Chimno Nnadi, MD
RESIDENT
Psychiatry
School of Medicine

Awards

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• APA Research Colloquium for Junior Investigators, 2025
• UCSF Clinical and Translational Science Institute Resident Research Training Program Travel Award, 2025
• Ruth L. Kirschstein National Research Service Award F30 Fellow, 2017-2020
• Phi Beta Kappa, 2012
• Barry M. Goldwater Scholarship, 2011

Education & Training

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• B.A. Chemistry Columbia University
• Ph.D Chemistry and Chemical Biology University of California, San Francisco
• M.D. Medicine University of California, San Francisco
• Residency Psychiatry University of California, San Francisco

Grants and Projects

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• Development of covalent docking to identify new cysteine-targeted K-Ras inhibitors to address allelic variation in cancer, NIH, 2017-2020

Publications (3)

Top publication keywords:
Drug DiscoveryMutant ProteinsNucleotidesBiophysical PhenomenaHypoxia-Inducible Factor-Proline DioxygenasesRetinoblastoma-Binding Protein 2Mass SpectrometryProtein ConformationDNA Mutational AnalysisGene Expression Regulation, NeoplasticMolecular Docking SimulationSaccharomyces cerevisiaeUbiquitinras ProteinsStress, Physiological

• Novel K-Ras G12C Switch-II Covalent Binders Destabilize Ras and Accelerate Nucleotide Exchange.
  Journal of chemical information and modeling 2018 Nnadi CI, Jenkins ML, Gentile DR, Bateman LA, Zaidman D, Balius TE, Nomura DK, Burke JE, Shokat KM, London N
• Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting.
  eLife 2016 Mavor D, Barlow K, Thompson S, Barad BA, Bonny AR, Cario CL, Gaskins G, Liu Z, Deming L, Axen SD, Caceres E, Chen W, Cuesta A, Gate RE, Green EM, Hulce KR, Ji W, Kenner LR, Mensa B, Morinishi LS, Moss…
• Histone demethylase KDM5A is regulated by its reader domain through a positive-feedback mechanism.
  Nature communications 2015 Torres IO, Kuchenbecker KM, Nnadi CI, Fletterick RJ, Kelly MJ, Fujimori DG