Bryan Greenhouse, MD, MA
Professor
Medicine
School of Medicine
bryan.greenhouse@ucsf.edu 628-206-8844
My research is focused on developing new tools to better measure malaria transmission and determine how some people are able to be infected with malaria parasites without becoming sick. We do this by studying malaria in its natural environment, applying novel laboratory and analytical methods to high quality field studies. Most of our work is based in malaria endemic areas, primarily sub-Saharan Africa.
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My current projects focus on understanding the development of naturally acquired immunity, creating novel antibody-based tools to measure malaria exposure and immunologic protection, working on improved diagnostics, and using parasite genetics and spatial data to understand parasite transmission and evolution. I am dedicated to teaching and mentoring, and am coordinating efforts to democratize access to malaria genomics by improving access to analytics and creating training resources. Our group is also committed to improving capacity for laboratory genomics and data analysis and are actively working with several partners on these efforts. My lab is based at Zuckerberg San Francisco General Hospital, where I co-lead the UCSF EPPIcenter.
Education & Training
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- Diversity, Equity, and Inclusion Champion Training University of California 2019
- MA Biostatistics University of California, Berkeley 2009
- Fellowship Infectious Diseases University of California, San Francisco 2007
- Residency Internal Medicine Hospital of the University of Pennsylvania 2004
- MD School of Medicine University of Pennsylvania 2001
- BA Biology Williams College 1996
Websites
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- EPPIcenter: Our Research Program (eppicenter.ucsf.edu)
- PlasmoGenEpi (collaborative network I co-lead) (plasmogenepi.org)
Grants and Projects
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- Drivers of strain-specific and strain-transcendent antimalarial immunity in childhood, NIH, 2020-2025
- Computational models of naturally acquired immunity to falciparum malaria, NIH, 2020-2025
- Mentoring translational scientists in international infectious disease research, NIH, 2019-2023
- Novel serologic assays of P. falciparum exposure for improved surveillance in control and elimination., NIH, 2016-2022
- Plasmodium Falciparum Infection and Interference with Effective B Cell Memory, NIH, 2014-2017
- Translational Studies of Plasmodium Falciparum Infection Dynamics, NIH, 2008-2013
Publications (239)
Top publication keywords:
InsecticidesPlasmodiumUgandaAntibodies, ProtozoanMosquito ControlMalariaAntimalarialsParasitemiaDNA, ProtozoanPlasmodium falciparumNucleic Acid Amplification TechniquesAntigens, ProtozoanCommunicable Diseases, ImportedProtozoan ProteinsMalaria, Falciparum
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Sensitive and modular amplicon sequencing of Plasmodium falciparum diversity and resistance for research and public health.
bioRxiv : the preprint server for biology 2025 Aranda-Díaz A, Vickers EN, Murie K, Palmer B, Hathaway N, Gerlovina I, Boene S, Garcia-Ulloa M, Cisteró P, Katairo T, Semakuba FD, Nsengimaana B, Gwarinda H, García-Fernández C, Louie W, Esayas E, … -
Targeting malaria in high-risk populations in low endemic regions in northern Namibia: a quasi-experimental controlled trial to reduce malaria in seasonal agricultural workers and cattle herders.
BMJ global health 2025 Smith JL, Ntuku H, Rerolle F, Burke AM, Mwema T, Turcios K, Uusiku P, Haikali JK, Lifasi M, Smith-Gueye C, Vajda E, Jacobson JO, Greenhouse B, Gosling R, Bennett A, Mumbengegwi DR -
Relating household entomological measures to individual malaria risk.
Research square 2025 McClure M, Arinaitwe E, Kamya MR, Rosenthal PJ, Nankabirwa J, Maxwell K, Musiime A, Dorsey G, Greenhouse B, Rodriguez-Barraquer I -
Performance of Molecular Inversion Probe DR23K and Paragon MAD4HatTeR Amplicon Sequencing Panels for Detection of Plasmodium falciparum Mutations Associated with Antimalarial Drug Resistance.
Research square 2025 Katairo T, Asua V, Nsengimaana B, Tukwasibwe S, Semakuba FD, Wiringilimaana I, Garg S, Kiyaga S, Mbabazi M, Kabbale KD, Ayitewala A, Nsobya SL, Kamya MR, Ssewanyana I, Bailey JA, Aranda-Díaz A, … -
Molecular surveillance of Plasmodium falciparum histidine-rich protein 2/3 gene deletions in Mozambique, 2023.
Malaria journal 2024 da Silva C, Tembisse D, Cisteró P, Rovira-Vallbona E, Canana N, da Costa P, Matambisso G, Aranda-Díaz A, Mbeve H, Ndimande N, Timana A, Hunguana A, Boene S, Pujol A, Rafael B, Greenhouse B, Enosse S, …
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Seroprevalence of SARS-CoV-2 and risk factors for infection among children in Uganda: A serial cross-sectional study.
PloS one 2024 Bagala I, Namuganga JF, Nayebare P, Cuu G, Katairo T, Nabende I, Gonahasa S, Nassali M, Tukwasibwe S, Dorsey G, Nankabirwa JI, Bakeera-Kitaka S, Kiguli S, Greenhouse B, Ssewanyana I, Kamya MR, Briggs … -
Post-treatment duration of positivity for standard and ultra-sensitive Plasmodium falciparum antigen-based rapid diagnostic tests, a cohort study from a low-endemic setting in Namibia.
EBioMedicine 2024 Ntuku H, Whittemore B, Dausab L, Jang IK, Golden A, Sheahan W, Wu X, Slater H, Domingo GJ, Das S, Duarte E, Eloff L, Bousema T, Lanke K, Gueye CS, Prach LM, Raman J, Uusiku P, Katokele S, Gosling R, … -
Plasmodium falciparum molecular surveillance to inform the Mozambican National Malaria Control Programme strategy: protocol.
BMJ open 2024 da Silva C, Matambisso G, Boene S, Rovira-Vallbona E, Pujol A, Comiche K, Sánchez A, Greenhouse B, Chidimatembue A, Aranda-Díaz A, Arnaldo P, Ariani C, Walker P, Mbeve H, Ndimande N, Tembisse D, … -
Broadly inhibitory antibodies to severe malaria virulence proteins.
Nature 2024 Reyes RA, Raghavan SSR, Hurlburt NK, Introini V, Bol S, Kana IH, Jensen RW, Martinez-Scholze E, Gestal-Mato M, López-Gutiérrez B, Sanz S, Bancells C, Fernández-Quintero ML, Loeffler JR, Ferguson JA, … -
Natural killer cell antibody-dependent cellular cytotoxicity to Plasmodium falciparum is impacted by cellular phenotypes, erythrocyte polymorphisms, parasite diversity and intensity of transmission.
Clinical & translational immunology 2024 Tukwasibwe S, Lewis SN, Taremwa Y, van der Ploeg K, Press KD, Ty M, Namirimu Nankya F, Musinguzi K, Nansubuga E, Bach F, Chamai M, Okitwi M, Tumusiime G, Nakimuli A, Colucci F, Kamya MR, Nankabirwa JI… -
Differences in phenotype between long-lived memory B cells against Plasmodium falciparum merozoite antigens and variant surface antigens.
PLoS pathogens 2024 Reyes RA, Turner L, Ssewanyana I, Jagannathan P, Feeney ME, Lavstsen T, Greenhouse B, Bol S, Bunnik EM -
Review of MrsFreqPhase methods: methods designed to estimate statistically malaria parasite multiplicity of infection, relatedness, frequency and phase.
Malaria journal 2024 Taylor AR, Neubauer Vickers E, Greenhouse B -
MOIRE: a software package for the estimation of allele frequencies and effective multiplicity of infection from polyallelic data.
Bioinformatics (Oxford, England) 2024 Murphy M, Greenhouse B -
Author Correction: Population genomics of virulence genes of Plasmodium falciparum in clinical isolates from Uganda.
Scientific reports 2024 Ruybal-Pesántez S, Tiedje KE, Tonkin-Hill G, Rask TS, Kamya MR, Greenhouse B, Dorsey G, Duffy MF, Day KP -
Genomic epidemiology demonstrates spatially clustered, local transmission of Plasmodium falciparum in forest-going populations in southern Lao PDR.
PLoS pathogens 2024 Chen YA, Vickers EN, Aranda-Diaz A, Murphy M, Gerlovina I, Rerolle F, Dantzer E, Hongvanthong B, Chang HH, Lover AA, Hathaway NJ, Bennett A, Greenhouse B -
Gestational SARS-CoV-2 Infection in a Ugandan Birth Cohort: High Incidence, Mild Maternal Disease, and Evidence of Association with Transient Infant Stunting.
The American journal of tropical medicine and hygiene 2024 Jacobson KB, Röltgen K, Lam B, Nayebare P, Kakuru A, Kizza J, Aguti M, Nankya F, Briggs J, Takahashi S, Greenhouse B, Rodriguez-Barraquer I, van der Ploeg K, Wohlstadter JN, Sigal GB, Roh ME, … -
Infection length and host environment influence on Plasmodium falciparum dry season reservoir.
EMBO molecular medicine 2024 Andrade CM, Carrasquilla M, Dabbas U, Briggs J, van Dijk H, Sergeev N, Sissoko A, Niangaly M, Ntalla C, LaVerriere E, Skinner J, Golob K, Richter J, Cisse H, Li S, Hendry JA, Asghar M, Doumtabe D, … -
Dramatic resurgence of malaria after 7 years of intensive vector control interventions in Eastern Uganda.
PLOS global public health 2024 Kamya MR, Nankabirwa JI, Arinaitwe E, Rek J, Zedi M, Maiteki-Sebuguzi C, Opigo J, Staedke SG, Oruni A, Donnelly MJ, Greenhouse B, Briggs J, Krezanoski PJ, Bousema T, Rosenthal PJ, Olwoch P, … -
Varied Prevalence of Antimalarial Drug Resistance Markers in Different Populations of Newly Arrived Refugees in Uganda.
The Journal of infectious diseases 2024 Tukwasibwe S, Garg S, Katairo T, Asua V, Kagurusi BA, Mboowa G, Crudale R, Tumusiime G, Businge J, Alula D, Kasozi J, Wadembere I, Ssewanyana I, Arinaitwe E, Nankabirwa JI, Nsobya SL, Kamya MR, … -
Clinical immunity to malaria involves epigenetic reprogramming of innate immune cells.
PNAS Nexus 2024 Jason Nideffer, Maureen Ty, Michele Donato, Rek John, Richard Kajubi, Xuhuai Ji, Felistas Nankya, Kenneth Musinguzi, Kathleen Dantzler Press, Nora Yang, Kylie Camanag, Bryan Greenhouse, Moses Kamya, … -
MOIRE: A software package for the estimation of allele frequencies and effective multiplicity of infection from polyallelic data.
bioRxiv : the preprint server for biology 2024 Murphy M, Greenhouse B -
Genetic surveillance reveals low, sustained malaria transmission with clonal replacement in Sao Tome and Principe.
medRxiv : the preprint server for health sciences 2024 Chen YA, Ng PY, Garcia D, Elliot A, Palmer B, Assunção Carvalho RMC, Tseng LF, Lee CS, Tsai KH, Greenhouse B, Chang HH -
Seroprevalence of SARS-CoV-2 and risk factors for infection among children in Uganda: a serial cross-sectional study.
medRxiv : the preprint server for health sciences 2024 Bagala I, Namuganga JF, Nayebare P, Cuu G, Katairo T, Nabende I, Gonahasa S, Nassali M, Tukwasibwe S, Dorsey G, Nankabirwa J, Kitaka SB, Kiguli S, Greenhouse B, Ssewanyana I, Kamya MR, Briggs J -
Differences in phenotype between long-lived memory B cells against Plasmodium falciparum merozoite antigens and variant surface antigens.
bioRxiv : the preprint server for biology 2024 Reyes RA, Turner L, Ssewanyana I, Jagannathan P, Feeney ME, Lavstsen T, Greenhouse B, Bol S, Bunnik EM -
Dramatic resurgence of malaria after 7 years of intensive vector control interventions in Eastern Uganda.
medRxiv : the preprint server for health sciences 2024 Kamya MR, Nankabirwa JI, Arinaitwe E, Rek J, Zedi M, Maiteki-Sebuguzi C, Opigo J, Staedke SG, Oruni A, Donnelly MJ, Greenhouse B, Briggs J, Krezanoski PJ, Bousema T, Rosenthal PJ, Olwoch P, … -
Genomic malaria surveillance of antenatal care users detects reduced transmission following elimination interventions in Mozambique.
Nature communications 2024 Brokhattingen N, Matambisso G, da Silva C, Neubauer Vickers E, Pujol A, Mbeve H, Cisteró P, Maculuve S, Cuna B, Melembe C, Ndimande N, Palmer B, García-Ulloa M, Munguambe H, Montaña-Lopez J, Nhamussua… -
Broadly inhibitory antibodies against severe malaria virulence proteins.
bioRxiv : the preprint server for biology 2024 Reyes RA, Raghavan SSR, Hurlburt NK, Introini V, Kana IH, Jensen RW, Martinez-Scholze E, Gestal-Mato M, Bau CB, Fernández-Quintero ML, Loeffler JR, Ferguson JA, Lee WH, Martin GM, Theander TG, … -
Genetic complexity alters drug susceptibility of asexual and gametocyte stages of Plasmodium falciparum to antimalarial candidates.
Antimicrobial agents and chemotherapy 2024 Greyling N, van der Watt M, Gwarinda H, van Heerden A, Greenhouse B, Leroy D, Niemand J, Birkholtz L-M -
Atypical B cells consist of subsets with distinct functional profiles.
iScience 2023 Reyes RA, Batugedara G, Dutta P, Reers AB, Garza R, Ssewanyana I, Jagannathan P, Feeney ME, Greenhouse B, Bol S, Ay F, Bunnik EM -
Genomic malaria surveillance of antenatal care users detects reduced transmission following elimination interventions in Mozambique.
Research square 2023 Mayor A, Brokhattingen N, Matambisso G, da Silva C, Vickers EN, Pujol A, Mbeve H, Cistero P, Maculuve S, Cuna B, Melembe C, Ndimande N, Palmer B, García M, Munguambe H, Lopez JM, Nhamussa L, Simone W,… -
The breadth of the neutralizing antibody response to original SARS-CoV-2 infection is linked to the presence of Long COVID symptoms.
Journal of medical virology 2023 Buck AM, Deitchman AN, Takahashi S, Lu S, Goldberg SA, Bodansky A, Kung A, Hoh R, Williams MC, Kerbleski M, Maison DP, Deveau TM, Munter SE, Lombardo J, Wrin T, Petropoulos CJ, Durstenfeld MS, Hsue PY… -
Evidence for a role of Anopheles stephensi in the spread of drug- and diagnosis-resistant malaria in Africa.
Nature medicine 2023 Emiru T, Getachew D, Murphy M, Sedda L, Ejigu LA, Bulto MG, Byrne I, Demisse M, Abdo M, Chali W, Elliott A, Vickers EN, Aranda-Díaz A, Alemayehu L, Behaksera SW, Jebessa G, Dinka H, Tsegaye T, Teka H,… -
SARS-CoV-2 Serology Across Scales: A Framework for Unbiased Estimation of Cumulative Incidence Incorporating Antibody Kinetics and Epidemic Recency.
American journal of epidemiology 2023 Takahashi S, Peluso MJ, Hakim J, Turcios K, Janson O, Routledge I, Busch MP, Hoh R, Tai V, Kelly JD, Martin JN, Deeks SG, Henrich TJ, Greenhouse B, Rodríguez-Barraquer I -
Population structure and genetic connectivity of Plasmodium falciparum in pre-elimination settings of Southern Africa.
Frontiers in epidemiology 2023 Gwarinda HB, Tessema SK, Raman J, Greenhouse B, Birkholtz LM -
An optimized GATK4 pipeline for Plasmodium falciparum whole genome sequencing variant calling and analysis.
Malaria journal 2023 Niaré K, Greenhouse B, Bailey JA -
Autoantigen profiling reveals a shared post-COVID signature in fully recovered and long COVID patients.
JCI insight 2023 Bodansky A, Wang CY, Saxena A, Mitchell A, Kung AF, Takahashi S, Anglin K, Huang B, Hoh R, Lu S, Goldberg SA, Romero J, Tran B, Kirtikar R, Grebe H, So M, Greenhouse B, Durstenfeld MS, Hsue PY, … -
Targeted and whole-genome sequencing reveal a north-south divide in P. falciparum drug resistance markers and genetic structure in Mozambique.
Communications biology 2023 da Silva C, Boene S, Datta D, Rovira-Vallbona E, Aranda-Díaz A, Cisteró P, Hathaway N, Tessema S, Chidimatembue A, Matambisso G, Nhama A, Macete E, Pujol A, Nhamussua L, Galatas B, Guinovart C, Enosse… -
Metagenomic next-generation sequencing to characterize potential etiologies of non-malarial fever in a cohort living in a high malaria burden area of Uganda.
PLOS global public health 2023 Mwakibete L, Takahashi S, Ahyong V, Black A, Rek J, Ssewanyana I, Kamya M, Dorsey G, Jagannathan P, Rodríguez-Barraquer I, Tato CM, Greenhouse B -
MultiSero: An Open-Source Multiplex-ELISA Platform for Measuring Antibody Responses to Infection.
Pathogens (Basel, Switzerland) 2023 Byrum JR, Waltari E, Janson O, Guo SM, Folkesson J, Chhun BB, Vinden J, Ivanov IE, Forst ML, Li H, Larson AG, Blackmon L, Liu Z, Wu W, Ahyong V, Tato CM, McCutcheon KM, Hoh R, Kelly JD, Martin JN, … -
Analysis of naturally acquired immune responses against the Plasmodium falciparum malaria vaccine candidate PF3D7_1136200.
The Journal of Immunology 2023 Rolando Garza, Ashley Reers, Raphael Reyes, Isaac Ssewanyana, Bryan Greenhouse, Sebastiaan Bol, Evelien Bunnik -
Mapping malaria incidence using routine health facility surveillance data in Uganda.
BMJ global health 2023 Epstein A, Namuganga JF, Nabende I, Kamya EV, Kamya MR, Dorsey G, Sturrock H, Bhatt S, Rodríguez-Barraquer I, Greenhouse B -
Plasmodium falciparum gametocyte carriage in longitudinally monitored incident infections is associated with duration of infection and human host factors.
Scientific reports 2023 Andolina C, Ramjith J, Rek J, Lanke K, Okoth J, Grignard L, Arinaitwe E, Briggs J, Bailey J, Aydemir O, Kamya MR, Greenhouse B, Dorsey G, Staedke SG, Drakeley C, Jonker M, Bousema T -
Plasticity of atypical B cell composition and function in response to malaria.
The Journal of Immunology 2023 Raphael Reyes, Gayani Batugedara, Paramita Dutta, Ashley Reers, Bryan Greenhouse, Sebastiaan Bol, Ferhat Ay, Evelien Bunnik -
The Breadth of the Neutralizing Antibody Response to Original SARS-CoV-2 Infection is Linked to the Presence of Long COVID Symptoms.
medRxiv : the preprint server for health sciences 2023 Buck AM, Deitchman AN, Takahashi S, Lu S, Goldberg SA, Hoh R, Williams MC, Kerbleski M, Deveau TM, Munter SE, Lombardo J, Wrin T, Petropoulos CJ, Durstenfeld MS, Hsue PY, Kelly JD, Greenhouse B, … -
Antibodies to repeat-containing antigens in Plasmodium falciparum are exposure-dependent and short-lived in children in natural malaria infections.
eLife 2023 Raghavan M, Kalantar KL, Duarte E, Teyssier N, Takahashi S, Kung AF, Rajan JV, Rek J, Tetteh KKA, Drakeley C, Ssewanyana I, Rodriguez-Barraquer I, Greenhouse B, DeRisi JL -
An Optimized GATK4 Pipeline for Plasmodium falciparum Whole Genome Sequencing Variant Calling and Analysis.
Research square 2023 Niaré K, Greenhouse B, Bailey JA -
Highly potent, naturally acquired human monoclonal antibodies against Pfs48/45 block Plasmodium falciparum transmission to mosquitoes.
Immunity 2023 Fabra-García A, Hailemariam S, de Jong RM, Janssen K, Teelen K, van de Vegte-Bolmer M, van Gemert GJ, Ivanochko D, Semesi A, McLeod B, Vos MW, de Bruijni MHC, Bolscher JM, Szabat M, Vogt S, Kraft L, … -
Potent transmission-blocking monoclonal antibodies from naturally exposed individuals target a conserved epitope on Plasmodium falciparum Pfs230.
Immunity 2023 Ivanochko D, Fabra-García A, Teelen K, van de Vegte-Bolmer M, van Gemert GJ, Newton J, Semesi A, de Bruijni M, Bolscher J, Ramjith J, Szabat M, Vogt S, Kraft L, Duncan S, Lee SM, Kamya MR, Feeney ME, … -
Autoantigen profiling reveals a shared post-COVID signature in fully recovered and Long COVID patients.
medRxiv : the preprint server for health sciences 2023 Bodansky A, Wang CY, Saxena A, Mitchell A, Takahashi S, Anglin K, Huang B, Hoh R, Lu S, Goldberg SA, Romero J, Tran B, Kirtikar R, Grebe H, So M, Greenhouse B, Durstenfeld MS, Hsue PY, Hellmuth J, … -
Seroprevalence of Antibodies to SARS-CoV-2 in Rural Households in Eastern Uganda, 2020-2022.
JAMA network open 2023 Briggs J, Takahashi S, Nayebare P, Cuu G, Rek J, Zedi M, Kizza T, Arinaitwe E, Nankabirwa JI, Kamya M, Jagannathan P, Jacobson K, Rosenthal PJ, Dorsey G, Greenhouse B, Ssewanyana I, Rodríguez-… -
Malaria-driven expansion of adaptive-like functional CD56-negative NK cells correlates with clinical immunity to malaria.
Science translational medicine 2023 Ty M, Sun S, Callaway PC, Rek J, Press KD, van der Ploeg K, Nideffer J, Hu Z, Klemm S, Greenleaf W, Donato M, Tukwasibwe S, Arinaitwe E, Nankya F, Musinguzi K, Andrew D, de la Parte L, Mori DM, Lewis … -
Low Prevalence of Interferon α Autoantibodies in People Experiencing Symptoms of Post-Coronavirus Disease 2019 (COVID-19) Conditions, or Long COVID.
The Journal of infectious diseases 2023 Peluso MJ, Mitchell A, Wang CY, Takahashi S, Hoh R, Tai V, Durstenfeld MS, Hsue PY, Kelly JD, Martin JN, Wilson MR, Greenhouse B, Deeks SG, DeRisi JL, Henrich TJ -
Measures of malaria transmission, infection, and disease in an area bordering two districts with and without sustained indoor residual spraying of insecticide in Uganda.
PloS one 2022 Nankabirwa JI, Bousema T, Blanken SL, Rek J, Arinaitwe E, Greenhouse B, Rosenthal PJ, Kamya MR, Staedke SG, Dorsey G -
Early immune markers of clinical, virological, and immunological outcomes in patients with COVID-19: a multi-omics study.
eLife 2022 Hu Z, van der Ploeg K, Chakraborty S, Arunachalam PS, Mori DAM, Jacobson KB, Bonilla H, Parsonnet J, Andrews JR, Holubar M, Subramanian A, Khosla C, Maldonado Y, Hedlin H, de la Parte L, Press K, Ty M… -
East Africa International Center of Excellence for Malaria Research: Summary of Key Research Findings.
The American journal of tropical medicine and hygiene 2022 Nankabirwa JI, Rek J, Arinaitwe E, Namuganga JF, Nsobya SL, Asua V, Mawejje HD, Epstein A, Greenhouse B, Rodriguez-Barraquer I, Briggs J, Krezanoski PJ, Rosenthal PJ, Conrad M, Smith D, Staedke SG, … -
Simulating the Impacts of Augmenting Intensive Vector Control with Mass Drug Administration or Test-and-Treat Strategies on the Malaria Infectious Reservoir.
The American journal of tropical medicine and hygiene 2022 Nankabirwa JI, Arinaitwe E, Briggs J, Rek J, Rosenthal PJ, Kamya MR, Olwoch P, Smith DL, Rodriguez-Barraquer I, Dorsey G, Greenhouse B -
Dcifer: an IBD-based method to calculate genetic distance between polyclonal infections.
Genetics 2022 Gerlovina I, Gerlovin B, Rodríguez-Barraquer I, Greenhouse B -
Reconstructing the SARS-CoV-2 epidemic in eastern Uganda through longitudinal serosurveillance in a malaria cohort.
medRxiv : the preprint server for health sciences 2022 Briggs J, Takahashi S, Nayebare P, Cuu G, Rek J, Zedi M, Kizza T, Arinaitwe E, Nankabirwa JI, Kamya M, Jagannathan P, Jacobson K, Rosenthal PJ, Dorsey G, Greenhouse B, Ssewanyana I, Rodríguez-… -
Resurgence of malaria in Uganda despite sustained indoor residual spraying and repeated long lasting insecticidal net distributions.
PLOS global public health 2022 Epstein A, Maiteki-Sebuguzi C, Namuganga JF, Nankabirwa JI, Gonahasa S, Opigo J, Staedke SG, Rutazaana D, Arinaitwe E, Kamya MR, Bhatt S, Rodríguez-Barraquer I, Greenhouse B, Donnelly MJ, Dorsey G -
Plasmodium falciparum serology: A comparison of two protein production methods for analysis of antibody responses by protein microarray.
PloS one 2022 Oulton T, Obiero J, Rodriguez I, Ssewanyana I, Dabbs RA, Bachman CM, Greenhouse B, Drakeley C, Felgner PL, Stone W, Tetteh KKA -
Automated Recognition of Plasmodium falciparum Parasites from Portable Blood Levitation Imaging.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Deshmukh SS, Byaruhanga O, Tumwebaze P, Akin D, Greenhouse B, Egan ES, Demirci U -
Age-dependent changes in circulating Tfh cells influence development of functional malaria antibodies in children.
Nature communications 2022 Chan JA, Loughland JR, de la Parte L, Okano S, Ssewanyana I, Nalubega M, Nankya F, Musinguzi K, Rek J, Arinaitwe E, Tipping P, Bourke P, Andrew D, Dooley N, SheelaNair A, Wines BD, Hogarth PM, Beeson … -
Prospective surveillance study to detect antimalarial drug resistance, gene deletions of diagnostic relevance and genetic diversity of Plasmodium falciparum in Mozambique: protocol.
BMJ open 2022 Mayor A, da Silva C, Rovira-Vallbona E, Roca-Feltrer A, Bonnington C, Wharton-Smith A, Greenhouse B, Bever C, Chidimatembue A, Guinovart C, Proctor JL, Rodrigues M, Canana N, Arnaldo P, Boene S, Aide … -
A Molecular Analysis of Memory B Cell and Antibody Responses Against Plasmodium falciparum Merozoite Surface Protein 1 in Children and Adults From Uganda.
Frontiers in immunology 2022 Gonzales SJ, Clarke KN, Batugedara G, Garza R, Braddom AE, Reyes RA, Ssewanyana I, Garrison KC, Ippolito GC, Greenhouse B, Bol S, Bunnik EM -
Using sero-epidemiology to monitor disparities in vaccination and infection with SARS-CoV-2.
Nature communications 2022 Routledge I, Takahashi S, Epstein A, Hakim J, Janson O, Turcios K, Vinden J, Risos JT, Baniqued MR, Pham L, Di Germanio C, Busch M, Kushel M, Greenhouse B, Rodríguez-Barraquer I -
TNF-α+ CD4+ T cells dominate the SARS-CoV-2 specific T cell response in COVID-19 outpatients and are associated with durable antibodies.
Cell reports. Medicine 2022 van der Ploeg K, Kirosingh AS, Mori DAM, Chakraborty S, Hu Z, Sievers BL, Jacobson KB, Bonilla H, Parsonnet J, Andrews JR, Press KD, Ty MC, Ruiz-Betancourt DR, de la Parte L, Tan GS, Blish CA, … -
Sensitive, Highly Multiplexed Sequencing of Microhaplotypes From the Plasmodium falciparum Heterozygome.
The Journal of infectious diseases 2022 Tessema SK, Hathaway NJ, Teyssier NB, Murphy M, Chen A, Aydemir O, Duarte EM, Simone W, Colborn J, Saute F, Crawford E, Aide P, Bailey JA, Greenhouse B -
Inferring person-to-person networks of Plasmodium falciparum transmission: are analyses of routine surveillance data up to the task?
Malaria journal 2022 Huber JH, Hsiang MS, Dlamini N, Murphy M, Vilakati S, Nhlabathi N, Lerch A, Nielsen R, Ntshalintshali N, Greenhouse B, Perkins TA -
Serological evaluation of the effectiveness of reactive focal mass drug administration and reactive vector control to reduce malaria transmission in Zambezi Region, Namibia: Results from a secondary analysis of a cluster randomised trial.
EClinicalMedicine 2022 Wu L, Hsiang MS, Prach LM, Schrubbe L, Ntuku H, Dufour MK, Whittemore B, Scott V, Yala J, Roberts KW, Patterson C, Biggs J, Hall T, Tetteh KKA, Gueye CS, Greenhouse B, Bennett A, Smith JL, Katokele S,… -
Early immune responses have long-term associations with clinical, virologic, and immunologic outcomes in patients with COVID-19.
Research square 2022 Hu Z, van der Ploeg K, Chakraborty S, Arunachalam P, Mori D, Jacobson K, Bonilla H, Parsonnet J, Andrews J, Hedlin H, de la Parte L, Dantzler K, Ty M, Tan G, Blish C, Takahashi S, Rodriguez-Barraquer … -
A Novel Malaria Lateral Flow Assay for Detecting Plasmodium falciparum Lactate Dehydrogenase in Busia, Uganda.
The American journal of tropical medicine and hygiene 2022 Bachman CM, Cate DM, Grant B, Burkot S, Mulondo J, Hsieh HV, Chamai M, Odongo B, Olwoch P, Nalubega M, Ochokoru H, Kasozi J, Ategeka J, Nichols KP, Weigl BH, Greenhouse B -
Persistence, Magnitude, and Patterns of Postacute Symptoms and Quality of Life Following Onset of SARS-CoV-2 Infection: Cohort Description and Approaches for Measurement.
Open forum infectious diseases 2021 Peluso MJ, Kelly JD, Lu S, Goldberg SA, Davidson MC, Mathur S, Durstenfeld MS, Spinelli MA, Hoh R, Tai V, Fehrman EA, Torres L, Hernandez Y, Williams MC, Arreguin MI, Ngo LH, Deswal M, Munter SE, … -
Markers of Immune Activation and Inflammation in Individuals With Postacute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 Infection.
The Journal of infectious diseases 2021 Peluso MJ, Lu S, Tang AF, Durstenfeld MS, Ho HE, Goldberg SA, Forman CA, Munter SE, Hoh R, Tai V, Chenna A, Yee BC, Winslow JW, Petropoulos CJ, Greenhouse B, Hunt PW, Hsue PY, Martin JN, Daniel Kelly … -
Longitudinal analysis of FcRL5 expression and clonal relationships among classical and atypical memory B cells following malaria.
Malaria journal 2021 Gonzales SJ, Bol S, Braddom AE, Sullivan R, Reyes RA, Ssewanyana I, Eggers E, Greenhouse B, Bunnik EM -
Using sero-epidemiology to monitor disparities in vaccination and infection with SARS-CoV-2.
medRxiv : the preprint server for health sciences 2021 Routledge I, Takahashi S, Epstein A, Hakim J, Janson O, Turcios K, Vinden J, Risos JT, Baniqued MR, Pham L, Di Germanio C, Busch M, Kushel M, Greenhouse B, Rodríguez-Barraquer I -
B Cell Receptor Repertoire Analysis in Malaria-Naive and Malaria-Experienced Individuals Reveals Unique Characteristics of Atypical Memory B Cells.
mSphere 2021 Braddom AE, Bol S, Gonzales SJ, Reyes RA, Musinguzi K, Nankya F, Ssewanyana I, Greenhouse B, Bunnik EM -
SARS-CoV-2 serology across scales: a framework for unbiased seroprevalence estimation incorporating antibody kinetics and epidemic recency.
medRxiv : the preprint server for health sciences 2021 Takahashi S, Peluso MJ, Hakim J, Turcios K, Janson O, Routledge I, Busch MP, Hoh R, Tai V, Kelly JD, Martin JN, Deeks SG, Henrich TJ, Greenhouse B, Rodríguez-Barraquer I -
Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19.
Science translational medicine 2021 van der Wijst MGP, Vazquez SE, Hartoularos GC, Bastard P, Grant T, Bueno R, Lee DS, Greenland JR, Sun Y, Perez R, Ogorodnikov A, Ward A, Mann SA, Lynch KL, Yun C, Havlir DV, Chamie G, Marquez C, … -
Impact of COVID-19 on routine malaria indicators in Uganda: An interrupted time series analysis.
Research square 2021 Namuganga JF, Briggs J, Roh ME, Okiring J, Kisambira Y, Sserwanga A, Kapisi JA, Arinaitwe E, Ebong C, Ssewanyana I, Greenhouse B, Maiteki-Ssebuguzi C, Kamya MR, Staedke SG, Dorsey G, Nankabirwa JI -
Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms.
Cell reports 2021 Peluso MJ, Deitchman AN, Torres L, Iyer NS, Munter SE, Nixon CC, Donatelli J, Thanh C, Takahashi S, Hakim J, Turcios K, Janson O, Hoh R, Tai V, Hernandez Y, Fehrman EA, Spinelli MA, Gandhi M, Trinh L,… -
Community Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 Disproportionately Affects the Latinx Population During Shelter-in-Place in San Francisco.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2021 Chamie G, Marquez C, Crawford E, Peng J, Petersen M, Schwab D, Schwab J, Martinez J, Jones D, Black D, Gandhi M, Kerkhoff AD, Jain V, Sergi F, Jacobo J, Rojas S, Tulier-Laiwa V, Gallardo-Brown T, Appa… -
SARS-CoV-2 antibody magnitude and detectability are driven by disease severity, timing, and assay.
Science advances 2021 Peluso MJ, Takahashi S, Hakim J, Kelly JD, Torres L, Iyer NS, Turcios K, Janson O, Munter SE, Thanh C, Donatelli J, Nixon CC, Hoh R, Tai V, Fehrman EA, Hernandez Y, Spinelli MA, Gandhi M, Palafox MA, … -
SARS-CoV-2 PCR and antibody testing for an entire rural community: methods and feasibility of high-throughput testing procedures.
Archives of public health = Archives belges de sante publique 2021 Appa A, Chamie G, Sawyer A, Baltzell K, Dippell K, Ribeiro S, Duarte E, Vinden J, Consortium C, Kramer-Feldman J, Rahdari S, MacIntosh D, Nicholson K, Im J, Havlir D, Greenhouse B -
Sources of persistent malaria transmission in a setting with effective malaria control in eastern Uganda: a longitudinal, observational cohort study.
The Lancet. Infectious diseases 2021 Andolina C, Rek JC, Briggs J, Okoth J, Musiime A, Ramjith J, Teyssier N, Conrad M, Nankabirwa JI, Lanke K, Rodriguez-Barraquer I, Meerstein-Kessel L, Arinaitwe E, Olwoch P, Rosenthal PJ, Kamya MR, … -
Citywide serosurveillance of the initial SARS-CoV-2 outbreak in San Francisco using electronic health records.
Nature communications 2021 Routledge I, Epstein A, Takahashi S, Janson O, Hakim J, Duarte E, Turcios K, Vinden J, Sujishi K, Rangel J, Coh M, Besana L, Ho WK, Oon CY, Ong CM, Yun C, Lynch K, Wu AHB, Wu W, Karlon W, Thornborrow … -
Multiparametric biophysical profiling of red blood cells in malaria infection.
Communications biology 2021 Deshmukh SS, Shakya B, Chen A, Durmus NG, Greenhouse B, Egan ES, Demirci U -
Effectiveness and safety of reactive focal mass drug administration (rfMDA) using dihydroartemisinin-piperaquine to reduce malaria transmission in the very low-endemic setting of Eswatini: a pragmatic cluster randomised controlled trial.
BMJ global health 2021 Vilakati S, Mngadi N, Benjamin-Chung J, Dlamini N, Dufour MK, Whittemore B, Bhangu K, Prach LM, Baltzell K, Nhlabathi N, Malambe C, Dlamini B, Helb D, Greenhouse B, Maphalala G, Pindolia D, Kalungero … -
multiSero: open multiplex-ELISA platform for analyzing antibody responses to SARS-CoV-2 infection.
medRxiv : the preprint server for health sciences 2021 Byrum JR, Waltari E, Janson O, Guo SM, Folkesson J, Chhun BB, Vinden J, Ivanov IE, Forst ML, Li H, Larson AG, Wu W, Tato CM, McCutcheon KM, Peluso MJ, Henrich TJ, Deeks SG, Prakash M, Greenhouse B, … -
Comparison of infection control strategies to reduce COVID-19 outbreaks in homeless shelters in the United States: a simulation study.
BMC medicine 2021 Chapman LAC, Kushel M, Cox SN, Scarborough A, Cawley C, Nguyen TQ, Rodriguez-Barraquer I, Greenhouse B, Imbert E, Lo NC -
Plasmodium falciparum -specific B cell responses in malaria-susceptible children and malaria-immune adults.
The Journal of Immunology 2021 Stephen Jacob Gonzales, Raphael Reyes, Gayani Batugedara, Isaac Ssewanyana, John Rek, Jason J Lavinder, Gregory C Ippolito, Sebastiaan Bol, Bryan Greenhouse, Evelien Bunnik -
Probing the naturally acquired immune response to malaria for broadly reactive antibodies targeting P. falciparum antigens linked with severe disease.
The Journal of Immunology 2021 Raphael Reyes, Louise Turner, Isaac Ssewanyana, John Rek, Bryan Greenhouse, Sebastiaan Bol, Thomas Lavstsen, Evelien Bunnik -
The origin and fate of malaria-associated atypical memory B cells.
The Journal of Immunology 2021 Evelien M Bunnik, Gayani Batugedara, Ashley Braddom, Richard Sullivan, Jake Gonzales, Raphael Reyes, Isaac Ssewanyana, Bryan Greenhouse, Sebastiaan Bol -
91074 Identification of monoclonal antibodies with broad reactivity against the malaria parasite variant surface antigen responsible for severe malaria.
Journal of Clinical and Translational Science 2021 Raphael Reyes, Louise Turner, Isaac Ssewanyana, John Rek, Bryan Greenhouse, Sebastiaan Bol, Thomas Lavstsen, Evelien M. Bunnik -
Engineering luminescent biosensors for point-of-care SARS-CoV-2 antibody detection.
Nature biotechnology 2021 Elledge SK, Zhou XX, Byrnes JR, Martinko AJ, Lui I, Pance K, Lim SA, Glasgow JE, Glasgow AA, Turcios K, Iyer NS, Torres L, Peluso MJ, Henrich TJ, Wang TT, Tato CM, Leung KK, Greenhouse B, Wells JA -
Routine asymptomatic testing strategies for airline travel during the COVID-19 pandemic: a simulation study.
The Lancet. Infectious diseases 2021 Kiang MV, Chin ET, Huynh BQ, Chapman LAC, Rodríguez-Barraquer I, Greenhouse B, Rutherford GW, Bibbins-Domingo K, Havlir D, Basu S, Lo NC -
Rapid implementation of a cohort for the study of post-acute sequelae of SARS-CoV-2 infection/COVID-19.
medRxiv : the preprint server for health sciences 2021 Peluso MJ, Kelly JD, Lu S, Goldberg SA, Davidson MC, Mathur S, Durstenfeld MS, Spinelli MA, Hoh R, Tai V, Fehrman EA, Torres L, Hernandez Y, Williams MC, Arreguin MI, Bautista JA, Ngo LH, Deswal M, … -
Longitudinal single-cell epitope and RNA-sequencing reveals the immunological impact of type 1 interferon autoantibodies in critical COVID-19: Anti-IFN antibodies in critical COVID-19 correlate with poor ISG response and upregulation of LAIR1 surface protein in PBMCs.
bioRxiv : the preprint server for biology 2021 van der Wijst MGP, Vazquez SE, Hartoularos GC, Bastard P, Grant T, Bueno R, Lee DS, Greenland JR, Sun Y, Perez R, Ogorodnikov A, Ward A, Mann SA, Lynch KL, Yun C, Havlir DV, Chamie G, Marquez C, … -
SARS-CoV-2 antibody magnitude and detectability are driven by disease severity, timing, and assay.
medRxiv : the preprint server for health sciences 2021 Peluso MJ, Takahashi S, Hakim J, Kelly JD, Torres L, Iyer NS, Turcios K, Janson O, Munter SE, Thanh C, Nixon CC, Hoh R, Tai V, Fehrman EA, Hernandez Y, Spinelli MA, Gandhi M, Palafox MA, Vallari A, … -
Long-Term SARS-CoV-2-Specific Immune and Inflammatory Responses Across a Clinically Diverse Cohort of Individuals Recovering from COVID-19.
medRxiv : the preprint server for health sciences 2021 Peluso MJ, Deitchman AN, Torres L, Iyer NS, Nixon CC, Munter SE, Donatelli J, Thanh C, Takahashi S, Hakim J, Turcios K, Janson O, Hoh R, Tai V, Hernandez Y, Fehrman E, Spinelli MA, Gandhi M, Trinh L, … -
Optimization of whole-genome sequencing of Plasmodium falciparum from low-density dried blood spot samples.
Malaria journal 2021 Teyssier NB, Chen A, Duarte EM, Sit R, Greenhouse B, Tessema SK -
Parasite genetic diversity reflects continued residual malaria transmission in Vhembe District, a hotspot in the Limpopo Province of South Africa.
Malaria journal 2021 Gwarinda HB, Tessema SK, Raman J, Greenhouse B, Birkholtz LM -
Characterization and Biomarker Analyses of Post-COVID-19 Complications and Neurological Manifestations.
Cells 2021 Sun B, Tang N, Peluso MJ, Iyer NS, Torres L, Donatelli JL, Munter SE, Nixon CC, Rutishauser RL, Rodriguez-Barraquer I, Greenhouse B, Kelly JD, Martin JN, Deeks SG, Henrich TJ, Pulliam L -
Citywide serosurveillance of the initial SARS-CoV-2 outbreak in San Francisco.
Research square 2021 Routledge I, Epstein A, Takahashi S, Janson O, Hakim J, Duarte E, Turcios K, Vinden J, Sujishi K, Rangel J, Coh M, Besana L, Ho WK, Oon CY, Ong CM, Yun C, Lynch K, Wu AHB, Wu W, Karlon W, Thornborrow … -
Persistent COVID-19-associated neurocognitive symptoms in non-hospitalized patients.
Journal of neurovirology 2021 Hellmuth J, Barnett TA, Asken BM, Kelly JD, Torres L, Stephens ML, Greenhouse B, Martin JN, Chow FC, Deeks SG, Greene M, Miller BL, Annan W, Henrich TJ, Peluso MJ -
Within-household clustering of genetically related Plasmodium falciparum infections in a moderate transmission area of Uganda.
Malaria journal 2021 Briggs J, Kuchta A, Murphy M, Tessema S, Arinaitwe E, Rek J, Chen A, Nankabirwa JI, Drakeley C, Smith D, Bousema T, Kamya M, Rodriguez-Barraquer I, Staedke S, Dorsey G, Rosenthal PJ, Greenhouse B -
Impact of a Rapid Decline in Malaria Transmission on Antimalarial IgG Subclasses and Avidity.
Frontiers in immunology 2021 Ssewanyana I, Rek J, Rodriguez I, Wu L, Arinaitwe E, Nankabirwa JI, Beeson JG, Mayanja-Kizza H, Rosenthal PJ, Dorsey G, Kamya MR, Drakeley C, Greenhouse B, Tetteh KKA -
Evaluating the Performance of Malaria Genetics for Inferring Changes in Transmission Intensity Using Transmission Modeling.
Molecular biology and evolution 2021 Watson OJ, Okell LC, Hellewell J, Slater HC, Unwin HJT, Omedo I, Bejon P, Snow RW, Noor AM, Rockett K, Hubbart C, Nankabirwa JI, Greenhouse B, Chang HH, Ghani AC, Verity R -
Assessment of Plasmodium antigens and CRP in dried blood spots with multiplex malaria array.
Journal of parasitic diseases : official organ of the Indian Society for Parasitology 2021 Jang IK, Aranda S, Barney R, Rashid A, Helwany M, Rek JC, Arinaitwe E, Adrama H, Murphy M, Imwong M, Proux S, Haohankhunnatham W, Ding XC, Nosten F, Greenhouse B, Gamboa D, Domingo GJ -
Supervised Self-Collected SARS-Cov-2 Testing in Classroom-Based Summer Camps to Inform Safe In-Person Learning.
Journal of Pediatrics Perinatology and Child Health 2021 Peter B Cooch, Annalisa Watson, Apryl Olarte, Emily D Crawford, Joseph L DeRisi, Bryan Greenhouse, Jill Hakim, Keirstinne Turcios, Katherine S Pollard, Lee R Atkinson-McEvoy, Raphael Hirsch, Roberta L… -
Routine asymptomatic testing strategies for airline travel during the COVID-19 pandemic: a simulation analysis.
medRxiv : the preprint server for health sciences 2020 Kiang MV, Chin ET, Huynh BQ, Chapman LAC, Rodríguez-Barraquer I, Greenhouse B, Rutherford GW, Bibbins-Domingo K, Havlir D, Basu S, Lo NC -
Estimating malaria incidence from routine health facility-based surveillance data in Uganda.
Malaria journal 2020 Epstein A, Namuganga JF, Kamya EV, Nankabirwa JI, Bhatt S, Rodriguez-Barraquer I, Staedke SG, Kamya MR, Dorsey G, Greenhouse B -
Spatial and genetic clustering of Plasmodium falciparum and Plasmodium vivax infections in a low-transmission area of Ethiopia.
Scientific reports 2020 Tessema SK, Belachew M, Koepfli C, Lanke K, Huwe T, Chali W, Shumie G, Mekuria EF, Drakeley C, Gadisa E, Greenhouse B, Bousema T, Tadesse FG -
Are Seroprevalence Estimates for Severe Acute Respiratory Syndrome Coronavirus 2 Biased?
The Journal of infectious diseases 2020 Takahashi S, Greenhouse B, Rodríguez-Barraquer I -
Universal Polymerase Chain Reaction and Antibody Testing Demonstrate Little to No Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 in a Rural Community.
Open forum infectious diseases 2020 Appa A, Takahashi S, Rodriguez-Barraquer I, Chamie G, Sawyer A, Duarte E, Hakim J, Turcios K, Vinden J, Janson O, Manglik A, Peluso MJ, Deeks SG, Henrich TJ, Torres L, Rodgers M, Hackett J, Chiu C, … -
Sex-based differences in clearance of chronic Plasmodium falciparum infection.
eLife 2020 Briggs J, Teyssier N, Nankabirwa JI, Rek J, Jagannathan P, Arinaitwe E, Bousema T, Drakeley C, Murray M, Crawford E, Hathaway N, Staedke SG, Smith D, Rosenthal PJ, Kamya M, Dorsey G, Rodriguez-… -
Malaria Transmission, Infection, and Disease following Sustained Indoor Residual Spraying of Insecticide in Tororo, Uganda.
The American journal of tropical medicine and hygiene 2020 Nankabirwa JI, Arinaitwe E, Rek J, Kilama M, Kizza T, Staedke SG, Rosenthal PJ, Rodriguez-Barraquer I, Briggs J, Greenhouse B, Bousema T, Drakeley C, Roos DS, Tomko SS, Smith DL, Kamya MR, Dorsey G -
Engineering luminescent biosensors for point-of-care SARS-CoV-2 antibody detection.
medRxiv : the preprint server for health sciences 2020 Elledge SK, Zhou XX, Byrnes JR, Martinko AJ, Lui I, Pance K, Lim SA, Glasgow JE, Glasgow AA, Turcios K, Iyer N, Torres L, Peluso MJ, Henrich TJ, Wang TT, Tato CM, Leung KK, Greenhouse B, Wells JA -
Universal PCR and antibody testing demonstrate little to no transmission of SARS-CoV-2 in a rural community.
medRxiv : the preprint server for health sciences 2020 Appa A, Takahashi S, Rodriguez-Barraquer I, Chamie G, Sawyer A, Consortium C, Duarte E, Hakim J, Turcios K, Vinden J, Janson O, Manglik A, Peluso MJ, Deeks SG, Henrich TJ, Torres L, Rodgers M, Hackett… -
Confirmation of the absence of local transmission and geographic assignment of imported falciparum malaria cases to China using microsatellite panel.
Malaria journal 2020 Liu Y, Tessema SK, Murphy M, Xu S, Schwartz A, Wang W, Cao Y, Lu F, Tang J, Gu Y, Zhu G, Zhou H, Gao Q, Huang R, Cao J, Greenhouse B -
Multiplex Human Malaria Array: Quantifying Antigens for Malaria Rapid Diagnostics.
The American journal of tropical medicine and hygiene 2020 Jang IK, Tyler A, Lyman C, Rek JC, Arinaitwe E, Adrama H, Murphy M, Imwong M, Proux S, Haohankhunnatham W, Barney R, Rashid A, Kalnoky M, Kahn M, Golden A, Nosten F, Greenhouse B, Gamboa D, Domingo GJ -
SARS-CoV-2 PCR and antibody testing for an entire rural community: methods and feasibility of high-throughput testing procedures.
medRxiv : the preprint server for health sciences 2020 Appa A, Chamie G, Sawyer A, Baltzell K, Dippell K, Ribeiro S, Duarte E, Vinden J, CLIAHUB Consortium, Kramer-Feldman J, Rahdari S, MacIntosh D, Nicholson K, Im J, Havlir D, Greenhouse B -
Effectiveness of reactive focal mass drug administration and reactive focal vector control to reduce malaria transmission in the low malaria-endemic setting of Namibia: a cluster-randomised controlled, open-label, two-by-two factorial design trial.
Lancet (London, England) 2020 Hsiang MS, Ntuku H, Roberts KW, Dufour MK, Whittemore B, Tambo M, McCreesh P, Medzihradsky OF, Prach LM, Siloka G, Siame N, Gueye CS, Schrubbe L, Wu L, Scott V, Tessema S, Greenhouse B, Erlank E, … -
High levels of imported asymptomatic malaria but limited local transmission in KwaZulu-Natal, a South African malaria-endemic province nearing malaria elimination.
Malaria journal 2020 Raman J, Gast L, Balawanth R, Tessema S, Brooke B, Maharaj R, Munhenga G, Tshikae P, Lakan V, Mwamba T, Makowa H, Sangweni L, Mkhabela M, Zondo N, Mohulatsi E, Nyawo Z, Ngxongo S, Msimang S, Dagata N,… -
Rapid shifts in the age-specific burden of malaria following successful control interventions in four regions of Uganda.
Malaria journal 2020 Kigozi SP, Kigozi RN, Epstein A, Mpimbaza A, Sserwanga A, Yeka A, Nankabirwa JI, Halliday K, Pullan RL, Rutazaana D, Sebuguzi CM, Opigo J, Kamya MR, Staedke SG, Dorsey G, Greenhouse B, Rodriguez-… -
Active Case Finding for Malaria: A 3-Year National Evaluation of Optimal Approaches to Detect Infections and Hotspots Through Reactive Case Detection in the Low-transmission Setting of Eswatini.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2020 Hsiang MS, Ntshalintshali N, Kang Dufour MS, Dlamini N, Nhlabathi N, Vilakati S, Malambe C, Zulu Z, Maphalala G, Novotny J, Murphy M, Schwartz A, Sturrock H, Gosling R, Dorsey G, Kunene S, Greenhouse … -
Associations between red blood cell variants and malaria among children and adults from three areas of Uganda: a prospective cohort study.
Malaria journal 2020 Kakande E, Greenhouse B, Bajunirwe F, Drakeley C, Nankabirwa JI, Walakira A, Nsobya SL, Katureebe A, Rek J, Arinaitwe E, Rosenthal PJ, Kamya MR, Dorsey G, Rodriguez-Barraquer I -
The Impact of Multiple Rounds of Indoor Residual Spraying on Malaria Incidence and Hemoglobin Levels in a High-Transmission Setting.
The Journal of infectious diseases 2020 Zinszer K, Charland K, Vahey S, Jahagirdar D, Rek JC, Arinaitwe E, Nankabirwa J, Morrison K, Sadoine ML, Tutt-Guérette MA, Staedke SG, Kamya MR, Greenhouse B, Rodriguez-Barraquer I, Dorsey G -
Study protocol for a cluster-randomized split-plot design trial to assess the effectiveness of targeted active malaria case detection among high-risk populations in Southern Lao PDR (the AcME-Lao study).
Gates open research 2019 Lover AA, Dantzer E, Hocini S, Estera R, Rerolle F, Smith JL, Hwang J, Gosling R, Yukich J, Greenhouse B, Jacobson J, Phetsouvanh R, Hongvanthong B, Bennett A -
High Genetic Diversity of Plasmodium falciparum in the Low-Transmission Setting of the Kingdom of Eswatini.
The Journal of infectious diseases 2019 Roh ME, Tessema SK, Murphy M, Nhlabathi N, Mkhonta N, Vilakati S, Ntshalintshali N, Saini M, Maphalala G, Chen A, Wilheim J, Prach L, Gosling R, Kunene S, S Hsiang M, Greenhouse B -
Applying next-generation sequencing to track falciparum malaria in sub-Saharan Africa.
Malaria journal 2019 Tessema SK, Raman J, Duffy CW, Ishengoma DS, Amambua-Ngwa A, Greenhouse B -
Pareto rules for malaria super-spreaders and super-spreading.
Nature communications 2019 Cooper L, Kang SY, Bisanzio D, Maxwell K, Rodriguez-Barraquer I, Greenhouse B, Drakeley C, Arinaitwe E, G Staedke S, Gething PW, Eckhoff P, Reiner RC, Hay SI, Dorsey G, Kamya MR, Lindsay SW, Grenfell … -
FLASH: a next-generation CRISPR diagnostic for multiplexed detection of antimicrobial resistance sequences.
Nucleic acids research 2019 Quan J, Langelier C, Kuchta A, Batson J, Teyssier N, Lyden A, Caldera S, McGeever A, Dimitrov B, King R, Wilheim J, Murphy M, Ares LP, Travisano KA, Sit R, Amato R, Mumbengegwi DR, Smith JL, Bennett A… -
Impact of Microscopic and Submicroscopic Parasitemia During Pregnancy on Placental Malaria in a High-Transmission Setting in Uganda.
The Journal of infectious diseases 2019 Briggs J, Ategeka J, Kajubi R, Ochieng T, Kakuru A, Ssemanda C, Wasswa R, Jagannathan P, Greenhouse B, Rodriguez-Barraquer I, Kamya M, Dorsey G -
Genetic Evidence of Focal Plasmodium falciparum Transmission in a Pre-elimination Setting in Southern Province, Zambia.
The Journal of infectious diseases 2019 Pringle JC, Tessema S, Wesolowski A, Chen A, Murphy M, Carpi G, Shields TM, Hamapumbu H, Searle KM, Kobayashi T, Katowa B, Musonda M, Stevenson JC, Thuma PE, Greenhouse B, Moss WJ, Norris DE -
Using parasite genetic and human mobility data to infer local and cross-border malaria connectivity in Southern Africa.
eLife 2019 Tessema S, Wesolowski A, Chen A, Murphy M, Wilheim J, Mupiri AR, Ruktanonchai NW, Alegana VA, Tatem AJ, Tambo M, Didier B, Cohen JM, Bennett A, Sturrock HJ, Gosling R, Hsiang MS, Smith DL, Mumbengegwi… -
Persistent Parasitemia Despite Dramatic Reduction in Malaria Incidence After 3 Rounds of Indoor Residual Spraying in Tororo, Uganda.
The Journal of infectious diseases 2019 Nankabirwa JI, Briggs J, Rek J, Arinaitwe E, Nayebare P, Katrak S, Staedke SG, Rosenthal PJ, Rodriguez-Barraquer I, Kamya MR, Dorsey G, Greenhouse B -
Priority use cases for antibody-detecting assays of recent malaria exposure as tools to achieve and sustain malaria elimination.
Gates open research 2019 Greenhouse B, Daily J, Guinovart C, Goncalves B, Beeson J, Bell D, Chang MA, Cohen JM, Ding X, Domingo G, Eisele TP, Lammie PJ, Mayor A, Merienne N, Monteiro W, Painter J, Rodriguez I, White M, … -
Simultaneous Quantification of Plasmodium Antigens and Host Factor C-Reactive Protein in Asymptomatic Individuals with Confirmed Malaria by Use of a Novel Multiplex Immunoassay.
Journal of clinical microbiology 2019 Jang IK, Tyler A, Lyman C, Kahn M, Kalnoky M, Rek JC, Arinaitwe E, Adrama H, Murphy M, Imwong M, Ling CL, Proux S, Haohankhunnatham W, Rist M, Seilie AM, Hanron A, Daza G, Chang M, Das S, Barney R, … -
Correction to: Mapping malaria by combining parasite genomic and epidemiologic data.
BMC medicine 2018 Wesolowski A, Taylor AR, Chang HH, Verity R, Tessema S, Bailey JA, Alex Perkins T, Neafsey DE, Greenhouse B, Buckee CO -
Subpatent malaria in a low transmission African setting: a cross-sectional study using rapid diagnostic testing (RDT) and loop-mediated isothermal amplification (LAMP) from Zambezi region, Namibia.
Malaria journal 2018 McCreesh P, Mumbengegwi D, Roberts K, Tambo M, Smith J, Whittemore B, Kelly G, Moe C, Murphy M, Chisenga M, Greenhouse B, Ntuku H, Kleinschmidt I, Sturrock H, Uusiku P, Gosling R, Bennett A, Hsiang MS -
Laboratory challenges of Plasmodium species identification in Aceh Province, Indonesia, a malaria elimination setting with newly discovered P. knowlesi.
PLoS neglected tropical diseases 2018 Coutrier FN, Tirta YK, Cotter C, Zarlinda I, González IJ, Schwartz A, Maneh C, Marfurt J, Murphy M, Herdiana H, Anstey NM, Greenhouse B, Hsiang MS, Noviyanti R -
Heterogeneous exposure and hotspots for malaria vectors at three study sites in Uganda.
Gates open research 2018 Kang SY, Battle KE, Gibson HS, Cooper LV, Maxwell K, Kamya M, Lindsay SW, Dorsey G, Greenhouse B, Rodriguez-Barraquer I, Reiner RCJ, Smith DL, Bisanzio D -
A new highly sensitive enzyme-linked immunosorbent assay for the detection of Plasmodium falciparum histidine-rich protein 2 in whole blood.
Malaria journal 2018 Jang IK, Das S, Barney RS, Peck RB, Rashid A, Proux S, Arinaitwe E, Rek J, Murphy M, Bowers K, Boadi S, Watson J, Nosten F, Greenhouse B, Chiodini PL, Domingo GJ -
Taking Sharper Pictures of Malaria with CAMERAs: Combined Antibodies to Measure Exposure Recency Assays.
The American journal of tropical medicine and hygiene 2018 Greenhouse B, Smith DL, Rodríguez-Barraquer I, Mueller I, Drakeley CJ -
Mapping malaria by combining parasite genomic and epidemiologic data.
BMC medicine 2018 Wesolowski A, Taylor AR, Chang HH, Verity R, Tessema S, Bailey JA, Alex Perkins T, Neafsey DE, Greenhouse B, Buckee CO -
Drug-Resistance and Population Structure of Plasmodium falciparum Across the Democratic Republic of Congo Using High-Throughput Molecular Inversion Probes.
The Journal of infectious diseases 2018 Aydemir O, Janko M, Hathaway NJ, Verity R, Mwandagalirwa MK, Tshefu AK, Tessema SK, Marsh PW, Tran A, Reimonn T, Ghani AC, Ghansah A, Juliano JJ, Greenhouse BR, Emch M, Meshnick SR, Bailey JA -
Quantification of anti-parasite and anti-disease immunity to malaria as a function of age and exposure.
eLife 2018 Rodriguez-Barraquer I, Arinaitwe E, Jagannathan P, Kamya MR, Rosenthal PJ, Rek J, Dorsey G, Nankabirwa J, Staedke SG, Kilama M, Drakeley C, Ssewanyana I, Smith DL, Greenhouse B -
Dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria during pregnancy and risk of malaria in early childhood: A randomized controlled trial.
PLoS medicine 2018 Jagannathan P, Kakuru A, Okiring J, Muhindo MK, Natureeba P, Nakalembe M, Opira B, Olwoch P, Nankya F, Ssewanyana I, Tetteh K, Drakeley C, Beeson J, Reiling L, Clark TD, Rodriguez-Barraquer I, … -
Antibody Profiling by Proteome Microarray with Multiplex Isotype Detection Reveals Overlap between Human and Aotus nancymaae Controlled Malaria Infections.
Proteomics 2018 Taghavian O, Jain A, Joyner CJ, Ketchum S, Nakajima R, Jasinskas A, Liang L, Fong R, King C, Greenhouse B, Murphy M, Bailey J, Galinski MR, Barnwell JW, Plowe CV, Davies DH, Felgner PL -
Elevated plasma abscisic acid is associated with asymptomatic falciparum malaria and with IgG-/caspase-1-dependent immunity in Plasmodium yoelii-infected mice.
Scientific reports 2018 Glennon EKK, Megawati D, Torrevillas BK, Ssewanyana I, Huang L, Aweeka F, Greenhouse B, Adams LG, Luckhart S -
Costs and cost-effectiveness of malaria reactive case detection using loop-mediated isothermal amplification compared to microscopy in the low transmission setting of Aceh Province, Indonesia.
Malaria journal 2018 Zelman BW, Baral R, Zarlinda I, Coutrier FN, Sanders KC, Cotter C, Herdiana H, Greenhouse B, Shretta R, Gosling RD, Hsiang MS -
Anatomy of a Hotspot: Chain and Seroepidemiology of Ebola Virus Transmission, Sukudu, Sierra Leone, 2015-16.
The Journal of infectious diseases 2018 Kelly JD, Barrie MB, Mesman AW, Karku S, Quiwa K, Drasher M, Schlough GW, Dierberg K, Koedoyoma S, Lindan CP, Jones JH, Chamie G, Worden L, Greenhouse B, Weiser SD, Porco TC, Rutherford GW, Richardson… -
Safety of Single-Dose Primaquine in G6PD-Deficient and G6PD-Normal Males in Mali Without Malaria: An Open-Label, Phase 1, Dose-Adjustment Trial.
The Journal of infectious diseases 2018 Chen I, Diawara H, Mahamar A, Sanogo K, Keita S, Kone D, Diarra K, Djimde M, Keita M, Brown J, Roh ME, Hwang J, Pett H, Murphy M, Niemi M, Greenhouse B, Bousema T, Gosling R, Dicko A -
Clinical consequences of submicroscopic malaria parasitaemia in Uganda.
Malaria journal 2018 Katrak S, Nayebare P, Rek J, Arinaitwe E, Nankabirwa JI, Kamya M, Dorsey G, Rosenthal PJ, Greenhouse B -
Study protocol for a cluster randomised controlled factorial design trial to assess the effectiveness and feasibility of reactive focal mass drug administration and vector control to reduce malaria transmission in the low endemic setting of Namibia.
BMJ open 2018 Medzihradsky OF, Kleinschmidt I, Mumbengegwi D, Roberts KW, McCreesh P, Dufour MK, Uusiku P, Katokele S, Bennett A, Smith J, Sturrock H, Prach LM, Ntuku H, Tambo M, Didier B, Greenhouse B, Gani Z, … -
Antibody Profiling by Proteome Microarray with Multiplex Isotype Detection Reveals Overlap between Human and Aotus nancymaae Controlled Malaria Infections.
Proteomics 2018 Taghavian O, Jain A, Joyner CJ, Ketchum S, Nakajima R, Jasinskas A, Liang L, Fong R, King C, Greenhouse B, Murphy M, Bailey J, Galinski MR, Barnwell JW, Plowe CV, Davies DH, Felgner PL -
Heterogeneous exposure and hotspots for malaria vectors at three study sites in Uganda.
Gates Open Research 2018 Su Yun Kang, Katherine E. Battle, Harry S. Gibson, Laura V. Cooper, Kilama Maxwell, Moses Kamya, Steven W. Lindsay, Grant Dorsey, Bryan Greenhouse, Isabel Rodriguez-Barraquer, Robert C. Jr. Reiner, … -
Reply to Rossi et al.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2017 Hsiang MS, Ranadive N, Chitundu S, Ntshalintshali N, Greenhouse B -
The Development of Plasmodium falciparum-Specific IL10 CD4 T Cells and Protection from Malaria in Children in an Area of High Malaria Transmission.
Frontiers in immunology 2017 Boyle MJ, Jagannathan P, Bowen K, McIntyre TI, Vance HM, Farrington LA, Schwartz A, Nankya F, Naluwu K, Wamala S, Sikyomu E, Rek J, Greenhouse B, Arinaitwe E, Dorsey G, Kamya MR, Feeney ME -
Performance of Loop-Mediated Isothermal Amplification for the Identification of Submicroscopic Plasmodium falciparum Infection in Uganda.
The American journal of tropical medicine and hygiene 2017 Katrak S, Murphy M, Nayebare P, Rek J, Smith M, Arinaitwe E, Nankabirwa JI, Kamya M, Dorsey G, Rosenthal PJ, Greenhouse B -
Quantification of anti-parasite and anti-disease immunity to malaria as a function of age and exposure
bioRxiv 2017 Rodriguez-Barraquer I, Arinaitwe E, Jagannathan P, Kamya M, Rosenthal P, Rek J, Dorsey G, Nankabirwa J, Staedke SG, Kilama M, Drakeley C, Ssewanyan I, Smith DL, Greenhouse B. -
Population genomics of virulence genes of Plasmodium falciparum in clinical isolates from Uganda.
Scientific reports 2017 Ruybal-Pesántez S, Tiedje KE, Tonkin-Hill G, Rask TS, Kamya MR, Greenhouse B, Dorsey G, Duffy MF, Day KP -
Vδ2+ T cell response to malaria correlates with protection from infection but is attenuated with repeated exposure.
Scientific reports 2017 Jagannathan P, Lutwama F, Boyle MJ, Nankya F, Farrington LA, McIntyre TI, Bowen K, Naluwu K, Nalubega M, Musinguzi K, Sikyomu E, Budker R, Katureebe A, Rek J, Greenhouse B, Dorsey G, Kamya MR, Feeney … -
Performance of a High-Sensitivity Rapid Diagnostic Test for Plasmodium falciparum Malaria in Asymptomatic Individuals from Uganda and Myanmar and Naive Human Challenge Infections.
The American journal of tropical medicine and hygiene 2017 Das S, Jang IK, Barney B, Peck R, Rek JC, Arinaitwe E, Adrama H, Murphy M, Imwong M, Ling CL, Proux S, Haohankhunnatham W, Rist M, Seilie AM, Hanron A, Daza G, Chang M, Nakamura T, Kalnoky M, Labarre … -
Multiplex, DNase-free one-step reverse transcription PCR for Plasmodium 18S rRNA and spliced gametocyte-specific mRNAs.
Malaria journal 2017 Hanron AE, Billman ZP, Seilie AM, Olsen TM, Fishbaugher M, Chang M, Rueckle T, Andenmatten N, Greenhouse B, Arinaitwe E, Rek J, Das S, Domingo GJ, Shipman K, Kappe SH, Kublin JG, Murphy SC -
Limitations of Rapid Diagnostic Testing in Patients with Suspected Malaria: A Diagnostic Accuracy Evaluation from Swaziland, a Low-Endemicity Country Aiming for Malaria Elimination.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2017 Ranadive N, Kunene S, Darteh S, Ntshalintshali N, Nhlabathi N, Dlamini N, Chitundu S, Saini M, Murphy M, Soble A, Schwartz A, Greenhouse B, Hsiang MS -
Low-Quality Housing Is Associated With Increased Risk of Malaria Infection: A National Population-Based Study From the Low Transmission Setting of Swaziland.
Open forum infectious diseases 2017 Dlamini N, Hsiang MS, Ntshalintshali N, Pindolia D, Allen R, Nhlabathi N, Novotny J, Kang Dufour MS, Midekisa A, Gosling R, LeMenach A, Cohen J, Dorsey G, Greenhouse B, Kunene S -
Drug resistance mediating Plasmodium falciparum polymorphisms and clinical presentations of parasitaemic children in Uganda.
Malaria journal 2017 Tukwasibwe S, Tumwebaze P, Conrad M, Arinaitwe E, Kamya MR, Dorsey G, Nsobya SL, Greenhouse B, Rosenthal PJ -
Changing Antimalarial Drug Resistance Patterns Identified by Surveillance at Three Sites in Uganda.
The Journal of infectious diseases 2017 Tumwebaze P, Tukwasibwe S, Taylor A, Conrad M, Ruhamyankaka E, Asua V, Walakira A, Nankabirwa J, Yeka A, Staedke SG, Greenhouse B, Nsobya SL, Kamya MR, Dorsey G, Rosenthal PJ -
Avidity of anti-malarial antibodies inversely related to transmission intensity at three sites in Uganda.
Malaria journal 2017 Ssewanyana I, Arinaitwe E, Nankabirwa JI, Yeka A, Sullivan R, Kamya MR, Rosenthal PJ, Dorsey G, Mayanja-Kizza H, Drakeley C, Greenhouse B, Tetteh KK -
THE REAL McCOIL: A method for the concurrent estimation of the complexity of infection and SNP allele frequency for malaria parasites.
PLoS computational biology 2017 Chang HH, Worby CJ, Yeka A, Nankabirwa J, Kamya MR, Staedke SG, Dorsey G, Murphy M, Neafsey DE, Jeffreys AE, Hubbart C, Rockett KA, Amato R, Kwiatkowski DP, Buckee CO, Greenhouse B -
Spatio-temporal analysis of malaria vector density from baseline through intervention in a high transmission setting.
Parasites & vectors 2016 Alegana VA, Kigozi SP, Nankabirwa J, Arinaitwe E, Kigozi R, Mawejje H, Kilama M, Ruktanonchai NW, Ruktanonchai CW, Drakeley C, Lindsay SW, Greenhouse B, Kamya MR, Smith DL, Atkinson PM, Dorsey G, … -
Measures of Malaria Burden after Long-Lasting Insecticidal Net Distribution and Indoor Residual Spraying at Three Sites in Uganda: A Prospective Observational Study.
PLoS medicine 2016 Katureebe A, Zinszer K, Arinaitwe E, Rek J, Kakande E, Charland K, Kigozi R, Kilama M, Nankabirwa J, Yeka A, Mawejje H, Mpimbaza A, Katamba H, Donnelly MJ, Rosenthal PJ, Drakeley C, Lindsay SW, … -
Quantitative, model-based estimates of variability in the generation and serial intervals of Plasmodium falciparum malaria.
Malaria journal 2016 Huber JH, Johnston GL, Greenhouse B, Smith DL, Perkins TA -
Characterizing microscopic and submicroscopic malaria parasitaemia at three sites with varied transmission intensity in Uganda.
Malaria journal 2016 Rek J, Katrak S, Obasi H, Nayebare P, Katureebe A, Kakande E, Arinaitwe E, Nankabirwa JI, Jagannathan P, Drakeley C, Staedke SG, Smith DL, Bousema T, Kamya M, Rosenthal PJ, Dorsey G, Greenhouse B -
Malaria risk factor assessment using active and passive surveillance data from Aceh Besar, Indonesia, a low endemic, malaria elimination setting with Plasmodium knowlesi, Plasmodium vivax, and Plasmodium falciparum.
Malaria journal 2016 Herdiana H, Cotter C, Coutrier FN, Zarlinda I, Zelman BW, Tirta YK, Greenhouse B, Gosling RD, Baker P, Whittaker M, Hsiang MS -
Reductions in malaria in pregnancy and adverse birth outcomes following indoor residual spraying of insecticide in Uganda.
Malaria journal 2016 Muhindo MK, Kakuru A, Natureeba P, Awori P, Olwoch P, Ategeka J, Nayebare P, Clark TD, Muehlenbachs A, Roh M, Mpeka B, Greenhouse B, Havlir DV, Kamya MR, Dorsey G, Jagannathan P -
Evaluating the epidemiology of P. falciparum parasitemia in three areas of Uganda with different transmission intensities.
Annals of Global Health 2016 H. Obasi, J. Rek, P. Nayebare, A. Katureeba, E. Kakande, E. Arinaitwe, S. Staedke, M. Kamya, S. Katrak, P. Jagannathan, G. Dorsey, B. Greenhouse -
Housing quality as a potential risk factor for locally acquired malaria infection in Swaziland.
Annals of Global Health 2016 N. Mkhonta, R. Allen, D. Pindolia, N. Ntshalintshali, J. Novotny, M. Kang Dufour, R. Gosling, A. LeMenach, J. Cohen, A. Midekisa, B. Greenhouse, M.S. Hsiang, S. Kunene -
Quantifying Heterogeneous Malaria Exposure and Clinical Protection in a Cohort of Ugandan Children.
The Journal of infectious diseases 2016 Rodriguez-Barraquer I, Arinaitwe E, Jagannathan P, Boyle MJ, Tappero J, Muhindo M, Kamya MR, Dorsey G, Drakeley C, Ssewanyana I, Smith DL, Greenhouse B -
Spatiotemporal Analysis of Malaria in Urban Ahmedabad (Gujarat), India: Identification of Hot Spots and Risk Factors for Targeted Intervention.
The American journal of tropical medicine and hygiene 2016 Parizo J, Sturrock HJ, Dhiman RC, Greenhouse B -
Mapping Malaria Risk in Low Transmission Settings: Challenges and Opportunities.
Trends in parasitology 2016 Sturrock HJW, Bennett AF, Midekisa A, Gosling RD, Gething PW, Greenhouse B -
Effective Antimalarial Chemoprevention in Childhood Enhances the Quality of CD4+ T Cells and Limits Their Production of Immunoregulatory Interleukin 10.
The Journal of infectious diseases 2016 Jagannathan P, Bowen K, Nankya F, McIntyre TI, Auma A, Wamala S, Sikyomu E, Naluwu K, Nalubega M, Boyle MJ, Farrington LA, Bigira V, Kapisi J, Aweeka F, Greenhouse B, Kamya M, Dorsey G, Feeney ME -
B cell sub-types following acute malaria and associations with clinical immunity.
Malaria journal 2016 Sullivan RT, Ssewanyana I, Wamala S, Nankya F, Jagannathan P, Tappero JW, Mayanja-Kizza H, Muhindo MK, Arinaitwe E, Kamya M, Dorsey G, Feeney ME, Riley EM, Drakeley CJ, Greenhouse B, Sullivan R -
Community-wide Prevalence of Malaria Parasitemia in HIV-Infected and Uninfected Populations in a High-Transmission Setting in Uganda.
The Journal of infectious diseases 2016 Katrak S, Day N, Ssemmondo E, Kwarisiima D, Midekisa A, Greenhouse B, Kamya M, Havlir D, Dorsey G -
Estimating malaria parasite prevalence from community surveys in Uganda: a comparison of microscopy, rapid diagnostic tests and polymerase chain reaction.
Malaria journal 2015 Nankabirwa JI, Yeka A, Arinaitwe E, Kigozi R, Drakeley C, Kamya MR, Greenhouse B, Rosenthal PJ, Dorsey G, Staedke SG -
Mapping residual transmission for malaria elimination.
eLife 2015 Reiner RC, Le Menach A, Kunene S, Ntshalintshali N, Hsiang MS, Perkins TA, Greenhouse B, Tatem AJ, Cohen JM, Smith DL -
Clinical determinants of early parasitological response to ACTs in African patients with uncomplicated falciparum malaria: a literature review and meta-analysis of individual patient data.
BMC medicine 2015 WWARN Artemisinin based Combination Therapy (ACT) Africa Baseline Study Group, Dahal P, d'Alessandro U, Dorsey G, Guerin PJ, Nsanzabana C, Price RN, Sibley CH, Stepniewska K, Talisuna AO -
Biosignatures of Exposure/Transmission and Immunity.
The American journal of tropical medicine and hygiene 2015 King CL, Davies DH, Felgner P, Baum E, Jain A, Randall A, Tetteh K, Drakeley CJ, Greenhouse B -
Malaria Molecular Epidemiology: Lessons from the International Centers of Excellence for Malaria Research Network.
The American journal of tropical medicine and hygiene 2015 Escalante AA, Ferreira MU, Vinetz JM, Volkman SK, Cui L, Gamboa D, Krogstad DJ, Barry AE, Carlton JM, van Eijk AM, Pradhan K, Mueller I, Greenhouse B, Pacheco MA, Vallejo AF, Herrera S, Felger I -
Novel serologic biomarkers provide accurate estimates of recent Plasmodium falciparum exposure for individuals and communities.
Proceedings of the National Academy of Sciences of the United States of America 2015 Helb DA, Tetteh KK, Felgner PL, Skinner J, Hubbard A, Arinaitwe E, Mayanja-Kizza H, Ssewanyana I, Kamya MR, Beeson JG, Tappero J, Smith DL, Crompton PD, Rosenthal PJ, Dorsey G, Drakeley CJ, Greenhouse… -
Decline of FoxP3+ Regulatory CD4 T Cells in Peripheral Blood of Children Heavily Exposed to Malaria.
PLoS pathogens 2015 Boyle MJ, Jagannathan P, Farrington LA, Eccles-James I, Wamala S, McIntyre TI, Vance HM, Bowen K, Nankya F, Auma A, Nalubega M, Sikyomu E, Naluwu K, Rek J, Katureebe A, Bigira V, Kapisi J, Tappero J, … -
Malaria genotyping for epidemiologic surveillance.
Proceedings of the National Academy of Sciences of the United States of America 2015 Greenhouse B, Smith DL -
FCRL5 Delineates Functionally Impaired Memory B Cells Associated with Plasmodium falciparum Exposure.
PLoS pathogens 2015 Sullivan RT, Kim CC, Fontana MF, Feeney ME, Jagannathan P, Boyle MJ, Drakeley CJ, Ssewanyana I, Nankya F, Mayanja-Kizza H, Dorsey G, Greenhouse B -
Characterising temporal trends in asymptomatic Plasmodium infections and transporter polymorphisms during transition from high to low transmission in Zanzibar, 2005-2013.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2015 Morris U, Xu W, Msellem MI, Schwartz A, Abass A, Shakely D, Cook J, Bhattarai A, Petzold M, Greenhouse B, Ali AS, Björkman A, Fröberg G, Mårtensson A -
Poor housing construction associated with increased malaria incidence in a cohort of young Ugandan children.
The American journal of tropical medicine and hygiene 2015 Snyman K, Mwangwa F, Bigira V, Kapisi J, Clark TD, Osterbauer B, Greenhouse B, Sturrock H, Gosling R, Liu J, Dorsey G -
Malaria transmission, infection, and disease at three sites with varied transmission intensity in Uganda: implications for malaria control.
The American journal of tropical medicine and hygiene 2015 Kamya MR, Arinaitwe E, Wanzira H, Katureebe A, Barusya C, Kigozi SP, Kilama M, Tatem AJ, Rosenthal PJ, Drakeley C, Lindsay SW, Staedke SG, Smith DL, Greenhouse B, Dorsey G -
Factors associated with malaria parasitemia, anemia and serological responses in a spectrum of epidemiological settings in Uganda.
PloS one 2015 Yeka A, Nankabirwa J, Mpimbaza A, Kigozi R, Arinaitwe E, Drakeley C, Greenhouse B, Kamya MR, Dorsey G, Staedke SG -
Impact of antimalarial treatment and chemoprevention on the drug sensitivity of malaria parasites isolated from ugandan children.
Antimicrobial agents and chemotherapy 2015 Tumwebaze P, Conrad MD, Walakira A, LeClair N, Byaruhanga O, Nakazibwe C, Kozak B, Bloome J, Okiring J, Kakuru A, Bigira V, Kapisi J, Legac J, Gut J, Cooper RA, Kamya MR, Havlir DV, Dorsey G, … -
The Effect of Storage and Extraction Methods on Amplification of Plasmodium falciparum DNA from Dried Blood Spots.
The American journal of tropical medicine and hygiene 2015 Schwartz A, Baidjoe A, Rosenthal PJ, Dorsey G, Bousema T, Greenhouse B -
Effector Phenotype of Plasmodium falciparum-Specific CD4+ T Cells Is Influenced by Both Age and Transmission Intensity in Naturally Exposed Populations.
The Journal of infectious diseases 2015 Boyle MJ, Jagannathan P, Bowen K, McIntyre TI, Vance HM, Farrington LA, Greenhouse B, Nankya F, Rek J, Katureebe A, Arinaitwe E, Dorsey G, Kamya MR, Feeney ME -
Reply to Goyal et al.
The Journal of infectious diseases 2014 Hsiang MS, Greenhouse B, Rosenthal PJ -
The path of least resistance: aggressive or moderate treatment?
Proceedings. Biological sciences 2014 Kouyos RD, Metcalf CJ, Birger R, Klein EY, Abel zur Wiesch P, Ankomah P, Arinaminpathy N, Bogich TL, Bonhoeffer S, Brower C, Chi-Johnston G, Cohen T, Day T, Greenhouse B, Huijben S, Metlay J, Mideo N,… -
Loss and dysfunction of Vδ2⁺ γδ T cells are associated with clinical tolerance to malaria.
Science translational medicine 2014 Jagannathan P, Kim CC, Greenhouse B, Nankya F, Bowen K, Eccles-James I, Muhindo MK, Arinaitwe E, Tappero JW, Kamya MR, Dorsey G, Feeney ME -
Temporal changes in prevalence of molecular markers mediating antimalarial drug resistance in a high malaria transmission setting in Uganda.
The American journal of tropical medicine and hygiene 2014 Mbogo GW, Nankoberanyi S, Tukwasibwe S, Baliraine FN, Nsobya SL, Conrad MD, Arinaitwe E, Kamya M, Tappero J, Staedke SG, Dorsey G, Greenhouse B, Rosenthal PJ -
Point of care testing for malaria using LAMP, loop mediated isothermal amplification.
The Journal of infectious diseases 2014 Hsiang MS, Greenhouse B, Rosenthal PJ -
A micro-epidemiological analysis of febrile malaria in Coastal Kenya showing hotspots within hotspots.
eLife 2014 Bejon P, Williams TN, Nyundo C, Hay SI, Benz D, Gething PW, Otiende M, Peshu J, Bashraheil M, Greenhouse B, Bousema T, Bauni E, Marsh K, Smith DL, Borrmann S -
Estimating the annual entomological inoculation rate for Plasmodium falciparum transmitted by Anopheles gambiae s.l. using three sampling methods in three sites in Uganda.
Malaria journal 2014 Kilama M, Smith DL, Hutchinson R, Kigozi R, Yeka A, Lavoy G, Kamya MR, Staedke SG, Donnelly MJ, Drakeley C, Greenhouse B, Dorsey G, Lindsay SW -
Comparative impacts over 5 years of artemisinin-based combination therapies on Plasmodium falciparum polymorphisms that modulate drug sensitivity in Ugandan children.
The Journal of infectious diseases 2014 Conrad MD, LeClair N, Arinaitwe E, Wanzira H, Kakuru A, Bigira V, Muhindo M, Kamya MR, Tappero JW, Greenhouse B, Dorsey G, Rosenthal PJ -
IFNγ/IL-10 co-producing cells dominate the CD4 response to malaria in highly exposed children.
PLoS pathogens 2014 Jagannathan P, Eccles-James I, Bowen K, Nankya F, Auma A, Wamala S, Ebusu C, Muhindo MK, Arinaitwe E, Briggs J, Greenhouse B, Tappero JW, Kamya MR, Dorsey G, Feeney ME -
Biochemical and immunological mechanisms by which sickle cell trait protects against malaria.
Malaria journal 2013 Gong L, Parikh S, Rosenthal PJ, Greenhouse B -
The usefulness of rapid diagnostic tests in the new context of low malaria transmission in Zanzibar.
PloS one 2013 Shakely D, Elfving K, Aydin-Schmidt B, Msellem MI, Morris U, Omar R, Weiping X, Petzold M, Greenhouse B, Baltzell KA, Ali AS, Björkman A, Mårtensson A -
Epidemiology of subpatent Plasmodium falciparum infection: implications for detection of hotspots with imperfect diagnostics.
Malaria journal 2013 Mosha JF, Sturrock HJ, Greenhouse B, Greenwood B, Sutherland CJ, Gadalla N, Atwal S, Drakeley C, Kibiki G, Bousema T, Chandramohan D, Gosling R -
Fitness Consequences of Plasmodium falciparum pfmdr1 Polymorphisms Inferred from Ex Vivo Culture of Ugandan Parasites.
Antimicrobial agents and chemotherapy 2013 Ochong E, Tumwebaze PK, Byaruhanga O, Greenhouse B, Rosenthal PJ -
Targeting asymptomatic malaria infections: active surveillance in control and elimination.
PLoS medicine 2013 Sturrock HJ, Hsiang MS, Cohen JM, Smith DL, Greenhouse B, Bousema T, Gosling RD -
Reactive case detection for malaria elimination: real-life experience from an ongoing program in Swaziland.
PloS one 2013 Sturrock HJ, Novotny JM, Kunene S, Dlamini S, Zulu Z, Cohen JM, Hsiang MS, Greenhouse B, Gosling RD -
Increasing incidence of malaria in children despite insecticide-treated bed nets and prompt anti-malarial therapy in Tororo, Uganda.
Malaria journal 2012 Jagannathan P, Muhindo MK, Kakuru A, Arinaitwe E, Greenhouse B, Tappero J, Rosenthal PJ, Kaharuza F, Kamya MR, Dorsey G -
Associations between antibodies to a panel of Plasmodium falciparum specific antigens and response to sub-optimal antimalarial therapy in Kampala, Uganda.
PloS one 2012 Keh CE, Jha AR, Nzarubara B, Lanar DE, Dutta S, Theisen M, Rosenthal PJ, Dorsey G, Nixon DF, Greenhouse B -
Prevalence of PCR detectable malaria infection among febrile patients with a negative Plasmodium falciparum specific rapid diagnostic test in Zanzibar.
The American journal of tropical medicine and hygiene 2012 Baltzell KA, Shakely D, Hsiang M, Kemere J, Ali AS, Björkman A, Mårtensson A, Omar R, Elfving K, Msellem M, Aydin-Schmidt B, Rosenthal PJ, Greenhouse B -
Evidence for both innate and acquired mechanisms of protection from Plasmodium falciparum in children with sickle cell trait.
Blood 2012 Gong L, Maiteki-Sebuguzi C, Rosenthal PJ, Hubbard AE, Drakeley CJ, Dorsey G, Greenhouse B -
Surveillance for malaria elimination in Swaziland: a national cross-sectional study using pooled PCR and serology.
PloS one 2012 Hsiang MS, Hwang J, Kunene S, Drakeley C, Kandula D, Novotny J, Parizo J, Jensen T, Tong M, Kemere J, Dlamini S, Moonen B, Angov E, Dutta S, Ockenhouse C, Dorsey G, Greenhouse B -
Antibodies to Plasmodium falciparum antigens predict a higher risk of malaria but protection from symptoms once parasitemic.
The Journal of infectious diseases 2011 Greenhouse B, Ho B, Hubbard A, Njama-Meya D, Narum DL, Lanar DE, Dutta S, Rosenthal PJ, Dorsey G, John CC -
Limited ability of Plasmodium falciparum pfcrt, pfmdr1, and pfnhe1 polymorphisms to predict quinine in vitro sensitivity or clinical effectiveness in Uganda.
Antimicrobial agents and chemotherapy 2010 Baliraine FN, Nsobya SL, Achan J, Tibenderana JK, Talisuna AO, Greenhouse B, Rosenthal PJ -
PCR-based pooling of dried blood spots for detection of malaria parasites: optimization and application to a cohort of Ugandan children.
Journal of clinical microbiology 2010 Hsiang MS, Lin M, Dokomajilar C, Kemere J, Pilcher CD, Dorsey G, Greenhouse B -
Incidence of malaria and efficacy of combination antimalarial therapies over 4 years in an urban cohort of Ugandan children.
PloS one 2010 Clark TD, Njama-Meya D, Nzarubara B, Maiteki-Sebuguzi C, Greenhouse B, Staedke SG, Kamya MR, Dorsey G, Rosenthal PJ -
Selection of known Plasmodium falciparum resistance-mediating polymorphisms by artemether-lumefantrine and amodiaquine-sulfadoxine-pyrimethamine but not dihydroartemisinin-piperaquine in Burkina Faso.
Antimicrobial agents and chemotherapy 2010 Somé AF, Séré YY, Dokomajilar C, Zongo I, Rouamba N, Greenhouse B, Ouédraogo JB, Rosenthal PJ -
Gel versus capillary electrophoresis genotyping for categorizing treatment outcomes in two anti-malarial trials in Uganda.
Malaria journal 2010 Gupta V, Dorsey G, Hubbard AE, Rosenthal PJ, Greenhouse B -
In vitro sensitivities of Plasmodium falciparum to different antimalarial drugs in Uganda.
Antimicrobial agents and chemotherapy 2010 Nsobya SL, Kiggundu M, Nanyunja S, Joloba M, Greenhouse B, Rosenthal PJ -
Artemether-lumefantrine versus dihydroartemisinin-piperaquine for falciparum malaria: a longitudinal, randomized trial in young Ugandan children.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2009 Arinaitwe E, Sandison TG, Wanzira H, Kakuru A, Homsy J, Kalamya J, Kamya MR, Vora N, Greenhouse B, Rosenthal PJ, Tappero J, Dorsey G -
Decreasing efficacy of antimalarial combination therapy in Uganda is explained by decreasing host immunity rather than increasing drug resistance.
The Journal of infectious diseases 2009 Greenhouse B, Slater M, Njama-Meya D, Nzarubara B, Maiteki-Sebuguzi C, Clark TD, Staedke SG, Kamya MR, Hubbard A, Rosenthal PJ, Dorsey G -
Factors determining the heterogeneity of malaria incidence in children in Kampala, Uganda.
The Journal of infectious diseases 2008 Clark TD, Greenhouse B, Njama-Meya D, Nzarubara B, Maiteki-Sebuguzi C, Staedke SG, Seto E, Kamya MR, Rosenthal PJ, Dorsey G -
Impact of transmission intensity on the accuracy of genotyping to distinguish recrudescence from new infection in antimalarial clinical trials.
Antimicrobial agents and chemotherapy 2007 Greenhouse B, Dokomajilar C, Hubbard A, Rosenthal PJ, Dorsey G -
Artemether-lumefantrine versus dihydroartemisinin-piperaquine for treatment of malaria: a randomized trial.
PLoS clinical trials 2007 Kamya MR, Yeka A, Bukirwa H, Lugemwa M, Rwakimari JB, Staedke SG, Talisuna AO, Greenhouse B, Nosten F, Rosenthal PJ, Wabwire-Mangen F, Dorsey G -
Hepatotoxicity due to a drug interaction between amodiaquine plus artesunate and efavirenz.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2007 German P, Greenhouse B, Coates C, Dorsey G, Rosenthal PJ, Charlebois E, Lindegardh N, Havlir D, Aweeka FT -
The use of genotyping in antimalarial clinical trials: a systematic review of published studies from 1995-2005.
Malaria journal 2006 Collins WJ, Greenhouse B, Rosenthal PJ, Dorsey G -
Validation of microsatellite markers for use in genotyping polyclonal Plasmodium falciparum infections.
The American journal of tropical medicine and hygiene 2006 Greenhouse B, Myrick A, Dokomajilar C, Woo JM, Carlson EJ, Rosenthal PJ, Dorsey G -
Selection of Plasmodium falciparum pfmdr1 alleles following therapy with artemether-lumefantrine in an area of Uganda where malaria is highly endemic.
Antimicrobial agents and chemotherapy 2006 Dokomajilar C, Nsobya SL, Greenhouse B, Rosenthal PJ, Dorsey G -
Urban malaria: primary caregivers' knowledge, attitudes, practices and predictors of malaria incidence in a cohort of Ugandan children.
Tropical medicine & international health : TM & IH 2003 Njama D, Dorsey G, Guwatudde D, Kigonya K, Greenhouse B, Musisi S, Kamya MR -
Recombinant glycoprotein vaccines for human immunodeficiency virus-infected children and their effects on viral quasispecies.
Clinical and diagnostic laboratory immunology 2002 Essajee SM, Yogev R, Pollack H, Greenhouse B, Krasinski K, Borkowsky W