Bria Macklin, PhD
Postdoctoral Scholar
Business Service Ctr
Chancellor/EVC/FAS

Publications (6)

Top publication keywords:
CRISPR-Cas SystemsMyocytes, CardiacNeuronsDNA RepairHumansGene EditingDNA DamageMutationInduced Pluripotent Stem CellsCell LineT-LymphocytesCell Differentiation

• EXCAVATE-HT: A Bioinformatic Pipeline to Identify Targetable Genomic Variants for Allele-Specific Editing.
  bioRxiv : the preprint server for biology 2026 Saxena AG, Ramey GD, Capra JA, Conklin BR, Macklin BL
• Leveraging human genetic variation to therapeutically target hundreds of genes with dominant & dispensable disease alleles.
  medRxiv : the preprint server for health sciences 2026 Ramey GD, Cowan QT, Saxena AG, Macklin BL, Watry HL, Mei X, Dierks P, Judge LM, Conklin BR, Capra JA
• Using image classifiers to predict CMT2A disease-relevant mitochondrial motility phenotypes in iPSC motor neurons.
  bioRxiv : the preprint server for biology 2026 Epstein L, Weiner AC, Macklin BL, Kelly KR, Conklin BR, Engelhardt BE
• Generation of WTD, a control human iPSC line for genetic research.
  Stem cell research 2025 Macklin BL, Runyon WV, Feliciano CM, Dierks PH, Kelly KR, Watry HL, Judge LM, Conklin BR
• Characterizing and controlling CRISPR repair outcomes in nondividing human cells.
  Nature communications 2025 Ramadoss GN, Namaganda SJ, Kumar MM, Hamilton JR, Sharma R, Chow KG, Workley LA, Macklin BL, Sun M, Ha AS, Liu JC, Fellmann C, Watry HL, Dierks PH, Bose RS, Jin J, Perez BS, Sandoval Espinoza CR, …
• Neuronal DNA repair reveals strategies to influence CRISPR editing outcomes.
  bioRxiv : the preprint server for biology 2025 Ramadoss GN, Namaganda SJ, Hamilton JR, Sharma R, Chow KG, Macklin BL, Sun M, Liu JC, Fellmann C, Watry HL, Jin J, Perez BS, Espinoza CRS, Matia MP, Lu SH, Judge LM, Nussenzweig A, Adamson B, Murthy N…