Bogdan Popescu, MD, PhD
Postdoctoral Scholar
Medicine
School of Medicine

Publications (77)

Top publication keywords:
EchocardiographyNatalizumabCardiomyopathy, HypertrophicEchocardiography, DopplerAtrial Function, LeftAccreditationParkinson DiseaseCardiologyCardiac Imaging TechniquesBlepharospasmAortic Valve StenosisStroke VolumeVentricular Function, LeftVentricular Dysfunction, LeftVentricular Remodeling

• DNA Sequencing of CD138 Cell Population Reveals TP53 and RAS-MAPK Mutations in Multiple Myeloma at Diagnosis.
  Cancers 2024 Dragomir M, Calugaru OT, Popescu B, Jardan C, Jardan D, Popescu M, Aposteanu S, Badeli?a S, Nedelcu G, ?erban C, Popa C, Vassu-Dimov T, Coriu D
• Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML.
  Cell reports. Medicine 2023 Popescu B, Stahlhut C, Tarver TC, Wishner S, Lee BJ, Peretz CAC, Luck C, Phojanakong P, Camara Serrano JA, Hongo H, Rivera JM, Xirenayi S, Chukinas JA, Steri V, Tasian SK, Stieglitz E, Smith CC
• RAS MULTI(ON) Inhibitor RMC-7977 Targets Oncogenic RAS Mutations and Overcomes RAS/MAPK-Mediated Resistance to FLT3 Inhibitors in AML Models
  RAS MULTI(ON) Inhibitor RMC-7977 Targets Oncogenic RAS Mutations and Overcomes RAS/MAPK-Mediated Resistance to FLT3 Inhibitors in AML Models 2023 Bogdan Popescu, Elliot Stieglitz, Catherine C. Smith
• Threshold Attenuation of Perk Signaling Is Sufficient to Overcome RAS-Mediated FLT3 Inhibitor Resistance
  Threshold Attenuation of Perk Signaling Is Sufficient to Overcome RAS-Mediated FLT3 Inhibitor Resistance 2023 Cheryl A C Peretz, Elaine Tran, Bogdan Popescu, Vanessa E. Kennedy, Tanya Kumar, Lisa McGary, Natalie Tantisira, Eric Wong, Jose M. Rivera, Simayijiang Xirenayi, Elliot Stieglitz, Catherine C. Smith, …
• Venetoclax and dinaciclib elicit synergistic preclinical efficacy against hypodiploid acute lymphoblastic leukemia.
  Haematologica 2023 Pariury H, Fandel J, Bachl S, Ang KK, Markossian S, Wilson CG, Braun BS, Popescu B, Wohlfeil M, Beckman K, Xirenayi S, Roy RP, Olshen AB, Smith C, Arkin MR, Loh ML, Diaz-Flores E

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• Sidestepping SHP2 inhibition.
  The Journal of experimental medicine 2023 Popescu B, Shannon K
• Blood
  Allosteric SHP2 Inhibitor RMC4550 Synergizes with Venetoclax in FLT3 and KIT Mutant Acute Myeloid Leukemia 2022 Bogdan Popescu, Carlos Stahlhut, Theodore C. Tarver, III, Timothy T. Ferng, Cheryl Peretz, Sydney Wishner, Paul Phojanakong, Veronica Steri, Eric B. Wong, Jose M. Rivera, Elliot Stieglitz, Catherine C…
• The "Cerebrospinal Fluid Sink Therapeutic Strategy" in Alzheimer's Disease-From Theory to Design of Applied Systems.
  Biomedicines 2022 Schreiner TG, Menéndez-González M, Popescu BO
• The Blood-Brain Barrier-A Key Player in Multiple Sclerosis Disease Mechanisms.
  Biomolecules 2022 Schreiner TG, Romanescu C, Popescu BO
• Predictive MRI Biomarkers in MS-A Critical Review.
  Medicina (Kaunas, Lithuania) 2022 Tiu VE, Enache I, Panea CA, Tiu C, Popescu BO
• Impact of Caffeine on Alzheimer's Disease Pathogenesis-Protective or Risk Factor?
  Life (Basel, Switzerland) 2022 Schreiner TG, Popescu BO
• Serum Uric Acid Levels in Parkinson's Disease: A Cross-Sectional Electronic Medical Record Database Study from a Tertiary Referral Centre in Romania.
  Medicina (Kaunas, Lithuania) 2022 Danau A, Dumitrescu L, Lefter A, Popescu BO
• Real-World Data Regarding Long-Term Administration of Natalizumab Derived from a Neurology Department along with Literature Review.
  CNS & neurological disorders drug targets 2022 Davidescu EI, Odajiu I, Sandu CD, Ghergu A, Luca D, Mure?anu DF, Popescu BO
• Amyloid Beta Dynamics in Biological Fluids-Therapeutic Impact.
  Journal of clinical medicine 2021 Schreiner TG, Popescu BO
• Characteristic Personality Traits of Multiple Sclerosis Patients-An Unicentric Prospective Observational Cohort Study.
  Journal of clinical medicine 2021 Davidescu EI, Odajiu I, Tulba D, Cucu C, Popescu BO
• Small Intestinal Bacterial Overgrowth as Potential Therapeutic Target in Parkinson's Disease.
  International journal of molecular sciences 2021 Danau A, Dumitrescu L, Lefter A, Tulba D, Popescu BO
• Psychological Traits and Behavioural Influences in Patients with Dystonia-An Observational Cohort Study in a Romanian Neurology Department.
  Life (Basel, Switzerland) 2021 Davidescu EI, Odajiu I, Tulba D, Mitrea I, Cucu C, Popescu BO
• Serum and Fecal Markers of Intestinal Inflammation and Intestinal Barrier Permeability Are Elevated in Parkinson's Disease.
  Frontiers in neuroscience 2021 Dumitrescu L, Marta D, Danau A, Lefter A, Tulba D, Cozma L, Manole E, Gherghiceanu M, Ceafalan LC, Popescu BO
• Progress and challenges in the treatment of cardiac amyloidosis: a review of the literature.
  ESC heart failure 2021 Adam RD, Coriu D, Jercan A, Badelita S, Popescu BA, Damy T, Jurcut R
• Of Criteria and Men-Diagnosing Atypical Parkinsonism: Towards an Algorithmic Approach.
  Brain sciences 2021 Cozma L, Avasilichioaei M, Dima N, Popescu BO
• An extremely uncommon case of pancreatic extragastrointestinal stromal tumor in a 53-year-old female patient.
  Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2021 Ene D, Florescu LM, Ene R, Popescu B, Gheonea IA
• Effects of Exogenous Androgens on Platelet Activity and Their Thrombogenic Potential in Supraphysiological Administration: A Literature Review.
  Journal of clinical medicine 2021 Rosca AE, Vladareanu AM, Mititelu A, Popescu BO, Badiu C, Caruntu C, Voiculescu SE, Onisâi M, Gologan S, Mirica R, Zagrean L
• Training, competence, and quality improvement in echocardiography: the European Association of Cardiovascular Imaging Recommendations: update 2020.
  European heart journal. Cardiovascular Imaging 2020 Popescu BA, Stefanidis A, Fox KF, Cosyns B, Delgado V, Di Salvo GD, Donal E, Flachskampf FA, Galderisi M, Lancellotti P, Muraru D, Sade LE, Edvardsen T, Reviewers: This document was reviewed by …
• CACNA1B gene variants in adult-onset isolated focal dystonia.
  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2020 Coco? R, Raicu F, Bajenaru OL, Olaru I, Dumitrescu L, Popescu BO
• Reversible left ventricular diastolic dysfunction-Overview and clinical implications.
  Echocardiography (Mount Kisco, N.Y.) 2020 Beladan CC, Botezatu S, Popescu BA
• Carotid arterial stiffness is increased and related to left ventricular function in patients with hypertrophic cardiomyopathy.
  European heart journal. Cardiovascular Imaging 2020 Rosca M, Mandes L, Ciuperca D, Calin A, Beladan CC, Enache R, Jurcut R, Coman IM, Ginghina C, Popescu BA
• Multimodality imaging in cardiac amyloidosis: a primer for cardiologists.
  European heart journal. Cardiovascular Imaging 2020 Jurcut R, Onciul S, Adam R, Stan C, Coriu D, Rapezzi C, Popescu BA
• The role of echocardiography for diagnosis and prognostic stratification in hypertrophic cardiomyopathy.
  Journal of echocardiography 2020 Mandes L, Rosca M, Ciuperca D, Popescu BA
• Role of advanced left ventricular imaging in adults with aortic stenosis.
  Heart (British Cardiac Society) 2020 Calin A, Mateescu AD, Popescu AC, Bing R, Dweck MR, Popescu BA
• Highly multiplexed proteomic assessment of human bone marrow in acute myeloid leukemia.
  Blood advances 2020 Çelik H, Lindblad KE, Popescu B, Gui G, Goswami M, Valdez J, DeStefano C, Lai C, Thompson J, Ghannam JY, Fantoni G, Biancotto A, Candia J, Cheung F, Sukumar G, Dalgard CL, Smith RH, Larochelle A, …
• Timed sequential salvage chemotherapy for relapsed or refractory acute myeloid leukemia.
  Clinical hematology international 2019 Popescu B, Sheela S, Thompson J, Grasmeder S, Intrater T, DeStefano CB, Hourigan CS, Lai C
• A Novel Proteomic Profiling of the Bone Marrow Microenvironment Reveals Elevated Levels of the Chemokine CCL23 Isoforms in Acute Myeloid Leukemia
  A Novel Proteomic Profiling of the Bone Marrow Microenvironment Reveals Elevated Levels of the Chemokine CCL23 Isoforms in Acute Myeloid Leukemia 2019 Haydar Celik, Katherine E. Lindblad, Bogdan Popescu, Giovanna Fantoni, Gege Gui, Janet Valdez, Meghali Goswami, Christin Destefano, Catherine E. Lai, Angélique Biancotto, Julián Candia, Foo Cheung, …
• Cancer Research
  Highly multiplexed proteomic assessment of the human acute myeloid leukemia bone marrow microenvironment 2019 Bogdan Popescu; Katherine Lindblad; Giovanna Fantoni; Gege Gui; Janet Valdez; Meghali Goswami; Christin DeStefano; Catherine Lai; Angélique Biancotto; Julián Candia; Foo Cheung; Julie Thompson; Laura …
• Left Atrial Dysfunction as an Independent Correlate of Heart Failure Symptoms in Patients With Severe Aortic Stenosis and Preserved Left Ventricular Ejection Fraction.
  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2019 Mateescu AD, Calin A, Beladan CC, Rosca M, Enache R, Baicus C, Botezatu S, Ginghina C, Popescu BA
• Oxidative Stress and the Microbiota-Gut-Brain Axis.
  Oxidative medicine and cellular longevity 2018 Dumitrescu L, Popescu-Olaru I, Cozma L, Tulba D, Hinescu ME, Ceafalan LC, Gherghiceanu M, Popescu BO
• Diastolic Function Assessment Revisited: Is Big Data Analysis Going to be a Big Hit?
  JACC. Cardiovascular imaging 2018 Popescu BA, Beladan CC, Popescu AC
• The year 2017 in the European Heart Journal-Cardiovascular Imaging: Part I.
  European heart journal. Cardiovascular Imaging 2018 Popescu BA, Petersen SE, Maurovich-Horvat P, Haugaa KH, Donal E, Maurer G, Edvardsen T
• Heterocellular molecular contacts in the mammalian stem cell niche.
  European journal of cell biology 2018 Ceafalan LC, Enciu AM, Fertig TE, Popescu BO, Gherghiceanu M, Hinescu ME, Radu E
• The EACVI.
  European heart journal 2018 Popescu BA
• NGS combined with phylogenetic analysis to detect HIV-1 dual infection in Romanian people who inject drugs.
  Microbes and infection 2018 Popescu B, Banica L, Nicolae I, Radu E, Niculescu I, Abagiu A, Otelea D, Paraschiv S
• Impaired Cardiac Function in Patients with Multiple Sclerosis by Comparison with Normal Subjects.
  Scientific reports 2018 Mincu RI, Magda SL, Mihaila S, Florescu M, Mihalcea DJ, Velcea A, Chiru A, Tiu C, Popescu BO, Cinteza M, Vinereanu D
• Right ventricular remodeling in athletes and in arrhythmogenic cardiomyopathy.
  Scandinavian cardiovascular journal : SCJ 2017 Chivulescu M, Haugaa K, Lie ØH, Edvardsen T, Ginghina C, Popescu BA, Jurcut R
• Update on radionuclide therapy in oncology.
  Oncology letters 2017 Nitipir C, Niculae D, Orlov C, Barbu MA, Popescu B, Popa AM, Pantea AMS, Stanciu AE, Galateanu B, Ginghina O, Papadakis GZ, Izotov BN, Spandidos DA, Tsatsakis AM, Negrei C
• Left atrial dysfunction as a determinant of pulmonary hypertension in patients with severe aortic stenosis and preserved left ventricular ejection fraction.
  The international journal of cardiovascular imaging 2017 Calin A, Mateescu AD, Rosca M, Beladan CC, Enache R, Botezatu S, Cosei I, Calin C, Simion M, Ginghina C, Popescu AC, Popescu BA
• Mechanical dyssynchrony in heart failure with preserved ejection fraction: a treatment target or a dead end?
  European journal of heart failure 2017 Popescu BA, Beladan CC, Popescu AC
• Sex Differences in Phenotypes of Bicuspid Aortic Valve and Aortopathy: Insights From a Large Multicenter, International Registry.
  Circulation. Cardiovascular imaging 2017 Kong WK, Regeer MV, Ng AC, McCormack L, Poh KK, Yeo TC, Shanks M, Parent S, Enache R, Popescu BA, Yip JW, Ma L, Kamperidis V, van der Velde ET, Mertens B, Ajmone Marsan N, Delgado V, Bax JJ
• Discovery of a new mutation in the desmin gene in a young patient with cardiomyopathy and muscular weakness.
  Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2017 JurcuT RO, Bastian AE, Militaru S, Popa A, Manole E, Popescu BA, Tallila J, Popescu BO, Ginghina CD
• A Congenital Gerbode Defect associated with a Rare Structural Abnormality of the Mitral Valve Diagnosed in an Adult Patient.
  Korean circulation journal 2016 Mateescu AD, Coman IM, Beladan CC, Radulescu B, Ginghina C, Popescu BA
• Cerebral arteriopathy with subcortical infarcts and leukoencephalopathy in acromegalic patient with severe headache.
  Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2016 Cima LN, Fica SV, Albu AI, Lambrescu IM, Lacau IS, Popescu BO, Gherghiceanu M, Badiu CV, Barbu CG
• Juxtacerebral Tissue Regeneration Potential: Telocytes Contribution.
  Advances in experimental medicine and biology 2016 Ceafalan LC, Popescu BO
• Shigeo Satomura: 60 years of Doppler ultrasound in medicine.
  Cardiovascular ultrasound 2015 Coman IM, Popescu BA
• Cardiovascular Dysfunction in Multiple Sclerosis.
  Maedica 2015 Mincu RI, Magda LS, Florescu M, Velcea A, Mihaila S, Mihalcea D, Popescu BO, Chiru A, Tiu C, Cinteza M, Vinereanu D
• Dynamic obstruction in hypertrophic cardiomyopathy.
  Current opinion in cardiology 2015 Popescu BA, Rosca M, Schwammenthal E
• Interstitial Outburst of Angiogenic Factors During Skeletal Muscle Regeneration After Acute Mechanical Trauma.
  Anatomical record (Hoboken, N.J. : 2007) 2015 Ceafalan LC, Manole E, Tanase CP, Codrici E, Mihai S, Gonzalez A, Popescu BO
• Right ventricular remodeling, its correlates, and its clinical impact in hypertrophic cardiomyopathy.
  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2015 Rosca M, Calin A, Beladan CC, Enache R, Mateescu AD, Gurzun MM, Varga P, Baicus C, Coman IM, Jurcut R, Ginghina C, Popescu BA
• Left ventricular shape and mass impact torsional dynamics in asymptomatic patients with chronic aortic regurgitation and normal left ventricular ejection fraction.
  The international journal of cardiovascular imaging 2015 Enache R, Popescu BA, Piazza R, Muraru D, Calin A, Beladan CC, Rosca M, Nicolosi GL, Ginghina C
• The left ventricle in aortic stenosis--imaging assessment and clinical implications.
  Cardiovascular ultrasound 2015 Calin A, Rosca M, Beladan CC, Enache R, Mateescu AD, Ginghina C, Popescu BA
• Management of organic mitral regurgitation: guideline recommendations and controversies.
  Korean circulation journal 2015 Gurzun MM, Popescu AC, Ginghina C, Popescu BA
• Updated standards and processes for accreditation of echocardiographic laboratories from The European Association of Cardiovascular Imaging: an executive summary.
  European heart journal. Cardiovascular Imaging 2014 Popescu BA, Stefanidis A, Nihoyannopoulos P, Fox KF, Ray S, Cardim N, Rigo F, Badano LP, Fraser AG, Pinto F, Zamorano JL, Habib G, Maurer G, Lancellotti P
• Impact of metabolic syndrome traits on cardiovascular function: should the Adult Treatment Panel III definition be further stratified?
  Journal of cardiovascular medicine (Hagerstown, Md.) 2014 Antonini-Canterin F, Mateescu AD, Vriz O, La Carrubba S, Di Bello V, Carerj S, Zito C, Sparacino L, Usurelu C, Ticulescu R, Ginghina C, Nicolosi GL, Popescu BA
• Cellular players in skeletal muscle regeneration.
  BioMed research international 2014 Ceafalan LC, Popescu BO, Hinescu ME
• Updated standards and processes for accreditation of echocardiographic laboratories from The European Association of Cardiovascular Imaging.
  European heart journal. Cardiovascular Imaging 2014 Popescu BA, Stefanidis A, Nihoyannopoulos P, Fox KF, Ray S, Cardim N, Rigo F, Badano LP, Fraser AG, Pinto F, Zamorano JL, Habib G, Maurer G, Lancellotti P, Andrade MJ, Donal E, Edvardsen T, Varga A
• Imaging of myocardial fibrosis in hypertrophic cardiomyopathy: what is the gold standard?
  Heart (British Cardiac Society) 2014 Popescu BA, Rosca M
• Correlation between global longitudinal strain and QRS voltage on electrocardiogram in patients with left ventricular hypertrophy.
  Echocardiography (Mount Kisco, N.Y.) 2013 Beladan CC, Popescu BA, Calin A, Rosca M, Matei F, Gurzun MM, Popara AV, Curea F, Ginghina C
• Is there a causal link between inflammation and dementia?
  BioMed research international 2013 Enciu AM, Popescu BO
• Left ventricular twist dynamics: principles and applications.
  Heart (British Cardiac Society) 2013 Beladan CC, Calin A, Rosca M, Ginghina C, Popescu BA
• Intracranial cysts: an imagery diagnostic challenge.
  TheScientificWorldJournal 2013 Oprisan A, Popescu BO
• Impact of associated significant aortic regurgitation on left ventricular remodeling and hemodynamic impairment in severe aortic valve stenosis.
  Cardiology 2013 Popescu AC, Antonini-Canterin F, Enache R, Nicolosi GL, Piazza R, Faggiano P, Cassin M, Dimulescu D, Ginghina C, Popescu BA
• A paravertebral pulsatile mass.
  Circulation 2012 Popescu BA, Savu O, Beladan CC, Rosça M, Lupescu I, Ginghina C
• Apoptosis in seborrheic keratoses: an open door to a new dermoscopic score.
  Journal of cellular and molecular medicine 2012 Simionescu O, Popescu BO, Costache M, Manole E, Spulber S, Gherghiceanu M, Blum A
• Platelet-derived growth factor receptor-β-positive telocytes in skeletal muscle interstitium.
  Journal of cellular and molecular medicine 2012 Suciu LC, Popescu BO, Kostin S, Popescu LM
• Duodopa infusion treatment: a point of view from the gastroenterologist.
  Journal of gastrointestinal and liver diseases : JGLD 2011 Negreanu L, Popescu BO, Babiuc RD, Ene A, Bajenaru OA, Smarandache GC
• Impact of aortic stiffness on left ventricular function and B-type natriuretic peptide release in severe aortic stenosis.
  European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology 2011 Rosca M, Magne J, Calin A, Popescu BA, Piérard LA, Lancellotti P
• Neurobiology of vascular dementia.
  Journal of aging research 2011 Enciu AM, Constantinescu SN, Popescu LM, Muresanu DF, Popescu BO
• Neuroregeneration in neurodegenerative disorders.
  BMC neurology 2011 Enciu AM, Nicolescu MI, Manole CG, Muresanu DF, Popescu LM, Popescu BO
• The Romanian Working Group on Echocardiography: past, present, and future.
  European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology 2011 Popescu BA
• Images in cardiology. Atrioventricular block in the elderly: does echocardiography hold the key?
  Journal of the American College of Cardiology 2011 Popescu BA, Muraru D, Beladan CC, Lacau IS, Ginghina C