Carolyn Sangokoya, MD, PhD
Assistant Professor
Pathology
School of Medicine

415-476-0768

Carolyn Sangokoya, MD, PhD, is a physician-scientist, board-certified pathologist, and Assistant Professor in the Department of Pathology at University of California, San Francisco. Dr. Sangokoya's broader scientific mission is to discover and build molecular tools to re-engineer and re-wire cell fates for targeted plasticity and regenerative medicine.

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Dr. Sangokoya completed her medical and graduate training as part of the Medical Scientist Training Program at Duke University, where she discovered roles for microRNAs in oxidative stress and cellular iron homeostasis during her graduate studies with Jen-Tsan Ashley Chi in the Duke University Program in Genetics and Genomics. At UCSF, she completed her post-graduate training in Anatomic Pathology, Surgical Pathology, and Gastrointestinal/Hepatobiliary Pathology through the Department of Pathology Physician-Scientist Pathway, and postdoctoral studies in stem cell and regenerative biology with Robert Blelloch at the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, where she defined an axis of post-transcriptional control, endocytosis, and signal transduction essential for multiple aspects of stem cell biology. Dr. Sangokoya is a recipient of the K08 Career Development Award from the NIH/NICHD to decipher post-transcriptional regulation of cell fate in early mammalian development, as well as a recipient of the Burroughs Wellcome Fund Career Award for Medical Scientists.

Dr. Sangokoya’s clinical interests are primarily in human liver pathobiology and diagnostics for precision-based medicine and regenerative therapies focused on steatotic liver disease and metabolic dysfunction associated steatohepatitis (MASH, formerly NASH), a leading cause of chronic liver disease, cirrhosis, and transplantation. As a stem cell biologist, her basic science research interests are in dissecting the molecular networks that fine-tune the wiring and re-wiring of cell fates in mammalian stem cell-based models, leveraging genome engineering, quantitative cell biology, RNA sequencing, imaging, and cytometry at single-cell resolution.

Awards

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  • Chancellor Award for Advancement of Women, UCSF, 2024
  • Pilot/Feasibility Award, NIDDK/UCSF Liver Center, 2023-2025
  • Career Award for Medical Scientists, Burroughs Wellcome Fund, 2022-2027
  • ASCI Young Physician Scientist Award, American Society for Clinical Investigation, 2022
  • Session Chair, “Post-Transcriptional Gene Regulation” (2022), Gordon Research Conferences, 2022
  • Travel Award "Post-Transcriptional Gene Regulation" (2022), Gordon Research Conferences, 2022
  • John A. Watson Faculty Scholar, UCSF School of Medicine, 2021-2024
  • Program for Breakthrough Biomedical Research Postdoc Independent Research Award, UCSF, 2017
  • Eli and Edythe Broad Regeneration Medicine and Stem Cell Fellowship, UCSF, 2015-2016
  • Stowell Orbison (selected best pathology trainee abstracts), United States and Canadian Academy of Pathology, 2015
  • Stowell Orbison (selected best pathology trainee abstracts), United States and Canadian Academy of Pathology, 2014
  • Dean’s Recognition Award, outstanding performance, Duke University School of Medicine, 2012
  • Aspen Health Forum Fellow, The Aspen Institute, 2007

Education & Training

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  • Diversity, Equity, and Inclusion Champion Training University of California 2021
  • Fellowship Postdoctoral Fellow University of California, San Francisco 2021
  • Residency Anatomic Pathology University of California, San Francisco 2015
  • Fellowship Gastrointestinal and Hepatobiliary Pathology University of California, San Francisco 2015
  • Fellowship Surgical Pathology University of California, San Francisco 2015
  • MD Medical Scientist Training Program (MSTP) Duke University School of Medicine 2012
  • PhD Genetics and Genomics Duke University 2011
  • AB Human Biology (conc: Molecular Genetics) Stanford University 2003

Websites

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Grants and Projects

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Publications (8)

Top publication keywords:
Germ LayersMAP Kinase Signaling SystemIron-Regulatory ProteinsK562 CellsProfilinsPluripotent Stem CellsEndocytosisHealth Benefit Plans, EmployeeIronErythrocytesMicroRNAsCation Transport ProteinsCost SharingAnemia, Sickle CellEmbryonic Stem Cells