Annabelle Charbit, PhD
Postdoc Employee
Cardiovascular Research Inst
School of Medicine

Publications (20)

Top publication keywords:
Calcitonin Gene-Related PeptideReceptors, DopamineAsthmaTrigeminal NerveMucusTrigeminal Nucleus, SpinalDopamineDeoxyribonuclease IDopaminergic NeuronsSputumTrigeminal Caudal NucleusPeripheral Nervous SystemHypothalamusEosinophil PeroxidaseEosinophils

• Cellular and molecular features of asthma mucus plugs provide clues about their formation and persistence.
  The Journal of clinical investigation 2025 Liegeois MA, Hsieh A, Al-Fouadi M, Charbit AR, Yang CX, Hackett TL, Fahy JV
• Response to the Editor Regarding: "In Office Sampling of Eosinophil Peroxidase to Diagnose Eosinophilic Chronic Rhinosinusitis".
  International forum of allergy & rhinology 2025 Callander JK, Charbit AR, Khanna K, Fahy JV, Tang M, Liegeois M, Pletcher SD, Goldberg AN, Gurrola JG, Murr AH, Butrymowicz A, Loftus PA
• In office sampling of eosinophil peroxidase to diagnose eosinophilic chronic rhinosinusitis.
  International forum of allergy & rhinology 2024 Callander JK, Charbit AR, Khanna K, Fahy JV, Tang M, Liegeois M, Pletcher SD, Goldberg AN, Gurrola JG, Murr AH, Butrymowicz A, Loftus PA
• Peroxidase-mediated mucin cross-linking drives pathologic mucus gel formation in IL-13-stimulated airway epithelial cells.
  JCI insight 2024 Liegeois MA, Braunreuther M, Charbit AR, Raymond WW, Tang M, Woodruff PG, Christenson SA, Castro M, Erzurum SC, Israel E, Jarjour NN, Levy BD, Moore WC, Wenzel SE, Fuller GG, Fahy JV
• A novel DNase assay reveals low DNase activity in severe asthma.
  American journal of physiology. Lung cellular and molecular physiology 2024 Charbit AR, Liegeois MA, Raymond WW, Comhair SAA, Johansson MW, Hastie AT, Bleecker ER, Fajt M, Castro M, Sumino K, Erzurum SC, Israel E, Jarjour NN, Mauger DT, Moore WC, Wenzel SE, Woodruff PG, Levy …

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• Utility of eosinophil peroxidase as a biomarker of eosinophilic inflammation in asthma.
  The Journal of allergy and clinical immunology 2024 Tang M, Charbit AR, Johansson MW, Jarjour NN, Denlinger LC, Raymond WW, Peters MC, Dunican EM, Castro M, Sumino K, Erzurum SC, Comhair SA, Moore WC, Levy BD, Israel E, Phipatanakul W, Phillips BR, …
• A novel thiol-saccharide mucolytic for the treatment of muco-obstructive lung diseases.
  The European respiratory journal 2023 Addante A, Raymond W, Gitlin I, Charbit A, Orain X, Scheffler AW, Kuppe A, Duerr J, Daniltchenko M, Drescher M, Graeber SY, Healy AM, Oscarson S, Fahy JV, Mall MA
• Exploring antiviral and anti-inflammatory effects of thiol drugs in COVID-19.
  American journal of physiology. Lung cellular and molecular physiology 2022 Khanna K, Raymond WW, Jin J, Charbit AR, Gitlin I, Tang M, Werts AD, Barrett EG, Cox JM, Birch SM, Martinelli R, Sperber HS, Franz S, Duff T, Hoffmann M, Healy AM, Oscarson S, Pöhlmann S, Pillai SK, …
• Thiol drugs decrease SARS-CoV-2 lung injury in vivo and disrupt SARS-CoV-2 spike complex binding to ACE2 in vitro.
  bioRxiv : the preprint server for biology 2021 Khanna K, Raymond W, Jin J, Charbit AR, Gitlin I, Tang M, Werts AD, Barrett EG, Cox JM, Birch SM, Martinelli R, Sperber HS, Franz S, Pillai S, Healy AM, Duff T, Oscarson S, Hoffmann M, Pöhlmann S, …
• An anti-siglec-8 antibody depletes sputum eosinophils from asthmatic subjects and inhibits lung mast cells.
  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2020 Kerr SC, Gonzalez JR, Schanin J, Peters MC, Lambrecht BN, Brock EC, Charbit A, Ansel KM, Youngblood BA, Fahy JV
• A Midbrain Circuit that Mediates Headache Aversiveness in Rats.
  Cell reports 2019 Waung MW, Margolis EB, Charbit AR, Fields HL
• Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma.
  American journal of respiratory and critical care medicine 2019 Lachowicz-Scroggins ME, Dunican EM, Charbit AR, Raymond W, Looney MR, Peters MC, Gordon ED, Woodruff PG, Lefrançais E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, …
• Relative contributions and mapping of ventral tegmental area dopamine and GABA neurons by projection target in the rat.
  The Journal of comparative neurology 2018 Breton JM, Charbit AR, Snyder BJ, Fong PTK, Dias EV, Himmels P, Lock H, Margolis EB
• Trigeminocervical complex responses after lesioning dopaminergic A11 nucleus are modified by dopamine and serotonin mechanisms.
  Pain 2011 Charbit AR, Akerman S, Goadsby PJ
• Modulation of nocioceptive transmission with calcitonin gene-related peptide receptor antagonists in the thalamus.
  Brain : a journal of neurology 2010 Summ O, Charbit AR, Andreou AP, Goadsby PJ
• Dopamine: what's new in migraine?
  Current opinion in neurology 2010 Charbit AR, Akerman S, Goadsby PJ
• Animal models of headache: from bedside to bench and back to bedside.
  Expert review of neurotherapeutics 2010 Andreou AP, Summ O, Charbit AR, Romero-Reyes M, Goadsby PJ
• ENU mutagenesis reveals a novel phenotype of reduced limb strength in mice lacking fibrillin 2.
  PloS one 2010 Miller G, Neilan M, Chia R, Gheryani N, Holt N, Charbit A, Wells S, Tucci V, Lalanne Z, Denny P, Fisher EM, Cheeseman M, Askew GN, Dear TN
• Neurons of the dopaminergic/calcitonin gene-related peptide A11 cell group modulate neuronal firing in the trigeminocervical complex: an electrophysiological and immunohistochemical study.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Charbit AR, Akerman S, Holland PR, Goadsby PJ
• Comparison of the effects of central and peripheral dopamine receptor activation on evoked firing in the trigeminocervical complex.
  The Journal of pharmacology and experimental therapeutics 2009 Charbit AR, Akerman S, Goadsby PJ