Control of interstitial thermal coagulation: comparative evaluation of microwave and ultrasound applicators.
  Medical physics 2001 Deardorff DL, Diederich CJ, Nau WH
• Ultrasound applicators with internal water-cooling for high-powered interstitial thermal therapy.
  IEEE transactions on bio-medical engineering 2000 Deardorff DL, Diederich CJ
• Combination of transurethral and interstitial ultrasound applicators for high-temperature prostate thermal therapy.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2000 Diederich CJ, Nau WH, Burdette EC, Bustany IS, Deardorff DL, Stauffer PR
• Thermal and SAR characterization of multielement dual concentric conductor microwave applicators for hyperthermia, a theoretical investigation.
  Medical physics 2000 Rossetto F, Diederich CJ, Stauffer PR
• Directional power deposition from direct-coupled and catheter-cooled interstitial ultrasound applicators.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2000 Nau WH, Diederich CJ, Stauffer PR
• Axial control of thermal coagulation using a multi-element interstitial ultrasound applicator with internal cooling.
  IEEE transactions on ultrasonics, ferroelectrics, and frequency control 2000 Deardorff DL, Diederich CJ
• Novel catheter technology for ablative cure of atrial fibrillation.
  Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 2000 Lesh MD, Guerra P, Roithinger FX, Goseki Y, Diederich C, Nau WH, Maguire M, Taylor K
• An anatomic approach to prevention of atrial fibrillation: pulmonary vein isolation with through-the-balloon ultrasound ablation (TTB-USA).
  The Thoracic and cardiovascular surgeon 1999 Lesh MD, Diederich C, Guerra PG, Goseki Y, Sparks PB
• Ultrasound technology for hyperthermia.
  Ultrasound in medicine & biology 1999 Diederich CJ, Hynynen K
• Angular directivity of thermal coagulation using air-cooled direct-coupled interstitial ultrasound applicators.
  Ultrasound in medicine & biology 1999 Deardorff DL, Diederich CJ
• Ultrasound applicators for interstitial thermal coagulation.
  IEEE transactions on ultrasonics, ferroelectrics, and frequency control 1999 Diederich CJ, Nau WH, Stauffer PR
• Air-cooling of direct-coupled ultrasound applicators for interstitial hyperthermia and thermal coagulation.
  Medical physics 1998 Deardorff DL, Diederich CJ, Nau WH
• Effect of practical layered dielectric loads on SAR patterns from dual concentric conductor microstrip antennas.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1998 Rossetto F, Stauffer PR, Manfrini V, Diederich CJ, Biffi Gentili G
• Minimax optimization-based inverse treatment planning for interstitial thermal therapy.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1998 Khalil-Bustany IS, Diederich CJ, Polak E, Kirjner-Neto C
• Survival benefit of hyperthermia in a prospective randomized trial of brachytherapy boost +/- hyperthermia for glioblastoma multiforme.
  International journal of radiation oncology, biology, physics 1998 Sneed PK, Stauffer PR, McDermott MW, Diederich CJ, Lamborn KR, Prados MD, Chang S, Weaver KA, Spry L, Malec MK, Lamb SA, Voss B, Davis RL, Wara WM, Larson DA, Phillips TL, Gutin PH
• Direct-coupled interstitial ultrasound applicators for simultaneous thermobrachytherapy: a feasibility study.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1996 Diederich CJ, Khalil IS, Stauffer PR, Sneed PK, Phillips TL
• Interstitial ultrasound applicators are practical from an engineering perspective for treating large tumours.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1996 Diederich CJ
• Ultrasound applicators with integrated catheter-cooling for interstitial hyperthermia: theory and preliminary experiments.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1996 Diederich CJ
• An improved bolus configuration for commercial multielement ultrasound and microwave hyperthermia systems.
  Medical physics 1994 Diederich CJ, Stauffer PR, Bozzo D
• Pre-clinical evaluation of a microwave planar array applicator for superficial hyperthermia.
  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1993 Diederich CJ, Stauffer PR
• The feasibility of using electrically focused ultrasound arrays to induce deep hyperthermia via body cavities.
  IEEE transactions on ultrasonics, ferroelectrics, and frequency control 1991 Diederich CJ, Hynynen K
• The development of intracavitary ultrasonic applicators for hyperthermia: a design and experimental study.
  Medical physics 1990 Diederich CJ, Hynynen K
• Induction of hyperthermia using an intracavitary multielement ultrasonic applicator.
  IEEE transactions on bio-medical engineering 1989 Diederich CJ, Hynynen K
• A spherical source model for the thermal pulse decay method of measuring blood perfusion: a sensitivity analysis.
  Journal of biomechanical engineering 1989 Diederich CJ, Clegg S, Roemer RB