Caroline Escoubas, PhD, MD
Postdoctoral Scholar
Psychiatry
School of Medicine

Publications (14)

Top publication keywords:
Caloric RestrictionTranscription, GeneticSignal TransductionProtein KinasesMicrogliaCaenorhabditis elegansInterleukin-13Cathepsin BMitochondrial DynamicsBrainTrans-ActivatorsMeningesPhagocytosisLongevityInterferon Type I

• Microglial cathepsin B is necessary for neuronal efferocytosis in zebrafish and mice during brain development.
  Nature communications 2026 Silva NJ, Anderson SR, Mula SA, Escoubas CC, Nakajo H, Molofsky AV
• NOVA: a novel R-package enabling multi-parameter analysis and visualization of neural activity in MEA recordings.
  bioRxiv : the preprint server for biology 2025 Escoubas CC, Guney E, Miravet ÀT, Magee N, Phua R, Ruggero D, Molofsky AV, Weiss WA
• Microglial cathepsin B promotes neuronal efferocytosis during brain development.
  bioRxiv : the preprint server for biology 2024 Silva NJ, Anderson S, Mula SA, Escoubas CC, Nakajo H, Molofsky AV
• Group 2 innate lymphoid cells promote inhibitory synapse development and social behavior.
  Science (New York, N.Y.) 2024 Barron JJ, Mroz NM, Taloma SE, Dahlgren MW, Ortiz-Carpena JF, Keefe MG, Escoubas CC, Dorman LC, Vainchtein ID, Chiaranunt P, Kotas ME, Nowakowski TJ, Bender KJ, Molofsky AB, Molofsky AV
• Microglia as integrators of brain-associated molecular patterns.
  Trends in immunology 2024 Escoubas CC, Molofsky AV

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• Type-I-interferon-responsive microglia shape cortical development and behavior.
  Cell 2024 Escoubas CC, Dorman LC, Nguyen PT, Lagares-Linares C, Nakajo H, Anderson SR, Barron JJ, Wade SD, Cuevas B, Vainchtein ID, Silva NJ, Guajardo R, Xiao Y, Lidsky PV, Wang EY, Rivera BM, Taloma SE, Kim DK…
• Type I interferon responsive microglia shape cortical development and behavior.
  bioRxiv : the preprint server for biology 2023 Escoubas CC, Dorman LC, Nguyen PT, Lagares-Linares C, Nakajo H, Anderson SR, Cuevas B, Vainchtein ID, Silva NJ, Xiao Y, Lidsky PV, Wang EY, Taloma SE, Nakao-Inoue H, Schwer B, Andino R, Nowakowski TJ,…
• Group 2 innate lymphoid cells promote inhibitory synapse development and social behavior.
  bioRxiv : the preprint server for biology 2023 Barron JJ, Mroz NM, Taloma SE, Dahlgren MW, Ortiz-Carpena J, Dorman LC, Vainchtein ID, Escoubas CC, Molofsky AB, Molofsky AV
• Neuronal TORC1 modulates longevity via AMPK and cell nonautonomous regulation of mitochondrial dynamics in C. elegans.
  eLife 2019 Zhang Y, Lanjuin A, Chowdhury SR, Mistry M, Silva-García CG, Weir HJ, Lee CL, Escoubas CC, Tabakovic E, Mair WB
• Deregulation of CRTCs in Aging and Age-Related Disease Risk: (Trends in Genetics, 33, 303-321, 2017).
  Trends in genetics : TIG 2018 Escoubas CC, Silva-García CG, Mair WB
• Dietary Restriction and AMPK Increase Lifespan via Mitochondrial Network and Peroxisome Remodeling.
  Cell metabolism 2017 Weir HJ, Yao P, Huynh FK, Escoubas CC, Goncalves RL, Burkewitz K, Laboy R, Hirschey MD, Mair WB
• Corrigendum: Splicing factor 1 modulates dietary restriction and TORC1 pathway longevity in C. elegans.
  Nature 2017 Heintz C, Doktor TK, Lanjuin A, Escoubas CC, Zhang Y, Weir HJ, Dutta S, Silva-García CG, Bruun GH, Morantte I, Hoxhaj G, Manning BD, Andresen BS, Mair WB
• Deregulation of CRTCs in Aging and Age-Related Disease Risk.
  Trends in genetics : TIG 2017 Escoubas CC, Silva-García CG, Mair WB
• Splicing factor 1 modulates dietary restriction and TORC1 pathway longevity in C. elegans.
  Nature 2016 Heintz C, Doktor TK, Lanjuin A, Escoubas C, Zhang Y, Weir HJ, Dutta S, Silva-García CG, Bruun GH, Morantte I, Hoxhaj G, Manning BD, Andresen BS, Mair WB