Arthur Charles-Orszag, PhD
Research Specialist II
Howard Hughes Medical Instit
School of Medicine

Publications (16)

Top publication keywords:
Fimbriae ProteinsNanofibersHuman Umbilical Vein Endothelial CellsFimbriae, BacterialActomyosinEvolution, MolecularActinsMembrane GlycoproteinsCell MembraneBacterial AdhesionNeisseria meningitidisBacterial InfectionsArchaeaArchaeal ProteinsSulfolobus acidocaldarius

• De novo designed bright, hyperstable rhodamine binders for fluorescence microscopy.
  bioRxiv : the preprint server for biology 2025 Chen Y, Yserentant K, Hong K, Kuang Y, Bhowmick A, Charles-Orszag A, Lord SJ, Lu L, Hou K, Mann SI, Grimm JB, Lavis LD, Mullins RD, DeGrado WF, Huang B
• Biogenesis, function and evolution of the archaeal S-layer.
  Current opinion in cell biology 2025 Sivabalasarma S, van Wolferen M, Albers SV, Charles-Orszag A
• Archaeal SegAB forms a bipolar structure that promotes chromosome segregation in spherical cells.
  bioRxiv : the preprint server for biology 2025 Charles-Orszag A, Lord SJ, Herrera N, Strauskulage L, Bhowmick A, Goddard T, Wassmer B, van Wolferen M, Asper G, Flis A, Rodriguez J, Redding S, Rosenberg O, Albers SV, Mullins RD
• Adhesion pilus retraction powers twitching motility in the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius.
  Nature communications 2024 Charles-Orszag A, van Wolferen M, Lord SJ, Albers SV, Mullins RD
• Editorial: Molecular Biology of Archaea - 2022.
  Frontiers in microbiology 2024 van Wolferen M, Ithurbide S, Santiago-Martínez MG, Charles-Orszag A

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• Archaeal actins and the origin of a multi-functional cytoskeleton.
  Journal of bacteriology 2024 Charles-Orszag A, Petek-Seoane NA, Mullins RD
• 3D matrix adhesion feedback controls nuclear force coupling to drive invasive cell migration.
  Cell reports 2023 Newman D, Young LE, Waring T, Brown L, Wolanska KI, MacDonald E, Charles-Orszag A, Goult BT, Caswell PT, Sakuma T, Yamamoto T, Machesky LM, Morgan MR, Zech T
• Sulfolobus acidocaldarius adhesion pili power twitching motility in the absence of a dedicated retraction ATPase.
  bioRxiv : the preprint server for biology 2023 Charles-Orszag A, van Wolferen M, Lord SJ, Albers SV, Mullins RD
• TrackMate 7: integrating state-of-the-art segmentation algorithms into tracking pipelines.
  Nature methods 2022 Ershov D, Phan MS, Pylvänäinen JW, Rigaud SU, Le Blanc L, Charles-Orszag A, Conway JRW, Laine RF, Roy NH, Bonazzi D, Duménil G, Jacquemet G, Tinevez JY
• High-Temperature Live-Cell Imaging of Cytokinesis, Cell Motility, and Cell-Cell Interactions in the Thermoacidophilic Crenarchaeon Sulfolobus acidocaldarius.
  Frontiers in microbiology 2021 Charles-Orszag A, Lord SJ, Mullins RD
• Rapid deployment of SARS-CoV-2 testing: The CLIAHUB.
  PLoS pathogens 2020 Crawford ED, Acosta I, Ahyong V, Anderson EC, Arevalo S, Asarnow D, Axelrod S, Ayscue P, Azimi CS, Azumaya CM, Bachl S, Bachmutsky I, Bhaduri A, Brown JB, Batson J, Behnert A, Boileau RM, Bollam SR, …
• Deep mutational scanning of the Neisseria meningitidis major pilin reveals the importance of pilus tip-mediated adhesion.
  The EMBO journal 2019 Kennouche P, Charles-Orszag A, Nishiguchi D, Goussard S, Imhaus AF, Dupré M, Chamot-Rooke J, Duménil G
• Adhesion to nanofibers drives cell membrane remodeling through one-dimensional wetting.
  Nature communications 2018 Charles-Orszag A, Tsai FC, Bonazzi D, Manriquez V, Sachse M, Mallet A, Salles A, Melican K, Staneva R, Bertin A, Millien C, Goussard S, Lafaye P, Shorte S, Piel M, Krijnse-Locker J, Brochard-Wyart F, …
• Microbial pathogenesis meets biomechanics.
  Current opinion in cell biology 2016 Charles-Orszag A, Lemichez E, Tran Van Nhieu G, Duménil G
• Neisseria meningitidis Type IV Pili Composed of Sequence Invariable Pilins Are Masked by Multisite Glycosylation.
  PLoS pathogens 2015 Gault J, Ferber M, Machata S, Imhaus AF, Malosse C, Charles-Orszag A, Millien C, Bouvier G, Bardiaux B, Péhau-Arnaudet G, Klinge K, Podglajen I, Ploy MC, Seifert HS, Nilges M, Chamot-Rooke J, Duménil …
• Early sequence of events triggered by the interaction of Neisseria meningitidis with endothelial cells.
  Cellular microbiology 2013 Soyer M, Charles-Orszag A, Lagache T, Machata S, Imhaus AF, Dumont A, Millien C, Olivo-Marin JC, Duménil G