Carson Moseley, MD, PhD
Assistant Professor
Neurology
School of Medicine

Awards

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• National Institutes of Health Research in Emerging Areas Critical to Human Health LRP Award, 2024
• Weill Neurohub Award for Clinician-Scientists in the Neurosciences, 2024
• National Multiple Sclerosis Society Clinician Scientist Development Award, 2022
• Samuel Clements Little Award for Excellence in Neurology, 2018
• Max D. Cooper Endowed Immunology Travel Award, 2016
• National Institutes of Health Ruth L. Kirchstein National Research Service Award, 2013
• Howard Hughes Medical Institute (HHMI) Medical Student Research Fellow, 2011

Education & Training

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• PhD Immunology UAB
• MD Medicine UAB
• Fellowship Multiple Sclerosis & Neuroimmunology UCSF
• Residency Neurology UCSF
• BS Biology Wake Forest University

Interests

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• Multiple Sclerosis
• Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD)
• Neuroimmunology
• Neuromyelitis optica (NMO)

Publications (18)

Top publication keywords:
Central Nervous SystemAutoantibodiesMyelin-Oligodendrocyte GlycoproteinNeuromyelitis OpticaB-LymphocytesAquaporin 4Antigen PresentationOrthomyxoviridae InfectionsAutoantigensEncephalomyelitis, Autoimmune, ExperimentalSjogren's SyndromeAutoimmunityAquaporin 5Complement System ProteinsMolecular Mimicry

• Sjögren Syndrome Candidate Autoantigen AQP5 Triggers AQP4 CNS Autoimmunity Through Self-Antigen Mimicry.
  Neurology(R) neuroimmunology & neuroinflammation 2025 Moseley CE, Sagan S, Boquett JA, Spencer CM, Hollenbach JA, Sobel RA, Rothbard JB, Steinman L, Sabatino JJ, Zamvil SS
• B-cell antigen presentation in central nervous system autoimmunity.
  Current opinion in immunology 2025 Moseley CE, Sabatino JJ, Zamvil SS
• Distinct plasma lipids predict axonal injury and multiple sclerosis activity.
  Journal of neurology, neurosurgery, and psychiatry 2025 Schoeps VA, Bhargava P, Virupakshaiah A, Ladakis DC, Moseley C, Chong J, Aaen G, Graves JS, Benson L, Gorman MP, Rensel M, Abrams A, Mar S, Lotze TE, Chitnis T, Waldman A, Krupp L, Rodriguez M, …
• Predictors of a relapsing course in myelin oligodendrocyte glycoprotein antibody-associated disease.
  Journal of neurology, neurosurgery, and psychiatry 2024 Virupakshaiah A, Schoeps VA, Race J, Waltz M, Sharayah S, Nasr Z, Moseley CE, Zamvil SS, Gaudioso C, Schuette A, Casper TC, Rose J, Flanagan EP, Rodriguez M, Tillema JM, Chitnis T, Gorman MP, Graves …
• High-yield production of recombinant human myelin oligodendrocyte glycoprotein in SHuffle bacteria without a refolding step.
  Journal of immunological methods 2024 Wu W, Gupta S, Sagan SA, Moseley CE, Zamvil SS, Pak JE

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• Should We Measure CSF Complement Levels in Patients With MOGAD?
  Neurology(R) neuroimmunology & neuroinflammation 2024 Moseley CE, Zamvil SS
• MOG CNS Autoimmunity and MOGAD.
  Neurology(R) neuroimmunology & neuroinflammation 2024 Moseley CE, Virupakshaiah A, Forsthuber TG, Steinman L, Waubant E, Zamvil SS
• Life-Threatening MOG Antibody-Associated Hemorrhagic ADEM With Elevated CSF IL-6.
  Neurology(R) neuroimmunology & neuroinflammation 2024 Virupakshaiah A, Moseley CE, Elicegui S, Gerwitz LM, Spencer CM, George E, Shah M, Cree BAC, Waubant E, Zamvil SS
• Targeting PGLYRP1 in cancer and autoimmunity.
  Nature immunology 2023 Moseley CE, Zamvil SS
• T cell deletional tolerance restricts AQP4 but not MOG CNS autoimmunity.
  Proceedings of the National Academy of Sciences of the United States of America 2023 Sagan SA, Moinfar Z, Moseley CE, Dandekar R, Spencer CM, Verkman AS, Ottersen OP, Sobel RA, Sidney J, Sette A, Anderson MS, Steinman L, Wilson MR, Sabatino JJ, Zamvil SS
• Insulin-Like Growth Factors Are Key Regulators of T Helper 17 Regulatory T Cell Balance in Autoimmunity.
  Immunity 2020 DiToro D, Harbour SN, Bando JK, Benavides G, Witte S, Laufer VA, Moseley C, Singer JR, Frey B, Turner H, Bruning J, Darley-Usmar V, Gao M, Conover C, Hatton RD, Frank S, Colonna M, Weaver CT
• Reduction of AMPA receptor activity on mature oligodendrocytes attenuates loss of myelinated axons in autoimmune neuroinflammation.
  Science advances 2020 Evonuk KS, Doyle RE, Moseley CE, Thornell IM, Adler K, Bingaman AM, Bevensee MO, Weaver CT, Min B, DeSilva TM
• Batf Pioneers the Reorganization of Chromatin in Developing Effector T Cells via Ets1-Dependent Recruitment of Ctcf.
  Cell reports 2019 Pham D, Moseley CE, Gao M, Savic D, Winstead CJ, Sun M, Kee BL, Myers RM, Weaver CT, Hatton RD
• Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination.
  Journal of visualized experiments : JoVE 2016 Evonuk KS, Moseley CE, Doyle RE, Weaver CT, DeSilva TM
• T cell cytokine signatures: Biomarkers in pediatric multiple sclerosis.
  Journal of neuroimmunology 2016 Cala CM, Moseley CE, Steele C, Dowdy SM, Cutter GR, Ness JM, DeSilva TM
• Inhibition of System Xc(-) Transporter Attenuates Autoimmune Inflammatory Demyelination.
  Journal of immunology (Baltimore, Md. : 1950) 2015 Evonuk KS, Baker BJ, Doyle RE, Moseley CE, Sestero CM, Johnston BP, De Sarno P, Tang A, Gembitsky I, Hewett SJ, Weaver CT, Raman C, DeSilva TM
• Peroxisome proliferator-activated receptor and AMP-activated protein kinase agonists protect against lethal influenza virus challenge in mice.
  Influenza and other respiratory viruses 2010 Moseley CE, Webster RG, Aldridge JR
• TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection.
  Proceedings of the National Academy of Sciences of the United States of America 2009 Aldridge JR, Moseley CE, Boltz DA, Negovetich NJ, Reynolds C, Franks J, Brown SA, Doherty PC, Webster RG, Thomas PG