Anne Deucher, MD, PhD
Professor
Laboratory Medicine
School of Medicine

My research publications have covered a wide range of topics, including the performance of nucleic amplification tests for COVID-19, the identification of potential targets for CAR-T cell therapy in leukemia, and the investigation of bone marrow necrosis. I have contributed to the understanding of DNA-binding proteins and microsatellite repeats in the context of bone marrow diseases. My work continues to advance our knowledge in the field of laboratory medicine, with a focus on improving diagnostic accuracy and patient care.

• BCL6 expression correlates with the t(1;19) translocation in B-lymphoblastic leukemia.
  American journal of clinical pathology 2015 Deucher AM, Qi Z, Yu J, George TI, Etzell JE
• Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia.
  Cancer cell 2015 Geng H, Hurtz C, Lenz KB, Chen Z, Baumjohann D, Thompson S, Goloviznina NA, Chen WY, Huan J, LaTocha D, Ballabio E, Xiao G, Lee JW, Deucher A, Qi Z, Park E, Huang C, Nahar R, Kweon SM, Shojaee S, Chan…
• Bone marrow necrosis: ten-year retrospective review of bone marrow biopsy specimens.
  American journal of clinical pathology 2015 Wool GD, Deucher A
• Rare sequence variation in the genome flanking a short tandem repeat locus can lead to a question of "nonmaternity".
  The Journal of molecular diagnostics : JMD 2010 Deucher A, Chiang T, Schrijver I
• Regulation of involucrin gene expression.
  The Journal of investigative dermatology 2004 Eckert RL, Crish JF, Efimova T, Dashti SR, Deucher A, Bone F, Adhikary G, Huang G, Gopalakrishnan R, Balasubramanian S
• A novel tumor suppressor protein promotes keratinocyte terminal differentiation via activation of type I transglutaminase.
  The Journal of biological chemistry 2003 Sturniolo MT, Dashti SR, Deucher A, Rorke EA, Broome AM, Chandraratna RA, Keepers T, Eckert RL
• Keratinocyte survival, differentiation, and death: many roads lead to mitogen-activated protein kinase.
  The journal of investigative dermatology. Symposium proceedings 2002 Eckert RL, Efimova T, Dashti SR, Balasubramanian S, Deucher A, Crish JF, Sturniolo M, Bone F
• Novel protein kinase C isoforms regulate human keratinocyte differentiation by activating a p38 delta mitogen-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha.
  The Journal of biological chemistry 2002 Efimova T, Deucher A, Kuroki T, Ohba M, Eckert RL
• Calcium-dependent involucrin expression is inversely regulated by protein kinase C (PKC)alpha and PKCdelta.
  The Journal of biological chemistry 2002 Deucher A, Efimova T, Eckert RL
• The carboxy-terminal hydrophobic domain of TIG3, a class II tumor suppressor protein, is required for appropriate cellular localization and optimal biological activity.
  International journal of oncology 2000 Deucher A, Nagpal S, Chandraratna RA, Di Sepio D, Robinson NA, Dashti SR, Eckert RL
• Expression of a retinoid-inducible tumor suppressor, Tazarotene-inducible gene-3, is decreased in psoriasis and skin cancer.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2000 Duvic M, Helekar B, Schulz C, Cho M, DiSepio D, Hager C, DiMao D, Hazarika P, Jackson B, Breuer-McHam J, Young J, Clayman G, Lippman SM, Chandraratna RA, Robinson NA, Deucher A, Eckert RL, Nagpal S
• Identification and characterization of a retinoid-induced class II tumor suppressor/growth regulatory gene.
  Proceedings of the National Academy of Sciences of the United States of America 1998 DiSepio D, Ghosn C, Eckert RL, Deucher A, Robinson N, Duvic M, Chandraratna RA, Nagpal S
• Growth hormone and aging change rat liver fatty acid binding protein levels.
  Journal of the American College of Nutrition 1996 Singer SS, Henkels K, Deucher A, Barker M, Singer J, Trulzsch DV