Biao Wang, PhD
Associate Professor
Cardiovascular Research Inst
School of Medicine

Education & Training

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• Postdoctoral Studies Graduate Division University of California, San Francisco

Grants and Projects

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• Regulation of beige adipocyte plasticity in inguinal white adipose tissue, NIH/NIDDK, 2023-2027
• Ucp1-independent functions in brown and beige adipocytes, NIH, 2021-2025
• TSSK-dependent signaling pathway in spermatogenesis, NIH, 2022-2023
• Molecular control of cardiac regenerative potential, NIH, 2017-2022
• Transcriptional control in brown and beige adipocytes, NIH, 2015-2021
• Innate Immune Mechanisms of Thermogenesis, NIH, 2011-2020

Publications (13)

Top publication keywords:
Histone DeacetylasesAdipose Tissue, BrownThermogenesisInsulinActivating Transcription Factor 4Adipose Tissue, WhiteCell PlasticityMitochondrial MembranesCold TemperatureAdipocytes, BrownUncoupling Protein 1Sympathetic Nervous SystemAdiposityEnergy MetabolismAdipocytes, Beige

• Brown adipocyte ATF4 activation improves thermoregulation and systemic metabolism.
  Cell reports 2021 Paulo E, Zhang Y, Masand R, Huynh TL, Seo Y, Swaney DL, Soucheray M, Stevenson E, Jimenez-Morales D, Krogan NJ, Wang B
• Autoregulation of insulin receptor signaling through MFGE8 and the αvβ5 integrin.
  Proceedings of the National Academy of Sciences of the United States of America 2021 Datta R, Lizama CO, Soltani AK, Mckleroy W, Podolsky MJ, Yang CD, Huynh TL, Cautivo KM, Wang B, Koliwad SK, Abumrad NA, Atabai K
• Role of mTORC2 in biphasic regulation of brown fat metabolism in response to mild and severe cold.
  The Journal of biological chemistry 2021 Allu PKR, Paulo E, Bertholet AM, Situ G, Lee SH, Wu Y, Gleason CE, Saha B, Chawla A, Wang B, Pearce D
• A thermogenic fat-epithelium cell axis regulates intestinal disease tolerance.
  Proceedings of the National Academy of Sciences of the United States of America 2020 Man K, Bowman C, Braverman KN, Escalante V, Tian Y, Bisanz JE, Ganeshan K, Wang B, Patterson A, Bayrer JR, Turnbaugh PJ, Chawla A
• Salt-inducible kinase 1 maintains HDAC7 stability to promote pathologic cardiac remodeling.
  The Journal of clinical investigation 2020 Hsu A, Duan Q, McMahon S, Huang Y, Wood SA, Gray NS, Wang B, Bruneau BG, Haldar SM

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• Towards a Better Understanding of Beige Adipocyte Plasticity.
  Cells 2019 Paulo E, Wang B
• Adipocyte HDAC4 activation leads to beige adipocyte expansion and reduced adiposity.
  The Journal of endocrinology 2018 Paulo E, Wu D, Hecker P, Zhang Y, Wang B
• Sympathetic inputs regulate adaptive thermogenesis in brown adipose tissue through cAMP-Salt inducible kinase axis.
  Scientific reports 2018 Paulo E, Wu D, Wang Y, Zhang Y, Wu Y, Swaney DL, Soucheray M, Jimenez-Morales D, Chawla A, Krogan NJ, Wang B
• Proteome Imbalance of Mitochondrial Electron Transport Chain in Brown Adipocytes Leads to Metabolic Benefits.
  Cell metabolism 2018 Masand R, Paulo E, Wu D, Wang Y, Swaney DL, Jimenez-Morales D, Krogan NJ, Wang B
• Adipocyte Liver Kinase b1 Suppresses Beige Adipocyte Renaissance Through Class IIa Histone Deacetylase 4.
  Diabetes 2017 Wang Y, Paulo E, Wu D, Wu Y, Huang W, Chawla A, Wang B
• A hormone-dependent module regulating energy balance.
  Cell 2011 Wang B, Moya N, Niessen S, Hoover H, Mihaylova MM, Shaw RJ, Yates JR, Fischer WH, Thomas JB, Montminy M
• The insulin-regulated CREB coactivator TORC promotes stress resistance in Drosophila.
  Cell metabolism 2008 Wang B, Goode J, Best J, Meltzer J, Schilman PE, Chen J, Garza D, Thomas JB, Montminy M
• Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity.
  Cancer cell 2003 Wang B, Xiao Y, Ding BB, Zhang N, Yuan Xb, Gui L, Qian KX, Duan S, Chen Z, Rao Y, Geng JG