Anu Ramachandran, MD, MPH
Assistant Professor
Emergency Medicine
School of Medicine

Publications (8)

Top publication keywords:
Acute Kidney InjuryAcetaminophenLiver Failure, AcuteCytochrome P-450 CYP2E1AntidotesChemical and Drug Induced Liver InjuryAcetylcysteineLiberiaAnti-Bacterial AgentsAnti-Infective AgentsHospitals, PublicHepatocytesAnalgesics, Non-NarcoticEmergency Medical ServicesProtective Agents

• Clinically relevant therapeutic approaches against acetaminophen hepatotoxicity and acute liver failure.
  Biochemical pharmacology 2024 Ramachandran A, Akakpo JY, Curry SC, Rumack BH, Jaeschke H
• Lack of mitochondrial Cyp2E1 drives acetaminophen-induced ER stress-mediated apoptosis in mouse and human kidneys: Inhibition by 4-methylpyrazole but not N-acetylcysteine.
  Toxicology 2023 Akakpo JY, Ramachandran A, Rumack BH, Wallace DP, Jaeschke H
• Implementation and outcomes of a comprehensive emergency care curriculum at a low-resource referral hospital in Liberia: A novel approach to application of the WHO Basic Emergency Care toolkit.
  PloS one 2023 Epps L, Ramachandran A, Yi S, Mayah A, Burkholder T, Jaung M, Haider A, Wesseh P, Shakpeh J, Bills C, Enriquez K
• Emergency department antimicrobial use in a low-resource setting: results from a retrospective observational study at a referral hospital in Liberia.
  BMJ open 2022 Yi S, Ramachandran A, Epps L, Mayah A, Burkholder TW, Jaung MS, Haider A, Whesseh P, Shakpeh J, Enriquez K, Bills C
• Comparing N-acetylcysteine and 4-methylpyrazole as antidotes for acetaminophen overdose.
  Archives of toxicology 2022 Akakpo JY, Ramachandran A, Curry SC, Rumack BH, Jaeschke H
• Performance of Abbott ID-Now rapid nucleic amplification test for laboratory identification of COVID-19 in asymptomatic emergency department patients.
  Journal of the American College of Emergency Physicians open 2021 Ramachandran A, Noble J, Deucher A, Miller S, Tang PW, Wang RC
• Delayed administration of N-acetylcysteine blunts recovery after an acetaminophen overdose unlike 4-methylpyrazole.
  Archives of toxicology 2021 Akakpo JY, Jaeschke MW, Ramachandran A, Curry SC, Rumack BH, Jaeschke H
• 4-methylpyrazole protects against acetaminophen-induced acute kidney injury.
  Toxicology and applied pharmacology 2020 Akakpo JY, Ramachandran A, Orhan H, Curry SC, Rumack BH, Jaeschke H