Balyn Zaro, PhD
Assistant Professor
Pharmaceutical Chemistry
School of Pharmacy
Education & Training
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- Stem Cell Biology and Innate Immunity Stanford School of Medicine 08/2019
- Chemical Biology Scripps Research Institute 08/2017
- Ph.D. Chemical Biology University of Southern California 08/2014
- B.S. Chemistry University of Southern California 06/2009
Websites
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- @@balynzaro on Twitter (twitter.com)
- Zaro Lab Website (pharm.ucsf.edu)
Publications (33)
Top publication keywords:
Carbohydrate MetabolismDeoxyglucoseDimethyl FumarateAcetylglucosaminePlasma CellsProteomicsMyeloid Differentiation Factor 88Molecular ProbesInterleukin-1 Receptor-Associated KinasesGlucosamineN-AcetylglucosaminyltransferasesProtein Kinase InhibitorsFumaratesGlycosylationAlkynes
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Correction to "Changes in Metabolic Chemical Reporter Structure Yield a Selective Probe of O-GlcNAc Modification".
Journal of the American Chemical Society 2023 Chuh KN, Zaro BW, Piller F, Piller V, Pratt MR -
Longitudinal map of transcriptome changes in the Lyme pathogen Borrelia burgdorferi during tick-borne transmission.
eLife 2023 Sapiro AL, Hayes BM, Volk RF, Zhang JY, Brooks DM, Martyn C, Radkov A, Zhao Z, Kinnersley M, Secor PR, Zaro BW, Chou S -
EMC chaperone-CaV structure reveals an ion channel assembly intermediate.
Nature 2023 Chen Z, Mondal A, Abderemane-Ali F, Jang S, Niranjan S, Montaño JL, Zaro BW, Minor DL -
MFGE8 links absorption of dietary fatty acids with catabolism of enterocyte lipid stores through HNF4γ-dependent transcription of CES enzymes.
Cell reports 2023 Datta R, Gholampour MA, Yang CD, Volk R, Lin S, Podolsky MJ, Arnold T, Rieder F, Zaro BW, Verzi M, Lehner R, Abumrad N, Lizama CO, Atabai K -
Wnt5a-Vangl1/2 signaling regulates the position and direction of lung branching through the cytoskeleton and focal adhesions.
PLoS biology 2022 Zhang K, Yao E, Chuang E, Chen B, Chuang EY, Volk RF, Hofmann KL, Zaro B, Chuang PT
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Secreted fungal virulence effector triggers allergic inflammation via TLR4.
Nature 2022 Dang EV, Lei S, Radkov A, Volk RF, Zaro BW, Madhani HD -
Improved Electrophile Design for Exquisite Covalent Molecule Selectivity.
ACS chemical biology 2022 Montaño JL, Wang BJ, Volk RF, Warrington SE, Garda VG, Hofmann KL, Chen LC, Zaro BW -
Proteomic characterization of phagocytic primary human monocyte-derived macrophages.
RSC chemical biology 2022 Volk RF, Montaño JL, Warrington SE, Hofmann KL, Zaro BW -
Refinement of Covalent EGFR Inhibitor AZD9291 to Eliminate Off-target Activity.
Tetrahedron letters 2021 Bouffard E, Zaro BW, Dix MM, Cravatt B, Wong CH -
Proteomic analysis of young and old mouse hematopoietic stem cells and their progenitors reveals post-transcriptional regulation in stem cells.
eLife 2020 Zaro BW, Noh JJ, Mascetti VL, Demeter J, George B, Zukowska M, Gulati GS, Sinha R, Flynn RA, Banuelos A, Zhang A, Wilkinson AC, Jackson P, Weissman IL -
Metabolic Labeling for the Visualization and Identification of Potentially O-GlcNAc-Modified Proteins.
Current protocols in chemical biology 2020 Pedowitz NJ, Zaro BW, Pratt MR -
O-Acetylated Chemical Reporters of Glycosylation Can Display Metabolism-Dependent Background Labeling of Proteins but Are Generally Reliable Tools for the Identification of Glycoproteins.
Frontiers in chemistry 2020 Darabedian N, Yang B, Ding R, Cutolo G, Zaro BW, Woo CM, Pratt MR -
CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy.
Nature 2019 Barkal AA, Brewer RE, Markovic M, Kowarsky M, Barkal SA, Zaro BW, Krishnan V, Hatakeyama J, Dorigo O, Barkal LJ, Weissman IL -
The Proteome-Wide Potential for Reversible Covalency at Cysteine.
Angewandte Chemie (International ed. in English) 2019 Senkane K, Vinogradova EV, Suciu RM, Crowley VM, Zaro BW, Bradshaw JM, Brameld KA, Cravatt BF -
Dimethyl Fumarate Disrupts Human Innate Immune Signaling by Targeting the IRAK4-MyD88 Complex.
Journal of immunology (Baltimore, Md. : 1950) 2019 Zaro BW, Vinogradova EV, Lazar DC, Blewett MM, Suciu RM, Takaya J, Studer S, de la Torre JC, Casanova JL, Cravatt BF, Teijaro JR -
Azide- and Alkyne-Bearing Metabolic Chemical Reporters of Glycosylation Show Structure-Dependent Feedback Inhibition of the Hexosamine Biosynthetic Pathway.
Chembiochem : a European journal of chemical biology 2018 Walter LA, Batt AR, Darabedian N, Zaro BW, Pratt MR -
Correction to "An Alkyne-Aspirin Chemical Reporter for the Detection of Aspirin-Dependent Protein Modification in Living Cells".
Journal of the American Chemical Society 2018 Bateman LA, Zaro BW, Miller SM, Pratt MR -
The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8.
Journal of the American Chemical Society 2017 Chuh KN, Batt AR, Zaro BW, Darabedian N, Marotta NP, Brennan CK, Amirhekmat A, Pratt MR -
Metabolic Chemical Reporters of Glycans Exhibit Cell-Type-Selective Metabolism and Glycoprotein Labeling.
Chembiochem : a European journal of chemical biology 2017 Batt AR, Zaro BW, Navarro MX, Pratt MR -
The Small Molecule 2-Azido-2-deoxy-glucose Is a Metabolic Chemical Reporter of O-GlcNAc Modifications in Mammalian Cells, Revealing an Unexpected Promiscuity of O-GlcNAc Transferase.
ACS chemical biology 2017 Zaro BW, Batt AR, Chuh KN, Navarro MX, Pratt MR -
Metabolically Labile Fumarate Esters Impart Kinetic Selectivity to Irreversible Inhibitors.
Journal of the American Chemical Society 2016 Zaro BW, Whitby LR, Lum KM, Cravatt BF -
Chemical proteomic map of dimethyl fumarate-sensitive cysteines in primary human T cells.
Science signaling 2016 Blewett MM, Xie J, Zaro BW, Backus KM, Altman A, Teijaro JR, Cravatt BF -
O-GlcNAc modification blocks the aggregation and toxicity of the protein α-synuclein associated with Parkinson's disease.
Nature chemistry 2015 Marotta NP, Lin YH, Lewis YE, Ambroso MR, Zaro BW, Roth MT, Arnold DB, Langen R, Pratt MR -
Chemoproteomics reveals Toll-like receptor fatty acylation.
BMC biology 2014 Chesarino NM, Hach JC, Chen JL, Zaro BW, Rajaram MV, Turner J, Schlesinger LS, Pratt MR, Hang HC, Yount JS -
Changes in metabolic chemical reporter structure yield a selective probe of O-GlcNAc modification.
Journal of the American Chemical Society 2014 Chuh KN, Zaro BW, Piller F, Piller V, Pratt MR -
Chemical reporter for visualizing metabolic cross-talk between carbohydrate metabolism and protein modification.
ACS chemical biology 2014 Zaro BW, Chuh KN, Pratt MR -
Identification of O-GlcNAc modification targets in mouse retinal pericytes: implication of p53 in pathogenesis of diabetic retinopathy.
PloS one 2014 Gurel Z, Zaro BW, Pratt MR, Sheibani N -
An alkyne-aspirin chemical reporter for the detection of aspirin-dependent protein modification in living cells.
Journal of the American Chemical Society 2013 Bateman LA, Zaro BW, Miller SM, Pratt MR -
Incorporation of unnatural sugars for the identification of glycoproteins.
Methods in molecular biology (Clifton, N.J.) 2013 Zaro BW, Hang HC, Pratt MR -
N-Propargyloxycarbamate monosaccharides as metabolic chemical reporters of carbohydrate salvage pathways and protein glycosylation.
Chemical communications (Cambridge, England) 2012 Bateman LA, Zaro BW, Chuh KN, Pratt MR -
Chemical reporters for fluorescent detection and identification of O-GlcNAc-modified proteins reveal glycosylation of the ubiquitin ligase NEDD4-1.
Proceedings of the National Academy of Sciences of the United States of America 2011 Zaro BW, Yang YY, Hang HC, Pratt MR -
Robust in-gel fluorescence detection of mucin-type O-linked glycosylation.
Bioorganic & medicinal chemistry letters 2011 Zaro BW, Bateman LA, Pratt MR -
Precise control of protein concentration in living cells.
Angewandte Chemie (International ed. in English) 2010 Lau HD, Yaegashi J, Zaro BW, Pratt MR