Cheryl Peretz, MD
Assistant Professor
Pediatrics
School of Medicine

Publications (8)

Top publication keywords:
Drug Resistance, NeoplasmSequence Analysis, DNAMicrofluidicsGenetic Association StudiesProtein Kinase InhibitorsApoptosisBenzothiazolesras ProteinsHigh-Throughput Nucleotide SequencingAniline CompoundsPhenylurea CompoundsLeukemia, Myeloid, Acutefms-Like Tyrosine Kinase 3Clonal EvolutionSingle-Cell Analysis

• LNK/SH2B3 as a novel driver in juvenile myelomonocytic leukemia.
  Haematologica 2023 Wintering A, Hecht A, Meyer J, Wong EB, Hübner J, Abelson S, Feldman K, Kennedy VE, Peretz CAC, French DL, Maguire JA, Jobaliya C, Vasquez MR, Desai S, Dulman R, Nemecek E, Haines H, Hammad M, El …
• Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML.
  Cell reports. Medicine 2023 Popescu B, Stahlhut C, Tarver TC, Wishner S, Lee BJ, Peretz CAC, Luck C, Phojanakong P, Camara Serrano JA, Hongo H, Rivera JM, Xirenayi S, Chukinas JA, Steri V, Tasian SK, Stieglitz E, Smith CC
• The FLT3N701K mutation causes clinical AML resistance to gilteritinib and triggers TKI sensitivity switch to quizartinib.
  American journal of hematology 2023 Joshi SK, Pittsenbarger J, Kennedy VE, Peretz CAC, Perl AE, Smith CC, Tyner JW, Druker BJ, Traer E
• Multiomic Single Cell Sequencing Identifies Stemlike Nature of Mixed Phenotype Acute Leukemia and Provides Novel Risk Stratification.
  bioRxiv : the preprint server for biology 2023 Peretz CAC, Kennedy VE, Walia A, Delley CL, Koh A, Tran E, Clark IC, Hayford CE, D'Amato C, Xue Y, Fontanez KM, Roy R, Logan AC, Perl AE, Abate A, Olshen A, Smith CC
• Microfluidics-free single-cell genomics with templated emulsification.
  Nature biotechnology 2023 Clark IC, Fontanez KM, Meltzer RH, Xue Y, Hayford C, May-Zhang A, D'Amato C, Osman A, Zhang JQ, Hettige P, Ishibashi JSA, Delley CL, Weisgerber DW, Replogle JM, Jost M, Phong KT, Kennedy VE, Peretz …
• Joint profiling of DNA and proteins in single cells to dissect genotype-phenotype associations in leukemia.
  Nature communications 2021 Demaree B, Delley CL, Vasudevan HN, Peretz CAC, Ruff D, Smith CC, Abate AR
• Single-cell DNA sequencing reveals complex mechanisms of resistance to quizartinib.
  Blood advances 2021 Peretz CAC, McGary LHF, Kumar T, Jackson H, Jacob J, Durruthy-Durruthy R, Levis MJ, Perl A, Huang BJ, Smith CC
• Clonal Selection with RAS Pathway Activation Mediates Secondary Clinical Resistance to Selective FLT3 Inhibition in Acute Myeloid Leukemia.
  Cancer discovery 2019 McMahon CM, Ferng T, Canaani J, Wang ES, Morrissette JJD, Eastburn DJ, Pellegrino M, Durruthy-Durruthy R, Watt CD, Asthana S, Lasater EA, DeFilippis R, Peretz CAC, McGary LHF, Deihimi S, Logan AC, …