Ashok Nambiar, MD
Professor
Laboratory Medicine
School of Medicine

Clinical interests include diagnostic immunohematology, blood donor safety and transfusion therapy. Research interests include platelet alloimmunization, microbial contamination of blood products, error management and systems approach to transfusion safety.

Awards

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• Faculty Teaching Award, UCSF Dept of Laboratory Medicine, 2011
• Faculty Teaching Award, UCSF Dept of Laboratory Medicine, 2010
• Faculty Teaching Award, UCSF Dept of Laboratory Medicine, 2006
• AABB Baxter Transfusion Medicine Fellow Scholarship Award, AABB, 2004

Publications (24)

Top publication keywords:
Platelet TransfusionCD47 AntigenSepsisBody HeightAntigens, Human PlateletBlood PlateletsEligibility DeterminationMembrane GlycoproteinsPlateletpheresisMultiple MyelomaADP-ribosyl Cyclase 1Donor SelectionBlood Grouping and CrossmatchingThrombocytopeniaIsoantibodies

• Anti-CD38 monoclonal antibody interference with blood compatibility testing: Differentiating isatuximab and daratumumab via functional epitope mapping.
  Transfusion 2022 Chami B, Okuda M, Moayeri M, Pirenne F, Hidaka Y, Nambiar A, Song Z, Bedel O, Zhang B, Hopke J, Deng G, Zhu C, Macé S, Chiron M, Adrian F, Fukao T, Basile FG, Martin T
• Outcomes after ultramassive transfusion in the modern era: An Eastern Association for the Surgery of Trauma multicenter study.
  The journal of trauma and acute care surgery 2021 Matthay ZA, Hellmann ZJ, Callcut RA, Matthay EC, Nunez-Garcia B, Duong W, Nahmias J, LaRiccia AK, Spalding MC, Dalavayi SS, Reynolds JK, Lesch H, Wong YM, Chipman AM, Kozar RA, Penaloza L, Mukherjee K…
• Impact of new myeloma agents on the transfusion laboratory.
  Pathology 2021 Jones AD, Moayeri M, Nambiar A
• Treatment of immunocompromised COVID-19 patients with convalescent plasma.
  Transplant infectious disease : an official journal of the Transplantation Society 2020 Fung M, Nambiar A, Pandey S, Aldrich JM, Teraoka J, Freise C, Roberts J, Chandran S, Hays SR, Bainbridge E, DeVoe C, Roque Gardner A, Yokoe D, Henrich TJ, Babik JM, Chin-Hong P
• Investigating Transfusion-related Sepsis Using Culture-Independent Metagenomic Sequencing.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2020 Crawford E, Kamm J, Miller S, Li LM, Caldera S, Lyden A, Yokoe D, Nichols A, Tran NK, Barnard SE, Conner PM, Nambiar A, Zinter MS, Moayeri M, Serpa PH, Prince BC, Quan J, Sit R, Tan M, Phelps M, …

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• Sepsis from an apheresis platelet contaminated with Acinetobacter calcoaceticus/baumannii complex bacteria and Staphylococcus saprophyticus after pathogen reduction.
  Transfusion 2020 Fridey JL, Stramer SL, Nambiar A, Moayeri M, Bakkour S, Langelier C, Crawford E, Lu T, Lanteri MC, Kamm J, Miller S, Wagner SJ, Benjamin RJ, Busch MP
• Sepsis Attributed to Bacterial Contamination of Platelets Associated with a Potential Common Source - Multiple States, 2018.
  MMWR. Morbidity and mortality weekly report 2019 Jones SA, Jones JM, Leung V, Nakashima AK, Oakeson KF, Smith AR, Hunter R, Kim JJ, Cumming M, McHale E, Young PP, Fridey JL, Kelley WE, Stramer SL, Wagner SJ, West FB, Herron R, Snyder E, Hendrickson …
• Development and Implementation of Real-Time Web-Based Dashboards in a Multisite Transfusion Service.
  Journal of pathology informatics 2019 Woo JS, Suslow P, Thorsen R, Ma R, Bakhtary S, Moayeri M, Nambiar A
• Fatal Sepsis Associated with Bacterial Contamination of Platelets - Utah and California, August 2017.
  MMWR. Morbidity and mortality weekly report 2018 Horth RZ, Jones JM, Kim JJ, Lopansri BK, Ilstrup SJ, Fridey J, Kelley WE, Stramer SL, Nambiar A, Ramirez-Avila L, Nichols A, Garcia W, Oakeson KF, Vlachos N, McAllister G, Hunter R, Nakashima AK, …
• Two septic transfusion reactions presenting as transfusion-related acute lung injury from a split plateletpheresis unit.
  Critical care medicine 2012 Rollins MD, Molofsky AB, Nambiar A, Pandey S, Weiskopf RB, Toy P
• Longitudinal management with crossmatch-compatible platelets for refractory patients: alloimmunization, response to transfusion, and clinical outcomes (CME).
  Transfusion 2012 Wiita AP, Nambiar A
• Transfusion
  Longitudinal management with crossmatch-compatible platelets for refractory patients: alloimmunization, response to transfusion, and clinical outcomes 2012 Arun Wiita and Ashok Nambiar
• Transfusion 2011 2011;51:2573-2582
  Detection of bacterial contamination in pre-storage culture negative apheresis platelets on day of issue with the PGD test 2011 Michael R. Jacobs et al and PGD Study Group.
• The potential impact of new donor height and weight criteria on young donor eligibility and faint or prefaint reaction rates.
  Transfusion 2010 Dunbar N, Katz J, Nambiar A
• HLAMatchmaker-driven analysis of responses to HLA-typed platelet transfusions in alloimmunized thrombocytopenic patients.
  Blood 2005 Nambiar A, Duquesnoy RJ, Adams S, Zhao Y, Oblitas J, Leitman S, Stroncek D, Marincola F
• Chicken Y-box proteins chk-YB-1b and chk-YB-2 repress translation by sequence-specific interaction with single-stranded RNA.
  The Biochemical journal 2000 Swamynathan SK, Nambiar A, Guntaka RV
• Role of single-stranded DNA regions and Y-box proteins in transcriptional regulation of viral and cellular genes.
  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998 Swamynathan SK, Nambiar A, Guntaka RV
• Characterization of the DNA-binding domain of the avian Y-box protein, chkYB-2, and mutational analysis of its single-strand binding motif in the Rous sarcoma virus enhancer.
  Journal of virology 1998 Nambiar A, Swamynathan SK, Kandala JC, Guntaka RV
• Cloning of a novel Y-box homology protein (chkYB-1HP) cDNA lacking the cold-shock domain.
  Biochimica et biophysica acta 1998 Nambiar A, Kandala JC, Svoboda J, Guntaka RV
• Molecular cloning and characterization of a cDNA for the highly conserved HMG-like protein (Pf16) gene of Plasmodium falciparum.
  Biochemical and biophysical research communications 1997 Nambiar A, Kandala JC, Dolan SA, Jensen JB, Guntaka RV
• Chicken YB-2, a Y-box protein, is a potent activator of Rous sarcoma virus long terminal repeat-driven transcription in avian fibroblasts.
  Journal of virology 1997 Swamynathan SK, Nambiar A, Guntaka RV
• Cloning of Rous sarcoma virus enhancer factor genes. II. RSV-EF-II, abundantly expressed in fibroblasts and muscle tissue, binds to an octamer sequence, 5'-GTACCACC-3', in the noncoding strand of RSV enhancer.
  Virology 1996 Cleavinger PJ, Shin BA, Kandala JC, Nambiar A, Swamynathan SK, Guntaka RV
• Host- and tissue-specific factors that interact with the enhancer sequences of Rous sarcoma virus LTR.
  Folia biologica 1994 Guntaka RV, Kandala JC, Shin BA, Nambiar A, Svoboda J, Cleavinger P
• Ulnar nerve inoculation of poliovirus in bonnet monkey: a new primate model to investigate neurovirulence.
  Vaccine 1992 John TJ, Nambiar A, Samuel BU, Rajasingh J