Ari Green, MD
Professor
Neurology
School of Medicine

Dr. Green is also Medical Director of the UCSF MS and Neuroinflammation Center – one of the largest clinics of its kind in the United States with a broad focus on caring for patients with conditions in which immune dysregulation or inflammation play an important role. The clinic seeks to provide comprehensive, patient-centered care for people living with these diseases with a wide variety of ancillary services for diagnosis, monitoring and supporting patients and their families. Dr. Green’s laboratory is dedicated to the biological validation of potential biomarkers intended to measure remyelination and repair (as well as progression) in MS as a means to accelerate clinical trials for reparative treatments. His major scientific contributions include directing the first successful phase II clinical trial of a remyelinating agent for MS, developing methods for monitoring myelin repair, detailing the histopathological changes in the retina seen in MS, and describing the role of progranulin in the retina along with discovering a previously unknown retinal phenotype in progranulin-related frontotemporal dementia. His lab maintains an active interest in the developing and validating biomarkers for neurodegenerative disease generally and inflammatory diseases of the central nervous system in particular. He also co-directs the Program in Remyelination and Repair with Dr. Jonah Chan as well as the Neurodiagnostics Center in the Department of Neurology.

Dr. Green completed medical school at Duke University School of Medicine in 2001 (during which time he had a Howard Hughes Medical Institute predoctoral fellowship with Drs. Jorge Oksenberg and Stephen L Hauser) and Internship in the Department of Medicine at UCSF in 2002. He completed Residency training at UCSF including Chief Residency in Neurology and post residency fellowships in Neuroimmunology under Dr. Stephen Hauser and Neuro-ophthalmology under Drs. William F. Hoyt and Kimberly Cockerham at UCSF. He then had a visiting fellowship at Queen’s University Belfast under Dame Ingrid Allen in Neuropathology. He was named the first AAN/NMSS Clinician Science Fellow in 2005 and received a Howard Hughes Clinician Scientist award from HHMI. He was named as the Debbie and Andy Rachleff Distinguished Professor of Neurology in 2009 and joined the Department of Ophthalmology at UCSF in 2011. He was a Harry Weaver Neuroscience Scholar and has served as Associate Editor for JAMA Neurology since 2017.

The Division of Neuroimmunology and Glial Biology - since its inception under the leadership of Dr. Stephen Hauser in 1992 - has made major contributions to all aspects of the biology of MS and its treatment including defining the full genetic risk profile for MS, discovering the importance of B cell biology in MS, improving our understanding of adaptive immune processes in inflammatory diseases of the brain and making groundbreaking discoveries in therapeutics for repair and remyelination in MS and other demyelinating diseases. The group continues to be focused on breakthrough developments in the field including microbiome research, glial biology work, and working to uncover the triggers of MS and other inflammatory diseases of the CNS. Under Dr. Green’s leadership, the group has expanded its focus to investigate new methods for understanding infectious and inflammatory diseases of the brain as well as developmental and autoimmune disorders of the CNS that lead to neurological disability. The Division is also a leading force for the education of trainees in clinical care, scientific disciplines and graduate studies in all areas related to our clinical and research mission. We actively train clinical fellows, residents, students and community members in issues of importance to our patients and their families.

• Patient-reported outcome parameters and disability worsening in progressive multiple sclerosis.
  Multiple sclerosis and related disorders 2023 Abdelhak A, Antweiler K, Kowarik MC, Senel M, Havla J, Zettl UK, Kleiter I, Hoshi MM, Skripuletz T, Haarmann A, Stahmann A, Huss A, Gingele S, Krumbholz M, Selge C, Friede T, Ludolph AC, Overell J, …
• Remyelination protects neurons from DLK-mediated neurodegeneration.
  bioRxiv : the preprint server for biology 2023 Duncan GJ, Ingram SD, Emberley K, Hill J, Cordano C, Abdelhak A, McCane M, Jabassini N, Ananth K, Ferrara SJ, Stedelin B, Sivyer B, Aicher SA, Scanlan T, Watkins TA, Mishra A, Nelson J, Green AJ, …
• Retinal Changes After Acute and Late Optic Neuritis in Aquaporin-4 Antibody Seropositive NMOSD.
  Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 2023 Oertel FC, Zimmermann HG, Motamedi S, Bereuter C, Asseyer ES, Chien C, Marignier R, Cobo-Calvo A, Leocani L, Pisa M, Radaelli M, Villoslada P, Sanchez-Dalmau B, Martinez-Lapiscina EH, Lana-Peixoto MA,…
• Attack adjudication in neuromyelitis optica spectrum disorder: Substantiation of criteria by magnetic resonance imaging and biomarkers in N-MOmentum.
  Multiple sclerosis (Houndmills, Basingstoke, England) 2023 Weinshenker BG, Wingerchuk DM, Green AJ, Bennett JL, Kim HJ, Pittock SJ, Fujihara K, Paul F, Cutter G, Marignier R, Aktas O, Hartung HP, She D, Smith M, Rees W, Patterson K, Cimbora D, Katz E, Cree BA
• Challenges and Opportunities for the Promising Biomarker Blood Neurofilament Light Chain.
  JAMA neurology 2023 Abdelhak A, Kuhle J, Green AJ
• Imaging immunomodulatory treatment responses in a multiple sclerosis mouse model using hyperpolarized 13C metabolic MRI.
  Communications medicine 2023 Guglielmetti C, Cordano C, Najac C, Green AJ, Chaumeil MM
• A Predictive Autoantibody Signature in Multiple Sclerosis.
  medRxiv : the preprint server for health sciences 2023 Zamecnik CR, Sowa GM, Abdelhak A, Dandekar R, Bair RD, Wade KJ, Bartley CM, Tubati A, Gomez R, Fouassier C, Gerungan C, Alexander J, Wapniarski AE, Loudermilk RP, Eggers EL, Zorn KC, Ananth K, …
• Prognostic performance of blood neurofilament light chain protein in hospitalized COVID-19 patients without major central nervous system manifestations: an individual participant data meta-analysis.
  Journal of neurology 2023 Abdelhak A, Barba L, Romoli M, Benkert P, Conversi F, D'Anna L, Masvekar RR, Bielekova B, Prudencio M, Petrucelli L, Meschia JF, Erben Y, Furlan R, De Lorenzo R, Mandelli A, Sutter R, Hert L, Epple V,…
• MWF of the corpus callosum is a robust measure of remyelination: Results from the ReBUILD trial.
  Proceedings of the National Academy of Sciences of the United States of America 2023 Caverzasi E, Papinutto N, Cordano C, Kirkish G, Gundel TJ, Zhu A, Akula AV, Boscardin WJ, Neeb H, Henry RG, Chan JR, Green AJ
• Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination.
  The Journal of clinical investigation 2023 Kapell H, Fazio L, Dyckow J, Schwarz S, Cruz-Herranz A, Mayer C, Campos J, D'Este E, Möbius W, Cordano C, Pröbstel AK, Gharagozloo M, Zulji A, Narayanan Naik V, Delank A, Cerina M, Müntefering T, …
• Visually Evoked Potential as Prognostic Biomarker for Neuroaxonal Damage in Multiple Sclerosis From a Multicenter Longitudinal Cohort.
  Neurology(R) neuroimmunology & neuroinflammation 2023 Oertel FC, Krämer J, Motamedi S, Keihani A, Zimmermann HG, Dimitriou NG, Condor-Montes S, Bereuter C, Cordano C, Abdelhak A, Trip A, Aktas O, Meuth SG, Wiendl H, Ruprecht K, Bellmann-Strobl J, Paul F,…
• Diagnostic value of intereye difference metrics for optic neuritis in aquaporin-4 antibody seropositive neuromyelitis optica spectrum disorders.
  Journal of neurology, neurosurgery, and psychiatry 2023 Oertel FC, Zimmermann HG, Motamedi S, Chien C, Aktas O, Albrecht P, Ringelstein M, Dcunha A, Pandit L, Martinez-Lapiscina EH, Sanchez-Dalmau B, Villoslada P, Palace J, Roca-Fernández A, Leite MI, …
• Tailoring a home-based, multidisciplinary deprescribing intervention through clinicians and community-dwelling older adults.
  Journal of the American Geriatrics Society 2022 Lee JW, Boyd CM, Leff B, Green A, Hornstein E, LaFave S, Seau Q, Nkodo A, Kachur S, Williams N, Riser T, Szanton SL
• Validating visual evoked potentials as a preclinical, quantitative biomarker for remyelination efficacy.
  Brain : a journal of neurology 2022 Cordano C, Sin JH, Timmons G, Yiu HH, Stebbins K, Guglielmetti C, Cruz-Herranz A, Xin W, Lorrain D, Chan JR, Green AJ
• Differences in Age-related Retinal and Cortical Atrophy Rates in Multiple Sclerosis.
  Neurology 2022 Cordano C, Nourbakhsh B, Yiu HH, Papinutto N, Caverzasi E, Abdelhak A, Oertel FC, Beaudry-Richard A, Santaniello A, Sacco S, Bennett DJ, Gomez A, Sigurdson CJ, Hauser SL, Magliozzi R, Cree BAC, Henry …
• Longitudinal Retinal Changes in MOGAD.
  Annals of neurology 2022 Oertel FC, Sotirchos ES, Zimmermann HG, Motamedi S, Specovius S, Asseyer ES, Chien C, Cook L, Vasileiou E, Filippatou A, Calabresi PA, Saidha S, Pandit L, D'Cunha A, Outteryck O, Zéphir H, Pittock S, …
• Retinal arteriolar parameters as a surrogate marker of intracranial vascular pathology.
  Alzheimer's & dementia (Amsterdam, Netherlands) 2022 Abdelhak A, Solomon I, Montes SC, Saias A, Cordano C, Asken B, Fonseca C, Oertel FC, Arfanakis K, Staffaroni AM, Kramer JH, Geschwind M, Miller BL, Elahi FM, Green AJ
• Plasma neurofilament light chain levels suggest neuroaxonal stability following therapeutic remyelination in people with multiple sclerosis.
  Journal of neurology, neurosurgery, and psychiatry 2022 Abdelhak A, Cordano C, Boscardin WJ, Caverzasi E, Kuhle J, Chan B, Gelfand JM, Yiu HH, Oertel FC, Beaudry-Richard A, Condor Montes S, Oksenberg JR, Lario Lago A, Boxer A, Rojas-Martinez JC, Elahi FM, …
• Transitioning From S1P Receptor Modulators to B Cell-Depleting Therapies in Multiple Sclerosis: Clinical, Radiographic, and Laboratory Data.
  Neurology(R) neuroimmunology & neuroinflammation 2022 Rowles WM, Hsu WY, McPolin K, Li A, Merrill S, Guo CY, Green AJ, Gelfand JM, Bove RM
• Reply to "Interpretation of Longitudinal Changes of the Inner Nuclear Layer in MS".
  Annals of neurology 2022 Cordano C, Yiu HH, Abdelhak A, Beaudry-Richard A, Oertel FC, Green AJ
• Reply to "Spinal Cord Atrophy Is a Preclinical Marker of Progressive MS".
  Annals of neurology 2022 Bischof A, Papinutto N, Keshavan A, Rajesh A, Kirkish G, Zhang X, Mallott JM, Asteggiano C, Sacco S, Gundel TJ, Zhao C, Stern WA, Caverzasi E, Zhou Y, Gomez R, Ragan NR, Santaniello A, Zhu AH, Juwono …
• A hormonal therapy for menopausal women with MS: A phase Ib/IIa randomized controlled trial.
  Multiple sclerosis and related disorders 2022 Bove R, Anderson A, Rowles W, Rankin KA, Hills NK, Carleton M, Cooper J, Cree BAC, Gelfand JM, Graves JS, Henry RG, Krysko KM, Rush G, Zamvil SS, Joffe H, Chan JR, Green AJ
• Blood GFAP as an emerging biomarker in brain and spinal cord disorders.
  Nature reviews. Neurology 2022 Abdelhak A, Foschi M, Abu-Rumeileh S, Yue JK, D'Anna L, Huss A, Oeckl P, Ludolph AC, Kuhle J, Petzold A, Manley GT, Green AJ, Otto M, Tumani H
• Characterizing Fixational Eye Motion Variance Over Time as Recorded by the Tracking Scanning Laser Ophthalmoscope.
  Translational vision science & technology 2022 Condor Montes SY, Bennett D, Bensinger E, Rani L, Sherkat Y, Zhao C, Helft Z, Roorda A, Green AJ, Sheehy CK
• Spinal Cord Atrophy Predicts Progressive Disease in Relapsing Multiple Sclerosis.
  Annals of neurology 2022 Bischof A, Papinutto N, Keshavan A, Rajesh A, Kirkish G, Zhang X, Mallott JM, Asteggiano C, Sacco S, Gundel TJ, Zhao C, Stern WA, Caverzasi E, Zhou Y, Gomez R, Ragan NR, Santaniello A, Zhu AH, Juwono …
• Socioeconomic disadvantage in multiple sclerosis: does inequality act on the substrate for disability?
  Brain : a journal of neurology 2021 Green AJ
• Interocular Difference in Retinal Nerve Fiber Layer Thickness Predicts Optic Neuritis in Pediatric-Onset Multiple Sclerosis.
  Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 2021 Waldman AT, Benson L, Sollee JR, Lavery AM, Liu GW, Green AJ, Waubant E, Heidary G, Conger D, Graves J, Greenberg B
• Optical coherence tomography in multiple sclerosis: A 3-year prospective multicenter study.
  Annals of clinical and translational neurology 2021 Paul F, Calabresi PA, Barkhof F, Green AJ, Kardon R, Sastre-Garriga J, Schippling S, Vermersch P, Saidha S, Gerendas BS, Schmidt-Erfurth U, Agoropoulou C, Zhang Y, Seifer G, Petzold A
• AQP4-IgG-seronegative patient outcomes in the N-MOmentum trial of inebilizumab in neuromyelitis optica spectrum disorder.
  Multiple sclerosis and related disorders 2021 Marignier R, Pittock SJ, Paul F, Kim HJ, Bennett JL, Weinshenker BG, Wingerchuk DM, Green AJ, Fujihara K, Cutter G, Aktas O, Hartung HP, Drappa J, Ratchford JN, She D, Smith M, Rees W, Cimbora D, Katz…
• Astrocytic outer retinal layer thinning is not a feature in AQP4-IgG seropositive neuromyelitis optica spectrum disorders.
  Journal of neurology, neurosurgery, and psychiatry 2021 Lu A, Zimmermann HG, Specovius S, Motamedi S, Chien C, Bereuter C, Lana-Peixoto MA, Fontenelle MA, Ashtari F, Kafieh R, Dehghani A, Pourazizi M, Pandit L, D'Cunha A, Kim HJ, Hyun JW, Jung SK, Leocani …
• Retinal Optical Coherence Tomography in Neuromyelitis Optica.
  Neurology(R) neuroimmunology & neuroinflammation 2021 Oertel FC, Specovius S, Zimmermann HG, Chien C, Motamedi S, Bereuter C, Cook L, Lana Peixoto MA, Fontanelle MA, Kim HJ, Hyun JW, Palace J, Roca-Fernandez A, Leite MI, Sharma S, Ashtari F, Kafieh R, …
• Distinctive waves of innate immune response in the retina in experimental autoimmune encephalomyelitis.
  JCI insight 2021 Cruz-Herranz A, Oertel FC, Kim K, Cantó E, Timmons G, Sin JH, Devereux M, Baker N, Michel B, Schubert RD, Rani L, Cordano C, Baranzini SE, Green AJ
• Artificial intelligence extension of the OSCAR-IB criteria.
  Annals of clinical and translational neurology 2021 Petzold A, Albrecht P, Balcer L, Bekkers E, Brandt AU, Calabresi PA, Deborah OG, Graves JS, Green A, Keane PA, Nij Bijvank JA, Sander JW, Paul F, Saidha S, Villoslada P, Wagner SK, Yeh EA, IMSVISUAL, …
• Retinal imaging demonstrates reduced capillary density in clinically unimpaired APOE ε4 gene carriers.
  Alzheimer's & dementia (Amsterdam, Netherlands) 2021 Elahi FM, Ashimatey SB, Bennett DJ, Walters SM, La Joie R, Jiang X, Wolf A, Cobigo Y, Staffaroni AM, Rosen HJ, Miller BL, Rabinovici GD, Kramer JH, Green AJ, Kashani AH
• APOSTEL 2.0 Recommendations for Reporting Quantitative Optical Coherence Tomography Studies.
  Neurology 2021 Aytulun A, Cruz-Herranz A, Aktas O, Balcer LJ, Balk L, Barboni P, Blanco AA, Calabresi PA, Costello F, Sanchez-Dalmau B, DeBuc DC, Feltgen N, Finger RP, Frederiksen JL, Frohman E, Frohman T, Garway-…
• Disability Outcomes in the N-MOmentum Trial of Inebilizumab in Neuromyelitis Optica Spectrum Disorder.
  Neurology(R) neuroimmunology & neuroinflammation 2021 Marignier R, Bennett JL, Kim HJ, Weinshenker BG, Pittock SJ, Wingerchuk D, Fujihara K, Paul F, Cutter GR, Green AJ, Aktas O, Hartung HP, Lublin FD, Williams IM, Drappa J, She D, Cimbora D, Rees W, …
• Sensitivity analysis of the primary endpoint from the N-MOmentum study of inebilizumab in NMOSD.
  Multiple sclerosis (Houndmills, Basingstoke, England) 2021 Cree BA, Bennett JL, Kim HJ, Weinshenker BG, Pittock SJ, Wingerchuk D, Fujihara K, Paul F, Cutter GR, Marignier R, Green AJ, Aktas O, Hartung HP, Williams IM, Drappa J, She D, Cimbora D, Rees W, …
• Underutilization of physical therapy for symptomatic women with MS during and following pregnancy.
  Multiple sclerosis and related disorders 2020 Block VJ, Mestas O, Anderson A, Singh J, Wylie L, Guo CY, Green AJ, Gelfand JM, Bove R
• Retinal INL Thickness in Multiple Sclerosis: A Mere Marker of Neurodegeneration?
  Annals of neurology 2020 Cordano C, Yiu HH, Oertel FC, University of California, San Francisco MS-EPIC Team, Gelfand JM, Hauser SL, Cree BAC, Green AJ
• Neurite Orientation Dispersion and Density Imaging for Assessing Acute Inflammation and Lesion Evolution in MS.
  AJNR. American journal of neuroradiology 2020 Sacco S, Caverzasi E, Papinutto N, Cordano C, Bischof A, Gundel T, Cheng S, Asteggiano C, Kirkish G, Mallott J, Stern WA, Bastianello S, Bove RM, Gelfand JM, Goodin DS, Green AJ, Waubant E, Wilson MR,…
• Author Correction: Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.
  Nature immunology 2020 Mendiola AS, Ryu JK, Bardehle S, Meyer-Franke A, Ang KK, Wilson C, Baeten KM, Hanspers K, Merlini M, Thomas S, Petersen MA, Williams A, Thomas R, Rafalski VA, Meza-Acevedo R, Tognatta R, Yan Z, Pfaff …
• Importance of Not MSing Cerebral White Matter Disease in Patients with Inflammatory Bowel Disease.
  Digestive diseases and sciences 2020 Regner EH, Green AJ, Bain JL, Kattah MG, Mahadevan U
• A pathogenic and clonally expanded B cell transcriptome in active multiple sclerosis.
  Proceedings of the National Academy of Sciences of the United States of America 2020 Ramesh A, Schubert RD, Greenfield AL, Dandekar R, Loudermilk R, Sabatino JJ, Koelzer MT, Tran EB, Koshal K, Kim K, Pröbstel AK, Banerji D, University of California, San Francisco MS-EPIC Team, Guo CY,…
• Imaging correlates of visual function in multiple sclerosis.
  PloS one 2020 Caverzasi E, Cordano C, Zhu AH, Zhao C, Bischof A, Kirkish G, Bennett DJ, Devereux M, Baker N, Inman J, Yiu HH, Papinutto N, Gelfand JM, Cree BAC, Hauser SL, Henry RG, Green AJ
• The Spectrum of Neurologic Disease in the Severe Acute Respiratory Syndrome Coronavirus 2 Pandemic Infection: Neurologists Move to the Frontlines.
  JAMA neurology 2020 Pleasure SJ, Green AJ, Josephson SA
• Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.
  Nature immunology 2020 Mendiola AS, Ryu JK, Bardehle S, Meyer-Franke A, Ang KK, Wilson C, Baeten KM, Hanspers K, Merlini M, Thomas S, Petersen MA, Williams A, Thomas R, Rafalski VA, Meza-Acevedo R, Tognatta R, Yan Z, Pfaff …
• Protective effects of 4-aminopyridine in experimental optic neuritis and multiple sclerosis.
  Brain : a journal of neurology 2020 Dietrich M, Koska V, Hecker C, Göttle P, Hilla AM, Heskamp A, Lepka K, Issberner A, Hallenberger A, Baksmeier C, Steckel J, Balk L, Knier B, Korn T, Havla J, Martínez-Lapiscina EH, Solà-Valls N, …
• Fixational microsaccades: A quantitative and objective measure of disability in multiple sclerosis.
  Multiple sclerosis (Houndmills, Basingstoke, England) 2020 Sheehy CK, Bensinger ES, Romeo A, Rani L, Stepien-Bernabe N, Shi B, Helft Z, Putnam N, Cordano C, Gelfand JM, Bove R, Stevenson SB, Green AJ
• Monitoring retinal changes with optical coherence tomography predicts neuronal loss in experimental autoimmune encephalomyelitis.
  Journal of neuroinflammation 2019 Cruz-Herranz A, Dietrich M, Hilla AM, Yiu HH, Levin MH, Hecker C, Issberner A, Hallenberger A, Cordano C, Lehmann-Horn K, Balk LJ, Aktas O, Ingwersen J, von Gall C, Hartung HP, Zamvil SS, Fischer D, …
• Inebilizumab for the treatment of neuromyelitis optica spectrum disorder (N-MOmentum): a double-blind, randomised placebo-controlled phase 2/3 trial.
  Lancet (London, England) 2019 Cree BAC, Bennett JL, Kim HJ, Weinshenker BG, Pittock SJ, Wingerchuk DM, Fujihara K, Paul F, Cutter GR, Marignier R, Green AJ, Aktas O, Hartung HP, Lublin FD, Drappa J, Barron G, Madani S, Ratchford …
• Early complement genes are associated with visual system degeneration in multiple sclerosis.
  Brain : a journal of neurology 2019 Fitzgerald KC, Kim K, Smith MD, Aston SA, Fioravante N, Rothman AM, Krieger S, Cofield SS, Kimbrough DJ, Bhargava P, Saidha S, Whartenby KA, Green AJ, Mowry EM, Cutter GR, Lublin FD, Baranzini SE, De …
• Lessons from an unsuccessful therapeutic trial.
  The Lancet. Neurology 2019 Green AJ
• Personalizing medical care for patients with MS: Monitoring brainstem damage by infrared oculography.
  Neurology 2019 Villoslada P, Green AJ, Galetta S
• Silent progression in disease activity-free relapsing multiple sclerosis.
  Annals of neurology 2019 University of California, San Francisco MS-EPIC Team, Cree BAC, Hollenbach JA, Bove R, Kirkish G, Sacco S, Caverzasi E, Bischof A, Gundel T, Zhu AH, Papinutto N, Stern WA, Bevan C, Romeo A, Goodin DS,…
• Association of Continuous Assessment of Step Count by Remote Monitoring With Disability Progression Among Adults With Multiple Sclerosis.
  JAMA network open 2019 Block VJ, Bove R, Zhao C, Garcha P, Graves J, Romeo AR, Green AJ, Allen DD, Hollenbach JA, Olgin JE, Marcus GM, Pletcher MJ, Cree BAC, Gelfand JM
• Potential Benefits of Early Aggressive Treatment in Multiple Sclerosis.
  JAMA neurology 2019 Green AJ
• Selective Estrogen Receptor Modulators Enhance CNS Remyelination Independent of Estrogen Receptors.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Rankin KA, Mei F, Kim K, Shen YA, Mayoral SR, Desponts C, Lorrain DS, Green AJ, Baranzini SE, Chan JR, Bove R
• pRNFL as a marker of disability worsening in the medium/long term in patients with MS.
  Neurology(R) neuroimmunology & neuroinflammation 2018 Cordano C, Nourbakhsh B, Devereux M, Damotte V, Bennett D, Hauser SL, Cree BAC, Gelfand JM, Green AJ
• Methods to Assess Ocular Motor Dysfunction in Multiple Sclerosis.
  Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 2018 Sheehy CK, Beaudry-Richard A, Bensinger E, Theis J, Green AJ
• Prion Seeds Distribute throughout the Eyes of Sporadic Creutzfeldt-Jakob Disease Patients.
  mBio 2018 Orrù CD, Soldau K, Cordano C, Llibre-Guerra J, Green AJ, Sanchez H, Groveman BR, Edland SD, Safar JG, Lin JH, Caughey B, Geschwind MD, Sigurdson CJ
• Clinic to in-home telemedicine reduces barriers to care for patients with MS or other neuroimmunologic conditions.
  Neurology(R) neuroimmunology & neuroinflammation 2018 Bove R, Garcha P, Bevan CJ, Crabtree-Hartman E, Green AJ, Gelfand JM
• Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity.
  eLife 2018 Schirmer L, Möbius W, Zhao C, Cruz-Herranz A, Ben Haim L, Cordano C, Shiow LR, Kelley KW, Sadowski B, Timmons G, Pröbstel AK, Wright JN, Sin JH, Devereux M, Morrison DE, Chang SM, Sabeur K, Green AJ, …
• Toward a low-cost, in-home, telemedicine-enabled assessment of disability in multiple sclerosis.
  Multiple sclerosis (Houndmills, Basingstoke, England) 2018 Bove R, Bevan C, Crabtree E, Zhao C, Gomez R, Garcha P, Morrissey J, Dierkhising J, Green AJ, Hauser SL, Cree BA, Wallin MT, Gelfand JM
• Chronic Meningitis Investigated via Metagenomic Next-Generation Sequencing.
  JAMA neurology 2018 Wilson MR, O'Donovan BD, Gelfand JM, Sample HA, Chow FC, Betjemann JP, Shah MP, Richie MB, Gorman MP, Hajj-Ali RA, Calabrese LH, Zorn KC, Chow ED, Greenlee JE, Blum JH, Green G, Khan LM, Banerji D, …
• Reduced contrast sensitivity among older women is associated with increased risk of cognitive impairment.
  Annals of neurology 2018 Ward ME, Gelfand JM, Lui LY, Ou Y, Green AJ, Stone K, Pedula KL, Cummings SR, Yaffe K
• OCT is an alternative to MRI for monitoring MS - Commentary.
  Multiple sclerosis (Houndmills, Basingstoke, England) 2018 Green AJ
• Rituximab before and during pregnancy: A systematic review, and a case series in MS and NMOSD.
  Neurology(R) neuroimmunology & neuroinflammation 2018 Das G, Damotte V, Gelfand JM, Bevan C, Cree BAC, Do L, Green AJ, Hauser SL, Bove R
• Multicenter reliability of semiautomatic retinal layer segmentation using OCT.
  Neurology(R) neuroimmunology & neuroinflammation 2018 Oberwahrenbrock T, Traber GL, Lukas S, Gabilondo I, Nolan R, Songster C, Balk L, Petzold A, Paul F, Villoslada P, Brandt AU, Green AJ, Schippling S
• Harnessing electronic medical records to advance research on multiple sclerosis.
  Multiple sclerosis (Houndmills, Basingstoke, England) 2018 Damotte V, Lizée A, Tremblay M, Agrawal A, Khankhanian P, Santaniello A, Gomez R, Lincoln R, Tang W, Chen T, Lee N, Villoslada P, Hollenbach JA, Bevan CD, Graves J, Bove R, Goodin DS, Green AJ, …
• Combating the Spread of Ineffective Medical Procedures: A Lesson Learned From Multiple Sclerosis.
  JAMA neurology 2018 Green AJ, Kamel H, Josephson SA
• Cell-based therapeutic strategies for multiple sclerosis.
  Brain : a journal of neurology 2017 Scolding NJ, Pasquini M, Reingold SC, Cohen JA, International Conference on Cell-Based Therapies for Multiple Sclerosis, International Conference on Cell-Based Therapies for Multiple Sclerosis, …
• Infliximab for the treatment of CNS sarcoidosis: A multi-institutional series.
  Neurology 2017 Gelfand JM, Bradshaw MJ, Stern BJ, Clifford DB, Wang Y, Cho TA, Koth LL, Hauser SL, Dierkhising J, Vu N, Sriram S, Moses H, Bagnato F, Kaufmann JA, Ammah DJ, Yohannes TH, Hamblin MJ, Venna N, Green AJ…
• Clemastine fumarate as a remyelinating therapy for multiple sclerosis (ReBUILD): a randomised, controlled, double-blind, crossover trial.
  Lancet (London, England) 2017 Green AJ, Gelfand JM, Cree BA, Bevan C, Boscardin WJ, Mei F, Inman J, Arnow S, Devereux M, Abounasr A, Nobuta H, Zhu A, Friessen M, Gerona R, von Büdingen HC, Henry RG, Hauser SL, Chan JR
• Remyelinating Pharmacotherapies in Multiple Sclerosis.
  Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2017 Bove RM, Green AJ
• Systematic integration of biomedical knowledge prioritizes drugs for repurposing.
  eLife 2017 Himmelstein DS, Lizee A, Hessler C, Brueggeman L, Chen SL, Hadley D, Green A, Khankhanian P, Baranzini SE
• Retinal layer segmentation in multiple sclerosis: a systematic review and meta-analysis.
  The Lancet. Neurology 2017 Petzold A, Balcer LJ, Calabresi PA, Costello F, Frohman TC, Frohman EM, Martinez-Lapiscina EH, Green AJ, Kardon R, Outteryck O, Paul F, Schippling S, Vermersch P, Villoslada P, Balk LJ, ERN-EYE …
• Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4.
  Journal of visualized experiments : JoVE 2017 Sagan SA, Cruz-Herranz A, Spencer CM, Ho PP, Steinman L, Green AJ, Sobel RA, Zamvil SS
• T cells targeting neuromyelitis optica autoantigen aquaporin-4 cause paralysis and visual system injury.
  Journal of nature and science 2017 Cruz-Herranz A, Sagan SA, Sobel RA, Green AJ, Zamvil SS
• Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis.
  Science translational medicine 2017 Ward ME, Chen R, Huang HY, Ludwig C, Telpoukhovskaia M, Taubes A, Boudin H, Minami SS, Reichert M, Albrecht P, Gelfand JM, Cruz-Herranz A, Cordano C, Alavi MV, Leslie S, Seeley WW, Miller BL, Bigio E,…
• Retinal thinning is uniquely associated with medial temporal lobe atrophy in neurologically normal older adults.
  Neurobiology of aging 2016 Casaletto KB, Ward ME, Baker NS, Bettcher BM, Gelfand JM, Li Y, Chen R, Dutt S, Miller B, Kramer JH, Green AJ
• Tolerance checkpoint bypass permits emergence of pathogenic T cells to neuromyelitis optica autoantigen aquaporin-4.
  Proceedings of the National Academy of Sciences of the United States of America 2016 Sagan SA, Winger RC, Cruz-Herranz A, Nelson PA, Hagberg S, Miller CN, Spencer CM, Ho PP, Bennett JL, Levy M, Levin MH, Verkman AS, Steinman L, Green AJ, Anderson MS, Sobel RA, Zamvil SS
• Whole-body positional manipulators for ocular imaging of anaesthetised mice and rats: a do-it-yourself guide.
  BMJ open ophthalmology 2016 Dietrich M, Cruz-Herranz A, Yiu H, Aktas O, Brandt AU, Hartung HP, Green A, Albrecht P
• Accelerated remyelination during inflammatory demyelination prevents axonal loss and improves functional recovery.
  eLife 2016 Mei F, Lehmann-Horn K, Shen YA, Rankin KA, Stebbins KJ, Lorrain DS, Pekarek K, A Sagan S, Xiao L, Teuscher C, von Büdingen HC, Wess J, Lawrence JJ, Green AJ, Fancy SP, Zamvil SS, Chan JR
• Long-term evolution of multiple sclerosis disability in the treatment era.
  Annals of neurology 2016 University of California, San Francisco MS-EPIC Team:, Cree BA, Gourraud PA, Oksenberg JR, Bevan C, Crabtree-Hartman E, Gelfand JM, Goodin DS, Graves J, Green AJ, Mowry E, Okuda DT, Pelletier D, von …
• Identification of the Kappa-Opioid Receptor as a Therapeutic Target for Oligodendrocyte Remyelination.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Mei F, Mayoral SR, Nobuta H, Wang F, Desponts C, Lorrain DS, Xiao L, Green AJ, Rowitch D, Whistler J, Chan JR
• Sex differences and subclinical retinal injury in pediatric-onset MS.
  Multiple sclerosis (Houndmills, Basingstoke, England) 2016 Graves JS, Chohan H, Cedars B, Arnow S, Yiu H, Waubant E, Green A
• The APOSTEL recommendations for reporting quantitative optical coherence tomography studies.
  Neurology 2016 Cruz-Herranz A, Balk LJ, Oberwahrenbrock T, Saidha S, Martinez-Lapiscina EH, Lagreze WA, Schuman JS, Villoslada P, Calabresi P, Balcer L, Petzold A, Green AJ, Paul F, Brandt AU, Albrecht P, IMSVISUAL …
• Timing of retinal neuronal and axonal loss in MS: a longitudinal OCT study.
  Journal of neurology 2016 Balk LJ, Cruz-Herranz A, Albrecht P, Arnow S, Gelfand JM, Tewarie P, Killestein J, Uitdehaag BM, Petzold A, Green AJ
• Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: a cohort study.
  The Lancet. Neurology 2016 Martinez-Lapiscina EH, Arnow S, Wilson JA, Saidha S, Preiningerova JL, Oberwahrenbrock T, Brandt AU, Pablo LE, Guerrieri S, Gonzalez I, Outteryck O, Mueller AK, Albrecht P, Chan W, Lukas S, Balk LJ, …
• The challenge of comorbidity in clinical trials for multiple sclerosis.
  Neurology 2016 Marrie RA, Miller A, Sormani MP, Thompson A, Waubant E, Trojano M, O'Connor P, Reingold S, Cohen JA, attendees of the International Workshop on Comorbidity in Multiple Sclerosis
• Recommendations for observational studies of comorbidity in multiple sclerosis.
  Neurology 2016 Marrie RA, Miller A, Sormani MP, Thompson A, Waubant E, Trojano M, O'Connor P, Fiest K, Reider N, Reingold S, Cohen JA, attendees of the International Workshop on Comorbidity in Multiple Sclerosis
• Association Between Thoracic Spinal Cord Gray Matter Atrophy and Disability in Multiple Sclerosis.
  JAMA neurology 2015 Schlaeger R, Papinutto N, Zhu AH, Lobach IV, Bevan CJ, Bucci M, Castellano A, Gelfand JM, Graves JS, Green AJ, Jordan KM, Keshavan A, Panara V, Stern WA, von Büdingen HC, Waubant E, Goodin DS, Cree BA…
• Retinal damage and vision loss in African American multiple sclerosis patients.
  Annals of neurology 2015 Kimbrough DJ, Sotirchos ES, Wilson JA, Al-Louzi O, Conger A, Conger D, Frohman TC, Saidha S, Green AJ, Frohman EM, Balcer LJ, Calabresi PA
• Encephalitis of unclear origin diagnosed by brain biopsy: a diagnostic challenge.
  JAMA neurology 2015 Gelfand JM, Genrich G, Green AJ, Tihan T, Cree BA
• The best basic science paper in MS in 2013: Antimuscarinic therapies in remyelination.
  Multiple sclerosis (Houndmills, Basingstoke, England) 2014 Green AJ
• Precision medicine in chronic disease management: The multiple sclerosis BioScreen.
  Annals of neurology 2014 Gourraud PA, Henry RG, Cree BA, Crane JC, Lizee A, Olson MP, Santaniello AV, Datta E, Zhu AH, Bevan CJ, Gelfand JM, Graves JS, Goodin DS, Green AJ, von Büdingen HC, Waubant E, Zamvil SS, Crabtree-…
• Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD.
  The Journal of experimental medicine 2014 Ward ME, Taubes A, Chen R, Miller BL, Sephton CF, Gelfand JM, Minami S, Boscardin J, Martens LH, Seeley WW, Yu G, Herz J, Filiano AJ, Arrant AE, Roberson ED, Kraft TW, Farese RV, Green A, Gan L
• Spinal cord gray matter atrophy correlates with multiple sclerosis disability.
  Annals of neurology 2014 Schlaeger R, Papinutto N, Panara V, Bevan C, Lobach IV, Bucci M, Caverzasi E, Gelfand JM, Green AJ, Jordan KM, Stern WA, von Büdingen HC, Waubant E, Zhu AH, Goodin DS, Cree BA, Hauser SL, Henry RG
• Magnetic resonance imaging correlates of clinical outcomes in early multiple sclerosis.
  Multiple sclerosis and related disorders 2014 Maghzi AH, Revirajan N, Julian LJ, Spain R, Mowry EM, Liu S, Jin C, Green AJ, McCulloch CE, Pelletier D, Waubant E
• Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis.
  Nature medicine 2014 Mei F, Fancy SPJ, Shen YA, Niu J, Zhao C, Presley B, Miao E, Lee S, Mayoral SR, Redmond SA, Etxeberria A, Xiao L, Franklin RJM, Green A, Hauser SL, Chan JR
• Retinal architecture and mfERG: Optic nerve head component response characteristics in MS.
  Neurology 2014 Schnurman ZS, Frohman TC, Beh SC, Conger D, Conger A, Saidha S, Galetta S, Calabresi PA, Green AJ, Balcer LJ, Frohman EM
• Reply: Microcysts in the inner nuclear layer from optic atrophy are caused by retrograde trans-synaptic degeneration combined with vitreous traction on the retinal surface.
  Brain : a journal of neurology 2013 Green AJ, Schwartz D, Gelfand J
• Optic nerve head component responses of the multifocal electroretinogram in MS.
  Neurology 2013 Frohman TC, Beh SC, Saidha S, Schnurman Z, Conger D, Conger A, Ratchford JN, Lopez C, Galetta SL, Calabresi PA, Balcer LJ, Green AJ, Frohman EM
• Microcystic inner nuclear layer abnormalities and neuromyelitis optica.
  JAMA neurology 2013 Gelfand JM, Cree BA, Nolan R, Arnow S, Green AJ
• Reply: Microcystic macular degeneration from optic neuropathy: not inflammatory, not trans-synaptic degeneration.
  Brain : a journal of neurology 2013 Gelfand JM, Green AJ
• Getting beyond the ganglion cell: morphometric adjustments for retinal optical coherence tomography in multiple sclerosis.
  JAMA neurology 2013 Green AJ
• Fingolimod treatment in multiple sclerosis leads to increased macular volume.
  Neurology 2012 Nolan R, Gelfand JM, Green AJ
• Microcystic macular oedema, thickness of the inner nuclear layer of the retina, and disease characteristics in multiple sclerosis: a retrospective study.
  The Lancet. Neurology 2012 Saidha S, Sotirchos ES, Ibrahim MA, Crainiceanu CM, Gelfand JM, Sepah YJ, Ratchford JN, Oh J, Seigo MA, Newsome SD, Balcer LJ, Frohman EM, Green AJ, Nguyen QD, Calabresi PA
• Retinal axonal loss begins early in the course of multiple sclerosis and is similar between progressive phenotypes.
  PloS one 2012 Gelfand JM, Goodin DS, Boscardin WJ, Nolan R, Cuneo A, Green AJ
• Microcystic macular oedema in multiple sclerosis is associated with disease severity.
  Brain : a journal of neurology 2012 Gelfand JM, Nolan R, Schwartz DM, Graves J, Green AJ
• Will the real optic nerve sheath please stand up?
  Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 2012 Teismann NA, Lenaghan P, Stein J, Green A
• Switching multiple sclerosis patients with breakthrough disease to second-line therapy.
  PloS one 2011 Castillo-Trivino T, Mowry EM, Gajofatto A, Chabas D, Crabtree-Hartman E, Cree BA, Goodin DS, Green AJ, Okuda DT, Pelletier D, Zamvil SS, Vittinghoff E, Waubant E
• Heterogeneous patterns of tissue injury in NARP syndrome.
  Journal of neurology 2010 Gelfand JM, Duncan JL, Racine CA, Gillum LA, Chin CT, Zhang Y, Zhang Q, Wong LJ, Roorda A, Green AJ
• Optical coherence tomography: a sign of the times.
  Neurology 2010 Green AJ
• Optical coherence tomography in multiple sclerosis: a systematic review and meta-analysis.
  The Lancet. Neurology 2010 Petzold A, de Boer JF, Schippling S, Vermersch P, Kardon R, Green A, Calabresi PA, Polman C
• Ocular pathology in multiple sclerosis: retinal atrophy and inflammation irrespective of disease duration.
  Brain : a journal of neurology 2010 Green AJ, McQuaid S, Hauser SL, Allen IV, Lyness R
• Understanding pseudo: the symptoms are real, the cause is unclear.
  Neurology 2009 Green AJ
• Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.
  Human molecular genetics 2008 Baranzini SE, Wang J, Gibson RA, Galwey N, Naegelin Y, Barkhof F, Radue EW, Lindberg RL, Uitdehaag BM, Johnson MR, Angelakopoulou A, Hall L, Richardson JC, Prinjha RK, Gass A, Geurts JJ, Kragt J, …
• Pediatric multiple sclerosis.
  NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 2006 Chabas D, Green AJ, Waubant E
• Progressive multifocal leukoencephalopathy in a patient treated with natalizumab.
  The New England journal of medicine 2005 Langer-Gould A, Atlas SW, Green AJ, Bollen AW, Pelletier D