Cassandra Belair, PhD
Researcher
Urology
School of Medicine

Education & Training

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• PhD Molecular and Environmental Toxicology University of Wisconsin, Madison 1997
• BS Biochemistry/Biophysics State University of New York, Plattsburgh 1990

Websites

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• Blelloch Lab (blellochlab.ucsf.edu)

Grants and Projects

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• Tcdd Resistant Zebrafish Mutants, NIH, 1999-1900

Publications (26)

Top publication keywords:
Polychlorinated DibenzodioxinsSequence Analysis, RNAHigh-Throughput Nucleotide SequencingShear StrengthHuman Embryonic Stem CellsPTEN PhosphohydrolaseMicroRNAsPlacentaZebrafishGiant CellsRNA-Binding ProteinsSpecimen HandlingReverse Transcriptase Polymerase Chain ReactionOsteocytesErythropoiesis

• Abstract LB237: PVRL2 suppresses antitumor immune responses through PVRIG- and TIGIT-independent pathways.
  Cancer Research 2024 Jiuling Yang, Li Wang, James Byrnes, Lisa Kirkemo, Hannah Driks, Cassandra Belair, Oscar Aguilar, Lewis Lanier, Jim Wells, Lawrence Fong, Robert Blelloch
• PVRL2 Suppresses Antitumor Immunity through PVRIG- and TIGIT-independent Pathways.
  Cancer immunology research 2024 Yang J, Wang L, Byrnes JR, Kirkemo LL, Driks H, Belair CD, Aguilar OA, Lanier LL, Wells JA, Fong L, Blelloch R
• MP45-05 MICRORNA 185-5P IS A NOVEL BIOMARKER ASSOCIATED WITH HIGH-RISK PATHOLOGY AT RADICAL PROSTATECTOMY IN PATIENTS WITH LOW-RISK DISEASE AT DIAGNOSIS.
  Investigative Urology 2022 Kevin Shee, Cassandra Belair, John Neuhaus, Janet Cowen, Robert Blelloch, Matthew Cooperberg
• Mechanosensitive miR-100 coordinates TGFβ and Wnt signaling in osteocytes during fluid shear stress.
  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Dole NS, Yoon J, Monteiro DA, Yang J, Mazur CM, Kaya S, Belair CD, Alliston T
• Fluid shear stress generates a unique signaling response by activating multiple TGFβ family type I receptors in osteocytes.
  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Monteiro DA, Dole NS, Campos JL, Kaya S, Schurman CA, Belair CD, Alliston T

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• LIN28B Impairs the Transition of hESC-Derived β Cells from the Juvenile to Adult State.
  Stem cell reports 2019 Zhou X, Nair GG, Russ HA, Belair CD, Li ML, Shveygert M, Hebrok M, Blelloch R
• Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory.
  Cell 2019 Poggio M, Hu T, Pai CC, Chu B, Belair CD, Chang A, Montabana E, Lang UE, Fu Q, Fong L, Blelloch R
• High-throughput, Efficient, and Unbiased Capture of Small RNAs from Low-input Samples for Sequencing.
  Scientific reports 2019 Belair CD, Hu T, Chu B, Freimer JW, Cooperberg MR, Blelloch RH
• The eutheria-specific miR-290 cluster modulates placental growth and maternal-fetal transport.
  Development (Cambridge, England) 2017 Paikari A, D Belair C, Saw D, Blelloch R
• DGCR8 is essential for tumor progression following PTEN loss in the prostate.
  EMBO reports 2015 Belair CD, Paikari A, Moltzahn F, Shenoy A, Yau C, Dall'Era M, Simko J, Benz C, Blelloch R
• miR-19, miR-345, miR-519c-5p serum levels predict adverse pathology in prostate cancer patients eligible for active surveillance.
  PloS one 2014 Wang SY, Shiboski S, Belair CD, Cooperberg MR, Simko JP, Stoppler H, Cowan J, Carroll PR, Blelloch R
• MicroRNAs to Pathways in Stem Cells and Cancer.
  The FASEB Journal 2012 Robert Blelloch, Deepa Subramanyam, Collin Melton, Robert Judson, Cassandra Belair
• PML-RAR{alpha} and Dnmt3a1 cooperate in vivo to promote acute promyelocytic leukemia.
  Cancer research 2010 Subramanyam D, Belair CD, Barry-Holson KQ, Lin H, Kogan SC, Passegué E, Blelloch R
• Construction and application of a zebrafish array comparative genomic hybridization platform.
  Genes, chromosomes & cancer 2009 Freeman JL, Ceol C, Feng H, Langenau DM, Belair C, Stern HM, Song A, Paw BH, Look AT, Zhou Y, Zon LI, Lee C
• Posttranscriptional crossregulation between Drosha and DGCR8.
  Cell 2009 Han J, Pedersen JS, Kwon SC, Belair CD, Kim YK, Yeom KH, Yang WY, Haussler D, Blelloch R, Kim VN
• Disruption of erythropoiesis by dioxin in the zebrafish.
  Developmental dynamics : an official publication of the American Association of Anatomists 2001 Belair CD, Peterson RE, Heideman W
• Telomerase Activity.
  The Journal of Urology 1998 C. D. Belair, T. R. Yeager, P. M. Lopez, C. A. Reznikoff
• Minimal deletion of 3p13-->14.2 associated with immortalization of human uroepithelial cells.
  Genes, chromosomes & cancer 1998 Vieten L, Belair CD, Savelieva L, Jülicher K, Bröcker F, Bardenheuer W, Schütte J, Opalka B, Reznikoff CA
• Telomerase activity: a biomarker of cell proliferation, not malignant transformation.
  Proceedings of the National Academy of Sciences of the United States of America 1997 Belair CD, Yeager TR, Lopez PM, Reznikoff CA
• 20q gain associates with immortalization: 20q13.2 amplification correlates with genome instability in human papillomavirus 16 E7 transformed human uroepithelial cells.
  Oncogene 1997 Savelieva E, Belair CD, Newton MA, DeVries S, Gray JW, Waldman F, Reznikoff CA
• A molecular genetic model of human bladder cancer pathogenesis.
  Seminars in oncology 1996 Reznikoff CA, Belair CD, Yeager TR, Savelieva E, Blelloch RH, Puthenveettil JA, Cuthill S
• Elevated p16 at senescence and loss of p16 at immortalization in human papillomavirus 16 E6, but not E7, transformed human uroepithelial cells.
  Cancer research 1996 Reznikoff CA, Yeager TR, Belair CD, Savelieva E, Puthenveettil JA, Stadler WM
• Increased p16 levels correlate with pRb alterations in human urothelial cells.
  Cancer research 1995 Yeager T, Stadler W, Belair C, Puthenveettil J, Olopade O, Reznikoff C
• Immortalization of human uroepithelial cells by human papillomavirus 16 E6 or E7.
  International Journal of Cancer 1995 Cassandra D. Belair, Robert H. Blelloch, Catherine A. Reznikoff
• Long-term genome stability and minimal genotypic and phenotypic alterations in HPV16 E7-, but not E6-, immortalized human uroepithelial cells.
  Genes & development 1994 Reznikoff CA, Belair C, Savelieva E, Zhai Y, Pfeifer K, Yeager T, Thompson KJ, DeVries S, Bindley C, Newton MA
• Engineering cellulase mixtures by varying the mole fraction of Thermomonospora fusca E5 and E3, Trichoderma reesei CBHI, and Caldocellum saccharolyticum beta-glucosidase.
  Biotechnology and bioengineering 1993 Walker LP, Belair CD, Wilson DB, Irwin DC