Biswarathan Ramani, MD, PhD
Clinical Fellow
Pathology
School of Medicine

Publications (19)

Top publication keywords:
Machado-Joseph DiseaseAtaxin-3ImmunohistochemistryCauda EquinaDNA MethylationHistiocytoma, Benign FibrousParaganglioma, Extra-AdrenalNuclear ProteinsCentral Nervous System NeoplasmsHistiocytosis, SinusSpinocerebellar AtaxiasAlternative SplicingDNA Copy Number VariationsGangliogliomaParaganglioma

• Scalable, cell type-selective, AAV-based in vivo CRISPR screening in the mouse brain.
  bioRxiv : the preprint server for biology 2023 Ramani B, Rose IVL, Pan A, Tian R, Ma K, Palop JJ, Kampmann M
• Cauda Equina Neuroendocrine Tumors: Distinct Epithelial Neuroendocrine Neoplasms of Spinal Origin.
  The American journal of surgical pathology 2022 Asa SL, Mete O, Schüller U, Ramani B, Mirchia K, Perry A
• Patterns of Extraneural Metastases in Children With Ependymoma.
  Journal of pediatric hematology/oncology 2022 Chan PP, Whipple NS, Ramani B, Solomon DA, Zhou H, Linscott LL, Kestle JRW, Bruggers CS
• Targeted Next-Generation Sequencing Reveals Divergent Clonal Evolution in Components of Composite Pleomorphic Xanthoastrocytoma-Ganglioglioma.
  Journal of neuropathology and experimental neurology 2022 Lucas CG, Davidson CJ, Alashari M, Putnam AR, Whipple NS, Bruggers CS, Mendez JS, Cheshier SH, Walker JB, Ramani B, Cadwell CR, Sullivan DV, Lu R, Mirchia K, Van Ziffle J, Devine P, Goldschmidt E, …
• Iris and Ciliary Body Melanocytomas Are Defined by Solitary GNAQ Mutation Without Additional Oncogenic Alterations.
  Ophthalmology 2022 Solomon DA, Ramani B, Eiger-Moscovich M, Milman T, Uludag G, Crawford JB, Phan I, Char DH, Shields CL, Eagle RC, Bastian BC, Bloomer MM, Pekmezci M

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• Orbital Rosai-Dorfman Disease Presenting as Optic Neuritis.
  Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 2021 Virk HS, Shahlaie K, Ramani B, Perry A, Fragoso R, Tuscano J, Liu YA
• Clinical Problem Solving: An Older Woman With Weakness from Head to Toe.
  The Neurohospitalist 2021 Hartmann DA, Bock M, Douglas V, Gerdts J, Ramani B, Shah M
• Intracranial mesenchymal tumor with FET-CREB fusion-A unifying diagnosis for the spectrum of intracranial myxoid mesenchymal tumors and angiomatoid fibrous histiocytoma-like neoplasms.
  Brain pathology (Zurich, Switzerland) 2021 Sloan EA, Chiang J, Villanueva-Meyer JE, Alexandrescu S, Eschbacher JM, Wang W, Mafra M, Ud Din N, Carr-Boyd E, Watson M, Punsoni M, Oviedo A, Gilani A, Kleinschmidt-DeMasters BK, Coss DJ, Lopes MB, …
• The immunohistochemical, DNA methylation, and chromosomal copy number profile of cauda equina paraganglioma is distinct from extra-spinal paraganglioma.
  Acta neuropathologica 2020 Ramani B, Gupta R, Wu J, Barreto J, Bollen AW, Tihan T, Mummaneni PV, Ames C, Clark A, Oberheim Bush NA, Butowski N, Phillips D, King BE, Bator SM, Treynor EC, Zherebitskiy V, Quinn PS, Walker JB, …
• Comprehensive analysis of diverse low-grade neuroepithelial tumors with FGFR1 alterations reveals a distinct molecular signature of rosette-forming glioneuronal tumor.
  Acta neuropathologica communications 2020 Lucas CG, Gupta R, Doo P, Lee JC, Cadwell CR, Ramani B, Hofmann JW, Sloan EA, Kleinschmidt-DeMasters BK, Lee HS, Wood MD, Grafe M, Born D, Vogel H, Salamat S, Puccetti D, Scharnhorst D, Samuel D, …
• Gliomas arising in the setting of Li-Fraumeni syndrome stratify into two molecular subgroups with divergent clinicopathologic features.
  Acta neuropathologica 2020 Sloan EA, Hilz S, Gupta R, Cadwell C, Ramani B, Hofmann J, Kline CN, Banerjee A, Reddy A, Oberheim Bush NA, Chang S, Braunstein S, Chang EF, Raffel C, Gupta N, Sun PP, Kim JYH, Moes G, Alva E, Li R, …
• The Right Frame.
  Journal of hospital medicine 2019 Minter DJ, Geha RM, Boslett BA, Chung SA, Ramani B, Manesh R
• Comparison of spinocerebellar ataxia type 3 mouse models identifies early gain-of-function, cell-autonomous transcriptional changes in oligodendrocytes.
  Human molecular genetics 2017 Ramani B, Panwar B, Moore LR, Wang B, Huang R, Guan Y, Paulson HL
• A knockin mouse model of spinocerebellar ataxia type 3 exhibits prominent aggregate pathology and aberrant splicing of the disease gene transcript.
  Human molecular genetics 2017 Ramani B, Harris GM, Huang R, Seki T, Murphy GG, Carmo Costa MD, Fischer S, Saunders TL, Xia G, McEachin RC, Paulson HL
• Differential recruitment of UBQLN2 to nuclear inclusions in the polyglutamine diseases HD and SCA3.
  Neurobiology of disease 2015 Zeng L, Wang B, Merillat SA, Minakawa EN, Perkins MD, Ramani B, Tallaksen-Greene SJ, Costa MDC, Albin RL, Paulson HL
• A knockin mouse model of spinocerebellar ataxia type 3 exhibits prominent aggregate pathology and aberrant splicing of the disease gene transcript.
  Human molecular genetics 2014 Ramani B, Harris GM, Huang R, Seki T, Murphy GG, Costa Mdo C, Fischer S, Saunders TL, Xia G, McEachin RC, Paulson HL
• Probing cellular protein complexes using single-molecule pull-down.
  Nature 2011 Jain A, Liu R, Ramani B, Arauz E, Ishitsuka Y, Ragunathan K, Park J, Chen J, Xiang YK, Ha T
• Agonist dose-dependent phosphorylation by protein kinase A and G protein-coupled receptor kinase regulates beta2 adrenoceptor coupling to G(i) proteins in cardiomyocytes.
  The Journal of biological chemistry 2009 Liu R, Ramani B, Soto D, De Arcangelis V, Xiang Y
• Norepinephrine- and epinephrine-induced distinct beta2-adrenoceptor signaling is dictated by GRK2 phosphorylation in cardiomyocytes.
  The Journal of biological chemistry 2007 Wang Y, De Arcangelis V, Gao X, Ramani B, Jung YS, Xiang Y