Binh Trinh, MD, PhD
Associate Professor
Surgery
School of Medicine

He is especially interested in minimally invasive surgical techniques, including video-assisted thoracoscopic surgery and robotics applications.

Trinh's research has explored the role of DNA methylation (a specific change to DNA that affects gene expression) in cancer, early cancer detection, and prognosis for lung and esophageal cancers.

Trinh earned dual degrees from a combined medical and doctoral program at the Keck School of Medicine of the University of Southern California (USC). He went on to complete his general surgery residency at USC, followed by a fellowship in cardiothoracic surgery at UCSF. He joined the staff at UCSF in 2016.

Trinh is an active member of the American College of Surgeons, Society of Thoracic Surgeons and American Medical Association.

• The association of post-operative delirium with patient-reported outcomes and mortality after lung transplantation.
  Clinical transplantation 2021 DeBolt CL, Gao Y, Sutter N, Soong A, Leard L, Jeffrey G, Kleinhenz ME, Calabrese D, Greenland J, Venado A, Hays SR, Shah R, Kukreja J, Trinh B, Kolaitis NA, Douglas V, Diamond JM, Smith P, Singer J
• Lung transplantation from swimming pool drowning victims: A case series.
  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2021 Tsou S, Chen J, Brzezinski M, Hays S, Leard L, Singer JP, Trinh B, Kukreja J
• Risk Factors and Outcomes of Extracorporeal Membrane Oxygenation as a Bridge to Lung Transplantation.
  Seminars in thoracic and cardiovascular surgery 2020 Kukreja J, Tsou S, Chen J, Trinh BN, Feng C, Golden JA, Hays S, Deuse T, Singer JP, Brzezinski M
• Reversal of TGFβ1-Driven Profibrotic State in Patients with Pulmonary Fibrosis.
  The New England journal of medicine 2020 Chapman HA, Wei Y, Montas G, Leong D, Golden JA, Trinh BN, Wolters PJ, Le Saux CJ, Jones KD, Hills NK, Foster E, Oldham JM, Linderholm AL, Kotak P, Decaris M, Turner S, Song JW
• MethyLight and Digital MethyLight.
  Methods in molecular biology (Clifton, N.J.) 2018 Campan M, Weisenberger DJ, Trinh B, Laird PW
• Alterations in deoxyribonucleic acid (DNA) methylation patterns of Calca, Timp3, Mmp2, and Igf2r are associated with chronic cystitis in a cyclophosphamide-induced mouse model.
  Urology 2013 Choi IS, Yu K, Kim J, De Guzman E, Weisenberger DJ, Oghamian S, Kim HJ, Lee KH, Carroll C, Trinh BN, Kim M, Houshdaran S, Laird PW, Jones PA, Warburton D, Liang G, Koh CJ
• MethyLight.
  Methods in molecular biology (Clifton, N.J.) 2009 Campan M, Weisenberger DJ, Trinh B, Laird PW
• DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight.
  Nucleic acids research 2008 Weisenberger DJ, Trinh BN, Campan M, Sharma S, Long TI, Ananthnarayan S, Liang G, Esteva FJ, Hortobagyi GN, McCormick F, Jones PA, Laird PW
• 2'-Deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]-5-azacytidine: a novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1.
  Cancer letters 2008 Byun HM, Choi SH, Laird PW, Trinh B, Siddiqui MA, Marquez VE, Yang AS
• Dnmt1 deficiency leads to enhanced microsatellite instability in mouse embryonic stem cells.
  Nucleic acids research 2004 Kim M, Trinh BN, Long TI, Oghamian S, Laird PW
• Thymidylate synthase: a novel genetic determinant of plasma homocysteine and folate levels.
  Human genetics 2002 Trinh BN, Ong CN, Coetzee GA, Yu MC, Laird PW
• DNA methyltransferase deficiency modifies cancer susceptibility in mice lacking DNA mismatch repair.
  Molecular and cellular biology 2002 Trinh BN, Long TI, Nickel AE, Shibata D, Laird PW