Andrew Connolly, MD, PhD
Professor
Pathology
School of Medicine

Dr. Connolly is the Director of the UCSF Autopsy Service and Cardiovascular Pathology Service. He has longstanding research interests in cardiovascular biology and pathology, with a particular focus recently on cardiomyocyte gene expression in heart disease.

Awards

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• Mathers Teaching Award, Stanford University, 2015
• Kaiser Teaching Award, Stanford University, 2013
• Kaiser Teaching Award, Stanford University, 2010
• Mathers Teaching Award, Stanford University, 2009
• Kaiser Teaching Award, Stanford University, 2006
• Summa cum laude, Princeton University, Princeton University, 1984

Education & Training

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• PhD Biomedical Sciences UCSF 06/1997
• Residency Anatomic Pathology UCSF 06/1992
• MD Medicine Harvard Medical School 06/1989
• AB Chemistry Princeton University 06/1984

Interests

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• Cardiovascular Pathology
• Autopsy Pathology

Websites

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• Autopsy Pathology Online Resources (autopsypathology.net)

Grants and Projects

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• Transgenic Models of Thrombin Receptor Function, NIH, 1995-2000

Publications (91)

Top publication keywords:
Myocytes, CardiacStem Cell TransplantationPersonality DisordersEmbryonic Stem CellsDeath, Sudden, CardiacIslets of LangerhansCD47 AntigenPluripotent Stem CellsMyocytes, Smooth MuscleIslets of Langerhans TransplantationTeratomaVentricular Dysfunction, RightGenes, ReporterReceptors, ThrombinMarfan Syndrome

• Observation of Seven Astrophysical Tau Neutrino Candidates with IceCube.
  Physical review letters 2024 Abbasi R, Ackermann M, Adams J, Agarwalla SK, Aguilar JA, Ahlers M, Alameddine JM, Amin NM, Andeen K, Anton G, Argüelles C, Ashida Y, Athanasiadou S, Axani SN, Bai X, Balagopal VA, Baricevic M, …
• Mechanical Dispersion Discriminates Between Arrhythmic and Nonarrhythmic Sudden Death: From the POST SCD Study.
  JACC. Clinical electrophysiology 2024 Tastet L, Ramakrishna S, Lim LJ, Bibby D, Olgin JE, Connolly AJ, Moffatt E, Tseng ZH, Delling FN
• Hypoimmune islets achieve insulin independence after allogeneic transplantation in a fully immunocompetent non-human primate.
  Cell stem cell 2024 Hu X, White K, Young C, Olroyd AG, Kievit P, Connolly AJ, Deuse T, Schrepfer S
• Clinical and biological heterogeneity of multisystem inflammatory syndrome in adults following SARS-CoV-2 infection: a case series.
  Frontiers in medicine 2023 Barth KE, Spottiswoode N, Hurabielle C, Subbaraj L, COMET Consortium, Calfee CS, Matthay MA, French S, Connolly A, Hewitt SM, Vannella KM, Barnett C, Langelier CR, Patterson S
• Observation of high-energy neutrinos from the Galactic plane.
  Science (New York, N.Y.) 2023 IceCube Collaboration*†, Abbasi R, Ackermann M, Adams J, Aguilar JA, Ahlers M, Ahrens M, Alameddine JM, Alves AA, Amin NM, Andeen K, Anderson T, Anton G, Argüelles C, Ashida Y, Athanasiadou S, Axani S…

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• Mechanical Dispersion Discriminates between Arrhythmic and Non-Arrhythmic Sudden Death: From the POST SCD Study.
  medRxiv : the preprint server for health sciences 2023 Tastet L, Ramakrishna S, Lim LJ, Bibby D, Olgin JE, Connolly AJ, Moffatt E, Tseng ZH, Delling FN
• Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques.
  Nature biotechnology 2023 Hu X, White K, Olroyd AG, DeJesus R, Dominguez AA, Dowdle WE, Friera AM, Young C, Wells F, Chu EY, Ito CE, Krishnapura H, Jain S, Ankala R, McGill TJ, Lin A, Egenberger K, Gagnon A, Michael Rukstalis …
• Human hypoimmune primary pancreatic islets avoid rejection and autoimmunity and alleviate diabetes in allogeneic humanized mice.
  Science translational medicine 2023 Hu X, Gattis C, Olroyd AG, Friera AM, White K, Young C, Basco R, Lamba M, Wells F, Ankala R, Dowdle WE, Lin A, Egenberger K, Rukstalis JM, Millman JR, Connolly AJ, Deuse T, Schrepfer S
• Induction and Phenotyping of Acute Right Heart Failure in a Large Animal Model of Chronic Thromboembolic Pulmonary Hypertension.
  Journal of visualized experiments : JoVE 2022 Boulate D, Amsallem M, Menager JB, Dang Van S, Dorfmuller P, Connolly A, Todesco A, Decante B, Fadel E, Haddad F, Mercier O
• Relative strain is a novel predictor of aneurysmal degeneration of the thoracic aorta: An ex vivo mechanical study.
  JVS-vascular science 2021 Chiu P, Lee HP, Dalal AR, Koyano T, Nguyen M, Connolly AJ, Chaudhuri O, Fischbein MP
• Hypoimmune induced pluripotent stem cell-derived cell therapeutics treat cardiovascular and pulmonary diseases in immunocompetent allogeneic mice.
  Proceedings of the National Academy of Sciences of the United States of America 2021 Deuse T, Tediashvili G, Hu X, Gravina A, Tamenang A, Wang D, Connolly A, Mueller C, Mallavia B, Looney MR, Alawi M, Lanier LL, Schrepfer S
• Sudden Cardiac Death and Myocardial Fibrosis, Determined by Autopsy, in Persons with HIV.
  The New England journal of medicine 2021 Tseng ZH, Moffatt E, Kim A, Vittinghoff E, Ursell P, Connolly A, Olgin JE, Wong JK, Hsue PY
• Positive Controls in Adults and Children Support That Very Few, If Any, New Neurons Are Born in the Adult Human Hippocampus.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 Sorrells SF, Paredes MF, Zhang Z, Kang G, Pastor-Alonso O, Biagiotti S, Page CE, Sandoval K, Knox A, Connolly A, Huang EJ, Garcia-Verdugo JM, Oldham MC, Yang Z, Alvarez-Buylla A
• Antemortem and Post-Mortem Characteristics of Lethal Mitral Valve Prolapse Among All Countywide Sudden Deaths.
  JACC. Clinical electrophysiology 2021 Delling FN, Aung S, Vittinghoff E, Dave S, Lim LJ, Olgin JE, Connolly A, Moffatt E, Tseng ZH
• Zmat3 Is a Key Splicing Regulator in the p53 Tumor Suppression Program.
  Molecular cell 2020 Bieging-Rolett KT, Kaiser AM, Morgens DW, Boutelle AM, Seoane JA, Van Nostrand EL, Zhu C, Houlihan SL, Mello SS, Yee BA, McClendon J, Pierce SE, Winters IP, Wang M, Connolly AJ, Lowe SW, Curtis C, Yeo…
• BRD4 (Bromodomain-Containing Protein 4) Interacts with GATA4 (GATA Binding Protein 4) to Govern Mitochondrial Homeostasis in Adult Cardiomyocytes.
  Circulation 2020 Padmanabhan A, Alexanian M, Linares-Saldana R, González-Terán B, Andreoletti G, Huang Y, Connolly AJ, Kim W, Hsu A, Duan Q, Winchester SAB, Felix F, Perez-Bermejo JA, Wang Q, Li L, Shah PP, Haldar SM,…
• Novel and lethal case of cardiac involvement in DNM1L mitochondrial encephalopathy.
  American journal of medical genetics. Part A 2019 Vandeleur D, Chen CV, Huang EJ, Connolly AJ, Sanchez H, Moon-Grady AJ
• Anatomically specific reactive oxygen species production participates in Marfan syndrome aneurysm formation.
  Journal of cellular and molecular medicine 2019 Emrich F, Penov K, Arakawa M, Dhablania N, Burdon G, Pedroza AJ, Koyano TK, Kim YM, Raaz U, Connolly AJ, Iosef C, Fischbein MP
• Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure.
  Nature communications 2019 Cordero P, Parikh VN, Chin ET, Erbilgin A, Gloudemans MJ, Shang C, Huang Y, Chang AC, Smith KS, Dewey F, Zaleta K, Morley M, Brandimarto J, Glazer N, Waggott D, Pavlovic A, Zhao M, Moravec CS, Tang …
• Statins Reduce Thoracic Aortic Aneurysm Growth in Marfan Syndrome Mice via Inhibition of the Ras-Induced ERK (Extracellular Signal-Regulated Kinase) Signaling Pathway.
  Journal of the American Heart Association 2018 Sato T, Arakawa M, Tashima Y, Tsuboi E, Burdon G, Trojan J, Koyano T, Youn YN, Penov K, Pedroza AJ, Shabazzi M, Palmon I, Nguyen MN, Connolly AJ, Yamaguchi A, Fischbein MP
• Two patients with FOXF1 mutations with alveolar capillary dysplasia with misalignment of pulmonary veins and other malformations: Two different presentations and outcomes.
  American journal of medical genetics. Part A 2018 Abu-El-Haija A, Fineman J, Connolly AJ, Murali P, Judge LM, Slavotinek AM
• Observation of an Unusual Upward-Going Cosmic-Ray-like Event in the Third Flight of ANITA.
  Physical review letters 2018 Gorham PW, Rotter B, Allison P, Banerjee O, Batten L, Beatty JJ, Bechtol K, Belov K, Besson DZ, Binns WR, Bugaev V, Cao P, Chen CC, Chen CH, Chen P, Clem JM, Connolly A, Cremonesi L, Dailey B, Deaconu…
• Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity.
  Nature communications 2017 Winters IP, Chiou SH, Paulk NK, McFarland CD, Lalgudi PV, Ma RK, Lisowski L, Connolly AJ, Petrov DA, Kay MA, Winslow MM
• Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics.
  Cell reports 2017 Kooreman NG, de Almeida PE, Stack JP, Nelakanti RV, Diecke S, Shao NY, Swijnenburg RJ, Sanchez-Freire V, Matsa E, Liu C, Connolly AJ, Hamming JF, Quax PHA, Brehm MA, Greiner DL, Shultz LD, Wu JC
• Early Development of Right Ventricular Ischemic Lesions in a Novel Large Animal Model of Acute Right Heart Failure in Chronic Thromboembolic Pulmonary Hypertension.
  Journal of cardiac failure 2017 Boulate D, Arthur Ataam J, Connolly AJ, Giraldeau G, Amsallem M, Decante B, Lamrani L, Fadel E, Dorfmuller P, Perros F, Haddad F, Mercier O
• Brief Report: External Beam Radiation Therapy for the Treatment of Human Pluripotent Stem Cell-Derived Teratomas.
  Stem cells (Dayton, Ohio) 2017 Lee AS, Tang C, Hong WX, Park S, Bazalova-Carter M, Nelson G, Sanchez-Freire V, Bakerman I, Zhang W, Neofytou E, Connolly AJ, Chan CK, Graves EE, Weissman IL, Nguyen PK, Wu JC
• PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity.
  Nature 2017 Gordon SR, Maute RL, Dulken BW, Hutter G, George BM, McCracken MN, Gupta R, Tsai JM, Sinha R, Corey D, Ring AM, Connolly AJ, Weissman IL
• Long-term miR-29b suppression reduces aneurysm formation in a Marfan mouse model.
  Physiological reports 2017 Okamura H, Emrich F, Trojan J, Chiu P, Dalal AR, Arakawa M, Sato T, Penov K, Koyano T, Pedroza A, Connolly AJ, Rabinovitch M, Alvira C, Fischbein MP
• Eosinophil-Rich Acute Febrile Neutrophilic Dermatosis in a Patient With Enteropathy-Associated T-cell Lymphoma, Type 1.
  The American Journal of dermatopathology 2016 Soon CW, Kirsch IR, Connolly AJ, Kwong BY, Kim J
• Characteristics of Four Upward-Pointing Cosmic-Ray-like Events Observed with ANITA.
  Physical review letters 2016 Gorham PW, Nam J, Romero-Wolf A, Hoover S, Allison P, Banerjee O, Beatty JJ, Belov K, Besson DZ, Binns WR, Bugaev V, Cao P, Chen C, Chen P, Clem JM, Connolly A, Dailey B, Deaconu C, Cremonesi L, …
• CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis.
  Nature 2016 Kojima Y, Volkmer JP, McKenna K, Civelek M, Lusis AJ, Miller CL, Direnzo D, Nanda V, Ye J, Connolly AJ, Schadt EE, Quertermous T, Betancur P, Maegdefessel L, Matic LP, Hedin U, Weissman IL, Leeper NJ
• Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility.
  Cell 2016 Denny SK, Yang D, Chuang CH, Brady JJ, Lim JS, Grüner BM, Chiou SH, Schep AN, Baral J, Hamard C, Antoine M, Wislez M, Kong CS, Connolly AJ, Park KS, Sage J, Greenleaf WJ, Winslow MM
• An Arntl2-Driven Secretome Enables Lung Adenocarcinoma Metastatic Self-Sufficiency.
  Cancer cell 2016 Brady JJ, Chuang CH, Greenside PG, Rogers ZN, Murray CW, Caswell DR, Hartmann U, Connolly AJ, Sweet-Cordero EA, Kundaje A, Winslow MM
• Comparison of Magnetic Resonance Imaging and Serum Biomarkers for Detection of Human Pluripotent Stem Cell-Derived Teratomas.
  Stem cell reports 2016 Riegler J, Ebert A, Qin X, Shen Q, Wang M, Ameen M, Kodo K, Ong SG, Lee WH, Lee G, Neofytou E, Gold JD, Connolly AJ, Wu JC
• CDKN2B Regulates TGFβ Signaling and Smooth Muscle Cell Investment of Hypoxic Neovessels.
  Circulation research 2015 Nanda V, Downing KP, Ye J, Xiao S, Kojima Y, Spin JM, DiRenzo D, Nead KT, Connolly AJ, Dandona S, Perisic L, Hedin U, Maegdefessel L, Dalman J, Guo L, Zhao X, Kolodgie FD, Virmani R, Davis HR, Leeper …
• Mitral Stenosis and Aortic Atresia--A Risk Factor for Mortality After the Modified Norwood Operation in Hypoplastic Left Heart Syndrome.
  The Annals of thoracic surgery 2015 Siehr SL, Maeda K, Connolly AA, Tacy TA, Reddy VM, Hanley FL, Perry SB, Wright GE
• Human Engineered Heart Muscles Engraft and Survive Long Term in a Rodent Myocardial Infarction Model.
  Circulation research 2015 Riegler J, Tiburcy M, Ebert A, Tzatzalos E, Raaz U, Abilez OJ, Shen Q, Kooreman NG, Neofytou E, Chen VC, Wang M, Meyer T, Tsao PS, Connolly AJ, Couture LA, Gold JD, Zimmermann WH, Wu JC
• Optical Coherence Tomography of Pulmonary Arterial Walls in Humans and Pigs (Sus scrofa domesticus).
  Comparative medicine 2015 Brunner NW, Zamanian RT, Ikeno F, Mitsutake Y, Connolly AJ, Shuffle E, Yuan K, Orcholski M, Lyons J, de Jesus Perez VA
• Enhanced caspase activity contributes to aortic wall remodeling and early aneurysm development in a murine model of Marfan syndrome.
  Arteriosclerosis, thrombosis, and vascular biology 2014 Emrich FC, Okamura H, Dalal AR, Penov K, Merk DR, Raaz U, Hennigs JK, Chin JT, Miller MO, Pedroza AJ, Craig JK, Koyano TK, Blankenberg FG, Connolly AJ, Mohr FW, Alvira CM, Rabinovitch M, Fischbein MP
• Clonal analysis reveals nerve-dependent and independent roles on mammalian hind limb tissue maintenance and regeneration.
  Proceedings of the National Academy of Sciences of the United States of America 2014 Rinkevich Y, Montoro DT, Muhonen E, Walmsley GG, Lo D, Hasegawa M, Januszyk M, Connolly AJ, Weissman IL, Longaker MT
• Assessment of elastin deficit in a Marfan mouse aneurysm model using an elastin-specific magnetic resonance imaging contrast agent.
  Circulation. Cardiovascular imaging 2014 Okamura H, Pisani LJ, Dalal AR, Emrich F, Dake BA, Arakawa M, Onthank DC, Cesati RR, Robinson SP, Milanesi M, Kotek G, Smit H, Connolly AJ, Adachi H, McConnell MV, Fischbein MP
• Obligate progression precedes lung adenocarcinoma dissemination.
  Cancer discovery 2014 Caswell DR, Chuang CH, Yang D, Chiou SH, Cheemalavagu S, Kim-Kiselak C, Connolly A, Winslow MM
• Histological characteristics of myocardial bridge with an ultrasonic echolucent band. Comparison between intravascular ultrasound and histology.
  Circulation journal : official journal of the Japanese Circulation Society 2013 Yamada R, Turcott RG, Connolly AJ, Ikeno F, McConnell MV, Schnittger I, Fitzgerald PJ, Honda Y
• Femtosecond plasma mediated laser ablation has advantages over mechanical osteotomy of cranial bone.
  Lasers in surgery and medicine 2012 Lo DD, Mackanos MA, Chung MT, Hyun JS, Montoro DT, Grova M, Liu C, Wang J, Palanker D, Connolly AJ, Longaker MT, Contag CH, Wan DC
• In vivo directed differentiation of pluripotent stem cells for skeletal regeneration.
  Proceedings of the National Academy of Sciences of the United States of America 2012 Levi B, Hyun JS, Montoro DT, Lo DD, Chan CK, Hu S, Sun N, Lee M, Grova M, Connolly AJ, Wu JC, Gurtner GC, Weissman IL, Wan DC, Longaker MT
• Atherosclerosis causing recurrent catastrophic aortopulmonary shunt dehiscence in a patient with Alagille syndrome.
  Pediatric cardiology 2012 May L, Hanley FL, Connolly AJ, Reddy S
• Microfluidic single-cell analysis shows that porcine induced pluripotent stem cell-derived endothelial cells improve myocardial function by paracrine activation.
  Circulation research 2012 Gu M, Nguyen PK, Lee AS, Xu D, Hu S, Plews JR, Han L, Huber BC, Lee WH, Gong Y, de Almeida PE, Lyons J, Ikeno F, Pacharinsak C, Connolly AJ, Gambhir SS, Robbins RC, Longaker MT, Wu JC
• A novel epidermal growth factor receptor variant lacking multiple domains directly activates transcription and is overexpressed in tumors.
  Oncogene 2011 Piccione EC, Lieu TJ, Gentile CF, Williams TR, Connolly AJ, Godwin AK, Koong AC, Wong AJ
• Cardiac pressure overload hypertrophy is differentially regulated by β-adrenergic receptor subtypes.
  American journal of physiology. Heart and circulatory physiology 2011 Zhao M, Fajardo G, Urashima T, Spin JM, Poorfarahani S, Rajagopalan V, Huynh D, Connolly A, Quertermous T, Bernstein D
• Pretreatment with angiotensin-converting enzyme inhibitor improves doxorubicin-induced cardiomyopathy via preservation of mitochondrial function.
  The Journal of thoracic and cardiovascular surgery 2010 Hiona A, Lee AS, Nagendran J, Xie X, Connolly AJ, Robbins RC, Wu JC
• Influences of aortic motion and curvature on vessel expansion in murine experimental aneurysms.
  Arteriosclerosis, thrombosis, and vascular biology 2010 Goergen CJ, Azuma J, Barr KN, Magdefessel L, Kallop DY, Gogineni A, Grewall A, Weimer RM, Connolly AJ, Dalman RL, Taylor CA, Tsao PS, Greve JM
• Observation of ultrahigh-energy cosmic rays with the ANITA balloon-borne radio interferometer.
  Physical review letters 2010 Hoover S, Nam J, Gorham PW, Grashorn E, Allison P, Barwick SW, Beatty JJ, Belov K, Besson DZ, Binns WR, Chen C, Chen P, Clem JM, Connolly A, Dowkontt PF, DuVernois MA, Field RC, Goldstein D, Vieregg …
• In vivo quantification of murine aortic cyclic strain, motion, and curvature: implications for abdominal aortic aneurysm growth.
  Journal of magnetic resonance imaging : JMRI 2010 Goergen CJ, Barr KN, Huynh DT, Eastham-Anderson JR, Choi G, Hedehus M, Dalman RL, Connolly AJ, Taylor CA, Tsao PS, Greve JM
• The role of recipient mast cells in acute and chronic cardiac allograft rejection in C57BL/6-KitW-sh/W-sh mice.
  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2009 Itoh S, Nakae S, Velotta JB, Kosuge H, Connolly A, Tsai M, Adachi H, Galli SJ, Robbins RC, Fischbein MP
• Effects of cell number on teratoma formation by human embryonic stem cells.
  Cell cycle (Georgetown, Tex.) 2009 Lee AS, Tang C, Cao F, Xie X, van der Bogt K, Hwang A, Connolly AJ, Robbins RC, Wu JC
• New limits on the ultrahigh energy cosmic neutrino flux from the ANITA experiment.
  Physical review letters 2009 Gorham PW, Allison P, Barwick SW, Beatty JJ, Besson DZ, Binns WR, Chen C, Chen P, Clem JM, Connolly A, Dowkontt PF, Duvernois MA, Field RC, Goldstein D, Goodhue A, Hast C, Hebert CL, Hoover S, Israel …
• Imaging gene expression in human mesenchymal stem cells: from small to large animals.
  Radiology 2009 Willmann JK, Paulmurugan R, Rodriguez-Porcel M, Stein W, Brinton TJ, Connolly AJ, Nielsen CH, Lutz AM, Lyons J, Ikeno F, Suzuki Y, Rosenberg J, Chen IY, Wu JC, Yeung AC, Yock P, Robbins RC, Gambhir SS
• In vivo imaging of embryonic stem cells reveals patterns of survival and immune rejection following transplantation.
  Stem cells and development 2008 Swijnenburg RJ, Schrepfer S, Cao F, Pearl JI, Xie X, Connolly AJ, Robbins RC, Wu JC
• Personality disorders in homeless drop-in center clients.
  Journal of personality disorders 2008 Connolly AJ, Cobb-Richardson P, Ball SA
• Integrin alphavbeta3-targeted radioimmunotherapy of glioblastoma multiforme.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Veeravagu A, Liu Z, Niu G, Chen K, Jia B, Cai W, Jin C, Hsu AR, Connolly AJ, Tse V, Wang F, Chen X
• Insulin resistance is associated with a modest increase in inflammation in subcutaneous adipose tissue of moderately obese women.
  Diabetologia 2008 McLaughlin T, Deng A, Gonzales O, Aillaud M, Yee G, Lamendola C, Abbasi F, Connolly AJ, Sherman A, Cushman SW, Reaven G, Tsao PS
• Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts.
  Proceedings of the National Academy of Sciences of the United States of America 2008 Swijnenburg RJ, Schrepfer S, Govaert JA, Cao F, Ransohoff K, Sheikh AY, Haddad M, Connolly AJ, Davis MM, Robbins RC, Wu JC
• Multimodal evaluation of in vivo magnetic resonance imaging of myocardial restoration by mouse embryonic stem cells.
  The Journal of thoracic and cardiovascular surgery 2008 Hendry SL, van der Bogt KE, Sheikh AY, Arai T, Dylla SJ, Drukker M, McConnell MV, Kutschka I, Hoyt G, Cao F, Weissman IL, Connolly AJ, Pelletier MP, Wu JC, Robbins RC, Yang PC
• Introducing the first polymer-free leflunomide eluting stent.
  Atherosclerosis 2008 Deuse T, Erben RG, Ikeno F, Behnisch B, Boeger R, Connolly AJ, Reichenspurner H, Bergow C, Pelletier MP, Robbins RC, Schrepfer S
• Comparison of reporter gene and iron particle labeling for tracking fate of human embryonic stem cells and differentiated endothelial cells in living subjects.
  Stem cells (Dayton, Ohio) 2008 Li Z, Suzuki Y, Huang M, Cao F, Xie X, Connolly AJ, Yang PC, Wu JC
• Spatial and temporal kinetics of teratoma formation from murine embryonic stem cell transplantation.
  Stem cells and development 2007 Cao F, van der Bogt KE, Sadrzadeh A, Xie X, Sheikh AY, Wang H, Connolly AJ, Robbins RC, Wu JC
• Observations of the Askaryan effect in ice.
  Physical review letters 2007 Gorham PW, Barwick SW, Beatty JJ, Besson DZ, Binns WR, Chen C, Chen P, Clem JM, Connolly A, Dowkontt PF, DuVernois MA, Field RC, Goldstein D, Goodhue A, Hast C, Hebert CL, Hoover S, Israel MH, …
• In vivo genetic profiling and cellular localization of apelin reveals a hypoxia-sensitive, endothelial-centered pathway activated in ischemic heart failure.
  American journal of physiology. Heart and circulatory physiology 2007 Sheikh AY, Chun HJ, Glassford AJ, Kundu RK, Kutschka I, Ardigo D, Hendry SL, Wagner RA, Chen MM, Ali ZA, Yue P, Huynh DT, Connolly AJ, Pelletier MP, Tsao PS, Robbins RC, Quertermous T
• Genetic modification of embryonic stem cells with VEGF enhances cell survival and improves cardiac function.
  Cloning and stem cells 2007 Xie X, Cao F, Sheikh AY, Li Z, Connolly AJ, Pei X, Li RK, Robbins RC, Wu JC
• Molecular imaging of embryonic stem cell misbehavior and suicide gene ablation.
  Cloning and stem cells 2007 Cao F, Drukker M, Lin S, Sheikh AY, Xie X, Li Z, Connolly AJ, Weissman IL, Wu JC
• Network analysis of human in-stent restenosis.
  Circulation 2006 Ashley EA, Ferrara R, King JY, Vailaya A, Kuchinsky A, He X, Byers B, Gerckens U, Oblin S, Tsalenko A, Soito A, Spin JM, Tabibiazar R, Connolly AJ, Simpson JB, Grube E, Quertermous T
• Proteomic analysis of reporter genes for molecular imaging of transplanted embryonic stem cells.
  Proteomics 2006 Wu JC, Cao F, Dutta S, Xie X, Kim E, Chungfat N, Gambhir S, Mathewson S, Connolly AJ, Brown M, Wang EW
• Adenoviral human BCL-2 transgene expression attenuates early donor cell death after cardiomyoblast transplantation into ischemic rat hearts.
  Circulation 2006 Kutschka I, Kofidis T, Chen IY, von Degenfeld G, Zwierzchoniewska M, Hoyt G, Arai T, Lebl DR, Hendry SL, Sheikh AY, Cooke DT, Connolly A, Blau HM, Gambhir SS, Robbins RC
• In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery.
  Circulation 2006 Cao F, Lin S, Xie X, Ray P, Patel M, Zhang X, Drukker M, Dylla SJ, Connolly AJ, Chen X, Weissman IL, Gambhir SS, Wu JC
• Pathway analysis of coronary atherosclerosis.
  Physiological genomics 2005 King JY, Ferrara R, Tabibiazar R, Spin JM, Chen MM, Kuchinsky A, Vailaya A, Kincaid R, Tsalenko A, Deng DX, Connolly A, Zhang P, Yang E, Watt C, Yakhini Z, Ben-Dor A, Adler A, Bruhn L, Tsao P, …
• Heterogeneity of endothelial cells from different organ sites in T-cell subset recruitment.
  The American journal of pathology 2003 Lim YC, Garcia-Cardena G, Allport JR, Zervoglos M, Connolly AJ, Gimbrone MA, Luscinskas FW
• Antibodies to protease-activated receptor 3 inhibit activation of mouse platelets by thrombin.
  Blood 1998 Ishihara H, Zeng D, Connolly AJ, Tam C, Coughlin SR
• Mice lacking the thrombin receptor, PAR1, have normal skin wound healing.
  The American journal of pathology 1997 Connolly AJ, Suh DY, Hunt TK, Coughlin SR
• Protease-activated receptor 3 is a second thrombin receptor in humans.
  Nature 1997 Ishihara H, Connolly AJ, Zeng D, Kahn ML, Zheng YW, Timmons C, Tram T, Coughlin SR
• The cloned thrombin receptor is necessary and sufficient for activation of mitogen-activated protein kinase and mitogenesis in mouse lung fibroblasts. Loss of responses in fibroblasts from receptor knockout mice.
  The Journal of biological chemistry 1996 Trejo J, Connolly AJ, Coughlin SR
• Role of the thrombin receptor in development and evidence for a second receptor.
  Nature 1996 Connolly AJ, Ishihara H, Kahn ML, Farese RV, Coughlin SR
• Conserved structure and adjacent location of the thrombin receptor and protease-activated receptor 2 genes define a protease-activated receptor gene cluster.
  Molecular medicine (Cambridge, Mass.) 1996 Kahn M, Ishii K, Kuo WL, Piper M, Connolly A, Shi YP, Wu R, Lin CC, Coughlin SR
• Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2.
  The Biochemical journal 1996 Bohm SK, Kong W, Bromme D, Smeekens SP, Anderson DC, Connolly A, Kahn M, Nelken NA, Coughlin SR, Payan DG, Bunnett NW
• A genetic model for absent chylomicron formation: mice producing apolipoprotein B in the liver, but not in the intestine.
  The Journal of clinical investigation 1995 Young SG, Cham CM, Pitas RE, Burri BJ, Connolly A, Flynn L, Pappu AS, Wong JS, Hamilton RL, Farese RV
• Design and initial testing of an ultrasound-guided directional atherectomy device.
  American heart journal 1995 Fitzgerald PJ, Belef M, Connolly AJ, Sudhir K, Yock PG
• Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails.
  Proceedings of the National Academy of Sciences of the United States of America 1994 Charo IF, Myers SJ, Herman A, Franci C, Connolly AJ, Coughlin SR
• Potassium preserves endothelial function and enhances aortic compliance in Dahl rats.
  Hypertension (Dallas, Tex. : 1979) 1993 Sudhir K, Kurtz TW, Yock PG, Connolly AJ, Morris RC
• Intravascular ultrasound imaging of coronary arteries. Is three layers the norm?
  Circulation 1992 Fitzgerald PJ, St Goar FG, Connolly AJ, Pinto FJ, Billingham ME, Popp RL, Yock PG
• Fluid shear stress modulates cytosolic free calcium in vascular endothelial cells.
  The American journal of physiology 1992 Shen J, Luscinskas FW, Connolly A, Dewey CF, Gimbrone MA
• Myocardial infarction: assessment with an intravascular MR contrast medium. Work in progress.
  Radiology 1991 Saeed M, Wendland MF, Masui T, Connolly AJ, Derugin N, Brasch RC, Higgins CB
• Transmembrane distribution of gramicidin by tryptophan energy transfer.
  Biophysical journal 1986 Boni LT, Connolly AJ, Kleinfeld AM