Bridget Ostrem, MD, PhD
Assistant Professor
Neurology
School of Medicine
Dr. Ostrem has expertise in Maternal-Fetal and Neonatal Neurology and treats babies, children, young adults, and pregnant patients with neurological symptoms and disorders. She completed her M.D. and Ph.D. at UCSF followed by residency in Pediatric Neurology in the Mass General Brigham (Partners Neurology) Program in Boston, Massachusetts, and clinical fellowship in Women's Neurology at Brigham and Women's Hospital.
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She also completed a postdoctoral fellowship in the laboratory of Dr. Paola Arlotta at Harvard. Dr. Ostrem's research focuses on developing novel strategies for neuroprotection and repair in the fetal and neonatal brain, and understanding how maternal factors impact brain development.
Awards
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- NIH-NINDS CNCDP K12 Award, UCSF, 2022
- NIH-NINDS R25 Award, MGH, 2020-2022
- Alpha Omega Alpha Honor Medical Society Awardee, UCSF, 2016
- California Institute of Regenerative Medicine Predoctoral Grant, UCSF, 2012-2014
Education & Training
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- Women's Neurology Fellowship Brigham and Women's Hospital 06/2021
- Neurology with Special Qualification in Child Neurology Partners Neurology Residency 06/2020
- MD Medicine UCSF 06/2016
- PhD Neuroscience UCSF 03/2014
Websites
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- Ostrem Lab Website (theostremlab.ucsf.edu)
Publications (16)
Top publication keywords:
NeocortexNeurodevelopmental DisordersStrokeCentral Nervous System Viral DiseasesInflammationNeurogenesisPoly I-CAcetylcysteineCerebrovascular DisordersMitosisIschemic Attack, TransientMicrogliaNeural Stem CellsVascular MalformationsNeuroglia
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ECI biocommentary: Bridget Ostrem.
Pediatric research 2024 Ostrem BEL -
Minimum effective dose of clemastine in a mouse model of preterm white matter injury.
Pediatric research 2024 Odell EP, Jabassini N, Schniedewind B, Pease-Raissi SE, Frymoyer A, Christians U, Green AJ, Chan JR, Ostrem BEL -
Fetal brain response to maternal inflammation requires microglia.
Development (Cambridge, England) 2024 Ostrem BEL, Domínguez-Iturza N, Stogsdill JA, Faits T, Kim K, Levin JZ, Arlotta P -
Minimum Effective Dose of Clemastine in a Mouse Model of Preterm White Matter Injury.
bioRxiv : the preprint server for biology 2024 Odell E, Jabassini N, Schniedewind B, Pease-Raissi SE, Frymoyer A, Christians U, Green AJ, Chan JR, Ostrem BEL -
Monogenic Causes of Cerebrovascular Disease in Childhood: A Case Series.
Pediatric neurology 2023 Ostrem BEL, Godfrey D, Caruso PA, Musolino PL
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Acquired Brain Injuries Across the Perinatal Spectrum: Pathophysiology and Emerging Therapies.
Pediatric neurology 2023 Russ JB, Ostrem BEL -
Inflammatory Activity After Diverse Fertility Treatments: A Multicenter Analysis in the Modern Multiple Sclerosis Treatment Era.
Neurology(R) neuroimmunology & neuroinflammation 2023 Graham EL, Bakkensen JB, Anderson A, Lancki N, Davidson A, Perez Giraldo G, Jungheim ES, Vanderhoff AC, Ostrem B, Mok-Lin E, Huang D, Bevan CJ, Jacobs D, Kaplan TB, Houtchens MK, Bove R -
Peripartum disease activity in moderately and severely disabled women with multiple sclerosis.
Multiple sclerosis journal - experimental, translational and clinical 2022 Ostrem BL, Anderson A, Conway S, Healy BC, Oh J, Jacobs D, Dobson R, Graham EL, Sadovnick AD, Zimmerman V, Liu Y, Bove R, Houtchens M -
Enhanced Virus Detection and Metagenomic Sequencing in Patients with Meningitis and Encephalitis.
mBio 2021 Piantadosi A, Mukerji SS, Ye S, Leone MJ, Freimark LM, Park D, Adams G, Lemieux J, Kanjilal S, Solomon IH, Ahmed AA, Goldstein R, Ganesh V, Ostrem B, Cummins KC, Thon JM, Kinsella CM, Rosenberg E, … -
De Novo Variants in the ATPase Module of MORC2 Cause a Neurodevelopmental Disorder with Growth Retardation and Variable Craniofacial Dysmorphism.
American journal of human genetics 2020 Guillen Sacoto MJ, Tchasovnikarova IA, Torti E, Forster C, Andrew EH, Anselm I, Baranano KW, Briere LC, Cohen JS, Craigen WJ, Cytrynbaum C, Ekhilevitch N, Elrick MJ, Fatemi A, Fraser JL, Gallagher RC,… -
oRGs and mitotic somal translocation - a role in development and disease.
Current opinion in neurobiology 2016 Ostrem B, Di Lullo E, Kriegstein A -
Control of outer radial glial stem cell mitosis in the human brain.
Cell reports 2014 Ostrem BE, Lui JH, Gertz CC, Kriegstein AR -
Diverse behaviors of outer radial glia in developing ferret and human cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Gertz CC, Lui JH, LaMonica BE, Wang X, Kriegstein AR -
Mitotic spindle orientation predicts outer radial glial cell generation in human neocortex.
Nature communications 2013 LaMonica BE, Lui JH, Hansen DV, Kriegstein AR -
OSVZ progenitors in the human cortex: an updated perspective on neurodevelopmental disease.
Current opinion in neurobiology 2012 LaMonica BE, Lui JH, Wang X, Kriegstein AR -
A new subtype of progenitor cell in the mouse embryonic neocortex.
Nature neuroscience 2011 Wang X, Tsai JW, LaMonica B, Kriegstein AR