Brian Graham, MD
Professor
Medicine
School of Medicine

I am the Division Chief of Pulmonary and Critical Care Medicine at Zuckerberg San Francisco General Hospital, and a Professor in Residence at UCSF. My primary clinical and research interest is in pulmonary hypertension. I particularly study schistosomiasis associated pulmonary hypertension, a common cause worldwide.

Awards

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• John F. Murray, MD Distinguished Professorship in Pulmonary Medicine, UCSF, 2020
• Jo Rae Wright Award for Scientific Excellence, Parker B Francis Foundation, 2016

Education & Training

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• Diversity, Equity and Inclusion Training University of California 2021
• Pulmonary-Critical Care Fellowship University of Colorado 06/2010
• Internal Medicine Residency University of Colorado 06/2007
• MD Medicine Harvard 06/2004
• MEng Electrical Engineering MIT 06/2000
• SB Electrical Engineering MIT 06/2000

Interests

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• Pulmonary medicine
• Schistosomiasis
• Critical care medicine
• Pulmonary hypertension

Websites

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• Graham Laboratory Website (grahamlab.ucsf.edu)

Grants and Projects

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• Complement Mediated Remodeling in Pulmonary Vascular Disease, NIH, 2020-2025
• Activation, Phenotype and Function of CD4 T Cells in Schistosoma-Pulmonary Hypertension, NIH, 2016-2021
• Role of Th2 CD4 T Cells in Schistosoma Pulmonary Hypertension, NIH, 2016-2019
• Schistosomiasis Associated Pulmonary Arterial Hypertension, NIH, 2011-2017

Publications (91)

Top publication keywords:
Bone Morphogenetic Protein Receptors, Type IISchistosomaSchistosomiasisHypoxiaPulmonary ArteryMyocytes, Smooth MuscleTh2 CellsSchistosoma japonicumThrombospondin 1Hypertension, PulmonarySchistosoma mansoniHeart VentriclesSchistosomiasis mansoniFamilial Primary Pulmonary HypertensionTransforming Growth Factor beta

• Experimental Schistosoma japonicum-induced pulmonary hypertension.
  PLoS neglected tropical diseases 2022 Kassa B, Lee MH, Kumar R, Mickael C, Sanders L, Tuder RM, Mentink-Kane M, Graham BB
• Schistosomiasis Pulmonary Arterial Hypertension.
  Frontiers in immunology 2020 Sibomana JP, Campeche A, Carvalho-Filho RJ, Correa RA, Duani H, Pacheco Guimaraes V, Hilton JF, Kassa B, Kumar R, Lee MH, Loureiro CMC, Mazimba S, Mickael C, Oliveira RKF, Ota-Arakaki JS, Rezende CF, …
• Interstitial macrophage-derived thrombospondin-1 contributes to hypoxia-induced pulmonary hypertension.
  Cardiovascular research 2020 Kumar R, Mickael C, Kassa B, Sanders L, Hernandez-Saavedra D, Koyanagi DE, Kumar S, Pugliese SC, Thomas S, McClendon J, Maloney JP, Janssen WJ, Stenmark KR, Tuder RM, Graham BB
• Publisher Correction: Stable isotope metabolomics of pulmonary artery smooth muscle and endothelial cells in pulmonary hypertension and with TGF-beta treatment.
  Scientific reports 2020 Hernandez-Saavedra D, Sanders L, Freeman S, Reisz JA, Lee MH, Mickael C, Kumar R, Kassa B, Gu S, D' Alessandro A, Stenmark KR, Tuder RM, Graham BB
• Th2 CD4+ T Cells Are Necessary and Sufficient for Schistosoma-Pulmonary Hypertension.
  Journal of the American Heart Association 2019 Kumar R, Mickael C, Kassa B, Sanders L, Koyanagi D, Hernandez-Saavedra D, Freeman S, Morales-Cano D, Cogolludo A, McKee AS, Fontenot AP, Butrous G, Tuder RM, Graham BB
• IL-6Ra in Smooth Muscle Cells Protects against Schistosoma- and Hypoxia-induced Pulmonary Hypertension.
  American journal of respiratory cell and molecular biology 2019 Mickael C, Kumar R, Hernandez-Saavedra D, Kassa B, Sanders L, Koyanagi D, Gu S, Lee MH, Tuder RM, Graham BB
• Vascular Adaptation of the Right Ventricle in Experimental Pulmonary Hypertension.
  American journal of respiratory cell and molecular biology 2018 Graham BB, Kumar R, Mickael C, Kassa B, Koyanagi D, Sanders L, Zhang L, Perez M, Hernandez-Saavedra D, Valencia C, Dixon K, Harral J, Loomis Z, Irwin D, Nemkov T, D'Alessandro A, Stenmark KR, Tuder RM
• Right Ventricle Vasculature in Human Pulmonary Hypertension Assessed by Stereology.
  American journal of respiratory and critical care medicine 2017 Graham BB, Koyanagi D, Kandasamy B, Tuder RM
• The Causal Role of IL-4 and IL-13 in Schistosoma mansoni Pulmonary Hypertension.
  American journal of respiratory and critical care medicine 2015 Kumar R, Mickael C, Chabon J, Gebreab L, Rutebemberwa A, Garcia AR, Koyanagi DE, Sanders L, Gandjeva A, Kearns MT, Barthel L, Janssen WJ, Mauad T, Bandeira A, Schmidt E, Tuder RM, Graham BB

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• Hypobaric hypoxia modulated structural characteristics of circulating cell-free DNA in high-altitude pulmonary edema.
  American journal of physiology. Lung cellular and molecular physiology 2024 Ali M, Choudhary R, Singh K, Kumari S, Kumar R, Graham BB, Pasha MAQ, Rabyang S, Thinlas T, Mishra A
• Experimental Schistosoma haematobium pulmonary hypertension.
  Pulmonary circulation 2024 Kassa B, Fonseca-Balladares DC, Kumar R, Lee MH, Mickael C, Sanders L, Nolan K, Graham BB
• Hypobaric hypoxia drives selection of altitude-associated adaptative alleles in the Himalayan population.
  The Science of the total environment 2023 Sharma S, Koshy R, Kumar R, Mohammad G, Thinlas T, Graham BB, Pasha Q
• Dexamethasone prophylaxis protects from acute high-altitude illness by modifying the peripheral blood mononuclear cell inflammatory transcriptome.
  Bioscience reports 2023 Kumar R, Chanana N, Sharma K, Palmo T, Lee MH, Mishra A, Nolan K, Fonseca Balladares DC, Mickael C, Gupta MD, Thinlas T, Pasha Q, Graham BB
• Reversal of pulmonary veno-occlusive disease phenotypes by inhibition of the integrated stress response.
  bioRxiv : the preprint server for biology 2023 Prabhakar A, Kumar R, Wadhwa M, Ghatpande P, Zhang J, Zhao Z, Lizama CO, Kharbikar BN, Gräf S, Treacy CM, Morrell NW, Graham BB, Lagna G, Hata A
• Is pulmonary arterial hypertension associated with schistosomiasis distinct from pulmonary arterial hypertension associated with portal hypertension?
  JHLT open 2023 Graham BB, Hilton JF, Lee MH, Kumar R, Balladares DF, Rahaghi FN, Estépar RSJ, Mickael C, Lima RLB, Loureiro CMC, Lucena J, Oliveira RKF, Corrêa RA
• PFKFB3 Inhibits Fructose Metabolism in Pulmonary Microvascular Endothelial Cells.
  American journal of respiratory cell and molecular biology 2023 Lee JY, Stevens RP, Pastukh VV, Pastukh VM, Kozhukhar N, Alexeyev MF, Reisz JA, Nerguizian D, D'Alessandro A, Koloteva A, Gwin MS, Roberts JT, Borchert GM, Wagener BM, Pittet JF, Graham BB, Stenmark …
• Repetitive schistosoma exposure causes perivascular lung fibrosis and persistent pulmonary hypertension.
  Clinical science (London, England : 1979) 2023 Kumar R, Lee MH, Kassa B, Fonseca Balladares DC, Mickael C, Sanders L, Andruska A, Kumar M, Spiekerkoetter E, Bandeira A, Stenmark KR, Tuder RM, Graham BB
• Functional and molecular determinants of right ventricular response to severe pulmonary hypertension in a large animal model.
  American journal of physiology. Heart and circulatory physiology 2023 Brown RD, Hunter KS, Li M, Frid MG, Harral J, Krafsur GM, Holt TN, Williams J, Zhang H, Riddle SR, Edwards MG, Kumar S, Hu CJ, Graham BB, Walker LA, Garry FB, Buttrick PM, Lahm T, Kheyfets VO, Hansen …
• Potential long-term effects of SARS-CoV-2 infection on the pulmonary vasculature: Multilayered cross-talks in the setting of coinfections and comorbidities.
  PLoS pathogens 2023 Kumar R, Aktay-Cetin Ö, Craddock V, Morales-Cano D, Kosanovic D, Cogolludo A, Perez-Vizcaino F, Avdeev S, Kumar A, Ram AK, Agarwal S, Chakraborty A, Savai R, de Jesus Perez V, Graham BB, Butrous G, …
• The COVID-19 pandemic and pulmonary arterial hypertension in Italy: adaptation, outcomes and valuable lessons learned.
  The European respiratory journal 2022 Mickael C, Lee MH, Graham BB
• Exercise metabolomics in pulmonary arterial hypertension: Where pulmonary vascular metabolism meets exercise physiology.
  Frontiers in physiology 2022 Lee MH, Menezes TCF, Reisz JA, Ferreira EVM, Graham BB, Oliveira RKF
• HIV and Schistosoma Co-Exposure Leads to Exacerbated Pulmonary Endothelial Remodeling and Dysfunction Associated with Altered Cytokine Landscape.
  Cells 2022 Medrano-Garcia S, Morales-Cano D, Barreira B, Vera-Zambrano A, Kumar R, Kosanovic D, Schermuly RT, Graham BB, Perez-Vizcaino F, Mathie A, Savai R, Pullamseti S, Butrous G, Fernández-Malavé E, …
• The role of macrophages in right ventricular remodeling in experimental pulmonary hypertension.
  Pulmonary circulation 2022 Gu S, Mickael C, Kumar R, Lee MH, Sanders L, Kassa B, Harral J, Williams J, Hansen KC, Stenmark KR, Tuder RM, Graham BB
• Contribution of fatty acid oxidation to the pathogenesis of pulmonary hypertension.
  American journal of physiology. Lung cellular and molecular physiology 2022 Lee MH, Sanders L, Kumar R, Hernandez-Saavedra D, Yun X, Ford JA, Perez MJ, Mickael C, Gandjeva A, Koyanagi DE, Harral JW, Irwin DC, Kassa B, Eckel RH, Shimoda LA, Graham BB, Tuder RM
• Single-cell RNA sequencing and binary hierarchical clustering define lung interstitial macrophage heterogeneity in response to hypoxia.
  American journal of physiology. Lung cellular and molecular physiology 2022 Campbell NV, Mickael C, Kumar S, Zhang H, Campbell IL, Gillen AE, Trentin CO, Diener K, Gao B, Kheyfets VO, Gu S, Kumar R, Phang T, Brown RD, Graham BB, Stenmark KR
• Sexual Dimorphism of Dexamethasone as a Prophylactic Treatment in Pathologies Associated With Acute Hypobaric Hypoxia Exposure.
  Frontiers in pharmacology 2022 Chanana N, Palmo T, Sharma K, Kumar R, Shah B, Mahajan S, Palleda GM, Gupta MD, Kukreti R, Faruq M, Thinlas T, Graham BB, Pasha Q
• Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension.
  The Journal of clinical investigation 2022 Bertero T, Lu Y, Annis S, Hale A, Bhat B, Saggar R, Saggar R, Wallace WD, Ross DJ, Vargas SO, Graham BB, Kumar R, Black SM, Fratz S, Fineman JR, West JD, Haley KJ, Waxman AB, Chau BN, Cottrill KA, …
• Peripheral Blood Inflammation Profile of Patients with Pulmonary Arterial Hypertension Using the High-Throughput Olink Proteomics Platform.
  American journal of respiratory cell and molecular biology 2022 Mickael C, Kheyfets VO, Langouët-Astrié C, Lee MH, Sanders LA, Trentin CO, Sweatt AJ, Zamanian RT, Bull TM, Stenmark K, Graham BB, Tuder RM
• Rationale and design of a screening study to detect schistosomiasis-associated pulmonary hypertension in Ethiopia and Zambia.
  Pulmonary circulation 2022 Sinkala E, Ahmed HY, Sibomana JP, Lee MH, Kassa B, Kumar R, Mazimba S, Binegdie AB, Mpisa S, Wamundila K, Graham BB, Hilton JF
• Double Trouble: Airflow and Pulmonary Vascular Obstruction.
  American journal of respiratory and critical care medicine 2021 Lee MH, Graham BB, Bull TM
• Two Birds with One Stone: Helping the Pulmonary Arteries and the Right Ventricle by Targeting BMPR2 Signaling.
  American journal of respiratory cell and molecular biology 2021 Lee MH, Mickael C, Graham BB
• Endothelial cell PHD2-HIF1α-PFKFB3 contributes to right ventricle vascular adaptation in pulmonary hypertension.
  American journal of physiology. Lung cellular and molecular physiology 2021 Kassa B, Kumar R, Mickael C, Sanders L, Vohwinkel C, Lee MH, Gu S, Poth JM, Stenmark KR, Zhao YY, Tuder RM, Graham BB
• Arterial vascular volume changes with haemodynamics in schistosomiasis-associated pulmonary arterial hypertension.
  The European respiratory journal 2021 Rahaghi FN, Hilton JF, Corrêa RA, Loureiro C, Ota-Arakaki JS, Verrastro CGY, Lee MH, Mickael C, Nardelli P, Systrom DA, Waxman AB, Washko GR, San José Estépar R, Graham BB, Oliveira RKF
• Interleukin-6 mediates neutrophil mobilization from bone marrow in pulmonary hypertension.
  Cellular & molecular immunology 2021 Florentin J, Zhao J, Tai YY, Vasamsetti SB, O'Neil SP, Kumar R, Arunkumar A, Watson A, Sembrat J, Bullock GC, Sanders L, Kassa B, Rojas M, Graham BB, Chan SY, Dutta P
• Pathophysiology and potential future therapeutic targets using preclinical models of COVID-19.
  ERJ open research 2020 Kumar R, Lee MH, Mickael C, Kassa B, Pasha Q, Tuder R, Graham B
• Exploring New Therapeutic Pathways in Pulmonary Hypertension. Metabolism, Proliferation, and Personalized Medicine.
  American journal of respiratory cell and molecular biology 2020 George MP, Gladwin MT, Graham BB
• Sex-derived attributes contributing to SARS-CoV-2 mortality.
  American journal of physiology. Endocrinology and metabolism 2020 Chanana N, Palmo T, Sharma K, Kumar R, Graham BB, Pasha Q
• Stable isotope metabolomics of pulmonary artery smooth muscle and endothelial cells in pulmonary hypertension and with TGF-beta treatment.
  Scientific reports 2020 Hernandez-Saavedra D, Sanders L, Freeman S, Reisz JA, Lee MH, Mickael C, Kumar R, Kassa B, Gu S, D' Alessandro A, Stenmark KR, Tuder RM, Graham BB
• Suppression of HIF2 signalling attenuates the initiation of hypoxia-induced pulmonary hypertension.
  The European respiratory journal 2019 Hu CJ, Poth JM, Zhang H, Flockton A, Laux A, Kumar S, McKeon B, Mouradian G, Li M, Riddle S, Pugliese SC, Brown RD, Wallace EM, Graham BB, Frid MG, Stenmark KR
• A retrospective study of schistosomiasis-associated pulmonary hypertension from an endemic area in Brazil.
  International journal of cardiology. Heart & vasculature 2019 Botoni FA, Marinho CC, Carvalho VT, Mickael CS, Graham BB
• Systems Analysis of the Human Pulmonary Arterial Hypertension Lung Transcriptome.
  American journal of respiratory cell and molecular biology 2019 Stearman RS, Bui QM, Speyer G, Handen A, Cornelius AR, Graham BB, Kim S, Mickler EA, Tuder RM, Chan SY, Geraci MW
• BOLA (BolA Family Member 3) Deficiency Controls Endothelial Metabolism and Glycine Homeostasis in Pulmonary Hypertension.
  Circulation 2019 Yu Q, Tai YY, Tang Y, Zhao J, Negi V, Culley MK, Pilli J, Sun W, Brugger K, Mayr J, Saggar R, Saggar R, Wallace WD, Ross DJ, Waxman AB, Wendell SG, Mullett SJ, Sembrat J, Rojas M, Khan OF, Dahlman JE,…
• Comparing pulmonary hypertension severity between rat strains suggests right ventricle NK cells are protective.
  Cardiovascular research 2019 Mickael C, Lee MH, Gu S, Graham BB
• The Role of Type 2 Inflammation in Schistosoma-Induced Pulmonary Hypertension.
  Frontiers in immunology 2019 Mickael CS, Graham BB
• Finding the Target: In Silico and Genetic Screening for Mechanistically Novel Drugs in Pulmonary Arterial Hypertension.
  American journal of respiratory and critical care medicine 2019 Graham BB, Yu PB
• Common genetic variants in pulmonary arterial hypertension.
  The Lancet. Respiratory medicine 2018 Gu S, Kumar R, Lee MH, Mickael C, Graham BB
• Paclitaxel blocks Th2-mediated TGF-β activation in Schistosoma mansoni-induced pulmonary hypertension.
  Pulmonary circulation 2018 Kassa B, Mickael C, Kumar R, Sanders L, Koyanagi D, Hernandez-Saavedra D, Tuder RM, Graham BB
• Urocortin 2: will a drug targeting both the vasculature and the right ventricle be the future of pulmonary hypertension therapy?
  Cardiovascular research 2018 Stenmark KR, Graham BB
• NEDD9 targets COL3A1 to promote endothelial fibrosis and pulmonary arterial hypertension.
  Science translational medicine 2018 Samokhin AO, Stephens T, Wertheim BM, Wang RS, Vargas SO, Yung LM, Cao M, Brown M, Arons E, Dieffenbach PB, Fewell JG, Matar M, Bowman FP, Haley KJ, Alba GA, Marino SM, Kumar R, Rosas IO, Waxman AB, …
• Dominant Role for Regulatory T Cells in Protecting Females Against Pulmonary Hypertension.
  Circulation research 2018 Tamosiuniene R, Manouvakhova O, Mesange P, Saito T, Qian J, Sanyal M, Lin YC, Nguyen LP, Luria A, Tu AB, Sante JM, Rabinovitch M, Fitzgerald DJ, Graham BB, Habtezion A, Voelkel NF, Aurelian L, Nicolls…
• Dynamic and diverse changes in the functional properties of vascular smooth muscle cells in pulmonary hypertension.
  Cardiovascular research 2018 Stenmark KR, Frid MG, Graham BB, Tuder RM
• TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension.
  Nature communications 2017 Kumar R, Mickael C, Kassa B, Gebreab L, Robinson JC, Koyanagi DE, Sanders L, Barthel L, Meadows C, Fox D, Irwin D, Li M, McKeon BA, Riddle S, Dale Brown R, Morgan LE, Evans CM, Hernandez-Saavedra D, …
• A Time- and Compartment-Specific Activation of Lung Macrophages in Hypoxic Pulmonary Hypertension.
  Journal of immunology (Baltimore, Md. : 1950) 2017 Pugliese SC, Kumar S, Janssen WJ, Graham BB, Frid MG, Riddle SR, El Kasmi KC, Stenmark KR
• Enhanced inflammatory cell profiles in schistosomiasis-induced pulmonary vascular remodeling.
  Pulmonary circulation 2017 Ali Z, Kosanovic D, Kolosionek E, Schermuly RT, Graham BB, Mathie A, Butrous G
• Fatty Acid Metabolism, Bone Morphogenetic Protein Receptor Type 2, and the Right Ventricle.
  American journal of respiratory and critical care medicine 2016 Graham BB, Robinson JC, Tuder RM
• Increased mitochondrial arginine metabolism supports bioenergetics in asthma.
  The Journal of clinical investigation 2016 Xu W, Ghosh S, Comhair SA, Asosingh K, Janocha AJ, Mavrakis DA, Bennett CD, Gruca LL, Graham BB, Queisser KA, Kao CC, Wedes SH, Petrich JM, Tuder RM, Kalhan SC, Erzurum SC
• Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit.
  Cell reports 2015 Bertero T, Cottrill KA, Lu Y, Haeger CM, Dieffenbach P, Annis S, Hale A, Bhat B, Kaimal V, Zhang YY, Graham BB, Kumar R, Saggar R, Saggar R, Wallace WD, Ross DJ, Black SM, Fratz S, Fineman JR, Vargas …
• Severe pulmonary hypertension is associated with altered right ventricle metabolic substrate uptake.
  American journal of physiology. Lung cellular and molecular physiology 2015 Graham BB, Kumar R, Mickael C, Sanders L, Gebreab L, Huber KM, Perez M, Smith-Jones P, Serkova NJ, Tuder RM
• Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron-sulfur deficiency and pulmonary hypertension.
  EMBO molecular medicine 2015 White K, Lu Y, Annis S, Hale AE, Chau BN, Dahlman JE, Hemann C, Opotowsky AR, Vargas SO, Rosas I, Perrella MA, Osorio JC, Haley KJ, Graham BB, Kumar R, Saggar R, Saggar R, Wallace WD, Ross DJ, Khan OF…
• The crossroads of iron with hypoxia and cellular metabolism. Implications in the pathobiology of pulmonary hypertension.
  American journal of respiratory cell and molecular biology 2014 Robinson JC, Graham BB, Rouault TC, Tuder RM
• Schistosomiasis and the pulmonary vasculature (2013 Grover Conference series).
  Pulmonary circulation 2014 Graham BB, Kumar R
• Rtp801 suppression of epithelial mTORC1 augments endotoxin-induced lung inflammation.
  The American journal of pathology 2014 Nadon AM, Perez MJ, Hernandez-Saavedra D, Smith LP, Yang Y, Sanders LA, Gandjeva A, Chabon J, Koyanagi DE, Graham BB, Tuder RM, Schmidt EP
• Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension.
  The Journal of clinical investigation 2014 Bertero T, Lu Y, Annis S, Hale A, Bhat B, Saggar R, Saggar R, Wallace WD, Ross DJ, Vargas SO, Graham BB, Kumar R, Black SM, Fratz S, Fineman JR, West JD, Haley KJ, Waxman AB, Chau BN, Cottrill KA, …
• Adventitial fibroblasts induce a distinct proinflammatory/profibrotic macrophage phenotype in pulmonary hypertension.
  Journal of immunology (Baltimore, Md. : 1950) 2014 El Kasmi KC, Pugliese SC, Riddle SR, Poth JM, Anderson AL, Frid MG, Li M, Pullamsetti SS, Savai R, Nagel MA, Fini MA, Graham BB, Tuder RM, Friedman JE, Eltzschig HK, Sokol RJ, Stenmark KR
• Role of vascular endothelial growth factor signaling in Schistosoma-induced experimental pulmonary hypertension.
  Pulmonary circulation 2014 Chabon JJ, Gebreab L, Kumar R, Debella E, Tanaka T, Koyanagi D, Rodriguez Garcia A, Sanders L, Perez M, Tuder RM, Graham BB
• Functional prostacyclin synthase promoter polymorphisms. Impact in pulmonary arterial hypertension.
  American journal of respiratory and critical care medicine 2014 Stearman RS, Cornelius AR, Lu X, Conklin DS, Del Rosario MJ, Lowe AM, Elos MT, Fettig LM, Wong RE, Hara N, Cogan JD, Phillips JA, Taylor MR, Graham BB, Tuder RM, Loyd JE, Geraci MW
• Fat and cardiotoxicity in hereditary pulmonary hypertension.
  American journal of respiratory and critical care medicine 2014 Tuder RM, Robinson JC, Graham BB
• Protective role of IL-6 in vascular remodeling in Schistosoma pulmonary hypertension.
  American journal of respiratory cell and molecular biology 2013 Graham BB, Chabon J, Kumar R, Kolosionek E, Gebreab L, Debella E, Edwards M, Diener K, Shade T, Bifeng G, Bandeira A, Butrous G, Jones K, Geraci M, Tuder RM
• Updated approach for the assessment of ventilator-associated pneumonia.
  Critical care medicine 2013 Macht M, Robinson JC, Graham BB
• Pathology of pulmonary hypertension.
  Clinics in chest medicine 2013 Tuder RM, Stacher E, Robinson J, Kumar R, Graham BB
• Pulmonary veins in the normal lung and pulmonary hypertension due to left heart disease.
  American journal of physiology. Lung cellular and molecular physiology 2013 Hunt JM, Bethea B, Liu X, Gandjeva A, Mammen PP, Stacher E, Gandjeva MR, Parish E, Perez M, Smith L, Graham BB, Kuebler WM, Tuder RM
• Transforming growth factor-β signaling promotes pulmonary hypertension caused by Schistosoma mansoni.
  Circulation 2013 Graham BB, Chabon J, Gebreab L, Poole J, Debella E, Davis L, Tanaka T, Sanders L, Dropcho N, Bandeira A, Vandivier RW, Champion HC, Butrous G, Wang XJ, Wynn TA, Tuder RM
• A sinus venosus atrial septal defect is diagnosed by echocardiography with an unusual bubble study.
  Echocardiography (Mount Kisco, N.Y.) 2013 Dorosz JL, Fonseca BM, Kay JD, Graham BB, Salcedo EE, Quaife RA
• Schistosomiasis causes remodeling of pulmonary vessels in the lung in a heterogeneous localized manner: Detailed study.
  Pulmonary circulation 2013 Kolosionek E, King J, Rollinson D, Schermuly RT, Grimminger F, Graham BB, Morrell N, Butrous G
• Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2α.
  Cell metabolism 2013 Ghosh MC, Zhang DL, Jeong SY, Kovtunovych G, Ollivierre-Wilson H, Noguchi A, Tu T, Senecal T, Robinson G, Crooks DR, Tong WH, Ramaswamy K, Singh A, Graham BB, Tuder RM, Yu ZX, Eckhaus M, Lee J, …
• Fasting 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography to detect metabolic changes in pulmonary arterial hypertension hearts over 1 year.
  Annals of the American Thoracic Society 2013 Lundgrin EL, Park MM, Sharp J, Tang WH, Thomas JD, Asosingh K, Comhair SA, DiFilippo FP, Neumann DR, Davis L, Graham BB, Tuder RM, Dostanic I, Erzurum SC
• Modern age pathology of pulmonary arterial hypertension.
  American journal of respiratory and critical care medicine 2012 Stacher E, Graham BB, Hunt JM, Gandjeva A, Groshong SD, McLaughlin VV, Jessup M, Grizzle WE, Aldred MA, Cool CD, Tuder RM
• Targeting energetic metabolism: a new frontier in the pathogenesis and treatment of pulmonary hypertension.
  American journal of respiratory and critical care medicine 2011 Tuder RM, Davis LA, Graham BB
• Significant intrapulmonary Schistosoma egg antigens are not present in schistosomiasis-associated pulmonary hypertension.
  Pulmonary circulation 2011 Graham BB, Chabon J, Bandeira A, Espinheira L, Butrous G, Tuder RM
• Schistosomiasis-induced experimental pulmonary hypertension: role of interleukin-13 signaling.
  The American journal of pathology 2010 Graham BB, Mentink-Kane MM, El-Haddad H, Purnell S, Zhang L, Zaiman A, Redente EF, Riches DW, Hassoun PM, Bandeira A, Champion HC, Butrous G, Wynn TA, Tuder RM
• Tracheal Basal cells: a facultative progenitor cell pool.
  The American journal of pathology 2010 Cole BB, Smith RW, Jenkins KM, Graham BB, Reynolds PR, Reynolds SD
• Schistosomiasis-associated pulmonary hypertension: pulmonary vascular disease: the global perspective.
  Chest 2010 Graham BB, Bandeira AP, Morrell NW, Butrous G, Tuder RM
• Diabetes mellitus does not adversely affect outcomes from a critical illness.
  Critical care medicine 2010 Graham BB, Keniston A, Gajic O, Trillo Alvarez CA, Medvedev S, Douglas IS
• [Pathogenesis of pulmonary hypertension].
  Zhonghua yi xue za zhi 2009 Graham BB, Tuder RM
• TNFalpha inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation.
  American journal of physiology. Lung cellular and molecular physiology 2009 Borges VM, Vandivier RW, McPhillips KA, Kench JA, Morimoto K, Groshong SD, Richens TR, Graham BB, Muldrow AM, Van Heule L, Henson PM, Janssen WJ
• Clinical problem-solving. Kiss of death.
  The New England journal of medicine 2009 Graham BB, Kaul DR, Saint S, Janssen WJ
• Dyspnea, chest pain, and altered mental status in a 33-year-old carpenter.
  Chest 2008 Graham BB, Burnham EL, Janssen JS, Janssen WJ
• Cigarette smoke triggers code red: p21CIP1/WAF1/SDI1 switches on danger responses in the lung.
  American journal of respiratory cell and molecular biology 2008 Tuder RM, Yun JH, Graham BB
• Primary pulmonary lymphoma.
  The Annals of thoracic surgery 2005 Graham BB, Mathisen DJ, Mark EJ, Takvorian RW
• End-to-side venous anastomosis with the internal jugular vein stump: a preliminary report.
  Head & neck 2004 Graham BB, Varvares MA
• Pediatric tracheal surgery.
  The Annals of thoracic surgery 2002 Wright CD, Graham BB, Grillo HC, Wain JC, Mathisen DJ