Christian Cordano, MD, PhD
Associate Researcher
Neurology
School of Medicine

Dr. Cordano subsequently decided to focus his career on MS research, coupling his dual passions for neuro-ophthalmology and neuroimmunology. He joined Dr. Ari Green´s Lab at UCSF as a Postdoctoral Research Fellow in August 2014, funded by a fellowship from FISM (Italian Multiple Sclerosis Foundation).

His work is focused on visual electrophysiologic alteration in Experimental Autoimmune Encephalomyelitis models, trying to characterize the course of electrophysiologic alterations and neuronal injury following demyelination. He completed his PhD in the Department of Experimental Medicine at the University of Genoa in April 2017, and will also complete a degree in Economics. Dr. Cordano grew up in Genoa. In his free time, he loves to travel, cheer on his soccer team (Genoa), and read comics and classics.

• Serum sickness in a multiple sclerosis patient treated with ocrelizumab.
  Journal of neurology 2023 Mantero V, Cordano C, Balgera R, Basilico P, Novi G, Salmaggi A
• Remyelination protects neurons from DLK-mediated neurodegeneration.
  bioRxiv : the preprint server for biology 2023 Duncan GJ, Ingram SD, Emberley K, Hill J, Cordano C, Abdelhak A, McCane M, Jabassini N, Ananth K, Ferrara SJ, Stedelin B, Sivyer B, Aicher SA, Scanlan T, Watkins TA, Mishra A, Nelson J, Green AJ, …
• Flu-like syndrome due to interferon-beta injections does not increase anxiety, depression, and lost working days in multiple sclerosis patients during the Sars-CoV-2 pandemic.
  Clinical neurology and neurosurgery 2023 Mantero V, Basilico P, Balgera R, Rigamonti A, Sozzi M, Salmaggi A, Cordano C
• Editorial: CSF and blood biomarkers in COVID-19 and other neuroinfectious diseases.
  Frontiers in neurology 2023 Foschi M, Abu-Rumeileh S, Massa F, Cordano C, Abdelhak A
• Imaging immunomodulatory treatment responses in a multiple sclerosis mouse model using hyperpolarized 13C metabolic MRI.
  Communications medicine 2023 Guglielmetti C, Cordano C, Najac C, Green AJ, Chaumeil MM
• MWF of the corpus callosum is a robust measure of remyelination: Results from the ReBUILD trial.
  Proceedings of the National Academy of Sciences of the United States of America 2023 Caverzasi E, Papinutto N, Cordano C, Kirkish G, Gundel TJ, Zhu A, Akula AV, Boscardin WJ, Neeb H, Henry RG, Chan JR, Green AJ
• Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination.
  The Journal of clinical investigation 2023 Kapell H, Fazio L, Dyckow J, Schwarz S, Cruz-Herranz A, Mayer C, Campos J, D'Este E, Möbius W, Cordano C, Pröbstel AK, Gharagozloo M, Zulji A, Narayanan Naik V, Delank A, Cerina M, Müntefering T, …
• Visually Evoked Potential as Prognostic Biomarker for Neuroaxonal Damage in Multiple Sclerosis From a Multicenter Longitudinal Cohort.
  Neurology(R) neuroimmunology & neuroinflammation 2023 Oertel FC, Krämer J, Motamedi S, Keihani A, Zimmermann HG, Dimitriou NG, Condor-Montes S, Bereuter C, Cordano C, Abdelhak A, Trip A, Aktas O, Meuth SG, Wiendl H, Ruprecht K, Bellmann-Strobl J, Paul F,…
• Validating visual evoked potentials as a preclinical, quantitative biomarker for remyelination efficacy.
  Brain : a journal of neurology 2022 Cordano C, Sin JH, Timmons G, Yiu HH, Stebbins K, Guglielmetti C, Cruz-Herranz A, Xin W, Lorrain D, Chan JR, Green AJ
• Erratum: Choroidal Thickness in Multiple Sclerosis: An Optical Coherence Tomography Study.
  Journal of clinical neurology (Seoul, Korea) 2022 Masala A, Mola ID, Cellerino M, Pera V, Vagge A, Uccelli A, Cordano C, Traverso CE, Iester M
• Differences in Age-related Retinal and Cortical Atrophy Rates in Multiple Sclerosis.
  Neurology 2022 Cordano C, Nourbakhsh B, Yiu HH, Papinutto N, Caverzasi E, Abdelhak A, Oertel FC, Beaudry-Richard A, Santaniello A, Sacco S, Bennett DJ, Gomez A, Sigurdson CJ, Hauser SL, Magliozzi R, Cree BAC, Henry …
• Retinal arteriolar parameters as a surrogate marker of intracranial vascular pathology.
  Alzheimer's & dementia (Amsterdam, Netherlands) 2022 Abdelhak A, Solomon I, Montes SC, Saias A, Cordano C, Asken B, Fonseca C, Oertel FC, Arfanakis K, Staffaroni AM, Kramer JH, Geschwind M, Miller BL, Elahi FM, Green AJ
• Plasma neurofilament light chain levels suggest neuroaxonal stability following therapeutic remyelination in people with multiple sclerosis.
  Journal of neurology, neurosurgery, and psychiatry 2022 Abdelhak A, Cordano C, Boscardin WJ, Caverzasi E, Kuhle J, Chan B, Gelfand JM, Yiu HH, Oertel FC, Beaudry-Richard A, Condor Montes S, Oksenberg JR, Lario Lago A, Boxer A, Rojas-Martinez JC, Elahi FM, …
• Delineating the anatomical basis of microsaccades using an ultrasensitive technique for detection of deficits in patients with MS (P15-12.002).
  Neurology 2022 Christy Sheehy, Eduardo Caverzasi, Christian Cordano, Ari Green
• Differences in age-related retinal and cortical atrophy rates in multiple sclerosis (S26.002).
  Neurology 2022 Christian Cordano, Bardia Nourbakhsh, Hao Yiu, Nico Papinutto, Eduardo Caverzasi, Ahmed Abdelhak, Frederike Cosima Oertel, Alexandra Beaudry-Richard, Adam Santaniello, Simone Sacco, Daniel Bennett, …
• Reply to "Interpretation of Longitudinal Changes of the Inner Nuclear Layer in MS".
  Annals of neurology 2022 Cordano C, Yiu HH, Abdelhak A, Beaudry-Richard A, Oertel FC, Green AJ
• Substance Use-Related Cognitive Decline in Families with Autosomal Dominant Alzheimer's Disease: A Cohort Study.
  Journal of Alzheimer's disease : JAD 2022 Ramos C, Villalba C, García J, Lanata S, López H, Aguillón D, Cordano C, Madrigal L, Aguirre-Acevedo DC, Lopera F
• Changes in wall thickness of retinal arterioles as a surrogate marker of intracranial vascular pathology.
  Alzheimer's & Dementia 2021 Ahmed Abdelhak, Isaac Solomon, Alexandra Saias, Shivany Condor Montes, Christian Cordano, Breton Asken, Corrina Fonseca, Frederike Cosima Oertel, Konstantinos Arfanakis, Adam M. Staffaroni, Michael …
• Retinal biomarkers predict future cognitive performance in progranulin-haploinsufficient frontotemporal dementia.
  Alzheimer's & Dementia 2021 Frederike Cosima Oertel, Kyan Younes, Yann Cobigo, Azeen Keihani, Corrina Fonseca, Daniel J Bennett, Ahmed Abdelhak, Alexandra Saias, Shivany Condor Montes, Robert Y Chen, Christian Cordano, Ari J …
• Visuocognitive impairment in multiple sclerosis: The relationship between neuropsychological and evoked potential measures.
  Journal of the Neurological Sciences 2021 Christian Cordano, Luca Mazzella, Carla Ogliastro, Maria Cellerino, Lucilla Vestito, Fabio Bandini
• Distinctive waves of innate immune response in the retina in experimental autoimmune encephalomyelitis.
  JCI insight 2021 Cruz-Herranz A, Oertel FC, Kim K, Cantó E, Timmons G, Sin JH, Devereux M, Baker N, Michel B, Schubert RD, Rani L, Cordano C, Baranzini SE, Green AJ
• Multiple Sclerosis Is Rare in Epstein-Barr Virus-Seronegative Children with Central Nervous System Inflammatory Demyelination.
  Annals of neurology 2021 Nourbakhsh B, Cordano C, Asteggiano C, Ruprecht K, Otto C, Rutatangwa A, Lui A, Hart J, Flanagan EP, James JA, Waubant E
• Multiple sclerosis and COVID-19: How could therapeutic scenarios change during the pandemic?
  Journal of medical virology 2021 Mantero V, Abate L, Salmaggi A, Cordano C
• Safety and efficacy of amantadine, modafinil, and methylphenidate for fatigue in multiple sclerosis: a randomised, placebo-controlled, crossover, double-blind trial.
  The Lancet. Neurology 2020 Nourbakhsh B, Revirajan N, Morris B, Cordano C, Creasman J, Manguinao M, Krysko K, Rutatangwa A, Auvray C, Aljarallah S, Jin C, Mowry E, McCulloch C, Waubant E
• Inflammation in the anterior visual pathway in multiple sclerosis: what do the animal models teach us?.
  Neuroimmunology and Neuroinflammation 2020 Christian Cordano, Claudia Ramos, Sam Arnow, Andrés Cruz-Herranz, Caroline Guglielmetti, Michele Iester, Fabio Bandini
• Retinal INL Thickness in Multiple Sclerosis: A Mere Marker of Neurodegeneration?
  Annals of neurology 2020 Cordano C, Yiu HH, Oertel FC, University of California, San Francisco MS-EPIC Team, Gelfand JM, Hauser SL, Cree BAC, Green AJ
• Contrast-induced encephalopathy mimicking total anterior circulation stroke: a case report and review of the literature.
  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2020 Vigano' M, Mantero V, Basilico P, Cordano C, Sangalli D, Reganati P, Lunghi A, Rigamonti A, Salmaggi A
• Corneal epithelial dendritic cells in patients with multiple sclerosis: An in vivo confocal microscopy study.
  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2020 Testa V, De Santis N, Scotto R, Della Giustina P, Ferro Desideri L, Cellerino M, Cordano C, Inglese M, Uccelli A, Vagge A, Traverso CE, Iester M
• Mild COVID-19 infection in a group of teriflunomide-treated patients with multiple sclerosis.
  Journal of neurology 2020 Mantero V, Baroncini D, Balgera R, Guaschino C, Basilico P, Annovazzi P, Zaffaroni M, Salmaggi A, Cordano C
• Assessing the susceptibility to acute respiratory illness COVID-19-related in a cohort of multiple sclerosis patients.
  Multiple sclerosis and related disorders 2020 Mantero V, Abate L, Balgera R, Basilico P, Salmaggi A, Cordano C
• Imaging correlates of visual function in multiple sclerosis.
  PloS one 2020 Caverzasi E, Cordano C, Zhu AH, Zhao C, Bischof A, Kirkish G, Bennett DJ, Devereux M, Baker N, Inman J, Yiu HH, Papinutto N, Gelfand JM, Cree BAC, Hauser SL, Henry RG, Green AJ
• MRI Measurement of Upper Cervical Spinal Cord Cross-Sectional Area in Children.
  Journal of neuroimaging : official journal of the American Society of Neuroimaging 2020 Papinutto N, Cordano C, Asteggiano C, Caverzasi E, Mandelli ML, Lauricella M, Yabut N, Neylan M, Kirkish G, Gorno-Tempini ML, Henry RG
• Genetics of dementia: insights from Latin America.
  Dementia & neuropsychologia 2020 Ramos C, Aguillon D, Cordano C, Lopera F
• COVID-19 in dimethyl fumarate-treated patients with multiple sclerosis.
  Journal of neurology 2020 Mantero V, Abate L, Basilico P, Balgera R, Salmaggi A, Nourbakhsh B, Cordano C
• Fixational microsaccades: A quantitative and objective measure of disability in multiple sclerosis.
  Multiple sclerosis (Houndmills, Basingstoke, England) 2020 Sheehy CK, Bensinger ES, Romeo A, Rani L, Stepien-Bernabe N, Shi B, Helft Z, Putnam N, Cordano C, Gelfand JM, Bove R, Stevenson SB, Green AJ
• Monitoring retinal changes with optical coherence tomography predicts neuronal loss in experimental autoimmune encephalomyelitis.
  Journal of neuroinflammation 2019 Cruz-Herranz A, Dietrich M, Hilla AM, Yiu HH, Levin MH, Hecker C, Issberner A, Hallenberger A, Cordano C, Lehmann-Horn K, Balk LJ, Aktas O, Ingwersen J, von Gall C, Hartung HP, Zamvil SS, Fischer D, …
• Relationship between retinal inner nuclear layer, age, and disease activity in progressive MS.
  Neurology(R) neuroimmunology & neuroinflammation 2019 Cellerino M, Cordano C, Boffa G, Bommarito G, Petracca M, Sbragia E, Novi G, Lapucci C, Capello E, Uccelli A, Inglese M
• pRNFL as a marker of disability worsening in the medium/long term in patients with MS.
  Neurology(R) neuroimmunology & neuroinflammation 2018 Cordano C, Nourbakhsh B, Devereux M, Damotte V, Bennett D, Hauser SL, Cree BAC, Gelfand JM, Green AJ
• Prion Seeds Distribute throughout the Eyes of Sporadic Creutzfeldt-Jakob Disease Patients.
  mBio 2018 Orrù CD, Soldau K, Cordano C, Llibre-Guerra J, Green AJ, Sanchez H, Groveman BR, Edland SD, Safar JG, Lin JH, Caughey B, Geschwind MD, Sigurdson CJ
• Acquired Hepatocerebral Degeneration in the Absence of Portosystemic Shunting.
  Journal of clinical neurology (Seoul, Korea) 2018 Caranci G, Cordano C, Giannini E, Bandini F
• Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity.
  eLife 2018 Schirmer L, Möbius W, Zhao C, Cruz-Herranz A, Ben Haim L, Cordano C, Shiow LR, Kelley KW, Sadowski B, Timmons G, Pröbstel AK, Wright JN, Sin JH, Devereux M, Morrison DE, Chang SM, Sabeur K, Green AJ, …
• Determining the Etiology of Internuclear Ophthalmoplegia in a Patient with a Cardiac Pacemaker and Complex Neurological Presentation.
  Journal of clinical neurology (Seoul, Korea) 2018 Nourbakhsh B, Cordano C, Renthal W
• Osteopathic Manipulative Therapy and Multiple Sclerosis: A Proof-of-Concept Study.
  The Journal of the American Osteopathic Association 2018 Cordano C, Armezzani A, Veroni J, Pardini M, Sassos D, Infante MT, Tacchino A, Lapucci C, Cellerino M, Calabrò V, Ciullo L, Nourbakhsh B
• Evaluation of the association between sexual dysfunction and demyelinating plaque location and number in female multiple sclerosis patients.
  Neurological research 2018 Solmaz V, Ozlece HK, Him A, Günes A, Cordano C, Aksoy D, Çelik Y
• MRI Findings in Varicella Zoster Trigeminal Neuritis Without Rash.
  Headache 2018 Cordano C, Caverzasi E, Spigno L, De Maria A, Bandini F
• Motor Imagery as a Function of Disease Severity in Multiple Sclerosis: An fMRI Study.
  Frontiers in human neuroscience 2018 Tacchino A, Saiote C, Brichetto G, Bommarito G, Roccatagliata L, Cordano C, Battaglia MA, Mancardi GL, Inglese M
• Advances in Imaging Multiple Sclerosis.
  Seminars in neurology 2017 Bischof A, Caverzasi E, Cordano C, Hauser SL, Henry RG
• Occipital Headache in Chronic Lymphocytic Inflammation With Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS).
  Headache 2017 Cordano C, López GY, Bollen AW, Nourbakhsh B
• Retinal layer segmentation in multiple sclerosis: a systematic review and meta-analysis.
  The Lancet. Neurology 2017 Petzold A, Balcer LJ, Calabresi PA, Costello F, Frohman TC, Frohman EM, Martinez-Lapiscina EH, Green AJ, Kardon R, Outteryck O, Paul F, Schippling S, Vermersch P, Villoslada P, Balk LJ, ERN-EYE …
• Extensive Involvement of Multiple Cranial and Spinal Nerves in Lymphomatous Meningitis – ERRATUM.
  Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 2017 Christian Cordano, Bardia Nourbakhsh, Ethan Brown, Christine Glastonbury
• Extensive Involvement of Multiple Cranial and Spinal Nerves in Lymphomatous Meningitis.
  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2017 Cordano C, Nourbakhsh B, Brown E, Glastonbury C
• pRNFL as a predictor of medium/long term disability in MS patients (P6.031).
  Neurology 2017 Christian Cordano, Vincent Damotte, Michael Devereux, Nicholas Baker, Riley Bove, Carolyn Bevan, Liz Crabtree-Hartman, Bruce Cree, Douglas Goodin, Jennifer Graves, Jill Hollenbach, Stephen Hauser, …
• Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis.
  Science translational medicine 2017 Ward ME, Chen R, Huang HY, Ludwig C, Telpoukhovskaia M, Taubes A, Boudin H, Minami SS, Reichert M, Albrecht P, Gelfand JM, Cruz-Herranz A, Cordano C, Alavi MV, Leslie S, Seeley WW, Miller BL, Bigio E,…
• Homonymous hemianopia as the first sign of posterior cortical atrophy.
  Journal of the neurological sciences 2016 Cordano C, Alessandria G, Leonardi A, Cellerino M, Nourbakhsh B, Nobili F, Bandini F
• Resting-state functional connectivity and motor imagery brain activation.
  Human brain mapping 2016 Saiote C, Tacchino A, Brichetto G, Roccatagliata L, Bommarito G, Cordano C, Battaglia M, Mancardi GL, Inglese M
• Retinal degeneration in primary-progressive multiple sclerosis: A role for cortical lesions?
  Multiple sclerosis (Houndmills, Basingstoke, England) 2016 Petracca M, Cordano C, Cellerino M, Button J, Krieger S, Vancea R, Ghassemi R, Farrell C, Miller A, Calabresi PA, Lublin F, Inglese M
• Effectiveness of Time Domain and Spectral Domain Optical Coherence Tomograph to Evaluate Eyes with And Without Optic Neuritis in Multiple Sclerosi Patients.
  Journal of Multiple Sclerosis 2016 M Iester, C Cordano
• Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: a cohort study.
  The Lancet. Neurology 2016 Martinez-Lapiscina EH, Arnow S, Wilson JA, Saidha S, Preiningerova JL, Oberwahrenbrock T, Brandt AU, Pablo LE, Guerrieri S, Gonzalez I, Outteryck O, Mueller AK, Albrecht P, Chan W, Lukas S, Balk LJ, …
• Effectiveness of Time Domain and Spectral Domain Optical Coherence Tomograph to Evaluate Eyes with And Without Optic Neuritis in Multiple Sclerosi Patients.
  Journal of Multiple Sclerosis 2016 Iester M, Cordano C
• Parkinson's Disease Sleep Scale 2: application in an Italian population.
  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2015 Arnaldi D, Cordano C, De Carli F, Accardo J, Ferrara M, Picco A, Tamburini T, Brugnolo A, Abbruzzese G, Nobili F
• Pisa syndrome in Parkinson disease: An observational multicenter Italian study.
  Neurology 2015 Tinazzi M, Fasano A, Geroin C, Morgante F, Ceravolo R, Rossi S, Thomas A, Fabbrini G, Bentivoglio A, Tamma F, Cossu G, Modugno N, Zappia M, Volontè MA, Dallocchio C, Abbruzzese G, Pacchetti C, Marconi…
• Prevalence and cognitive underpinnings of isolated apathy in young healthy subjects.
  Journal of affective disorders 2015 Pardini M, Cordano C, Guida S, Grafman J, Krueger F, Sassos D, Massucco D, Abate L, Yaldizli Ö, Serrati C, Amore M, Mattei C, Cocito L, Emberti Gialloreti L
• Fumarates modulate microglia activation through a novel HCAR2 signaling pathway and rescue synaptic dysregulation in inflamed CNS.
  Acta neuropathologica 2015 Parodi B, Rossi S, Morando S, Cordano C, Bragoni A, Motta C, Usai C, Wipke BT, Scannevin RH, Mancardi GL, Centonze D, Kerlero de Rosbo N, Uccelli A
• Relationship between RNFL thickness and Brain Cortical Lesions in Primary-Progressive MS (P6.109).
  Neurology 2015 Christian Cordano, Maria Petracca, Phillip Rubin, Colleen Farrell, Aaron Miller, Fred Lublin, Matilde Inglese
• Levodopa-induced neutropenia.
  Parkinsonism & related disorders 2015 Cordano C, Pardini M, Cellerino M, Schenone A, Marino F, Cosentino M
• Monomethyl fumarate inhibits the NFkB pathway and pro-inflammatory cytokine expression in microglia through HCA2 signaling via the AMPK/Sirt axis.
  Journal of Neuroimmunology 2014 Benedetta Parodi, Christian Cordano, Sara Morando, Alberto Bragoni, Debora Giunti, Cesare Usai, Diego Centonze, Nicole Kerlero De Rosbo, Robert H. Scannevin, Antonio Uccelli
• Recurring hyperammonemic encephalopathy induced by bacteria usually not producing urease.
  BMC research notes 2014 Cordano C, Traverso E, Calabrò V, Borzone C, Stara S, Marchese R, Marinelli L
• Electroretinographic modifications induced by agomelatine: a novel avenue to the understanding of the claimed antidepressant effect of the drug?
  Neuropsychiatric disease and treatment 2014 Fornaro M, Bandini F, Cestari L, Cordano C, Ogliastro C, Albano C, De Berardis D, Martino M, Escelsior A, Rocchi G, Fornaro P, De Pasquale C
• Can we switch microglia's phenotype to foster neuroprotection? Focus on multiple sclerosis.
  Immunology 2014 Giunti D, Parodi B, Cordano C, Uccelli A, Kerlero de Rosbo N
• Agomelatine but not melatonin improves fatigue perception: a longitudinal proof-of-concept study.
  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2014 Pardini M, Cordano C, Benassi F, Mattei C, Sassos D, Guida S, Serrati C, Primavera A, Amore M, Cocito L, Emberti Gialloreti L
• Takotsubo cardiomyopathy and torsade de pointes in myasthenic crisis: be aware of QT prolongation.
  The American journal of emergency medicine 2013 Valbusa A, Ingrassia S, Rosa GM, Infante MT, Schenone A, Montecucco F, Cordano C
• 10 Mesenchymal stem cells as a strategy for the treatment of multiple sclerosis and other diseases of the central nervous system.
  Stem Cell-Dependent Therapies 2013 Christian Cordano, Nicole Kerlero de Rosbo, Antonio Uccelli
• Electroretinographic assessment in major depressed patients receiving duloxetine: might differences between responders and non-responders indicate a differential biological background?
  Journal of affective disorders 2011 Fornaro M, Bandini F, Ogliastro C, Cordano C, Martino M, Cestari L, Escelsior A, Rocchi G, Colicchio S, Perugi G