Beika Zhu, PhD
Postdoctoral Scholar
Pediatrics
School of Medicine

Publications (4)

Top publication keywords:
HEK293 CellsStructure-Activity RelationshipReceptors, G-Protein-CoupledLigandsSynapsesMicrogliaAutism Spectrum DisorderSmall Molecule LibrariesMice, KnockoutAutistic DisorderCells, CulturedPhosphatidylserinesLimoninsDose-Response Relationship, DrugMembrane Proteins

• GPR56 S4 variant is required for microglia-mediated synaptic pruning.
  Glia 2022 Li T, Luo R, Schmidt R, D'Alessandro N, Kishore P, Zhu B, Yu D, Piao X
• Microglial GPR56 is the molecular target of maternal immune activation-induced parvalbumin-positive interneuron deficits.
  Science advances 2022 Yu D, Li T, Delpech JC, Zhu B, Kishore P, Koshi T, Luo R, Pratt KJB, Popova G, Nowakowski TJ, Villeda SA, Piao X
• Phospholipid-flippase chaperone CDC50A is required for synapse maintenance by regulating phosphatidylserine exposure.
  The EMBO journal 2021 Li T, Yu D, Oak HC, Zhu B, Wang L, Jiang X, Molday RS, Kriegstein A, Piao X
• GAIN domain-mediated cleavage is required for activation of G protein-coupled receptor 56 (GPR56) by its natural ligands and a small-molecule agonist.
  The Journal of biological chemistry 2019 Zhu B, Luo R, Jin P, Li T, Oak HC, Giera S, Monk KR, Lak P, Shoichet BK, Piao X