Bogdan Popescu, MD, PhD
Specialist
Medicine
School of Medicine

Awards

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• Abstract Achievement Award, American Society of Hematology (ASH), 2024
• Summa Cum Laude, Carol Davila University of Medicine and Pharmacy, 2024
• Abstract Achievement Award, American Society of Hematology (ASH), 2023
• Abstract Achievement Award, American Society of Hematology (ASH), 2021
• Young Investigator Travel Grant, Society of Hematologic Oncology (SOHO), 2018

Education & Training

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• Ph.D. Biomedical Sciences Carol Davila University of Medicine and Pharmacy 01/2024
• M.D. Medicine Carol Davila University of Medicine and Pharmacy 09/2015

Publications (12)

Top publication keywords:
env Gene Products, Human Immunodeficiency VirusBone Marrowfms-Like Tyrosine Kinase 3RomaniaReassortant VirusesLeukemia, Myeloid, AcutePrecursor Cell Lymphoblastic Leukemia-LymphomaSuperinfectionMitogen-Activated Protein KinasesApoptosisDrug UsersHIV-1CRISPR-Cas SystemsGenome, ViralProto-Oncogene Proteins c-bcl-2

• Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML.
  Cell reports. Medicine 2023 Popescu B, Stahlhut C, Tarver TC, Wishner S, Lee BJ, Peretz CAC, Luck C, Phojanakong P, Camara Serrano JA, Hongo H, Rivera JM, Xirenayi S, Chukinas JA, Steri V, Tasian SK, Stieglitz E, Smith CC
• Sidestepping SHP2 inhibition.
  The Journal of experimental medicine 2023 Popescu B, Shannon K
• DNA Sequencing of CD138 Cell Population Reveals TP53 and RAS-MAPK Mutations in Multiple Myeloma at Diagnosis.
  Cancers 2024 Dragomir M, Calugaru OT, Popescu B, Jardan C, Jardan D, Popescu M, Aposteanu S, Badeli?a S, Nedelcu G, ?erban C, Popa C, Vassu-Dimov T, Coriu D
• RAS MULTI(ON) Inhibitor RMC-7977 Targets Oncogenic RAS Mutations and Overcomes RAS/MAPK-Mediated Resistance to FLT3 Inhibitors in AML Models
  RAS MULTI(ON) Inhibitor RMC-7977 Targets Oncogenic RAS Mutations and Overcomes RAS/MAPK-Mediated Resistance to FLT3 Inhibitors in AML Models 2023 Bogdan Popescu, Elliot Stieglitz, Catherine C. Smith
• Threshold Attenuation of Perk Signaling Is Sufficient to Overcome RAS-Mediated FLT3 Inhibitor Resistance
  Threshold Attenuation of Perk Signaling Is Sufficient to Overcome RAS-Mediated FLT3 Inhibitor Resistance 2023 Cheryl A C Peretz, Elaine Tran, Bogdan Popescu, Vanessa E. Kennedy, Tanya Kumar, Lisa McGary, Natalie Tantisira, Eric Wong, Jose M. Rivera, Simayijiang Xirenayi, Elliot Stieglitz, Catherine C. Smith, …

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• Venetoclax and dinaciclib elicit synergistic preclinical efficacy against hypodiploid acute lymphoblastic leukemia.
  Haematologica 2023 Pariury H, Fandel J, Bachl S, Ang KK, Markossian S, Wilson CG, Braun BS, Popescu B, Wohlfeil M, Beckman K, Xirenayi S, Roy RP, Olshen AB, Smith C, Arkin MR, Loh ML, Diaz-Flores E
• Blood
  Allosteric SHP2 Inhibitor RMC4550 Synergizes with Venetoclax in FLT3 and KIT Mutant Acute Myeloid Leukemia 2022 Bogdan Popescu, Carlos Stahlhut, Theodore C. Tarver, III, Timothy T. Ferng, Cheryl Peretz, Sydney Wishner, Paul Phojanakong, Veronica Steri, Eric B. Wong, Jose M. Rivera, Elliot Stieglitz, Catherine C…
• Highly multiplexed proteomic assessment of human bone marrow in acute myeloid leukemia.
  Blood advances 2020 Çelik H, Lindblad KE, Popescu B, Gui G, Goswami M, Valdez J, DeStefano C, Lai C, Thompson J, Ghannam JY, Fantoni G, Biancotto A, Candia J, Cheung F, Sukumar G, Dalgard CL, Smith RH, Larochelle A, …
• Timed sequential salvage chemotherapy for relapsed or refractory acute myeloid leukemia.
  Clinical hematology international 2019 Popescu B, Sheela S, Thompson J, Grasmeder S, Intrater T, DeStefano CB, Hourigan CS, Lai C
• A Novel Proteomic Profiling of the Bone Marrow Microenvironment Reveals Elevated Levels of the Chemokine CCL23 Isoforms in Acute Myeloid Leukemia
  A Novel Proteomic Profiling of the Bone Marrow Microenvironment Reveals Elevated Levels of the Chemokine CCL23 Isoforms in Acute Myeloid Leukemia 2019 Haydar Celik, Katherine E. Lindblad, Bogdan Popescu, Giovanna Fantoni, Gege Gui, Janet Valdez, Meghali Goswami, Christin Destefano, Catherine E. Lai, Angélique Biancotto, Julián Candia, Foo Cheung, …
• Cancer Research
  Highly multiplexed proteomic assessment of the human acute myeloid leukemia bone marrow microenvironment 2019 Bogdan Popescu; Katherine Lindblad; Giovanna Fantoni; Gege Gui; Janet Valdez; Meghali Goswami; Christin DeStefano; Catherine Lai; Angélique Biancotto; Julián Candia; Foo Cheung; Julie Thompson; Laura …
• NGS combined with phylogenetic analysis to detect HIV-1 dual infection in Romanian people who inject drugs.
  Microbes and infection 2018 Popescu B, Banica L, Nicolae I, Radu E, Niculescu I, Abagiu A, Otelea D, Paraschiv S