Annette Molinaro, PhD
Professor
Neurological Surgery
School of Medicine
annette.molinaro@ucsf.edu 415-476-1640
Dr. Molinaro is a principal investigator in the Brain Tumor Research Center at UCSF and the Co-Director of the Clinical and Biostatistics Core for the newly funded UCSF Brain SPORE as well as the Co-Director of the Biospecimen and Biostatistics Core for the newly funded UCSF Brain P01.
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Dr. Molinaro’s research interests are primarily focused on statistical genetics and computational biology, including prediction, survival analysis and classification with additional curiosities in cancer epidemiology and in the estimation of absolute risk in stratified case-cohort studies. Her research has pertained to predicting clinical outcomes with high-dimensional explanatory variables, such as SNP and methylation arrays, and large-scale epidemiology studies. This has included an adaptation to Classification and Regression Trees (CART) for survival outcomes, the introduction of partDSA, a novel data-adaptive algorithm that builds Boolean combinations of explanatory variables, and a non-parametric method for point estimation based on a stratified case-cohort study design. Dr. Molinaro was recently awarded an R01 by the NCI to expand partDSA for building risk models accommodating various study designs and competing risks. In addition, she has worked with collaborators at the National Cancer Institute (NCI) on comparing cross-validation approaches to validating predictors in small sample sizes and the power of data mining methods for detecting genetic associations and interactions.
Awards
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- Diane D. Ralston Clinical and Basic Neuroscience Teaching Award, UCSF, 2013
- Teacher of the Year Award, Yale University School of Public Health, 2008
- Elected as a Member, International Statistical Institute, 2006
- Chin Long Chiang Biostatistics Student of the Year, University of California, Berkeley, 2004
- Evelyn Fix Prize, University of California, Berkeley, 2004
Websites
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- partDSA: Partitioning Using Deletion, Substitution, and Addition Moves (cran.r-project.org)
Grants and Projects
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Publications (244)
Top publication keywords:
OligodendrogliomaBrain Stem NeoplasmsCarcinoma, Basal CellSunbathingAstrocytomaBrain NeoplasmsGlioblastomaBiomarkers, TumorRenal ColicIsocitrate DehydrogenaseGoiter, NodularPrognosisDNA MethylationEpistasis, GeneticGlioma
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A partitioning deletion/substitution/addition algorithm for creating survival risk groups.
Biometrics 2012 Lostritto K, Strawderman RL, Molinaro AM -
Power of data mining methods to detect genetic associations and interactions.
Human heredity 2011 Molinaro AM, Carriero N, Bjornson R, Hartge P, Rothman N, Chatterjee N -
Optimal tumor sampling for immunostaining of biomarkers in breast carcinoma.
Breast cancer research : BCR 2011 Tolles J, Bai Y, Baquero M, Harris LN, Rimm DL, Molinaro AM -
Quantitative assessment shows loss of antigenic epitopes as a function of pre-analytic variables.
Laboratory investigation; a journal of technical methods and pathology 2011 Bai Y, Tolles J, Cheng H, Siddiqui S, Gopinath A, Pectasides E, Camp RL, Rimm DL, Molinaro AM -
Methylated DNA immunoprecipitation genome-wide analysis.
Methods in molecular biology (Clifton, N.J.) 2011 Pelizzola M, Molinaro A -
partDSA: deletion/substitution/addition algorithm for partitioning the covariate space in prediction.
Bioinformatics (Oxford, England) 2010 Molinaro AM, Lostritto K, van der Laan M -
MEDME: an experimental and analytical methodology for the estimation of DNA methylation levels based on microarray derived MeDIP-enrichment.
Genome research 2008 Pelizzola M, Koga Y, Urban AE, Krauthammer M, Weissman S, Halaban R, Molinaro AM -
Prediction error estimation: a comparison of resampling methods.
Bioinformatics (Oxford, England) 2005 Molinaro AM, Simon R, Pfeiffer RM
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Genetic predisposition to altered blood cell homeostasis is associated with glioma risk and survival.
Nature communications 2025 Kachuri L, Guerra GA, Nakase T, Wendt GA, Hansen HM, Molinaro AM, Bracci P, McCoy L, Rice T, Wiencke JK, Eckel-Passow JE, Jenkins RB, Wrensch M, Francis SS -
A phase I study of convection-enhanced delivery (CED) of liposomal-irinotecan using real-time magnetic resonance imaging in patients with recurrent high-grade glioma.
Journal of neuro-oncology 2025 Narsinh KH, Kumar K, Bankiewicz K, Martin AJ, Berger M, Clarke J, Taylor J, Bush NAO, Molinaro AM, Aghi M, Butowski N -
Functional germline variants in DNA damage repair pathways are associated with altered survival in adults with glioma treated with temozolomide.
Neuro-oncology 2025 Guerra G, Wendt G, McCoy L, Hansen HM, Kachuri L, Molinaro AM, Rice T, Guan V, Capistrano L, Hsieh A, Kalsi V, Sallee J, Taylor JW, Clarke JL, Almaraz ER, Wiencke JK, Eckel-Passow JE, Jenkins RB, … -
Practical and statistical aspects of subgroup analyses in surgical neuro-oncology: A comprehensive review from the PIONEER Consortium.
Neuro-oncology 2024 Gerritsen JKW, Karschnia P, Young JS, van den Bent MJ, Chang SM, Smith TR, Nahed BV, Rincon-Torroella J, Bettegowda C, Sanai N, Krieg SM, Maruyama T, Schucht P, Broekman MLD, Tonn JC, Wen PY, De … -
Longitudinal multimodal profiling of IDH-wildtype glioblastoma reveals the molecular evolution and cellular phenotypes underlying prognostically different treatment responses.
Neuro-oncology 2024 Lucas CG, Al-Adli NN, Young JS, Gupta R, Morshed RA, Wu J, Ravindranathan A, Shai A, Oberheim Bush NA, Taylor JW, de Groot J, Villanueva-Meyer JE, Pekmezci M, Perry A, Bollen AW, Theodosopoulos PV, … -
Methylation cytometric pretreatment blood immune profiles with tumor mutation burden as prognostic indicators for survival outcomes in head and neck cancer patients on anti-PD-1 therapy.
NPJ precision oncology 2024 Zhang Z, Sehgal K, Shirai K, Butler RA, Wiencke JK, Koestler DC, Ramush G, Lee MK, Molinaro AM, Stolrow HG, Birnbaum A, Salas LA, Haddad RI, Kelsey KT, Christensen BC -
Construction and performance of a clinical prediction rule for ureteral stone without the use of race or ethnicity: A new STONE score.
Journal of the American College of Emergency Physicians open 2024 Moore CL, Gross CP, Hart L, Molinaro AM, Rhodes D, Singh D, Baloescu C -
Development and validation of a clinical risk model for postoperative outcome in newly diagnosed glioblastoma: a report of the RANO resect group.
Neuro-oncology 2024 Karschnia P, Young JS, Youssef GC, Dono A, Häni L, Sciortino T, Bruno F, Juenger ST, Teske N, Dietrich J, Weller M, Vogelbaum MA, van den Bent M, Beck J, Thon N, Gerritsen JKW, Hervey-Jumper S, Cahill… -
Enhancing neuro-oncology care through equity-driven applications of artificial intelligence.
Neuro-oncology 2024 Mehari M, Sibih Y, Dada A, Chang SM, Wen PY, Molinaro AM, Chukwueke UN, Budhu JA, Jackson S, McFaline-Figueroa JR, Porter A, Hervey-Jumper SL -
Glioma immune microenvironment composition calculator (GIMiCC): a method of estimating the proportions of eighteen cell types from DNA methylation microarray data.
Acta neuropathologica communications 2024 Pike SC, Wiencke JK, Zhang Z, Molinaro AM, Hansen HM, Koestler DC, Christensen BC, Kelsey KT, Salas LA -
Association of immunoglobulin E levels with glioma risk and survival.
Journal of the National Cancer Institute 2024 Guerra G, Nakase T, Kachuri L, McCoy L, Hansen HM, Rice T, Wiemels JL, Wiencke JK, Molinaro AM, Wrensch M, Francis SS -
Functional germline variants in DNA damage repair pathways are associated with altered survival in adults with glioma treated with temozolomide.
medRxiv : the preprint server for health sciences 2024 Guerra G, Wendt G, McCoy L, Hansen HM, Kachuri L, Molinaro AM, Rice T, Guan V, Capistrano L, Hsieh A, Kalsi V, Sallee J, Taylor JW, Clarke JL, Rodriguez Almaraz E, Wiencke JK, Eckel-Passow JE, Jenkins… -
Association of immunoglobulin E levels with glioma risk and survival.
medRxiv : the preprint server for health sciences 2024 Guerra G, Nakase T, Kachuri L, McCoy L, Hansen HM, Rice T, Wiemels JL, Wiencke JK, Molinaro AM, Wrensch M, Francis SS -
Improving glioma drug delivery: A multifaceted approach for glioma drug development.
Pharmacological research 2024 Yonk MG, Lim MA, Thompson CM, Tora MS, Lakhina Y, Du Y, Hoang KB, Molinaro AM, Boulis NM, Hassaneen W, Lei K -
Oligodendroglioma patient survival is associated with circulating B-cells and age.
Neuro-oncology advances 2024 Taylor JW, Warrier G, Hansen HM, McCoy L, Rice T, Guerra G, Francis SS, Clarke JL, Bracci PM, Hadad S, Kelsey KT, Wrensch M, Molinaro AM, Wiencke JK -
An assessment of compositional methods for the analysis of DNA methylation-based deconvolution estimates.
Epigenomics 2024 Alsup A, Nissen E, Salas LA, Molinaro AM, Reiner A, Liu S, Madsen TE, Liu L, Auer PL, Christensen BC, Wiencke JK, Kelsey KT, Koestler DC -
Improving the Generalizability of Deep Learning for T2-Lesion Segmentation of Gliomas in the Post-Treatment Setting.
Bioengineering (Basel, Switzerland) 2024 Ellison J, Caliva F, Damasceno P, Luks TL, LaFontaine M, Cluceru J, Kemisetti A, Li Y, Molinaro AM, Pedoia V, Villanueva-Meyer JE, Lupo JM -
Rational combination platform trial design for children and young adults with diffuse midline glioma: A report from PNOC.
Neuro-oncology 2024 Mueller S, Kline C, Franson A, van der Lugt J, Prados M, Waszak SM, Plasschaert SLA, Molinaro AM, Koschmann C, Nazarian J -
RNA aggregates harness the danger response for potent cancer immunotherapy.
Cell 2024 Mendez-Gomez HR, DeVries A, Castillo P, von Roemeling C, Qdaisat S, Stover BD, Xie C, Weidert F, Zhao C, Moor R, Liu R, Soni D, Ogando-Rivas E, Chardon-Robles J, McGuiness J, Zhang D, Chung MC, … -
Comparison of Volumetric and 2D Measurements and Longitudinal Trajectories in the Response Assessment of BRAF V600E-Mutant Pediatric Gliomas in the Pacific Pediatric Neuro-Oncology Consortium Clinical Trial.
AJNR. American journal of neuroradiology 2024 Ramakrishnan D, Brüningk SC, von Reppert M, Memon F, Maleki N, Aneja S, Kazerooni AF, Nabavizadeh A, Lin M, Bousabarah K, Molinaro A, Nicolaides T, Prados M, Mueller S, Aboian MS -
Associations between recurrence patterns and outcome in glioblastoma patients undergoing re-resection: A complementary report of the RANO resect group.
Neuro-oncology 2024 Karschnia P, Dono A, Young JS, Juenger ST, Teske N, Häni L, Sciortino T, Mau CY, Bruno F, Nunez L, Morshed RA, Haddad AF, Weller M, van den Bent M, Thon N, Beck J, Hervey-Jumper S, Molinaro AM, Tandon… -
Use of External Control Cohorts in Pediatric Brain Tumor Clinical Trials.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2024 Margol AS, Molinaro AM, Onar-Thomas A, Resnick A, Hanson D, Kieran M, Mishra-Kalyani P, Rivera D, Barone A, Arons D, Meehan C, Prados M -
A combinatory vaccine with IMA950 plus varlilumab promotes effector memory T-cell differentiation in the peripheral blood of patients with low-grade gliomas.
Neuro-oncology 2024 Saijo A, Ogino H, Butowski NA, Tedesco MR, Gibson D, Watchmaker PB, Okada K, Wang AS, Shai A, Salazar AM, Molinaro AM, Rabbitt JE, Shahin M, Perry A, Clarke JL, Taylor JW, Daras M, Oberheim Bush NA, … -
Matched analysis of detailed peripheral blood and tumor immune microenvironment profiles in bladder cancer.
Epigenomics 2024 Chen JQ, Salas LA, Wiencke JK, Koestler DC, Molinaro AM, Andrew AS, Seigne JD, Karagas MR, Kelsey KT, Christensen BC -
Surgical management and outcome of newly diagnosed glioblastoma without contrast enhancement (low-grade appearance): a report of the RANO resect group.
Neuro-oncology 2024 Karschnia P, Dietrich J, Bruno F, Dono A, Juenger ST, Teske N, Young JS, Sciortino T, Häni L, van den Bent M, Weller M, Vogelbaum MA, Morshed RA, Haddad AF, Molinaro AM, Tandon N, Beck J, Schnell O, … -
Enrichment of a neutrophil-like monocyte transcriptional state in glioblastoma myeloid suppressor cells.
Research square 2023 Wiencke JK, Nissen E, Koestler DC, Tamaki SJ, Tamaki CM, Hansen HM, Warrier G, Hadad S, McCoy L, Rice T, Clarke J, Taylor JW, Salas LA, Christensen BC, Kelsey KT, Butler R, Molinaro AM -
"De novo replication repair deficient glioblastoma, IDH-wildtype" is a distinct glioblastoma subtype in adults that may benefit from immune checkpoint blockade.
Acta neuropathologica 2023 Hadad S, Gupta R, Oberheim Bush NA, Taylor JW, Villanueva-Meyer JE, Young JS, Wu J, Ravindranathan A, Zhang Y, Warrier G, McCoy L, Shai A, Pekmezci M, Perry A, Bollen AW, Phillips JJ, Braunstein SE, … -
Everolimus for Children With Recurrent or Progressive Low-Grade Glioma: Results From the Phase II PNOC001 Trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2023 Haas-Kogan DA, Aboian MS, Minturn JE, Leary SES, Abdelbaki MS, Goldman S, Elster JD, Kraya A, Lueder MR, Ramakrishnan D, von Reppert M, Liu KX, Rokita JL, Resnick AC, Solomon DA, Phillips JJ, Prados M… -
PNOC015: Repeated convection-enhanced delivery of MTX110 (aqueous panobinostat) in children with newly diagnosed diffuse intrinsic pontine glioma.
Neuro-oncology 2023 Mueller S, Kline C, Stoller S, Lundy S, Christopher L, Reddy AT, Banerjee A, Cooney TM, Raber S, Hoffman C, Luks T, Wembacher-Schroeder E, Lummel N, Zhang Y, Bonner ER, Nazarian J, Molinaro AM, Prados… -
Genetic predisposition to altered blood cell homeostasis is associated with glioma risk and survival.
medRxiv : the preprint server for health sciences 2023 Kachuri L, Guerra GA, Wendt GA, Hansen HM, Molinaro AM, Bracci P, McCoy L, Rice T, Wiencke JK, Eckel-Passow JE, Jenkins RB, Wrensch M, Francis SS -
Genome-Scale Methylation Analysis Identifies Immune Profiles and Age Acceleration Associations with Bladder Cancer Outcomes.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2023 Chen JQ, Salas LA, Wiencke JK, Koestler DC, Molinaro AM, Andrew AS, Seigne JD, Karagas MR, Kelsey KT, Christensen BC -
RANO 2.0: Update to the Response Assessment in Neuro-Oncology Criteria for High- and Low-Grade Gliomas in Adults.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2023 Wen PY, van den Bent M, Youssef G, Cloughesy TF, Ellingson BM, Weller M, Galanis E, Barboriak DP, de Groot J, Gilbert MR, Huang R, Lassman AB, Mehta M, Molinaro AM, Preusser M, Rahman R, Shankar LK, … -
Prognostic evaluation of re-resection for recurrent glioblastoma using the novel RANO classification for extent of resection: A report of the RANO resect group.
Neuro-oncology 2023 Karschnia P, Dono A, Young JS, Juenger ST, Teske N, Häni L, Sciortino T, Mau CY, Bruno F, Nunez L, Morshed RA, Haddad AF, Weller M, van den Bent M, Beck J, Hervey-Jumper S, Molinaro AM, Tandon N, Rudà… -
Multi-parametric hyperpolarized 13C/1H imaging reveals Warburg-related metabolic dysfunction and associated regional heterogeneity in high-grade human gliomas.
NeuroImage. Clinical 2023 Autry AW, Vaziri S, LaFontaine M, Gordon JW, Chen HY, Kim Y, Villanueva-Meyer JE, Molinaro A, Clarke JL, Oberheim Bush NA, Xu D, Lupo JM, Larson PEZ, Vigneron DB, Chang SM, Li Y -
Calculating detection limits and uncertainty of reference-based deconvolution of whole-blood DNA methylation data.
Epigenomics 2023 Bell-Glenn S, Salas LA, Molinaro AM, Butler RA, Christensen BC, Kelsey KT, Wiencke JK, Koestler DC -
Hierarchical deconvolution for extensive cell type resolution in the human brain using DNA methylation.
Frontiers in neuroscience 2023 Zhang Z, Wiencke JK, Kelsey KT, Koestler DC, Molinaro AM, Pike SC, Karra P, Christensen BC, Salas LA -
Antibodies to varicella-zoster virus and three other herpesviruses and survival in adults with glioma.
Neuro-oncology 2023 Guerra G, McCoy L, Hansen HM, Rice T, Molinaro AM, Wiemels JL, Wiencke JK, Wrensch M, Francis SS -
Prognostic validation of a new classification system for extent of resection in glioblastoma: A report of the RANO resect group.
Neuro-oncology 2023 Karschnia P, Young JS, Dono A, Häni L, Sciortino T, Bruno F, Juenger ST, Teske N, Morshed RA, Haddad AF, Zhang Y, Stoecklein S, Weller M, Vogelbaum MA, Beck J, Tandon N, Hervey-Jumper S, Molinaro AM, … -
Glioblastoma remodelling of human neural circuits decreases survival.
Nature 2023 Krishna S, Choudhury A, Keough MB, Seo K, Ni L, Kakaizada S, Lee A, Aabedi A, Popova G, Lipkin B, Cao C, Nava Gonzales C, Sudharshan R, Egladyous A, Almeida N, Zhang Y, Molinaro AM, Venkatesh HS, … -
Assessment of immune cell profiles among post-menopausal women in the Women's Health Initiative using DNA methylation-based methods.
Clinical epigenetics 2023 Nissen E, Reiner A, Liu S, Wallace RB, Molinaro AM, Salas LA, Christensen BC, Wiencke JK, Koestler DC, Kelsey KT -
A Systematic Review Comparing Focused Ultrasound Surgery With Radiosurgery for Essential Tremor.
Neurosurgery 2023 Kondapavulur S, Silva AB, Molinaro AM, Wang DD -
Identification of risk factors associated with leptomeningeal disease after resection of brain metastases.
Journal of neurosurgery 2023 Morshed RA, Saggi S, Cummins DD, Molinaro AM, Young JS, Viner JA, Villanueva-Meyer JE, Goldschmidt E, Boreta L, Braunstein SE, Chang EF, McDermott MW, Berger MS, Theodosopoulos PV, Hervey-Jumper SL, … -
Interactive Effects of Molecular, Therapeutic, and Patient Factors on Outcome of Diffuse Low-Grade Glioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2023 Hervey-Jumper SL, Zhang Y, Phillips JJ, Morshed RA, Young JS, McCoy L, Lafontaine M, Luks T, Ammanuel S, Kakaizada S, Egladyous A, Gogos A, Villanueva-Meyer J, Shai A, Warrier G, Rice T, Crane J, … -
Comparative analysis of the DNA methylation landscape in CD4, CD8, and B memory lineages.
Clinical epigenetics 2022 Zhang Z, Butler R, Koestler DC, Bell-Glenn S, Warrier G, Molinaro AM, Christensen BC, Wiencke JK, Kelsey KT, Salas LA -
Evaluation of cross-platform compatibility of a DNA methylation-based glucocorticoid response biomarker.
Clinical epigenetics 2022 Tang E, Wiencke JK, Warrier G, Hansen H, McCoy L, Rice T, Bracci PM, Wrensch M, Taylor JW, Clarke JL, Koestler DC, Salas LA, Christensen BC, Kelsey KT, Molinaro AM -
Prospective genomically guided identification of "early/evolving" and "undersampled" IDH-wildtype glioblastoma leads to improved clinical outcomes.
Neuro-oncology 2022 Zhang Y, Lucas CG, Young JS, Morshed RA, McCoy L, Oberheim Bush NA, Taylor JW, Daras M, Butowski NA, Villanueva-Meyer JE, Cha S, Wrensch M, Wiencke JK, Lee JC, Pekmezci M, Phillips JJ, Perry A, Bollen… -
TERT promotor status does not add prognostic information in IDH-wildtype glioblastomas fulfilling other diagnostic WHO criteria: A report of the RANO resect group.
Neuro-oncology advances 2022 Karschnia P, Young JS, Dono A, Häni L, Juenger ST, Sciortino T, Bruno F, Teske N, Morshed RA, Haddad AF, Zhang Y, Stoecklein S, Vogelbaum MA, Beck J, Tandon N, Hervey-Jumper S, Molinaro AM, Rudà R, … -
DNA methylation as a pharmacodynamic marker of glucocorticoid response and glioma survival.
Nature communications 2022 Wiencke JK, Molinaro AM, Warrier G, Rice T, Clarke J, Taylor JW, Wrensch M, Hansen H, McCoy L, Tang E, Tamaki SJ, Tamaki CM, Nissen E, Bracci P, Salas LA, Koestler DC, Christensen BC, Zhang Z, Kelsey … -
GABP couples oncogene signaling to telomere regulation in TERT promoter mutant cancer.
Cell reports 2022 McKinney AM, Mathur R, Stevers NO, Molinaro AM, Chang SM, Phillips JJ, Costello JF -
Upfront Biology-Guided Therapy in Diffuse Intrinsic Pontine Glioma: Therapeutic, Molecular, and Biomarker Outcomes from PNOC003.
Clinical cancer research : an official journal of the American Association for Cancer Research 2022 Kline C, Jain P, Kilburn L, Bonner ER, Gupta N, Crawford JR, Banerjee A, Packer RJ, Villanueva-Meyer J, Luks T, Zhang Y, Kambhampati M, Zhang J, Yadavilli S, Zhang B, Gaonkar KS, Rokita JL, Kraya A, … -
Functional network alterations in young brain tumor patients with radiotherapy-induced memory impairments and vascular injury.
Frontiers in neurology 2022 Morrison MA, Walter S, Mueller S, Felton E, Jakary A, Stoller S, Molinaro AM, Braunstein SE, Hess CP, Lupo JM -
PI3K/AKT/mTOR signaling pathway activity in IDH-mutant diffuse glioma and clinical implications.
Neuro-oncology 2022 Mohamed E, Kumar A, Zhang Y, Wang AS, Chen K, Lim Y, Shai A, Taylor JW, Clarke J, Hilz S, Berger MS, Solomon DA, Costello JF, Molinaro AM, Phillips JJ -
Prognostic risk stratification of gliomas using deep learning in digital pathology images.
Neuro-oncology advances 2022 Chunduru P, Phillips JJ, Molinaro AM -
CXCL14 Promotes a Robust Brain Tumor-Associated Immune Response in Glioma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2022 Kumar A, Mohamed E, Tong S, Chen K, Mukherjee J, Lim Y, Wong CM, Boosalis Z, Shai A, Pieper RO, Gupta N, Perry A, Bollen AW, Molinaro AM, Solomon DA, Shieh JTC, Phillips JJ -
Pre-surgery immune profiles of adult glioma patients.
Journal of neuro-oncology 2022 Bracci PM, Rice T, Hansen HM, Francis SS, Lee S, McCoy LS, Shrestha PP, Warrier G, Clarke JL, Molinaro AM, Taylor JW, Wiencke JK, Wrensch MR -
Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma.
The Journal of clinical investigation 2022 Mueller S, Taitt JM, Villanueva-Meyer JE, Bonner ER, Nejo T, Lulla RR, Goldman S, Banerjee A, Chi SN, Whipple NS, Crawford JR, Gauvain K, Nazemi KJ, Watchmaker PB, Almeida ND, Okada K, Salazar AM, … -
The immunogenetics of viral antigen response is associated with subtype-specific glioma risk and survival.
American journal of human genetics 2022 Guerra G, Kachuri L, Wendt G, Hansen HM, Mack SJ, Molinaro AM, Rice T, Bracci P, Wiencke JK, Kasahara N, Eckel-Passow JE, Jenkins RB, Wrensch M, Francis SS -
Improving the noninvasive classification of glioma genetic subtype with deep learning and diffusion-weighted imaging.
Neuro-oncology 2022 Cluceru J, Interian Y, Phillips JJ, Molinaro AM, Luks TL, Alcaide-Leon P, Olson MP, Nair D, LaFontaine M, Shai A, Chunduru P, Pedoia V, Villanueva-Meyer JE, Chang SM, Lupo JM -
Regression trees and ensembles for cumulative incidence functions.
The international journal of biostatistics 2022 Cho Y, Molinaro AM, Hu C, Strawderman RL -
Socioeconomic factors associated with pediatric moyamoya disease hospitalizations: a nationwide cross-sectional study.
Journal of neurosurgery. Pediatrics 2022 Raygor KP, Phelps RRL, Rutledge C, Raper DMS, Molinaro A, Fox CK, Gupta N, Abla AA -
Interactions of Age and Blood Immune Factors and Noninvasive Prediction of Glioma Survival.
Journal of the National Cancer Institute 2022 Molinaro AM, Wiencke JK, Warrier G, Koestler DC, Chunduru P, Lee JY, Hansen HM, Lee S, Anguiano J, Rice T, Bracci PM, McCoy L, Salas LA, Christensen BC, Wrensch M, Kelsey KT, Taylor JW, Clarke JL -
A core of differentially methylated CpG loci in gMDSCs isolated from neonatal and adult sources.
Clinical epigenetics 2022 Berglund-Brown I, Nissen E, Koestler DC, Butler RA, Eliot MN, Padbury JF, Salas LA, Molinaro AM, Christensen BC, Wiencke JK, Kelsey KT -
Categorizing continuous biomarkers: More cons than pros.
Neuro-oncology practice 2022 Zhang Y, Molinaro AM -
Enhanced cell deconvolution of peripheral blood using DNA methylation for high-resolution immune profiling.
Nature communications 2022 Salas LA, Zhang Z, Koestler DC, Butler RA, Hansen HM, Molinaro AM, Wiencke JK, Kelsey KT, Christensen BC -
External controls to improve on glioblastoma clinical trials.
Neuro-oncology 2022 Molinaro AM -
Randomized trial of neoadjuvant vaccination with tumor-cell lysate induces T cell response in low-grade gliomas.
The Journal of clinical investigation 2022 Ogino H, Taylor JW, Nejo T, Gibson D, Watchmaker PB, Okada K, Saijo A, Tedesco MR, Shai A, Wong CM, Rabbitt JE, Olin MR, Moertel CL, Nishioka Y, Salazar AM, Molinaro AM, Phillips JJ, Butowski NA, … -
Immune profiles and DNA methylation alterations related with non-muscle-invasive bladder cancer outcomes.
Clinical epigenetics 2022 Chen JQ, Salas LA, Wiencke JK, Koestler DC, Molinaro AM, Andrew AS, Seigne JD, Karagas MR, Kelsey KT, Christensen BC -
Association of Neurological Impairment on the Relative Benefit of Maximal Extent of Resection in Chemoradiation-Treated Newly Diagnosed Isocitrate Dehydrogenase Wild-Type Glioblastoma.
Neurosurgery 2022 Aabedi AA, Young JS, Zhang Y, Ammanuel S, Morshed RA, Dalle Ore C, Brown D, Phillips JJ, Oberheim Bush NA, Taylor JW, Butowski N, Clarke J, Chang SM, Aghi M, Molinaro AM, Berger MS, Hervey-Jumper SL -
Reducing complication rates for repeat craniotomies in glioma patients: a single-surgeon experience and comparison with the literature.
Acta neurochirurgica 2021 Morshed RA, Young JS, Gogos AJ, Haddad AF, McMahon JT, Molinaro AM, Sudhakar V, Al-Adli N, Hervey-Jumper SL, Berger MS -
Skin disease in goats (Capra aegagrus hircus): a retrospective study of 358 cases at a university veterinary teaching hospital (1988-2020).
Veterinary dermatology 2021 White SD, Affolter VK, Molinaro AM, Depenbrock SM, Chigerwe M, Heller MC, Rowe JD -
Temozolomide-induced hypermutation is associated with distant recurrence and reduced survival after high-grade transformation of low-grade IDH-mutant gliomas.
Neuro-oncology 2021 Yu Y, Villanueva-Meyer J, Grimmer MR, Hilz S, Solomon DA, Choi S, Wahl M, Mazor T, Hong C, Shai A, Phillips JJ, Wainer BH, McDermott M, Haas-Kogan D, Taylor JW, Butowski N, Clarke JL, Berger MS, … -
Correlation of natural language assessment results with health-related quality of life in adult glioma patients.
Journal of neurosurgery 2021 Ammanuel SG, Almeida NC, Kurteff G, Kakaizada S, Molinaro AM, Berger MS, Chang EF, Hervey-Jumper SL -
A single institution retrospective analysis on survival based on treatment paradigms for patients with anaplastic oligodendroglioma.
Journal of neuro-oncology 2021 Bush NAO, Young JS, Zhang Y, Dalle Ore CL, Molinaro AM, Taylor J, Clarke J, Prados M, Braunstein SE, Raleigh DR, Chang SM, Berger MS, Butowski NA -
Detection of glioma infiltration at the tumor margin using quantitative stimulated Raman scattering histology.
Scientific reports 2021 Pekmezci M, Morshed RA, Chunduru P, Pandian B, Young J, Villanueva-Meyer JE, Tihan T, Sloan EA, Aghi MK, Molinaro AM, Berger MS, Hervey-Jumper SL -
Smoking Is an Independent Risk Factor for 90-Day Readmission and Reoperation Following Posterior Cervical Decompression and Fusion.
Neurosurgery 2021 Badiee RK, Chan AK, Rivera J, Molinaro A, Chou D, Mummaneni PV, Tan LA -
The Relationship Between Stimulation Current and Functional Site Localization During Brain Mapping.
Neurosurgery 2021 Muster RH, Young JS, Woo PYM, Morshed RA, Warrier G, Kakaizada S, Molinaro AM, Berger MS, Hervey-Jumper SL -
Relationship between 7T MR-angiography features of vascular injury and cognitive decline in young brain tumor patients treated with radiation therapy.
Journal of neuro-oncology 2021 Avadiappan S, Morrison MA, Jakary A, Felton E, Stoller S, Hess CP, Molinaro AM, Braunstein SE, Mueller S, Lupo JM -
Identification of a foetal epigenetic compartment in adult human kidney.
Epigenetics 2021 Wiencke JK, Zhang Z, Koestler DC, Salas LA, Molinaro AM, Christensen BC, Kelsey KT -
Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma.
The Journal of clinical investigation 2020 Mueller S, Taitt JM, Villanueva-Meyer JE, Bonner ER, Nejo T, Lulla RR, Goldman S, Banerjee A, Chi SN, Whipple NS, Crawford JR, Gauvain K, Nazemi KJ, Watchmaker PB, Almeida ND, Okada K, Salazar AM, … -
Adult diffuse glioma GWAS by molecular subtype identifies variants in D2HGDH and FAM20C.
Neuro-oncology 2020 Eckel-Passow JE, Drucker KL, Kollmeyer TM, Kosel ML, Decker PA, Molinaro AM, Rice T, Praska CE, Clark L, Caron A, Abyzov A, Batzler A, Song JS, Pekmezci M, Hansen HM, McCoy LS, Bracci PM, Wiemels J, … -
MGMT promoter methylation level in newly diagnosed low-grade glioma is a predictor of hypermutation at recurrence.
Neuro-oncology 2020 Mathur R, Zhang Y, Grimmer MR, Hong C, Zhang M, Bollam S, Petrecca K, Clarke J, Berger MS, Phillips JJ, Oberheim-Bush NA, Molinaro AM, Chang SM, Costello JF -
Randomized Phase II and Biomarker Study of Pembrolizumab plus Bevacizumab versus Pembrolizumab Alone for Patients with Recurrent Glioblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2020 Nayak L, Molinaro AM, Peters K, Clarke JL, Jordan JT, de Groot J, Nghiemphu L, Kaley T, Colman H, McCluskey C, Gaffey S, Smith TR, Cote DJ, Severgnini M, Yearley JH, Zhao Q, Blumenschein WM, Duda DG, … -
Clinical, radiologic, and genetic characteristics of histone H3 K27M-mutant diffuse midline gliomas in adults.
Neuro-oncology advances 2020 Schulte JD, Buerki RA, Lapointe S, Molinaro AM, Zhang Y, Villanueva-Meyer JE, Perry A, Phillips JJ, Tihan T, Bollen AW, Pekmezci M, Butowski N, Oberheim Bush NA, Taylor JW, Chang SM, Theodosopoulos P,… -
Recurrent tumor and treatment-induced effects have different MR signatures in contrast enhancing and non-enhancing lesions of high-grade gliomas.
Neuro-oncology 2020 Cluceru J, Nelson SJ, Wen Q, Phillips JJ, Shai A, Molinaro AM, Alcaide-Leon P, Olson MP, Nair D, LaFontaine M, Chunduru P, Villanueva-Meyer JE, Cha S, Chang SM, Berger MS, Lupo JM -
Consensus-based perioperative protocols during the COVID-19 pandemic.
Journal of neurosurgery. Spine 2020 Mummaneni PV, Burke JF, Chan AK, Sosa JA, Lobo EP, Mummaneni VP, Antrum S, Berven SH, Conte MS, Doernberg SB, Goldberg AN, Hess CP, Hetts SW, Josephson SA, Kohi MP, Ma CB, Mahadevan VS, Molinaro AM, … -
Rate of radiation-induced microbleed formation on 7T MRI relates to cognitive impairment in young patients treated with radiation therapy for a brain tumor.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2020 Morrison MA, Mueller S, Felton E, Jakary A, Stoller S, Avadiappan S, Yuan J, Molinaro AM, Braunstein S, Banerjee A, Hess CP, Lupo JM -
Phase I study of vemurafenib in children with recurrent or progressive BRAFV600E mutant brain tumors: Pacific Pediatric Neuro-Oncology Consortium study (PNOC-002).
Oncotarget 2020 Nicolaides T, Nazemi KJ, Crawford J, Kilburn L, Minturn J, Gajjar A, Gauvain K, Leary S, Dhall G, Aboian M, Robinson G, Long-Boyle J, Wang H, Molinaro AM, Mueller S, Prados M -
The influence of race and socioeconomic status on therapeutic clinical trial screening and enrollment.
Journal of neuro-oncology 2020 Morshed RA, Reihl SJ, Molinaro AM, Kakaizada S, Young JS, Schulte JD, Butowski N, Taylor J, Bush NA, Aghi MK, Berger MS, Chang S, Clarke J, Hervey-Jumper SL -
The impact of obesity on perioperative complications in patients undergoing anterior lumbar interbody fusion.
Journal of neurosurgery. Spine 2020 Safaee MM, Tenorio A, Osorio JA, Choy W, Amara D, Lai L, Molinaro AM, Zhang Y, Hu SS, Tay B, Burch S, Berven SH, Deviren V, Dhall SS, Chou D, Mummaneni PV, Eichler CM, Ames CP, Clark AJ -
Association of Maximal Extent of Resection of Contrast-Enhanced and Non-Contrast-Enhanced Tumor With Survival Within Molecular Subgroups of Patients With Newly Diagnosed Glioblastoma.
JAMA oncology 2020 Molinaro AM, Hervey-Jumper S, Morshed RA, Young J, Han SJ, Chunduru P, Zhang Y, Phillips JJ, Shai A, Lafontaine M, Crane J, Chandra A, Flanigan P, Jahangiri A, Cioffi G, Ostrom Q, Anderson JE, Badve C… -
Residual Tumor Volume and Location Predict Progression After Primary Subtotal Resection of Sporadic Vestibular Schwannomas: A Retrospective Volumetric Study.
Neurosurgery 2020 Breshears JD, Morshed RA, Molinaro AM, McDermott MW, Cheung SW, Theodosopoulos PV -
Safety of Outpatient Anterior Cervical Discectomy and Fusion: A Systematic Review and Meta-Analysis.
Neurosurgery 2020 Yerneni K, Burke JF, Chunduru P, Molinaro AM, Riew KD, Traynelis VC, Tan LA -
Longitudinal molecular trajectories of diffuse glioma in adults.
Nature 2019 Barthel FP, Johnson KC, Varn FS, Moskalik AD, Tanner G, Kocakavuk E, Anderson KJ, Abiola O, Aldape K, Alfaro KD, Alpar D, Amin SB, Ashley DM, Bandopadhayay P, Barnholtz-Sloan JS, Beroukhim R, Bock C, … -
EGFR amplification status for clinical trial inclusion: where do we draw the line?
Neuro-oncology 2019 Molinaro AM, Phillips JJ -
Preoperative Narcotic Use, Impaired Ambulation Status, and Increased Intraoperative Blood Loss Are Independent Risk Factors for Complications Following Posterior Cervical Laminectomy and Fusion Surgery.
Neurospine 2019 Badiee RK, Chan AK, Rivera J, Molinaro A, Doherty BR, Riew KD, Chou D, Mummaneni PV, Tan LA -
Phase I trial of caudate deep brain stimulation for treatment-resistant tinnitus.
Journal of neurosurgery 2019 Cheung SW, Racine CA, Henderson-Sabes J, Demopoulos C, Molinaro AM, Heath S, Nagarajan SS, Bourne AL, Rietcheck JE, Wang SS, Larson PS -
Genetic interaction analysis of VEGF-A rs3025039 and VEGFR-2 rs2071559 identifies a genetic profile at higher risk to develop nodular goiter.
Journal of endocrinological investigation 2019 Molinaro A, Orlandi P, Niccolai F, Agretti P, De Marco G, Ferrarini E, Di Cosmo C, Vitti P, Piaggi P, Di Desidero T, Bocci G, Tonacchera M -
A historical cohort of temporal lobe surgery for medically refractory epilepsy: a systematic review and meta-analysis to guide future nonrandomized controlled trial studies.
Journal of neurosurgery 2019 Lee AT, Burke JF, Chunduru P, Molinaro AM, Knowlton R, Chang EF -
Genetic and molecular epidemiology of adult diffuse glioma.
Nature reviews. Neurology 2019 Molinaro AM, Taylor JW, Wiencke JK, Wrensch MR -
Factor analysis for survival time prediction with informative censoring and diverse covariates.
Statistics in medicine 2019 McCurdy S, Molinaro A, Pachter L -
An independently validated nomogram for isocitrate dehydrogenase-wild-type glioblastoma patient survival.
Neuro-oncology advances 2019 Gittleman H, Cioffi G, Chunduru P, Molinaro AM, Berger MS, Sloan AE, Barnholtz-Sloan JS -
Reirradiation of recurrent high-grade glioma and development of prognostic scores for progression and survival.
Neuro-oncology practice 2019 Chapman CH, Hara JH, Molinaro AM, Clarke JL, Oberheim Bush NA, Taylor JW, Butowski NA, Chang SM, Fogh SE, Sneed PK, Nakamura JL, Raleigh DR, Braunstein SE -
A pilot precision medicine trial for children with diffuse intrinsic pontine glioma-PNOC003: A report from the Pacific Pediatric Neuro-Oncology Consortium.
International journal of cancer 2019 Mueller S, Jain P, Liang WS, Kilburn L, Kline C, Gupta N, Panditharatna E, Magge SN, Zhang B, Zhu Y, Crawford JR, Banerjee A, Nazemi K, Packer RJ, Petritsch CK, Truffaux N, Roos A, Nasser S, Phillips … -
Using germline variants to estimate glioma and subtype risks.
Neuro-oncology 2019 Eckel-Passow JE, Decker PA, Kosel ML, Kollmeyer TM, Molinaro AM, Rice T, Caron AA, Drucker KL, Praska CE, Pekmezci M, Hansen HM, McCoy LS, Bracci PM, Erickson BJ, Lucchinetti CF, Wiemels JL, Wiencke … -
Longer genotypically-estimated leukocyte telomere length is associated with increased meningioma risk.
Journal of neuro-oncology 2019 Muskens IS, Hansen HM, Smirnov IV, Molinaro AM, Bondy ML, Schildkraut JM, Wrensch M, Wiemels JL, Claus EB -
Risk factors of radiotherapy-induced cerebral microbleeds and serial analysis of their size compared with white matter changes: A 7T MRI study in 113 adult patients with brain tumors.
Journal of magnetic resonance imaging : JMRI 2019 Morrison MA, Hess CP, Clarke JL, Butowski N, Chang SM, Molinaro AM, Lupo JM -
Temporal Dynamics of Pseudoprogression After Gamma Knife Radiosurgery for Vestibular Schwannomas-A Retrospective Volumetric Study.
Neurosurgery 2019 Breshears JD, Chang J, Molinaro AM, Sneed PK, McDermott MW, Tward A, Theodosopoulos PV -
Postoperative Delirium in Glioblastoma Patients: Risk Factors and Prognostic Implications.
Neurosurgery 2018 Flanigan PM, Jahangiri A, Weinstein D, Dayani F, Chandra A, Kanungo I, Choi S, Sankaran S, Molinaro AM, McDermott MW, Berger MS, Aghi MK -
Impact of pretreatment growth on Tumor control for vestibular schwannomas following gamma knife.
The Laryngoscope 2018 Chang J, Breshears JD, Molinaro AM, Sneed PK, McDermott MW, Theodosopoulos PV, Tward AD -
Phase-2 trial of palbociclib in adult patients with recurrent RB1-positive glioblastoma.
Journal of neuro-oncology 2018 Taylor JW, Parikh M, Phillips JJ, James CD, Molinaro AM, Butowski NA, Clarke JL, Oberheim-Bush NA, Chang SM, Berger MS, Prados M -
Relationship of In Vivo MR Parameters to Histopathological and Molecular Characteristics of Newly Diagnosed, Nonenhancing Lower-Grade Gliomas.
Translational oncology 2018 Luks TL, McKnight TR, Jalbert LE, Williams A, Neill E, Lobo KA, Persson AI, Perry A, Phillips JJ, Molinaro AM, Chang SM, Nelson SJ -
Disparities in health care determine prognosis in newly diagnosed glioblastoma.
Neurosurgical focus 2018 Chandra A, Rick JW, Dalle Ore C, Lau D, Nguyen AT, Carrera D, Bonte A, Molinaro AM, Theodosopoulos PV, McDermott MW, Berger MS, Aghi MK -
Developing an Algorithm for Optimizing Care of Elderly Patients With Glioblastoma.
Neurosurgery 2018 Flanigan PM, Jahangiri A, Kuang R, Truong A, Choi S, Chou A, Molinaro AM, McDermott MW, Berger MS, Aghi MK -
Improved Survival with Decreased Wait Time to Surgery in Glioblastoma Patients Presenting with Seizure.
Neurosurgery 2017 Flanigan PM, Jahangiri A, Kuang R, Truong A, Choi S, Chou A, Rick JW, Chang SM, Molinaro AM, McDermott MW, Berger MS, Aghi MK -
Prospective Feasibility Trial for Genomics-Informed Treatment in Recurrent and Progressive Glioblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Byron SA, Tran NL, Halperin RF, Phillips JJ, Kuhn JG, de Groot JF, Colman H, Ligon KL, Wen PY, Cloughesy TF, Mellinghoff IK, Butowski NA, Taylor JW, Clarke JL, Chang SM, Berger MS, Molinaro AM, … -
Germline polymorphisms in myeloid-associated genes are not associated with survival in glioma patients.
Journal of neuro-oncology 2017 Jacobs DI, Liu Y, Gabrusiewicz K, Tsavachidis S, Armstrong GN, Zhou R, Wei J, Ivan C, Calin G, Molinaro AM, Rice T, Bracci PM, Hansen HM, Wiencke JK, Wrensch MR, Heimberger AB, Bondy ML -
Characterization of Metabolic, Diffusion, and Perfusion Properties in GBM: Contrast-Enhancing versus Non-Enhancing Tumor.
Translational oncology 2017 Autry A, Phillips JJ, Maleschlijski S, Roy R, Molinaro AM, Chang SM, Cha S, Lupo JM, Nelson SJ -
Clonal expansion and epigenetic reprogramming following deletion or amplification of mutant IDH1.
Proceedings of the National Academy of Sciences of the United States of America 2017 Mazor T, Chesnelong C, Pankov A, Jalbert LE, Hong C, Hayes J, Smirnov IV, Marshall R, Souza CF, Shen Y, Viswanath P, Noushmehr H, Ronen SM, Jones SJM, Marra MA, Cairncross JG, Perry A, Nelson SJ, … -
Probing the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway in gliomas: A phase 2 study of everolimus for recurrent adult low-grade gliomas.
Cancer 2017 Wahl M, Chang SM, Phillips JJ, Molinaro AM, Costello JF, Mazor T, Alexandrescu S, Lupo JM, Nelson SJ, Berger M, Prados M, Taylor JW, Butowski N, Clarke JL, Haas-Kogan D -
Identifying Voxels at Risk for Progression in Glioblastoma Based on Dosimetry, Physiologic and Metabolic MRI.
Radiation research 2017 Anwar M, Molinaro AM, Morin O, Chang SM, Haas-Kogan DA, Nelson SJ, Lupo JM -
Metabolic Profiling of IDH Mutation and Malignant Progression in Infiltrating Glioma.
Scientific reports 2017 Jalbert LE, Elkhaled A, Phillips JJ, Neill E, Williams A, Crane JC, Olson MP, Molinaro AM, Berger MS, Kurhanewicz J, Ronen SM, Chang SM, Nelson SJ -
Family-centred care for children and young people with cerebral palsy: results from an Italian multicenter observational study.
Child: care, health and development 2017 Molinaro A, Fedrizzi E, Calza S, Pagliano E, Jessica G, Fazzi E, GIPCI Study Group -
Adult infiltrating gliomas with WHO 2016 integrated diagnosis: additional prognostic roles of ATRX and TERT.
Acta neuropathologica 2017 Pekmezci M, Rice T, Molinaro AM, Walsh KM, Decker PA, Hansen H, Sicotte H, Kollmeyer TM, McCoy LS, Sarkar G, Perry A, Giannini C, Tihan T, Berger MS, Wiemels JL, Bracci PM, Eckel-Passow JE, Lachance … -
Association of early changes in 1H MRSI parameters with survival for patients with newly diagnosed glioblastoma receiving a multimodality treatment regimen.
Neuro-oncology 2017 Nelson SJ, Kadambi AK, Park I, Li Y, Crane J, Olson M, Molinaro A, Roy R, Butowski N, Cha S, Chang S -
A phase 1 trial of intravenous liposomal irinotecan in patients with recurrent high-grade glioma.
Cancer chemotherapy and pharmacology 2017 Clarke JL, Molinaro AM, Cabrera JR, DeSilva AA, Rabbitt JE, Prey J, Drummond DC, Kim J, Noble C, Fitzgerald JB, Chang SM, Butowski NA, Taylor JW, Park JW, Prados MD -
Clinical trial endpoints for patients with gliomas.
Neuro-oncology practice 2017 Taylor JW, Molinaro AM, Butowski N, Prados M -
Immunomethylomic approach to explore the blood neutrophil lymphocyte ratio (NLR) in glioma survival.
Clinical epigenetics 2017 Wiencke JK, Koestler DC, Salas LA, Wiemels JL, Roy RP, Hansen HM, Rice T, McCoy LS, Bracci PM, Molinaro AM, Kelsey KT, Wrensch MR, Christensen BC -
Chemotherapy for adult low-grade gliomas: clinical outcomes by molecular subtype in a phase II study of adjuvant temozolomide.
Neuro-oncology 2017 Wahl M, Phillips JJ, Molinaro AM, Lin Y, Perry A, Haas-Kogan DA, Costello JF, Dayal M, Butowski N, Clarke JL, Prados M, Nelson S, Berger MS, Chang SM -
GLUT3 upregulation promotes metabolic reprogramming associated with antiangiogenic therapy resistance.
JCI insight 2017 Kuang R, Jahangiri A, Mascharak S, Nguyen A, Chandra A, Flanigan PM, Yagnik G, Wagner JR, De Lay M, Carrera D, Castro BA, Hayes J, Sidorov M, Garcia JLI, Eriksson P, Ronen S, Phillips J, Molinaro A, … -
Quantitative multi-modal MR imaging as a non-invasive prognostic tool for patients with recurrent low-grade glioma.
Journal of neuro-oncology 2017 Neill E, Luks T, Dayal M, Phillips JJ, Perry A, Jalbert LE, Cha S, Molinaro A, Chang SM, Nelson SJ -
Indications and Efficacy of Gamma Knife Stereotactic Radiosurgery for Recurrent Glioblastoma: 2 Decades of Institutional Experience.
Neurosurgery 2017 Imber BS, Kanungo I, Braunstein S, Barani IJ, Fogh SE, Nakamura JL, Berger MS, Chang EF, Molinaro AM, Cabrera JR, McDermott MW, Sneed PK, Aghi MK -
Body mass index, height and early-onset basal cell carcinoma in a case-control study.
Cancer epidemiology 2016 Zhang Y, Cartmel B, Choy CC, Molinaro AM, Leffell DJ, Bale AE, Mayne ST, Ferrucci LM -
GBM heterogeneity as a function of variable epidermal growth factor receptor variant III activity.
Oncotarget 2016 Lindberg OR, McKinney A, Engler JR, Koshkakaryan G, Gong H, Robinson AE, Ewald AJ, Huillard E, David James C, Molinaro AM, Shieh JT, Phillips JJ -
Cost-Effectiveness Analysis of Surgical versus Medical Treatment of Prolactinomas.
Journal of neurological surgery. Part B, Skull base 2016 Zygourakis CC, Imber BS, Chen R, Han SJ, Blevins L, Molinaro A, Kahn JG, Aghi MK -
Expression and prognostic impact of immune modulatory molecule PD-L1 in meningioma.
Journal of neuro-oncology 2016 Han SJ, Reis G, Kohanbash G, Shrivastav S, Magill ST, Molinaro AM, McDermott MW, Theodosopoulos PV, Aghi MK, Berger MS, Butowski NA, Barani I, Phillips JJ, Perry A, Okada H -
Phase I cancer clinical trials.
Neuro-oncology practice 2016 Cabrera JR, Taylor JW, Molinaro AM -
Presence of cerebral microbleeds is associated with worse executive function in pediatric brain tumor survivors.
Neuro-oncology 2016 Roddy E, Sear K, Felton E, Tamrazi B, Gauvain K, Torkildson J, Buono BD, Samuel D, Haas-Kogan DA, Chen J, Goldsby RE, Banerjee A, Lupo JM, Molinaro AM, Fullerton HJ, Mueller S -
Serial analysis of 3D H-1 MRSI for patients with newly diagnosed GBM treated with combination therapy that includes bevacizumab.
Journal of neuro-oncology 2016 Nelson SJ, Li Y, Lupo JM, Olson M, Crane JC, Molinaro A, Roy R, Clarke J, Butowski N, Prados M, Cha S, Chang SM -
Risk prediction for local versus regional/metastatic tumors after initial ductal carcinoma in situ diagnosis treated by lumpectomy.
Breast cancer research and treatment 2016 Molinaro AM, Sison JD, Ljung BM, Tlsty TD, Kerlikowske K -
Doubly robust survival trees.
Statistics in medicine 2016 Steingrimsson JA, Diao L, Molinaro AM, Strawderman RL -
Ureteral Stones: Implementation of a Reduced-Dose CT Protocol in Patients in the Emergency Department with Moderate to High Likelihood of Calculi on the Basis of STONE Score.
Radiology 2016 Moore CL, Daniels B, Singh D, Luty S, Gunabushanam G, Ghita M, Molinaro A, Gross CP -
PKM2 uses control of HuR localization to regulate p27 and cell cycle progression in human glioblastoma cells.
International journal of cancer 2016 Mukherjee J, Ohba S, See WL, Phillips JJ, Molinaro AM, Pieper RO -
Magnetic resonance analysis of malignant transformation in recurrent glioma.
Neuro-oncology 2016 Jalbert LE, Neill E, Phillips JJ, Lupo JM, Olson MP, Molinaro AM, Berger MS, Chang SM, Nelson SJ -
Stereotactic probability and variability of speech arrest and anomia sites during stimulation mapping of the language dominant hemisphere.
Journal of neurosurgery 2016 Chang EF, Breshears JD, Raygor KP, Lau D, Molinaro AM, Berger MS -
STONE PLUS: Evaluation of Emergency Department Patients With Suspected Renal Colic, Using a Clinical Prediction Tool Combined With Point-of-Care Limited Ultrasonography.
Annals of emergency medicine 2015 Daniels B, Gross CP, Molinaro A, Singh D, Luty S, Jessey R, Moore CL -
Longer genotypically-estimated leukocyte telomere length is associated with increased adult glioma risk.
Oncotarget 2015 Walsh KM, Codd V, Rice T, Nelson CP, Smirnov IV, McCoy LS, Hansen HM, Elhauge E, Ojha J, Francis SS, Madsen NR, Bracci PM, Pico AR, Molinaro AM, Tihan T, Berger MS, Chang SM, Prados MD, Jenkins RB, … -
Statistical considerations on prognostic models for glioma.
Neuro-oncology 2015 Molinaro AM, Wrensch MR, Jenkins RB, Eckel-Passow JE -
Association of Diffusion and Anatomic Imaging Parameters with Survival for Patients with Newly Diagnosed Glioblastoma Participating in Two Different Clinical Trials.
Translational oncology 2015 Wen Q, Jalilian L, Lupo JM, Li Y, Roy R, Molinaro AM, Chang SM, Prados M, Butowski N, Clarke J, Nelson SJ -
The nuts and bolts of hypothesis testing.
Neuro-oncology practice 2015 Pugh SL, Molinaro A -
A prospective Phase II clinical trial of 5-aminolevulinic acid to assess the correlation of intraoperative fluorescence intensity and degree of histologic cellularity during resection of high-grade gliomas.
Journal of neurosurgery 2015 Lau D, Hervey-Jumper SL, Chang S, Molinaro AM, McDermott MW, Phillips JJ, Berger MS -
Comparative Sensitivity of Intraoperative Motor Evoked Potential Monitoring in Predicting Postoperative Neurologic Deficits: Nondegenerative versus Degenerative Myelopathy.
Global spine journal 2015 Clark AJ, Safaee M, Chou D, Weinstein PR, Molinaro AM, Clark JP, Mummaneni PV -
Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study.
Neuro-oncology 2015 Butowski N, Colman H, De Groot JF, Omuro AM, Nayak L, Wen PY, Cloughesy TF, Marimuthu A, Haidar S, Perry A, Huse J, Phillips J, West BL, Nolop KB, Hsu HH, Ligon KL, Molinaro AM, Prados M -
DNA Methylation and Somatic Mutations Converge on the Cell Cycle and Define Similar Evolutionary Histories in Brain Tumors.
Cancer cell 2015 Mazor T, Pankov A, Johnson BE, Hong C, Hamilton EG, Bell RJA, Smirnov IV, Reis GF, Phillips JJ, Barnes MJ, Idbaih A, Alentorn A, Kloezeman JJ, Lamfers MLM, Bollen AW, Taylor BS, Molinaro AM, Olshen AB… -
New initiative for Neuro-Oncology Practice: statistics for the practicing clinician.
Neuro-oncology practice 2015 Molinaro AM -
Diagnostic tests: how to estimate the positive predictive value.
Neuro-oncology practice 2015 Molinaro AM -
Surgical assessment of the insula. Part 2: validation of the Berger-Sanai zone classification system for predicting extent of glioma resection.
Journal of neurosurgery 2015 Hervey-Jumper SL, Li J, Osorio JA, Lau D, Molinaro AM, Benet A, Berger MS -
Neurocognitive Function in Newly Diagnosed Low-grade Glioma Patients Undergoing Surgical Resection With Awake Mapping Techniques.
Neurosurgery 2015 Racine CA, Li J, Molinaro AM, Butowski N, Berger MS -
Understanding inherited genetic risk of adult glioma - a review.
Neuro-oncology practice 2015 Rice T, Lachance DH, Molinaro AM, Eckel-Passow JE, Walsh KM, Barnholtz-Sloan J, Ostrom QT, Francis SS, Wiemels J, Jenkins RB, Wiencke JK, Wrensch MR -
Impact of Timing of Concurrent Chemoradiation for Newly Diagnosed Glioblastoma: A Critical Review of Current Evidence.
Neurosurgery 2015 Han SJ, Englot DJ, Birk H, Molinaro AM, Chang SM, Clarke JL, Prados MD, Taylor JW, Berger MS, Butowski NA -
The Effect of Timing of Concurrent Chemoradiation in Patients With Newly Diagnosed Glioblastoma.
Neurosurgery 2015 Han SJ, Rutledge WC, Molinaro AM, Chang SM, Clarke JL, Prados MD, Taylor JW, Berger MS, Butowski NA -
The effects of anti-angiogenic therapy on the formation of radiation-induced microbleeds in normal brain tissue of patients with glioma.
Neuro-oncology 2015 Lupo JM, Molinaro AM, Essock-Burns E, Butowski N, Chang SM, Cha S, Nelson SJ -
Volume-staged radiosurgery for large arteriovenous malformations: an evolving paradigm.
Journal of neurosurgery 2015 Seymour ZA, Sneed PK, Gupta N, Lawton MT, Molinaro AM, Young W, Dowd CF, Halbach VV, Higashida RT, McDermott MW -
Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors.
The New England journal of medicine 2015 Eckel-Passow JE, Lachance DH, Molinaro AM, Walsh KM, Decker PA, Sicotte H, Pekmezci M, Rice T, Kosel ML, Smirnov IV, Sarkar G, Caron AA, Kollmeyer TM, Praska CE, Chada AR, Halder C, Hansen HM, McCoy … -
Telomere maintenance and the etiology of adult glioma.
Neuro-oncology 2015 Walsh KM, Wiencke JK, Lachance DH, Wiemels JL, Molinaro AM, Eckel-Passow JE, Jenkins RB, Wrensch MR -
A probabilistic map of the human ventral sensorimotor cortex using electrical stimulation.
Journal of neurosurgery 2015 Breshears JD, Molinaro AM, Chang EF -
Adverse radiation effect after stereotactic radiosurgery for brain metastases: incidence, time course, and risk factors.
Journal of neurosurgery 2015 Sneed PK, Mendez J, Vemer-van den Hoek JG, Seymour ZA, Ma L, Molinaro AM, Fogh SE, Nakamura JL, McDermott MW -
CDKN2A loss is associated with shortened overall survival in lower-grade (World Health Organization Grades II-III) astrocytomas.
Journal of neuropathology and experimental neurology 2015 Reis GF, Pekmezci M, Hansen HM, Rice T, Marshall RE, Molinaro AM, Phillips JJ, Vogel H, Wiencke JK, Wrensch MR, Walsh KM, Perry A -
Toward precision medicine in glioblastoma: the promise and the challenges.
Neuro-oncology 2015 Prados MD, Byron SA, Tran NL, Phillips JJ, Molinaro AM, Ligon KL, Wen PY, Kuhn JG, Mellinghoff IK, de Groot JF, Colman H, Cloughesy TF, Chang SM, Ryken TC, Tembe WD, Kiefer JA, Berens ME, Craig DW, … -
Awake craniotomy to maximize glioma resection: methods and technical nuances over a 27-year period.
Journal of neurosurgery 2015 Hervey-Jumper SL, Li J, Lau D, Molinaro AM, Perry DW, Meng L, Berger MS -
Indoor tanning and the MC1R genotype: risk prediction for basal cell carcinoma risk in young people.
American journal of epidemiology 2015 Molinaro AM, Ferrucci LM, Cartmel B, Loftfield E, Leffell DJ, Bale AE, Mayne ST -
Evolution of DNA repair defects during malignant progression of low-grade gliomas after temozolomide treatment.
Acta neuropathologica 2015 van Thuijl HF, Mazor T, Johnson BE, Fouse SD, Aihara K, Hong C, Malmström A, Hallbeck M, Heimans JJ, Kloezeman JJ, Stenmark-Askmalm M, Lamfers ML, Saito N, Aburatani H, Mukasa A, Berger MS, Söderkvist… -
The genetics of splicing in neuroblastoma.
Cancer discovery 2015 Chen J, Hackett CS, Zhang S, Song YK, Bell RJ, Molinaro AM, Quigley DA, Balmain A, Song JS, Costello JF, Gustafson WC, Van Dyke T, Kwok PY, Khan J, Weiss WA -
Survival and low-grade glioma: the emergence of genetic information.
Neurosurgical focus 2015 Claus EB, Walsh KM, Wiencke JK, Molinaro AM, Wiemels JL, Schildkraut JM, Bondy ML, Berger M, Jenkins R, Wrensch M -
A predictive algorithm for evaluating elevated serum prolactin in patients with a sellar mass.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2014 Cheng JS, Salinas R, Molinaro A, Chang EF, Kunwar S, Blevins L, Aghi MK -
Factors associated with failed focal neocortical epilepsy surgery.
Neurosurgery 2014 Englot DJ, Raygor KP, Molinaro AM, Garcia PA, Knowlton RC, Auguste KI, Chang EF -
Alcohol intake and early-onset basal cell carcinoma in a case-control study.
The British journal of dermatology 2014 Zhang Y, Ferrucci LM, Cartmel B, Molinaro AM, Leffell DJ, Bale AE, Mayne ST -
Accuracy of reduced-dose computed tomography for ureteral stones in emergency department patients.
Annals of emergency medicine 2014 Moore CL, Daniels B, Ghita M, Gunabushanam G, Luty S, Molinaro AM, Singh D, Gross CP -
Comparison of ADC metrics and their association with outcome for patients with newly diagnosed glioblastoma being treated with radiation therapy, temozolomide, erlotinib and bevacizumab.
Journal of neuro-oncology 2014 Wen Q, Jalilian L, Lupo JM, Molinaro AM, Chang SM, Clarke J, Prados M, Nelson SJ -
Pure germinomas of the central nervous system: treatment strategies and outcomes.
Journal of neuro-oncology 2014 Schoenfeld A, Haas-Kogan DA, Molinaro A, Banerjee A, Nicolaides T, Tihan T, Bollen AW, Gupta N, Mueller S -
Effects of adjuvant chemotherapy and radiation on overall survival in children with choroid plexus carcinoma.
Journal of neuro-oncology 2014 Sun MZ, Ivan ME, Oh MC, Delance AR, Clark AJ, Safaee M, Oh T, Kaur G, Molinaro A, Gupta N, Parsa AT -
A single-institution phase II trial of radiation, temozolomide, erlotinib, and bevacizumab for initial treatment of glioblastoma.
Neuro-oncology 2014 Clarke JL, Molinaro AM, Phillips JJ, Butowski NA, Chang SM, Perry A, Costello JF, DeSilva AA, Rabbitt JE, Prados MD -
Tea, coffee, and caffeine and early-onset basal cell carcinoma in a case-control study.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 2014 Ferrucci LM, Cartmel B, Molinaro AM, Leffell DJ, Bale AE, Mayne ST -
Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk.
Nature genetics 2014 Walsh KM, Codd V, Smirnov IV, Rice T, Decker PA, Hansen HM, Kollmeyer T, Kosel ML, Molinaro AM, McCoy LS, Bracci PM, Cabriga BS, Pekmezci M, Zheng S, Wiemels JL, Pico AR, Tihan T, Berger MS, Chang SM,… -
Derivation and validation of a clinical prediction rule for uncomplicated ureteral stone--the STONE score: retrospective and prospective observational cohort studies.
BMJ (Clinical research ed.) 2014 Moore CL, Bomann S, Daniels B, Luty S, Molinaro A, Singh D, Gross CP -
Phase II trial of 7 days on/7 days off temozolmide for recurrent high-grade glioma.
Neuro-oncology 2014 Han SJ, Rolston JD, Molinaro AM, Clarke JL, Prados MD, Chang SM, Berger MS, DeSilva A, Butowski NA -
Effect of provider experience on clinician-performed ultrasonography for hydronephrosis in patients with suspected renal colic.
Annals of emergency medicine 2014 Herbst MK, Rosenberg G, Daniels B, Gross CP, Singh D, Molinaro AM, Luty S, Moore CL -
Characterization of metabolites in infiltrating gliomas using ex vivo ¹H high-resolution magic angle spinning spectroscopy.
NMR in biomedicine 2014 Elkhaled A, Jalbert L, Constantin A, Yoshihara HA, Phillips JJ, Molinaro AM, Chang SM, Nelson SJ -
Cavernous and inferior petrosal sinus sampling and dynamic magnetic resonance imaging in the preoperative evaluation of Cushing's disease.
Journal of neuro-oncology 2014 Potts MB, Shah JK, Molinaro AM, Blevins LS, Tyrrell JB, Kunwar S, Dowd CF, Hetts SW, Aghi MK -
Gross total resection improves overall survival in children with choroid plexus carcinoma.
Journal of neuro-oncology 2013 Sun MZ, Ivan ME, Clark AJ, Oh MC, Delance AR, Oh T, Safaee M, Kaur G, Bloch O, Molinaro A, Gupta N, Parsa AT -
Trends in surgical treatment for trigeminal neuralgia in the United States of America from 1988 to 2008.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2013 Wang DD, Ouyang D, Englot DJ, Rolston JD, Molinaro AM, Ward M, Chang EF -
Genetic variants in telomerase-related genes are associated with an older age at diagnosis in glioma patients: evidence for distinct pathways of gliomagenesis.
Neuro-oncology 2013 Walsh KM, Rice T, Decker PA, Kosel ML, Kollmeyer T, Hansen HM, Zheng S, McCoy LS, Bracci PM, Anderson E, Hsuang G, Wiemels JL, Pico AR, Smirnov I, Molinaro AM, Tihan T, Berger MS, Chang SM, Prados MD,… -
Prevalence and clinical importance of alternative causes of symptoms using a renal colic computed tomography protocol in patients with flank or back pain and absence of pyuria.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2013 Moore CL, Daniels B, Singh D, Luty S, Molinaro A -
The relative patient benefit of gross total resection in adult choroid plexus papillomas.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2013 Safaee M, Oh MC, Sughrue ME, Delance AR, Bloch O, Sun M, Kaur G, Molinaro AM, Parsa AT -
PDGFRA amplification is common in pediatric and adult high-grade astrocytomas and identifies a poor prognostic group in IDH1 mutant glioblastoma.
Brain pathology (Zurich, Switzerland) 2013 Phillips JJ, Aranda D, Ellison DW, Judkins AR, Croul SE, Brat DJ, Ligon KL, Horbinski C, Venneti S, Zadeh G, Santi M, Zhou S, Appin CL, Sioletic S, Sullivan LM, Martinez-Lage M, Robinson AE, Yong WH, … -
Poly (ADP-Ribose) polymerase inhibitor MK-4827 together with radiation as a novel therapy for metastatic neuroblastoma.
Anticancer research 2013 Mueller S, Bhargava S, Molinaro AM, Yang X, Kolkowitz I, Olow A, Wehmeijer N, Orbach S, Chen J, Matthay KK, Haas-Kogan DA -
Using susceptibility-weighted imaging to determine response to combined anti-angiogenic, cytotoxic, and radiation therapy in patients with glioblastoma multiforme.
Neuro-oncology 2013 Lupo JM, Essock-Burns E, Molinaro AM, Cha S, Chang SM, Butowski N, Nelson SJ -
Prognosis by tumor location in adults with spinal ependymomas.
Journal of neurosurgery. Spine 2013 Oh MC, Kim JM, Kaur G, Safaee M, Sun MZ, Singh A, Aranda D, Molinaro AM, Parsa AT -
Prognosis by tumor location for pediatric spinal cord ependymomas.
Journal of neurosurgery. Pediatrics 2012 Oh MC, Sayegh ET, Safaee M, Sun MZ, Kaur G, Kim JM, Aranda D, Molinaro AM, Gupta N, Parsa AT -
Comparison of DSC-MRI post-processing techniques in predicting microvascular histopathology in patients newly diagnosed with GBM.
Journal of magnetic resonance imaging : JMRI 2012 Essock-Burns E, Phillips JJ, Molinaro AM, Lupo JM, Cha S, Chang SM, Nelson SJ -
RTOG 0211: a phase 1/2 study of radiation therapy with concurrent gefitinib for newly diagnosed glioblastoma patients.
International journal of radiation oncology, biology, physics 2012 Chakravarti A, Wang M, Robins HI, Lautenschlaeger T, Curran WJ, Brachman DG, Schultz CJ, Choucair A, Dolled-Filhart M, Christiansen J, Gustavson M, Molinaro A, Mischel P, Dicker AP, Bredel M, Mehta M -
Increased microglia/macrophage gene expression in a subset of adult and pediatric astrocytomas.
PloS one 2012 Engler JR, Robinson AE, Smirnov I, Hodgson JG, Berger MS, Gupta N, James CD, Molinaro A, Phillips JJ -
Regional variation in histopathologic features of tumor specimens from treatment-naive glioblastoma correlates with anatomic and physiologic MR Imaging.
Neuro-oncology 2012 Barajas RF, Phillips JJ, Parvataneni R, Molinaro A, Essock-Burns E, Bourne G, Parsa AT, Aghi MK, McDermott MW, Berger MS, Cha S, Chang SM, Nelson SJ -
Hypoxia-induced autophagy promotes tumor cell survival and adaptation to antiangiogenic treatment in glioblastoma.
Cancer research 2012 Hu YL, DeLay M, Jahangiri A, Molinaro AM, Rose SD, Carbonell WS, Aghi MK -
Stathmin expression and its relationship to microtubule-associated protein tau and outcome in breast cancer.
Cancer 2012 Baquero MT, Hanna JA, Neumeister V, Cheng H, Molinaro AM, Harris LN, Rimm DL -
Lifetime history of indoor tanning in young people: a retrospective assessment of initiation, persistence, and correlates.
BMC public health 2012 Lostritto K, Ferrucci LM, Cartmel B, Leffell DJ, Molinaro AM, Bale AE, Mayne ST -
Indoor tanning and risk of early-onset basal cell carcinoma.
Journal of the American Academy of Dermatology 2011 Ferrucci LM, Cartmel B, Molinaro AM, Leffell DJ, Bale AE, Mayne ST -
Host phenotype characteristics and MC1R in relation to early-onset basal cell carcinoma.
The Journal of investigative dermatology 2011 Ferrucci LM, Cartmel B, Molinaro AM, Gordon PB, Leffell DJ, Bale AE, Mayne ST -
Evaluation of prognostic and predictive value of microtubule associated protein tau in two independent cohorts.
Breast cancer research : BCR 2011 Baquero MT, Lostritto K, Gustavson MD, Bassi KA, Appia F, Camp RL, Molinaro AM, Harris LN, Rimm DL -
Natural history and surgical management of incidentally discovered low-grade gliomas.
Journal of neurosurgery 2011 Potts MB, Smith JS, Molinaro AM, Berger MS -
Rathke cleft cysts in pediatric patients: presentation, surgical management, and postoperative outcomes.
Neurosurgical focus 2011 Jahangiri A, Molinaro AM, Tarapore PE, Blevins L, Auguste KI, Gupta N, Kunwar S, Aghi MK -
Plasma markers for identifying patients with metastatic melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011 Kluger HM, Hoyt K, Bacchiocchi A, Mayer T, Kirsch J, Kluger Y, Sznol M, Ariyan S, Molinaro A, Halaban R -
Comparing the use of diagnostic imaging and receipt of carotid endarterectomy in elderly black and white stroke patients.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2011 Martin KD, Naert L, Goldstein LB, Kasl S, Molinaro AM, Lichtman JH -
A Variant in a MicroRNA complementary site in the 3' UTR of the KIT oncogene increases risk of acral melanoma.
Oncogene 2010 Godshalk SE, Paranjape T, Nallur S, Speed W, Chan E, Molinaro AM, Bacchiocchi A, Hoyt K, Tworkoski K, Stern DF, Sznol M, Ariyan S, Lazova R, Halaban R, Kidd KK, Weidhaas JB, Slack FJ -
A phase 2 trial of dasatinib in advanced melanoma.
Cancer 2010 Kluger HM, Dudek AZ, McCann C, Ritacco J, Southard N, Jilaveanu LB, Molinaro A, Sznol M -
Biomarker expression and risk of subsequent tumors after initial ductal carcinoma in situ diagnosis.
Journal of the National Cancer Institute 2010 Kerlikowske K, Molinaro AM, Gauthier ML, Berman HK, Waldman F, Bennington J, Sanchez H, Jimenez C, Stewart K, Chew K, Ljung BM, Tlsty TD -
STATISTICALBIOINFORMATICS: A GUIDE FOR LIFE AND BIOMEDICAL SCIENCE RESEARCHERS. Ed. Jae K. Lee
Statistical resampling for large screening data analysis such as classical resampling Bootstrapping, Markov chain Monte Carlo, and statistical simulation and validation strategies 2010 Molinaro AM and Lostritto K -
Melanoma prognostic model using tissue microarrays and genetic algorithms.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009 Gould Rothberg BE, Berger AJ, Molinaro AM, Subtil A, Krauthammer MO, Camp RL, Bradley WR, Ariyan S, Kluger HM, Rimm DL -
Genome-wide screen of promoter methylation identifies novel markers in melanoma.
Genome research 2009 Koga Y, Pelizzola M, Cheng E, Krauthammer M, Sznol M, Ariyan S, Narayan D, Molinaro AM, Halaban R, Weissman SM -
Integrative analysis of epigenetic modulation in melanoma cell response to decitabine: clinical implications.
PloS one 2009 Halaban R, Krauthammer M, Pelizzola M, Cheng E, Kovacs D, Sznol M, Ariyan S, Narayan D, Bacchiocchi A, Molinaro A, Kluger Y, Deng M, Tran N, Zhang W, Picardo M, Enghild JJ -
A preliminary mathematical model of skin dendritic cell trafficking and induction of t-cell immunity
Discrete and Continuous Dynamical Systems - Series B (DCDS-B): Special Issue on Mathematical Biology and Medicine 2009 Erickson AH, Wise A, Fleming S, Molinaro AM, Teboh-Ewungkem M, Baird M, Lateef Z, and de Pillis L -
AQUA analysis of thymidylate synthase reveals localization to be a key prognostic biomarker in 2 large cohorts of colorectal carcinoma.
Archives of pathology & laboratory medicine 2008 Gustavson MD, Molinaro AM, Tedeschi G, Camp RL, Rimm DL -
Comparison of quantitative immunofluorescence with conventional methods for HER2/neu testing with respect to response to trastuzumab therapy in metastatic breast cancer.
Archives of pathology & laboratory medicine 2008 Giltnane JM, Molinaro A, Cheng H, Robinson A, Turbin D, Gelmon K, Huntsman D, Rimm DL -
High levels of vascular endothelial growth factor and its receptors (VEGFR-1, VEGFR-2, neuropilin-1) are associated with worse outcome in breast cancer.
Human pathology 2008 Ghosh S, Sullivan CA, Zerkowski MP, Molinaro AM, Rimm DL, Camp RL, Chung GG -
Classification of renal cell carcinoma based on expression of VEGF and VEGF receptors in both tumor cells and endothelial cells.
Laboratory investigation; a journal of technical methods and pathology 2008 Kluger HM, Siddiqui SF, Angeletti C, Sznol M, Kelly WK, Molinaro AM, Camp RL -
Cross-Validated Bagged Learning.
Journal of multivariate analysis 2008 Petersen ML, Molinaro AM, Sinisi SE, van der Laan MJ -
Quantitative justification of the change from 10% to 30% for human epidermal growth factor receptor 2 scoring in the American Society of Clinical Oncology/College of American Pathologists guidelines: tumor heterogeneity in breast cancer and its implications for tissue microarray based assessment of outcome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007 Moeder CB, Giltnane JM, Harigopal M, Molinaro A, Robinson A, Gelmon K, Huntsman D, Camp RL, Rimm DL, American Society of Clinical Oncology, College of American Pathologists -
Clinical and pathological findings in a HERDA-affected foal for 1.5 years of life.
Veterinary dermatology 2007 White SD, Affolter VK, Schultheiss PC, Ball BA, Wessel MT, Kass P, Molinaro AM, Bannasch DL, Ihrke PJ -
Evaluation of apolipoprotein A1 and posttranslationally modified forms of transthyretin as biomarkers for ovarian cancer detection in an independent study population.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006 Moore LE, Fung ET, McGuire M, Rabkin CC, Molinaro A, Wang Z, Zhang F, Wang J, Yip C, Meng XY, Pfeiffer RM -
Survival ensembles.
Biostatistics (Oxford, England) 2005 Hothorn T, Bühlmann P, Dudoit S, Molinaro A, van der Laan MJ -
Tree-based multivariate regression and density estimation with right-censored data
Journal of Multivariate Analysis 2004 Molinaro AM, Dudoit S, and van der Laan MJ -
Characteristics associated with recurrence among women with ductal carcinoma in situ treated by lumpectomy.
Journal of the National Cancer Institute 2003 Kerlikowske K, Molinaro A, Cha I, Ljung BM, Ernster VL, Stewart K, Chew K, Moore DH, Waldman F -
Loss-based estimation with cross-validation: Applications to microarray data analysis and motif finding
SIGKDD Explorations 2003 Dudoit S, van der Laan MJ, Keles¸ S, Molinaro AM, Sinisi S, and Teng SL -
The apc/beta-catenin pathway in ulcerative colitis-related colorectal carcinomas: A mutational analysis
Cancer 2002 Aust DE, Terdiman JP, Willenbucher RF, Chang CG, Molinaro AM, Baretton GB, Loehrs U, and Waldman FM -
Loss of chromosome 16q in lobular carcinoma in situ.
Human pathology 2001 Etzell JE, Devries S, Chew K, Florendo C, Molinaro A, Ljung BM, Waldman FM -
Altered Distribution of beta-catenin, and its binding proteins E-cadherin and APC, in Ulcerative Colitis-Related Colorectal Cancers
Modern Pathology 2001 Aust DE, Terdiman JP, Willenbucher RF, Chew K, Ferrell L, Florendo C, Molinaro AM, Baretton GB, Loehrs U, Waldman, FM -
Chromosomal Alterations in Ulcerative Colitis-Related and Sporadic Colorectal Cancers by Comparative Genomic Hybridization
Human Pathology 2000 Aust DE, Willenbucher RF, Terdiman JP, Ferrell LD, Chang CG, Moore DH, Molinaro AM, Baretton GB, Loehrs U, Waldman FM.