Andrew Latham, PhD
Postdoctoral Scholar
Bioengineering
School of Pharmacy

Publications (15)

Top publication keywords:
RibonucleasesChromatinProof of Concept StudyDNAPhase TransitionProtein ConformationMolecular Dynamics SimulationProteinsX-Ray DiffractionIntrinsically Disordered ProteinsScattering, Small AngleEntropyNucleosomesHistonesCell Nucleolus

• Microphase Separation Produces Interfacial Environment within Diblock Biomolecular Condensates.
  bioRxiv : the preprint server for biology 2024 Latham AP, Zhu L, Sharon DA, Ye S, Willard AP, Zhang X, Zhang B
• Utilizing Molecular Simulations to Examine Nanosuspension Stability.
  Pharmaceutics 2023 Latham AP, Levy ES, Sellers BD, Leung DH
• Micropolarity governs the structural organization of biomolecular condensates.
  Nature chemical biology 2023 Ye S, Latham AP, Tang Y, Hsiung CH, Chen J, Luo F, Liu Y, Zhang B, Zhang X
• OpenABC enables flexible, simplified, and efficient GPU accelerated simulations of biomolecular condensates.
  PLoS computational biology 2023 Liu S, Wang C, Latham AP, Ding X, Zhang B
• Micropolarity governs the structural organization of biomolecular condensates.
  bioRxiv : the preprint server for biology 2023 Ye S, Latham AP, Tang Y, Hsiung CH, Chen J, Luo F, Liu Y, Zhang B, Zhang X

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• Molecular Determinants for the Layering and Coarsening of Biological Condensates.
  Aggregate (Hoboken, N.J.) 2022 Latham AP, Zhang B
• Single-stranded nucleic acid binding and coacervation by linker histone H1.
  Nature structural & molecular biology 2022 Leicher R, Osunsade A, Chua GNL, Faulkner SC, Latham AP, Watters JW, Nguyen T, Beckwitt EC, Christodoulou-Rubalcava S, Young PG, Zhang B, David Y, Liu S
• On the stability and layered organization of protein-DNA condensates.
  Biophysical journal 2022 Latham AP, Zhang B
• Unifying coarse-grained force fields for folded and disordered proteins.
  Current opinion in structural biology 2021 Latham AP, Zhang B
• Multiscale modeling of genome organization with maximum entropy optimization.
  The Journal of chemical physics 2021 Lin X, Qi Y, Latham AP, Zhang B
• Consistent Force Field Captures Homologue-Resolved HP1 Phase Separation.
  Journal of chemical theory and computation 2021 Latham AP, Zhang B
• Phosphorylation-Dependent Conformations of the Disordered Carboxyl-Terminus Domain in the Epidermal Growth Factor Receptor.
  The journal of physical chemistry letters 2020 Regmi R, Srinivasan S, Latham AP, Kukshal V, Cui W, Zhang B, Bose R, Schlau-Cohen GS
• Structure and Dynamics of N-Glycosylated Human Ribonuclease 1.
  Biochemistry 2020 Kilgore HR, Latham AP, Ressler VT, Zhang B, Raines RT
• Maximum Entropy Optimized Force Field for Intrinsically Disordered Proteins.
  Journal of chemical theory and computation 2019 Latham AP, Zhang B
• Improving Coarse-Grained Protein Force Fields with Small-Angle X-ray Scattering Data.
  The journal of physical chemistry. B 2019 Latham AP, Zhang B