Catherine Ines Tcheandjieu Gueliatcha, PhD
Assistant Professor
Epidemiology & Biostatistics
School of Medicine

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• Catherine-tcheandjieu (tcheandjieulab.gladstone.org)

Publications (54)

Top publication keywords:
AortaPolymorphism, Single NucleotideChromosomes, Human, Pair 9Carotid Artery DiseasesBiological Variation, PopulationCoronary Artery DiseaseGenome-Wide Association StudyMendelian Randomization AnalysisMultifactorial InheritanceThyroid NeoplasmsAortic AneurysmInheritance PatternsGlutathione TransferaseGenetic Association StudiesChromosomes, Human, Pair 14

• Angiographic Burden of Coronary Atherosclerosis Partially Mediates the Association Between ASCVD Risk Factors and Outcomes.
  Circulation. Genomic and precision medicine 2026 Tsao NL, Abramowitz SA, Shakt GE, Judy R, Hilliard AT, Damrauer SM, Assimes TL, Clarke SL, Tcheandjieu C, Levin MG, Penn Medicine Biobank
• KidneyGenAfrica multi-cohort Genome-wide association study and polygenic prediction of kidney function in 110,000 Africans.
  Nature communications 2026 Kamiza AB, Chikowore T, Chen G, Ojewunmi O, Machipisa T, Zhou F, Mayanja R, Toure S, Soremekun O, Kintu C, Nakabuye M, Koprulu M, Kalungi A, Kalyesubula R, Salako B, Nashiru O, Corpas M, Robinson-…
• A Genome-Wide Association Study of Hidradenitis Suppurativa from the VA's Million Veteran Program.
  Dermatology (Basel, Switzerland) 2026 Wendland ZD, Teerlink CC, Pridgen KM, Lo S, Sayed C, van Straalen KR, Tcheandjieu C, Tsao PS, Chang KM, Li Y, Mohlke KL, Sun Q, Lynch JA, Goldfarb N
• Systemic Manifestations and Mortality Risk in Transthyretin V142I Variant Carriers: A Million Veteran Program Analysis.
  JACC. CardioOncology 2026 Sideris K, Nelson TJ, Brinker L, Gao A, Tcheandjieu C, Kyriakopoulos CP, Berlowitz D, Hull L, Ferraro JP, Agiri FY, Pridgen KM, Roblin S, Joseph J, Damrauer SM, Chang KM, Teerlink CC, Stehlik J, …
• Risk of Systemic Manifestations in Homozygous Carriers of the Transthyretin V142I Variant: A Million Veteran Program Analysis.
  Journal of the American Heart Association 2025 Sideris K, Nelson TJ, Brinker L, Gao A, Tcheandjieu C, Kyriakopoulos CP, Berlowitz D, Hull L, Ferraro JP, Agiri FY, Pridgen KM, Roblin S, Joseph J, Levin MG, Damrauer SM, Chang KM, Teerlink CC, …

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• Mendelian Randomization Suggests a Causal Link Between Glycemic Traits and Thoracic Aortic Structures and Diseases.
  JACC. Basic to translational science 2025 Daria T, Iyer K, Alkhairo H, Kho PF, Suzuki K, Hatzikotoulas K, Southam L, Taylor HJ, Yin X, Mandla R, Huerta-Chagoya A, Rayner WN, Levin MG, Damrauer SM, Tsao PS, Priest JR, Klarin D, Pirruccello J, …
• Polygenic prediction of body mass index and obesity through the life course and across ancestries.
  Nature medicine 2025 Smit RAJ, Wade KH, Hui Q, Arias JD, Yin X, Christiansen MR, Yengo L, Preuss MH, Nakabuye M, Rocheleau G, Graham SE, Buchanan VL, Chittoor G, Graff M, Guindo-Martínez M, Lu Y, Marouli E, Sakaue S, …
• A genome-wide association study of hidradenitis suppurativa from the VA's Million Veteran Program.
  medRxiv : the preprint server for health sciences 2025 Wendland Z, Teerlink CC, Pridgen KM, Lo S, Sayed C, Van Straalen KR, Tcheandjieu C, Tsao PS, Chang KM, Li Y, Mohlke KL, Sun Q, Lynch JA, Goldfarb N
• Bench to all Bedsides in Genomics and Precision Medicine.
  Journal of the American Heart Association 2025 Tcheandjieu C, Robinson C, Natarajan P
• Cross-Ancestry Associations of Spontaneous Coronary Artery Dissection Genetic Risk With Coronary Atherosclerosis and Migraine Headache.
  Journal of the American Heart Association 2025 Xu C, Yang ML, Kho PF, Clarke SL, Tcheandjieu C, Peyser PA, Fann CS, Chen SP, VA Million Veteran Program, Saw J, Zhou X, Assimes TL, Ganesh SK
• Premorbid predictors of death at initial presentation of coronary heart disease in the Women's Health Initiative study.
  American journal of preventive cardiology 2025 Chen ML, Li J, Iyer KR, Tcheandjieu C, Jimenez S, Salfati ELI, Del Gobbo LC, Stefanick ML, Desai M, Xue X, Assimes TL
• Rare variant contribution to the heritability of coronary artery disease.
  Nature communications 2024 Rocheleau G, Clarke SL, Auguste G, Hasbani NR, Morrison AC, Heath AS, Bielak LF, Iyer KR, Young EP, Stitziel NO, Jun G, Laurie C, Broome JG, Khan AT, Arnett DK, Becker LC, Bis JC, Boerwinkle E, Bowden…
• Genetic risk and likelihood of prostate cancer detection on first biopsy by ancestry.
  Journal of the National Cancer Institute 2024 Lee KM, Nelson TJ, Bryant A, Teerlink CC, Gulati R, Pagadala MS, Tcheandjieu C, Pridgen KM, DuVall SL, Yamoah K, Vassy JL, Seibert TM, Hauger RL, Rose BS, Lynch JA
• Multi-Ancestry Polygenic Risk Score for Coronary Heart Disease Based on an Ancestrally Diverse Genome-Wide Association Study and Population-Specific Optimization.
  Circulation. Genomic and precision medicine 2024 Smith JL, Tcheandjieu C, Dikilitas O, Iyer K, Miyazawa K, Hilliard A, Lynch J, Rotter JI, Chen YI, Sheu WH, Chang KM, Kanoni S, Tsao PS, Ito K, Kosel M, Clarke SL, Schaid DJ, Assimes TL, Kullo IJ
• Genetic architecture distinguishes tinnitus from hearing loss.
  Nature communications 2024 Clifford RE, Maihofer AX, Chatzinakos C, Coleman JRI, Daskalakis NP, Gasperi M, Hogan K, Mikita EA, Stein MB, Tcheandjieu C, Telese F, Zuo Y, Ryan AF, Nievergelt CM
• Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification.
  Nature cardiovascular research 2023 de Vries PS, Conomos MP, Singh K, Nicholson CJ, Jain D, Hasbani NR, Jiang W, Lee S, Lino Cardenas CL, Lutz SM, Wong D, Guo X, Yao J, Young EP, Tcheandjieu C, Hilliard AT, Bis JC, Bielak LF, Brown MR, …
• Diversifying the Genetic Landscape of Heart Disease.
  JAMA 2023 Tcheandjieu C, Cappola TP
• A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease.
  Nature medicine 2023 Patel AP, Wang M, Ruan Y, Koyama S, Clarke SL, Yang X, Tcheandjieu C, Agrawal S, Fahed AC, Ellinor PT, Genes & Health Research Team; the Million Veteran Program, Tsao PS, Sun YV, Cho K, Wilson PWF…
• A Multi-Ancestry Polygenic Risk Score for Coronary Heart Disease Based on an Ancestrally Diverse Genome-Wide Association Study and Population-Specific Optimization.
  medRxiv : the preprint server for health sciences 2023 Smith JL, Tcheandjieu C, Dikilitas O, Lyer K, Miyazawa K, Hilliard A, Lynch J, Rotter JI, Chen YI, Sheu WH, Chang KM, Kanoni S, Tsao P, Ito K, Kosel M, Clarke SL, Schaid DJ, Assimes TL, Kullo IJ
• Oligogenic Architecture of Rare Noncoding Variants Distinguishes 4 Congenital Heart Disease Phenotypes.
  Circulation. Genomic and precision medicine 2023 Yu M, Aguirre M, Jia M, Gjoni K, Cordova-Palomera A, Munger C, Amgalan D, Rosa Ma X, Pereira A, Tcheandjieu C, Seidman C, Seidman J, Tristani-Firouzi M, Chung W, Goldmuntz E, Srivastava D, Loos RJF, …
• Genetic Determinants of the Interventricular Septum Are Linked to Ventricular Septal Defects and Hypertrophic Cardiomyopathy.
  Circulation. Genomic and precision medicine 2023 Yu M, Harper AR, Aguirre M, Pittman M, Tcheandjieu C, Amgalan D, Grace C, Goel A, Farrall M, Xiao K, Engreitz J, Pollard KS, Watkins H, Priest JR
• Relationship Between Ascending Thoracic Aortic Diameter and Blood Pressure: A Mendelian Randomization Study.
  Arteriosclerosis, thrombosis, and vascular biology 2023 DePaolo J, Levin MG, Tcheandjieu C, Priest JR, Gill D, Burgess S, Damrauer SM, Chirinos JA
• Genomics and phenomics of body mass index reveals a complex disease network.
  Nature communications 2022 Huang J, Huffman JE, Huang Y, Do Valle Í, Assimes TL, Raghavan S, Voight BF, Liu C, Barabási AL, Huang RDL, Hui Q, Nguyen XT, Ho YL, Djousse L, Lynch JA, Vujkovic M, Tcheandjieu C, Tang H, Damrauer SM…
• Fibromuscular Dysplasia and Abdominal Aortic Aneurysms Are Dimorphic Sex-Specific Diseases With Shared Complex Genetic Architecture.
  Circulation. Genomic and precision medicine 2022 Katz AE, Yang ML, Levin MG, Tcheandjieu C, Mathis M, Hunker K, Blackburn S, Eliason JL, Coleman DM, Fendrikova-Mahlay N, Gornik HL, Karmakar M, Hill H, Xu C, Zawistowski M, Brummett CM, Zoellner S, …
• Black In Cardio: promoting diversity and representation in the cardiovascular field.
  Nature reviews. Cardiology 2022 Amartey J, Okagbue C, Saccoh A, Buffonge S, Francois A, Tcheandjieu C, Mitchell S, Tyrrell DJ, Kamin Mukaz D
• A saturated map of common genetic variants associated with human height.
  Nature 2022 Yengo L, Vedantam S, Marouli E, Sidorenko J, Bartell E, Sakaue S, Graff M, Eliasen AU, Jiang Y, Raghavan S, Miao J, Arias JD, Graham SE, Mukamel RE, Spracklen CN, Yin X, Chen SH, Ferreira T, Highland …
• Broad clinical manifestations of polygenic risk for coronary artery disease in the Women's Health Initiative.
  Communications medicine 2022 Clarke SL, Parham M, Lankester J, Shadyab AH, Liu S, Kooperberg C, Manson JE, Tcheandjieu C, Assimes TL
• Understanding the comorbidity between posttraumatic stress severity and coronary artery disease using genome-wide information and electronic health records.
  Molecular psychiatry 2022 Polimanti R, Wendt FR, Pathak GA, Tylee DS, Tcheandjieu C, Hilliard AT, Levey DF, Adhikari K, Gaziano JM, O'Donnell CJ, Assimes TL, Stein MB, Gelernter J
• Large-scale genome-wide association study of coronary artery disease in genetically diverse populations.
  Nature medicine 2022 Tcheandjieu C, Zhu X, Hilliard AT, Clarke SL, Napolioni V, Ma S, Lee KM, Fang H, Chen F, Lu Y, Tsao NL, Raghavan S, Koyama S, Gorman BR, Vujkovic M, Klarin D, Levin MG, Sinnott-Armstrong N, Wojcik GL,…
• Race and Ethnicity Stratification for Polygenic Risk Score Analyses May Mask Disparities in Hispanics.
  Circulation 2022 Clarke SL, Huang RDL, Hilliard AT, Tcheandjieu C, Lynch J, Damrauer SM, Chang KM, Tsao PS, Assimes TL
• Use of Polygenic Risk Scores for Coronary Heart Disease in Ancestrally Diverse Populations.
  Current cardiology reports 2022 Dikilitas O, Schaid DJ, Tcheandjieu C, Clarke SL, Assimes TL, Kullo IJ
• Genetic interactions drive heterogeneity in causal variant effect sizes for gene expression and complex traits.
  American journal of human genetics 2022 Patel RA, Musharoff SA, Spence JP, Pimentel H, Tcheandjieu C, Mostafavi H, Sinnott-Armstrong N, Clarke SL, Smith CJ, V.A. Million Veteran Program, Durda PP, Taylor KD, Tracy R, Liu Y, Johnson WC, …
• A multi-population phenome-wide association study of genetically-predicted height in the Million Veteran Program.
  PLoS genetics 2022 Raghavan S, Huang J, Tcheandjieu C, Huffman JE, Litkowski E, Liu C, Ho YA, Hunter-Zinck H, Zhao H, Marouli E, North KE, VA Million Veteran Program, Lange E, Lange LA, Voight BF, Gaziano JM, Pyarajan S…
• A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation.
  Nature genetics 2022 Vujkovic M, Ramdas S, Lorenz KM, Guo X, Darlay R, Cordell HJ, He J, Gindin Y, Chung C, Myers RP, Schneider CV, Park J, Lee KM, Serper M, Carr RM, Kaplan DE, Haas ME, MacLean MT, Witschey WR, Zhu X, …
• High heritability of ascending aortic diameter and trans-ancestry prediction of thoracic aortic disease.
  Nature genetics 2022 Tcheandjieu C, Xiao K, Tejeda H, Lynch JA, Ruotsalainen S, Bellomo T, Palnati M, Judy R, Klarin D, Kember RL, Verma S, Regeneron Genetics Center, VA Million Veterans Program, FinnGen Project, Palotie …
• Genome-Wide Association Study on Carotid Intima-Media Thickness Identified New Risk Loci That Shares Genetic Risk With Cardiovascular Diseases.
  Arteriosclerosis, thrombosis, and vascular biology 2022 Tcheandjieu C
• Coronary Artery Disease Risk of Familial Hypercholesterolemia Genetic Variants Independent of Clinically Observed Longitudinal Cholesterol Exposure.
  Circulation. Genomic and precision medicine 2022 Clarke SL, Tcheandjieu C, Hilliard AT, Lee KM, Lynch J, Chang KM, Miller D, Knowles JW, O'Donnell C, Tsao PS, Rader DJ, Wilson PW, Sun YV, Gaziano JM, Assimes TL, VA Million Veteran Program
• Computational estimates of annular diameter reveal genetic determinants of mitral valve function and disease.
  JCI insight 2022 Yu M, Tcheandjieu C, Georges A, Xiao K, Tejeda H, Dina C, Le Tourneau T, Fiterau M, Judy R, Tsao NL, Amgalan D, Munger CJ, Engreitz JM, Damrauer SM, Bouatia-Naji N, Priest JR
• Genetic Loci Associated With COVID-19 Positivity and Hospitalization in White, Black, and Hispanic Veterans of the VA Million Veteran Program.
  Frontiers in genetics 2022 Peloso GM, Tcheandjieu C, McGeary JE, Posner DC, Ho YL, Zhou JJ, Hilliard AT, Joseph J, O'Donnell CJ, Efird JT, Crawford DC, Wu WC, Arjomandi M, VA Million Veteran Program COVID-19 Science Initiative,…
• The Propagation of Racial Disparities in Cardiovascular Genomics Research.
  Circulation. Genomic and precision medicine 2021 Clarke SL, Assimes TL, Tcheandjieu C
• Associations of Genetically Predicted Lp(a) (Lipoprotein [a]) Levels With Cardiovascular Traits in Individuals of European and African Ancestry.
  Circulation. Genomic and precision medicine 2021 Satterfield BA, Dikilitas O, Safarova MS, Clarke SL, Tcheandjieu C, Zhu X, Bastarache L, Larson EB, Justice AE, Shang N, Rosenthal EA, Shah AS, Namjou-Khales B, Urbina EM, Wei WQ, Feng Q, Jarvik GP, …
• Combining Clinical and Polygenic Risk Improves Stroke Prediction Among Individuals With Atrial Fibrillation.
  Circulation. Genomic and precision medicine 2021 O'Sullivan JW, Shcherbina A, Justesen JM, Turakhia M, Perez M, Wand H, Tcheandjieu C, Clarke SL, Rivas MA, Ashley EA
• Association of the transthyretin variant V122I with polyneuropathy among individuals of African ancestry.
  Scientific reports 2021 Parker MM, Damrauer SM, Tcheandjieu C, Erbe D, Aldinc E, Hawkins PN, Gillmore JD, Hull LE, Lynch JA, Joseph J, Ticau S, Flynn-Carroll AO, Deaton AM, Ward LD, Assimes TL, Tsao PS, Chang KM, Rader DJ, …
• A phenome-wide association study of 26 mendelian genes reveals phenotypic expressivity of common and rare variants within the general population.
  PLoS genetics 2020 Tcheandjieu C, Aguirre M, Gustafsson S, Saha P, Potiny P, Haendel M, Ingelsson E, Rivas MA, Priest JR
• Inherited Extremes of Aortic Diameter Confer Risk for a Specific Class of Congenital Heart Disease.
  Circulation. Genomic and precision medicine 2020 Tcheandjieu C, Zanetti D, Yu M, Priest JR
• Cardiac Imaging of Aortic Valve Area From 34 287 UK Biobank Participants Reveals Novel Genetic Associations and Shared Genetic Comorbidity With Multiple Disease Phenotypes.
  Circulation. Genomic and precision medicine 2020 Córdova-Palomera A, Tcheandjieu C, Fries JA, Varma P, Chen VS, Fiterau M, Xiao K, Tejeda H, Keavney BD, Cordell HJ, Tanigawa Y, Venkataraman G, Rivas MA, Ré C, Ashley E, Priest JR
• Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program.
  Circulation 2020 Klarin D, Verma SS, Judy R, Dikilitas O, Wolford BN, Paranjpe I, Levin MG, Pan C, Tcheandjieu C, Spin JM, Lynch J, Assimes TL, Åldstedt Nyrønning L, Mattsson E, Edwards TL, Denny J, Larson E, Lee MTM,…
• Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction.
  Nature communications 2020 Saw J, Yang ML, Trinder M, Tcheandjieu C, Xu C, Starovoytov A, Birt I, Mathis MR, Hunker KL, Schmidt EM, Jackson L, Fendrikova-Mahlay N, Zawistowski M, Brummett CM, Zoellner S, Katz A, Coleman DM, …
• Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis.
  Nature genetics 2020 Vujkovic M, Keaton JM, Lynch JA, Miller DR, Zhou J, Tcheandjieu C, Huffman JE, Assimes TL, Lorenz K, Zhu X, Hilliard AT, Judy RL, Huang J, Lee KM, Klarin D, Pyarajan S, Danesh J, Melander O, Rasheed A…
• Role of GSTM1 and GSTT1 genotypes in differentiated thyroid cancer and interaction with lifestyle factors: Results from case-control studies in France and New Caledonia.
  PloS one 2020 Tcheandjieu C, Cordina-Duverger E, Mulot C, Baron-Dubourdieu D, Guizard AV, Schvartz C, Laurent-Puig P, Guénel P, Truong T
• Highlights From the American Heart Association's EPI|LIFESTYLE 2019 Scientific Sessions.
  Journal of the American Heart Association 2019 Alonso A, Anderson MD, Bancks MP, Brown SA, Caughey MC, Chang AR, Delker E, Foti K, Gingras V, Nanna MG, Razavi AC, Scott J, Selvin E, Tcheandjieu C, Thomas AG, Turkson-Ocran RN, Webel A, Young DR, …
• Substantial Cardiovascular Morbidity in Adults With Lower-Complexity Congenital Heart Disease.
  Circulation 2019 Saha P, Potiny P, Rigdon J, Morello M, Tcheandjieu C, Romfh A, Fernandes SM, McElhinney DB, Bernstein D, Lui GK, Shaw GM, Ingelsson E, Priest JR
• Hormonal and reproductive risk factors of papillary thyroid cancer: A population-based case-control study in France.
  Cancer epidemiology 2017 Cordina-Duverger E, Leux C, Neri M, Tcheandjieu C, Guizard AV, Schvartz C, Truong T, Guénel P
• Fine-mapping of two differentiated thyroid carcinoma susceptibility loci at 9q22.33 and 14q13.3 detects novel candidate functional SNPs in Europeans from metropolitan France and Melanesians from New Caledonia.
  International journal of cancer 2016 Tcheandjieu C, Lesueur F, Sanchez M, Baron-Dubourdieu D, Guizard AV, Mulot C, Laurent-Puig P, Schvartz C, Truong T, Guenel P