Arantxa Cebrian Silla, PhD
Associate Specialist
Neurological Surgery
School of Medicine

Education & Training

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• PhD Neurosciences University of Valencia 2017
• MSc Neurosciences University of Valencia 2011
• BSc Biological Sciences University of Valencia 2010

Publications (28)

Top publication keywords:
Adult Stem CellsTranscriptomeVascular Cell Adhesion Molecule-1Endothelial CellsNeural Stem CellsAstrocytesNeurogenesisNeovascularization, PhysiologicSpinal CordMedian EminenceStem Cell NicheNuclear EnvelopeEpendymoglial CellsEpendymaLateral Ventricles

• Prdm16 regulates the postnatal fate of embryonic radial glia via Vcam1-dependent mechanisms.
  Nature communications 2025 Li J, Godoy MI, Lu Y, Zhang AJ, Diamante G, Rathbun E, Tian M, Ahn IS, Cebrian-Silla A, Alvarez-Buylla A, Yang X, Novitch BG, Carmichael ST, Zhang Y
• Neural stem cell relay from B1 to B2 cells in the adult mouse ventricular-subventricular zone.
  Cell reports 2025 Cebrian-Silla A, Nascimento MA, Mancia W, Gonzalez-Granero S, Romero-Rodriguez R, Obernier K, Steffen DM, Lim DA, Garcia-Verdugo JM, Alvarez-Buylla A
• Molecular and cellular dynamics of the developing human neocortex.
  Nature 2025 Wang L, Wang C, Moriano JA, Chen S, Zuo G, Cebrián-Silla A, Zhang S, Mukhtar T, Wang S, Song M, de Oliveira LG, Bi Q, Augustin JJ, Ge X, Paredes MF, Huang EJ, Alvarez-Buylla A, Duan X, Li J, …
• A cross-species proteomic map reveals neoteny of human synapse development.
  Nature 2023 Wang L, Pang K, Zhou L, Cebrián-Silla A, González-Granero S, Wang S, Bi Q, White ML, Ho B, Li J, Li T, Perez Y, Huang EJ, Winkler EA, Paredes MF, Kovner R, Sestan N, Pollen AA, Liu P, Li J, Piao X, …
• Ensembles of endothelial and mural cells promote angiogenesis in prenatal human brain.
  Cell 2022 Crouch EE, Bhaduri A, Andrews MG, Cebrian-Silla A, Diafos LN, Birrueta JO, Wedderburn-Pugh K, Valenzuela EJ, Bennett NK, Eze UC, Sandoval-Espinosa C, Chen J, Mora C, Ross JM, Howard CE, Gonzalez-…

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• Comment on "Impact of neurodegenerative diseases on human adult hippocampal neurogenesis".
  Science (New York, N.Y.) 2022 Alvarez-Buylla A, Cebrian-Silla A, Sorrells SF, Nascimento MA, Paredes MF, Garcia-Verdugo JM, Yang Z, Huang EJ
• Nests of dividing neuroblasts sustain interneuron production for the developing human brain.
  Science (New York, N.Y.) 2022 Paredes MF, Mora C, Flores-Ramirez Q, Cebrian-Silla A, Del Dosso A, Larimer P, Chen J, Kang G, Gonzalez Granero S, Garcia E, Chu J, Delgado R, Cotter JA, Tang V, Spatazza J, Obernier K, Ferrer Lozano …
• Single-cell analysis of the ventricular-subventricular zone reveals signatures of dorsal and ventral adult neurogenesis.
  eLife 2021 Cebrian-Silla A, Nascimento MA, Redmond SA, Mansky B, Wu D, Obernier K, Romero Rodriguez R, Gonzalez-Granero S, García-Verdugo JM, Lim DA, Álvarez-Buylla A
• Cellular response to spinal cord injury in regenerative and non-regenerative stages in Xenopus laevis.
  Neural development 2021 Edwards-Faret G, González-Pinto K, Cebrián-Silla A, Peñailillo J, García-Verdugo JM, Larraín J
• Does Adult Neurogenesis Persist in the Human Hippocampus?
  Cell stem cell 2018 Paredes MF, Sorrells SF, Cebrian-Silla A, Sandoval K, Qi D, Kelley KW, James D, Mayer S, Chang J, Auguste KI, Chang EF, Gutierrez Martin AJ, Kriegstein AR, Mathern GW, Oldham MC, Huang EJ, Garcia-…
• Cellular composition and organization of the spinal cord central canal during metamorphosis of the frog Xenopus laevis.
  The Journal of comparative neurology 2018 Edwards-Faret G, Cebrián-Silla A, Méndez-Olivos EE, González-Pinto K, García-Verdugo JM, Larraín J
• Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults.
  Nature 2018 Sorrells SF, Paredes MF, Cebrian-Silla A, Sandoval K, Qi D, Kelley KW, James D, Mayer S, Chang J, Auguste KI, Chang EF, Gutierrez AJ, Kriegstein AR, Mathern GW, Oldham MC, Huang EJ, Garcia-Verdugo JM,…
• Adult Neurogenesis Is Sustained by Symmetric Self-Renewal and Differentiation.
  Cell stem cell 2018 Obernier K, Cebrian-Silla A, Thomson M, Parraguez JI, Anderson R, Guinto C, Rodas Rodriguez J, Garcia-Verdugo JM, Alvarez-Buylla A
• Unique Organization of the Nuclear Envelope in the Post-natal Quiescent Neural Stem Cells.
  Stem cell reports 2017 Cebrián-Silla A, Alfaro-Cervelló C, Herranz-Pérez V, Kaneko N, Park DH, Sawamoto K, Alvarez-Buylla A, Lim DA, García-Verdugo JM
• Netrin-1 receptor antibodies in thymoma-associated neuromyotonia with myasthenia gravis.
  Neurology 2017 Torres-Vega E, Mancheño N, Cebrián-Silla A, Herranz-Pérez V, Chumillas MJ, Moris G, Joubert B, Honnorat J, Sevilla T, Vílchez JJ, Dalmau J, Graus F, García-Verdugo JM, Bataller L
• Annulate Lamellae in a Desmoplastic Small Round Cell Tumor.
  International journal of surgical pathology 2016 Alfaro-Cervelló C, Soriano-Navarro M, Cebrián-Silla A, Forteza-Vila J
• Characterization of multiciliated ependymal cells that emerge in the neurogenic niche of the aged zebrafish brain.
  The Journal of comparative neurology 2016 Ogino T, Sawada M, Takase H, Nakai C, Herranz-Pérez V, Cebrián-Silla A, Kaneko N, García-Verdugo JM, Sawamoto K
• Temporal dynamics of hippocampal neurogenesis in chronic neurodegeneration.
  Brain : a journal of neurology 2014 Gomez-Nicola D, Suzzi S, Vargas-Caballero M, Fransen NL, Al-Malki H, Cebrian-Silla A, Garcia-Verdugo JM, Riecken K, Fehse B, Perry VH
• The adult macaque spinal cord central canal zone contains proliferative cells and closely resembles the human.
  The Journal of comparative neurology 2014 Alfaro-Cervello C, Cebrian-Silla A, Soriano-Navarro M, Garcia-Tarraga P, Matías-Guiu J, Gomez-Pinedo U, Molina Aguilar P, Alvarez-Buylla A, Luquin MR, Garcia-Verdugo JM
• Age-related changes in astrocytic and ependymal cells of the subventricular zone.
  Glia 2014 Capilla-Gonzalez V, Cebrian-Silla A, Guerrero-Cazares H, Garcia-Verdugo JM, Quiñones-Hinojosa A
• Axonal control of the adult neural stem cell niche.
  Cell stem cell 2014 Tong CK, Chen J, Cebrián-Silla A, Mirzadeh Z, Obernier K, Guinto CD, Tecott LH, García-Verdugo JM, Kriegstein A, Alvarez-Buylla A
• Axons take a dive: Specialized contacts of serotonergic axons with cells in the walls of the lateral ventricles in mice and humans.
  Neurogenesis (Austin, Tex.) 2014 Tong CK, Cebrián-Silla A, Paredes MF, Huang EJ, García-Verdugo JM, Alvarez-Buylla A
• The adult spinal cord harbors a population of GFAP-positive progenitors with limited self-renewal potential.
  Glia 2013 Fiorelli R, Cebrian-Silla A, Garcia-Verdugo JM, Raineteau O
• The generation of oligodendroglial cells is preserved in the rostral migratory stream during aging.
  Frontiers in cellular neuroscience 2013 Capilla-Gonzalez V, Cebrian-Silla A, Guerrero-Cazares H, Garcia-Verdugo JM, Quiñones-Hinojosa A
• Adult neural stem cells from the subventricular zone: a review of the neurosphere assay.
  Anatomical record (Hoboken, N.J. : 2007) 2013 Gil-Perotín S, Duran-Moreno M, Cebrián-Silla A, Ramírez M, García-Belda P, García-Verdugo JM
• Vascular-derived TGF-β increases in the stem cell niche and perturbs neurogenesis during aging and following irradiation in the adult mouse brain.
  EMBO molecular medicine 2013 Pineda JR, Daynac M, Chicheportiche A, Cebrian-Silla A, Sii Felice K, Garcia-Verdugo JM, Boussin FD, Mouthon MA
• Subventricular zone neural progenitors protect striatal neurons from glutamatergic excitotoxicity.
  Brain : a journal of neurology 2012 Butti E, Bacigaluppi M, Rossi S, Cambiaghi M, Bari M, Cebrian Silla A, Brambilla E, Musella A, De Ceglia R, Teneud L, De Chiara V, D'Adamo P, Garcia-Verdugo JM, Comi G, Muzio L, Quattrini A, Leocani L…
• GFP immunogold staining, from light to electron microscopy, in mammalian cells.
  Micron (Oxford, England : 1993) 2011 Sirerol-Piquer MS, Cebrián-Silla A, Alfaro-Cervelló C, Gomez-Pinedo U, Soriano-Navarro M, Verdugo JM