Carlin Long, MD
Professor
Medicine
School of Medicine
My basic research interests are on the cell-specific responses to myocardial injury with a particular focus on understanding the role of pro-inflammatory molecules in the transition from compensated to decompensated myocardial failure.
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For nearly 25 years I have been investigating how cells in the heart “speak” to one another in normal and abnormal growth with a particular interest on the cardiac fibroblasts which initiate the process of scarring within the heart muscle following injury.
My clinical interests are in the arena of risk reduction for patients without known disease (primary prevention) but also in those with established disease (secondary prevention). I am particularly interested in how to engage patients in self-care using the wide variety of apps and wearables which allow for the accumulation of physiologic data over time and in monitoring how these can be modified by both behavioral cues but also in observing the response to therapies in their daily routines. In addition the advent of genome sequence data opens up another area for study in the field of prevention as well as in the patient-specific response to therapy, so-called personalized medicine.
Education & Training
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- Cardiology University of California, San Francisco 6/1989
- Chief Resident Internal Medicine University of California, San Francisco 06/1986
- Internal Medicine University of California, San Francisco 06/1985
- MD Medicine Southwestern Medical School 06/1982
- BS Biology Baylor University 06/1978
Grants and Projects
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- Post Graduate Studies in Cardiovascular Research, NIH, 1996-2024
- The Role of Histone Deacytelases in Right Ventricular Adaptation in Hypoplastic L, NIH, 2013-2015
- Cytokine modulation of the cardiac fibroblast phenotype, NIH, 1997-2007
- Small Animal Ultrasound Imager - Vevo 770, NIH, 2006-2007
- Cytokine Expression in Human &Experimental Heart Failur, NIH, 2001-2006
- Il1Beta Inhibits Cardiomyocyte Specific Gene Expression, NIH, 1998-2003
Publications (102)
Top publication keywords:
Histone Deacetylase InhibitorsHypertrophyGenes, fosMyocardiumInterleukin-1CardiomegalyMyofibroblastsVentricular RemodelingLamin Type AMyocytes, CardiacVascular StiffnessHeart FailureFatty Acids, Omega-3Histone DeacetylasesFibroblasts
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Association of SARS-CoV-2 Infection and Cardiopulmonary Long COVID With Exercise Capacity and Chronotropic Incompetence Among People With HIV.
Journal of the American Heart Association 2023 Durstenfeld MS, Peluso MJ, Spinelli MA, Li D, Hoh R, Chenna A, Yee B, Winslow J, Petropoulos C, Gandhi M, Henrich TJ, Aras MA, Long CS, Deeks SG, Hsue PY -
Reduced Exercise Capacity, Chronotropic Incompetence, and Early Systemic Inflammation in Cardiopulmonary Phenotype Long Coronavirus Disease 2019.
The Journal of infectious diseases 2023 Durstenfeld MS, Peluso MJ, Kaveti P, Hill C, Li D, Sander E, Swaminathan S, Arechiga VM, Lu S, Goldberg SA, Hoh R, Chenna A, Yee BC, Winslow JW, Petropoulos CJ, Kelly JD, Glidden DV, Henrich TJ, … -
Association of SARS-CoV-2 Infection and Cardiopulmonary Long COVID with Exercise Capacity and Chronotropic Incompetence among People with HIV.
medRxiv : the preprint server for health sciences 2023 Durstenfeld MS, Peluso MJ, Spinelli MA, Li D, Hoh R, Gandhi M, Henrich TJ, Aras MA, Long CS, Deeks SG, Hsue PY -
Reduced exercise capacity, chronotropic incompetence, and early systemic inflammation in cardiopulmonary phenotype Long COVID.
medRxiv : the preprint server for health sciences 2023 Durstenfeld MS, Peluso MJ, Kaveti P, Hill C, Li D, Sander E, Swaminathan S, Arechiga VM, Lu S, Goldberg SA, Hoh R, Chenna A, Yee BC, Winslow JW, Petropoulos CJ, Kelly JD, Glidden DV, Henrich TJ, … -
Use of Cardiopulmonary Exercise Testing to Evaluate Long COVID-19 Symptoms in Adults: A Systematic Review and Meta-analysis.
JAMA network open 2022 Durstenfeld MS, Sun K, Tahir P, Peluso MJ, Deeks SG, Aras MA, Grandis DJ, Long CS, Beatty A, Hsue PY
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Hospitalized Patients With COVID-19 Have Higher Plasma Aldosterone-Renin Ratio and Lower ACE Activity Than Controls.
Journal of the Endocrine Society 2022 Parikh NI, Arowolo F, Durstenfeld MS, Nah G, Njoroge J, Vittinghoff E, Long CS, Ganz P, Pearce D, Hsue P, Wu AHS, Hajizadeh N, Liu KD, Lynch KL -
Piezo1 Channel as a Potential Target for Hindering Cardiac Fibrotic Remodeling.
International journal of molecular sciences 2022 Braidotti N, Chen SN, Long CS, Cojoc D, Sbaizero O -
Cardiopulmonary exercise testing to evaluate post-acute sequelae of COVID-19 ("Long COVID"): a systematic review and meta-analysis.
medRxiv : the preprint server for health sciences 2022 Durstenfeld MS, Sun K, Tahir PM, Peluso MJ, Deeks SG, Aras MA, Grandis DJ, Long CS, Beatty A, Hsue PY -
Altered microtubule structure, hemichannel localization and beating activity in cardiomyocytes expressing pathologic nuclear lamin A/C.
Heliyon 2020 Borin D, Peña B, Chen SN, Long CS, Taylor MRG, Mestroni L, Sbaizero O -
Obstructive Sleep Apnea in Cardiovascular Disease: A Review of the Literature and Proposed Multidisciplinary Clinical Management Strategy.
Journal of the American Heart Association 2019 Tietjens JR, Claman D, Kezirian EJ, De Marco T, Mirzayan A, Sadroonri B, Goldberg AN, Long C, Gerstenfeld EP, Yeghiazarians Y -
3D Carbon-Nanotube-Based Composites for Cardiac Tissue Engineering.
ACS applied bio materials 2018 Martinelli V, Bosi S, Peña B, Baj G, Long CS, Sbaizero O, Giacca M, Prato M, Mestroni L -
Contrast-Enhanced Stress Echocardiography and Myocardial Perfusion Imaging in Patients Hospitalized With Chest Pain: A Randomized Study.
Critical pathways in cardiology 2018 Salame G, Juselius WE, Burden M, Long CS, Bendelow T, Beaty B, Masoudi FA, Krantz MJ -
Biomechanical defects and rescue of cardiomyocytes expressing pathologic nuclear lamins.
Cardiovascular research 2018 Laurini E, Martinelli V, Lanzicher T, Puzzi L, Borin D, Chen SN, Long CS, Lee P, Mestroni L, Taylor MRG, Sbaizero O, Pricl S -
Lung Vascular Remodeling, Cardiac Hypertrophy, and Inflammatory Cytokines in SHIVnef-Infected Macaques.
Viral immunology 2017 Almodovar S, Swanson J, Giavedoni LD, Kanthaswamy S, Long CS, Voelkel NF, Edwards MG, Folkvord JM, Connick E, Westmoreland SV, Luciw PA, Flores SC -
Use of Wavelet Transform to Detect Compensated and Decompensated Stages in the Congestive Heart Failure Patient.
Biosensors 2017 Sharma P, Newman K, Long CS, Gasiewski AJ, Barnes F -
Injectable Carbon Nanotube-Functionalized Reverse Thermal Gel Promotes Cardiomyocytes Survival and Maturation.
ACS applied materials & interfaces 2017 Peña B, Bosi S, Aguado BA, Borin D, Farnsworth NL, Dobrinskikh E, Rowland TJ, Martinelli V, Jeong M, Taylor MRG, Long CS, Shandas R, Sbaizero O, Prato M, Anseth KS, Park D, Mestroni L -
Histone deacetylase adaptation in single ventricle heart disease and a young animal model of right ventricular hypertrophy.
Pediatric research 2017 Blakeslee WW, Demos-Davies KM, Lemon DD, Lutter KM, Cavasin MA, Payne S, Nunley K, Long CS, McKinsey TA, Miyamoto SD -
The cell-stretcher: A novel device for the mechanical stimulation of cell populations.
The Review of scientific instruments 2016 Seriani S, Del Favero G, Mahaffey J, Marko D, Gallina P, Long CS, Mestroni L, Sbaizero O -
Biomimetic Polymers for Cardiac Tissue Engineering.
Biomacromolecules 2016 Peña B, Martinelli V, Jeong M, Bosi S, Lapasin R, Taylor MR, Long CS, Shandas R, Park D, Mestroni L -
Longitudinal Changes in Vascular Risk Markers and Mortality Rates among a Latino Population with Hypertension.
Texas Heart Institute journal 2016 Pflederer MC, Long CS, Beaty B, Havranek EP, Mehler PS, Keniston A, Krantz MJ -
Associations of Adiponectin with Adiposity, Insulin Sensitivity, and Diet in Young, Healthy, Mexican Americans and Non-Latino White Adults.
International journal of environmental research and public health 2015 Pereira RI, Low Wang CC, Wolfe P, Havranek EP, Long CS, Bessesen DH -
Effects of omega-3 fatty acids on arterial stiffness in patients with hypertension: a randomized pilot study.
Journal of negative results in biomedicine 2015 Krantz MJ, Havranek EP, Pereira RI, Beaty B, Mehler PS, Long CS -
The Cardiomyopathy Lamin A/C D192G Mutation Disrupts Whole-Cell Biomechanics in Cardiomyocytes as Measured by Atomic Force Microscopy Loading-Unloading Curve Analysis.
Scientific reports 2015 Lanzicher T, Martinelli V, Puzzi L, Del Favero G, Codan B, Long CS, Mestroni L, Taylor MR, Sbaizero O -
AFM single-cell force spectroscopy links altered nuclear and cytoskeletal mechanics to defective cell adhesion in cardiac myocytes with a nuclear lamin mutation.
Nucleus (Austin, Tex.) 2015 Lanzicher T, Martinelli V, Long CS, Del Favero G, Puzzi L, Borelli M, Mestroni L, Taylor MR, Sbaizero O -
Analysis of long- and short-range contribution to adhesion work in cardiac fibroblasts: an atomic force microscopy study.
Materials science & engineering. C, Materials for biological applications 2014 Sbaizero O, DelFavero G, Martinelli V, Long CS, Mestroni L -
Laser vibrometer measurement of guided wave modes in rail track.
Ultrasonics 2014 Loveday PW, Long CS -
Exploring the elasticity and adhesion behavior of cardiac fibroblasts by atomic force microscopy indentation.
Materials science & engineering. C, Materials for biological applications 2014 Codan B, Del Favero G, Martinelli V, Long CS, Mestroni L, Sbaizero O -
Targeting cardiac fibroblasts to treat fibrosis of the heart: focus on HDACs.
Journal of molecular and cellular cardiology 2014 Schuetze KB, McKinsey TA, Long CS -
Effect of class IV laser therapy on chemotherapy-induced oral mucositis: a clinical and experimental study.
The American journal of pathology 2013 Ottaviani G, Gobbo M, Sturnega M, Martinelli V, Mano M, Zanconati F, Bussani R, Perinetti G, Long CS, Di Lenarda R, Giacca M, Biasotto M, Zacchigna S -
Carbon nanotubes instruct physiological growth and functionally mature syncytia: nongenetic engineering of cardiac myocytes.
ACS nano 2013 Martinelli V, Cellot G, Toma FM, Long CS, Caldwell JH, Zentilin L, Giacca M, Turco A, Prato M, Ballerini L, Mestroni L -
MAP kinase kinase kinase-2 (MEKK2) regulates hypertrophic remodeling of the right ventricle in hypoxia-induced pulmonary hypertension.
American journal of physiology. Heart and circulatory physiology 2012 Brown RD, Ambler SK, Li M, Sullivan TM, Henry LN, Crossno JT, Long CS, Garrington TP, Stenmark KR -
Carbon nanotubes promote growth and spontaneous electrical activity in cultured cardiac myocytes.
Nano letters 2012 Martinelli V, Cellot G, Toma FM, Long CS, Caldwell JH, Zentilin L, Giacca M, Turco A, Prato M, Ballerini L, Mestroni L -
Factors influencing QT prolongation in patients hospitalized with severe anorexia nervosa.
General hospital psychiatry 2011 Krantz MJ, Sabel AL, Sagar U, Long CS, Barbey JT, White KV, Gaudiani JL, Mehler PS -
Regulatory T cells limit vascular endothelial injury and prevent pulmonary hypertension.
Circulation research 2011 Tamosiuniene R, Tian W, Dhillon G, Wang L, Sung YK, Gera L, Patterson AJ, Agrawal R, Rabinovitch M, Ambler K, Long CS, Voelkel NF, Nicolls MR -
Circulating adiponectin levels are lower in Latino versus non-Latino white patients at risk for cardiovascular disease, independent of adiposity measures.
BMC endocrine disorders 2011 Pereira RI, Wang CC, Hosokawa P, Dickinson LM, Chonchol M, Krantz MJ, Steiner JF, Bessesen DH, Havranek EP, Long CS -
Complement C3 serum levels in anorexia nervosa: a potential biomarker for the severity of disease?
Annals of general psychiatry 2011 Flierl MA, Gaudiani JL, Sabel AL, Long CS, Stahel PF, Mehler PS -
Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension.
Journal of molecular and cellular cardiology 2011 Lemon DD, Horn TR, Cavasin MA, Jeong MY, Haubold KW, Long CS, Irwin DC, McCune SA, Chung E, Leinwand LA, McKinsey TA -
Pulse wave velocity and carotid atherosclerosis in white and Latino patients with hypertension.
BMC cardiovascular disorders 2011 Krantz MJ, Long CS, Hosokawa P, Karimkahani E, Dickinson M, Estacio RO, Masoudi FA, Havranek EP -
Congestive Heart Failure home monitoring pilot study in urban Denver.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 2011 Bakhshi S, Li X, Semenov N, Apodaca-Madrid J, Mahoor MH, Newman KE, Long CS, Neuman C -
Critical role for death-receptor mediated apoptotic signaling in viral myocarditis.
Journal of cardiac failure 2010 DeBiasi RL, Robinson BA, Leser JS, Brown RD, Long CS, Clarke P -
AFos inhibits phenylephrine-mediated contractile dysfunction by altering phospholamban phosphorylation.
American journal of physiology. Heart and circulatory physiology 2010 Jeong MY, Walker JS, Brown RD, Moore RL, Vinson CS, Colucci WS, Long CS -
Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure.
Circulation 2009 Bogaard HJ, Natarajan R, Henderson SC, Long CS, Kraskauskas D, Smithson L, Ockaili R, McCord JM, Voelkel NF -
Cardiac cell-specific apoptotic and cytokine responses to reovirus infection: determinants of myocarditic phenotype.
Journal of cardiac failure 2009 Miyamoto SD, Brown RD, Robinson BA, Tyler KL, Long CS, Debiasi RL -
Prolonged administration of a dithiol antioxidant protects against ventricular remodeling due to ischemia-reperfusion in mice.
American journal of physiology. Heart and circulatory physiology 2008 Ambler SK, Hodges YK, Jones GM, Long CS, Horwitz LD -
Inpatient initiation of beta-blockade plus nurse management in vulnerable heart failure patients: a randomized study.
Journal of cardiac failure 2008 Krantz MJ, Havranek EP, Haynes DK, Smith I, Bucher-Bartelson B, Long CS -
Cytokines regulate matrix metalloproteinases and migration in cardiac fibroblasts.
Biochemical and biophysical research communications 2007 Brown RD, Jones GM, Laird RE, Hudson P, Long CS -
Comprehensive coronary artery disease care in a safety-net hospital: results of Get With The Guidelines quality improvement initiative.
Journal of managed care pharmacy : JMCP 2007 Krantz MJ, Baker WA, Estacio RO, Haynes DK, Mehler PS, Fonarow GC, Long CS -
Restoration of CREB function is linked to completion and stabilization of adaptive cardiac hypertrophy in response to exercise.
American journal of physiology. Heart and circulatory physiology 2007 Watson PA, Reusch JE, McCune SA, Leinwand LA, Luckey SW, Konhilas JP, Brown DA, Chicco AJ, Sparagna GC, Long CS, Moore RL -
Prevalence of desmin mutations in dilated cardiomyopathy.
Circulation 2007 Taylor MR, Slavov D, Ku L, Di Lenarda A, Sinagra G, Carniel E, Haubold K, Boucek MM, Ferguson D, Graw SL, Zhu X, Cavanaugh J, Sucharov CC, Long CS, Bristow MR, Lavori P, Mestroni L, Familial … -
IL-1beta stimulates rat cardiac fibroblast migration via MAP kinase pathways.
American journal of physiology. Heart and circulatory physiology 2006 Mitchell MD, Laird RE, Brown RD, Long CS -
Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure.
Circulation 2006 Voelkel NF, Quaife RA, Leinwand LA, Barst RJ, McGoon MD, Meldrum DR, Dupuis J, Long CS, Rubin LJ, Smart FW, Suzuki YJ, Gladwin M, Denholm EM, Gail DB, National Heart, Lung, and Blood Institute Working… -
The PPAR-alpha activator fenofibrate fails to provide myocardial protection in ischemia and reperfusion in pigs.
American journal of physiology. Heart and circulatory physiology 2005 Xu Y, Lu L, Greyson C, Rizeq M, Nunley K, Wyatt B, Bristow MR, Long CS, Schwartz GG -
Off-site percutaneous coronary intervention reduces hospital length of stay in vulnerable patients with acute myocardial infarction.
Critical pathways in cardiology 2005 Krantz MJ, Haugen SJ, Batal H, Long CS -
Thyroid hormone induces cardiac myocyte hypertrophy in a thyroid hormone receptor alpha1-specific manner that requires TAK1 and p38 mitogen-activated protein kinase.
Molecular endocrinology (Baltimore, Md.) 2005 Kinugawa K, Jeong MY, Bristow MR, Long CS -
AFos dissociates cardiac myocyte hypertrophy and expression of the pathological gene program.
Circulation 2005 Jeong MY, Kinugawa K, Vinson C, Long CS -
Yin Yang 1 represses alpha-myosin heavy chain gene expression in pathologic cardiac hypertrophy.
Biochemical and biophysical research communications 2005 Mariner PD, Luckey SW, Long CS, Sucharov CC, Leinwand LA -
The cardiac fibroblast: therapeutic target in myocardial remodeling and failure.
Annual review of pharmacology and toxicology 2005 Brown RD, Ambler SK, Mitchell MD, Long CS -
PPAR-gamma activation fails to provide myocardial protection in ischemia and reperfusion in pigs.
American journal of physiology. Heart and circulatory physiology 2004 Xu Y, Gen M, Lu L, Fox J, Weiss SO, Brown RD, Perlov D, Ahmad H, Zhu P, Greyson C, Long CS, Schwartz GG -
Impact of a cardiac risk reduction program in vulnerable patients hospitalized with coronary artery disease.
Pharmacotherapy 2004 Krantz MJ, Havranek EP, Mehler PS, Haynes DK, Long CS -
Deleterious effects of acute treatment with a peroxisome proliferator-activated receptor-gamma activator in myocardial ischemia and reperfusion in pigs.
Diabetes 2003 Xu Y, Lu L, Greyson C, Lee J, Gen M, Kinugawa K, Long CS, Schwartz GG -
The cardiac fibroblast, another therapeutic target for mending the broken heart?
Journal of molecular and cellular cardiology 2002 Long CS, Brown RD -
Cardiotrophin-1 in heart failure.
Circulation 2002 Bristow MR, Long CS -
Expression of TR isoforms in failing human heart.
The Journal of clinical endocrinology and metabolism 2001 Kinugawa K, Long CS, Bristow MR -
Regulation of thyroid hormone receptor isoforms in physiological and pathological cardiac hypertrophy.
Circulation research 2001 Kinugawa K, Yonekura K, Ribeiro RC, Eto Y, Aoyagi T, Baxter JD, Camacho SA, Bristow MR, Long CS, Simpson PC -
A role for the extracellular signal-regulated kinase and p38 mitogen-activated protein kinases in interleukin-1 beta-stimulated delayed signal tranducer and activator of transcription 3 activation, atrial natriuretic factor expression, and cardiac myocyte morphology.
The Journal of biological chemistry 2001 Ng DC, Long CS, Bogoyevitch MA -
The role of interleukin-1 in the failing heart.
Heart failure reviews 2001 Long CS -
Signaling pathways responsible for fetal gene induction in the failing human heart: evidence for altered thyroid hormone receptor gene expression.
Circulation 2001 Kinugawa K, Minobe WA, Wood WM, Ridgway EC, Baxter JD, Ribeiro RC, Tawadrous MF, Lowes BA, Long CS, Bristow MR -
The Ultraviolet Index: a useful tool.
Dermatology online journal 2000 Kinney JP, Long CS -
IL-1 beta increases abundance and activity of the negative transcriptional regulator yin yang-1 (YY1) in neonatal rat cardiac myocytes.
Journal of molecular and cellular cardiology 2000 Patten M, Wang W, Aminololama-Shakeri S, Burson M, Long CS -
Hypoxia differentially regulates stress proteins in cultured cardiomyocytes: role of the p38 stress-activated kinase signaling cascade, and relation to cytoprotection.
Cardiovascular research 2000 Kacimi R, Chentoufi J, Honbo N, Long CS, Karliner JS -
Pro-inflammatory cytokines stimulate mitogen-activated protein kinase subfamilies, increase phosphorylation of c-Jun and ATF2 and upregulate c-Jun protein in neonatal rat ventricular myocytes.
Journal of molecular and cellular cardiology 1999 Clerk A, Harrison JG, Long CS, Sugden PH -
Expression of skeletal muscle sarcoplasmic reticulum calcium-ATPase is reduced in rats with postinfarction heart failure.
Heart (British Cardiac Society) 1999 Simonini A, Chang K, Yue P, Long CS, Massie BM -
Angiotensin II stimulates cardiac myocyte hypertrophy via paracrine release of TGF-beta 1 and endothelin-1 from fibroblasts.
Cardiovascular research 1998 Gray MO, Long CS, Kalinyak JE, Li HT, Karliner JS -
Cardiac fibroblasts arrest at the G1/S restriction point in response to interleukin (IL)-1beta. Evidence for IL-1beta-induced hypophosphorylation of the retinoblastoma protein.
The Journal of biological chemistry 1998 Koudssi F, López JE, Villegas S, Long CS -
Post-infarction heart failure in the rat is associated with distinct alterations in cardiac myocyte molecular phenotype.
Journal of molecular and cellular cardiology 1998 Yue P, Long CS, Austin R, Chang KC, Simpson PC, Massie BM -
Cytokine expression increases in nonmyocytes from rats with postinfarction heart failure.
The American journal of physiology 1998 Yue P, Massie BM, Simpson PC, Long CS -
Expression and regulation of adhesion molecules in cardiac cells by cytokines: response to acute hypoxia.
Circulation research 1998 Kacimi R, Karliner JS, Koudssi F, Long CS -
Chronic hypoxia modulates the interleukin-1beta-stimulated inducible nitric oxide synthase pathway in cardiac myocytes.
Circulation 1997 Kacimi R, Long CS, Karliner JS -
Cross talk between angiotensin AT1 and alpha 1-adrenergic receptors: angiotensin II downregulates alpha 1a-adrenergic receptor subtype mRNA and density in neonatal rat cardiac myocytes.
Circulation research 1997 Li HT, Long CS, Gray MO, Rokosh DG, Honbo NY, Karliner JS -
Autocrine and Paracrine Regulation of Myocardial Cell Growth in Vitro The TGFβ Paradigm.
Trends in cardiovascular medicine 1996 Long CS -
Interleukin-1beta is a negative transcriptional regulator of alpha1-adrenergic induced gene expression in cultured cardiac myocytes.
The Journal of biological chemistry 1996 Patten M, Hartogensis WE, Long CS -
Alterations in skeletal muscle gene expression in the rat with chronic congestive heart failure.
Journal of molecular and cellular cardiology 1996 Simonini A, Massie BM, Long CS, Qi M, Samarel AM -
Heart failure in rats causes changes in skeletal muscle morphology and gene expression that are not explained by reduced activity.
Circulation research 1996 Simonini A, Long CS, Dudley GA, Yue P, McElhinny J, Massie BM -
Alpha1-adrenergic receptor subtype mRNAs are differentially regulated by alpha1-adrenergic and other hypertrophic stimuli in cardiac myocytes in culture and in vivo. Repression of alpha1B and alpha1D but induction of alpha1C.
The Journal of biological chemistry 1996 Rokosh DG, Stewart AF, Chang KC, Bailey BA, Karliner JS, Camacho SA, Long CS, Simpson PC -
Chronic hypoxia differentially regulates alpha 1-adrenergic receptor subtype mRNAs and inhibits alpha 1-adrenergic receptor-stimulated cardiac hypertrophy and signaling.
Circulation 1995 Li HT, Long CS, Rokosh DG, Honbo NY, Karliner JS -
Interleukin-1 beta induces cardiac myocyte growth but inhibits cardiac fibroblast proliferation in culture.
The Journal of clinical investigation 1995 Palmer JN, Hartogensis WE, Patten M, Fortuin FD, Long CS -
Cloning of the rat alpha 1C-adrenergic receptor from cardiac myocytes. alpha 1C, alpha 1B, and alpha 1D mRNAs are present in cardiac myocytes but not in cardiac fibroblasts.
Circulation research 1994 Stewart AF, Rokosh DG, Bailey BA, Karns LR, Chang KC, Long CS, Kariya K, Simpson PC -
Neutral endopeptidase in the heart. Neutral endopeptidase inhibition prevents isoproterenol-induced myocardial hypoperfusion in rats by reducing bradykinin degradation.
Circulation research 1994 Piedimonte G, Nadel JA, Long CS, Hoffman JI -
Distribution of alpha 1C-adrenergic receptor mRNA in adult rat tissues by RNase protection assay and comparison with alpha 1B and alpha 1D.
Biochemical and biophysical research communications 1994 Rokosh DG, Bailey BA, Stewart AF, Karns LR, Long CS, Simpson PC -
Beta-adrenergic stimulation of cardiac non-myocytes augments the growth-promoting activity of non-myocyte conditioned medium.
Journal of molecular and cellular cardiology 1993 Long CS, Hartogensis WE, Simpson PC -
Sympathetic modulation of the cardiac myocyte phenotype: studies with a cell-culture model of myocardial hypertrophy.
Basic research in cardiology 1992 Long CS, Kariya K, Karns L, Simpson PC -
A growth factor for cardiac myocytes is produced by cardiac nonmyocytes.
Cell regulation 1991 Long CS, Henrich CJ, Simpson PC -
Adrenergic hormones and control of cardiac myocyte growth.
Molecular and cellular biochemistry 1991 Simpson PC, Kariya K, Karns LR, Long CS, Karliner JS -
Sympathetic activity: modulator of myocardial hypertrophy.
Journal of cardiovascular pharmacology 1991 Long CS, Kariya K, Karns L, Simpson PC -
Trophic factors for cardiac myocytes.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1990 Long CS, Kariya K, Karns L, Simpson PC -
Transcription of early developmental isogenes in cardiac myocyte hypertrophy.
Journal of molecular and cellular cardiology 1989 Simpson PC, Long CS, Waspe LE, Henrich CJ, Ordahl CP -
Alpha 1-adrenergic receptor stimulation of sarcomeric actin isogene transcription in hypertrophy of cultured rat heart muscle cells.
The Journal of clinical investigation 1989 Long CS, Ordahl CP, Simpson PC -
Transcriptional repression of an embryo-specific muscle gene.
Developmental biology 1988 Long CS, Ordahl CP -
L'infarctus du ventricule droit--right ventricular infarction in the 1980s.
The Western journal of medicine 1987 Long CS -
Perioperative nursing. A special project.
AORN journal 1984 Barness SK, Long CS -
Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Demonstration of the presence of malonyl-CoA in non-hepatic tissues of the rat.
The Biochemical journal 1983 McGarry JD, Mills SE, Long CS, Foster DW -
Kinetics of carnitine-dependent fatty acid oxidation: implications for human carnitine deficiency.
Neurology 1982 Long CS, Haller RG, Foster DW, McGarry JD