An Cheng, PhD
Postdoctoral Scholar
Ophthalmology
School of Medicine

My work includes exploring novel therapeutic approaches and inhibitors to protect against memory loss and mitochondrial damage induced by neurodegenerative processes. I am honored to have received prestigious awards and fellowships, including the Tohoku University President's Award and The Uehara Memorial Foundation Fellowship. I hold a Ph.D. in Neuropharmacology from Tohoku University, Sendai, Japan, and a B.S. in Pharmaceutical Science from China Pharmaceutical University, Nanjing, China.

• Feasibility and considerations of epsin2 as a candidate target for multiple system atrophy treatment.
  Expert opinion on therapeutic targets 2023 Cheng A, Cai B, Fukunaga K, Sasaki T, Lakkaraju A
• Editorial: Myelin in white mater function and related diseases.
  Frontiers in molecular neuroscience 2023 Tian Z, Cheng A
• Amelioration of Nicotine-Induced Conditioned Place Preference Behaviors in Mice by an FABP3 Inhibitor.
  International journal of molecular sciences 2023 Jia W, Kawahata I, Cheng A, Sasaki T, Sasaoka T, Fukunaga K
• Novel FABP3 ligand, HY-11-9, ameliorates neuropathological deficits in MPTP-induced Parkinsonism in mice.
  Journal of pharmacological sciences 2023 Wang H, Fukunaga K, Cheng A, Wang Y, Arimura N, Yoshino H, Sasaki T, Kawahata I
• α-Synuclein decoy peptide protects mice against α-synuclein-induced memory loss.
  CNS neuroscience & therapeutics 2023 Guo Q, Kawahata I, Jia W, Wang H, Cheng A, Yabuki Y, Shioda N, Fukunaga K
• Fatty acid-binding proteins 3 and 5 are involved in the initiation of mitochondrial damage in ischemic neurons.
  Redox biology 2022 Guo Q, Kawahata I, Cheng A, Wang H, Jia W, Yoshino H, Fukunaga K
• Fatty Acid-Binding Proteins: Their Roles in Ischemic Stroke and Potential as Drug Targets.
  International journal of molecular sciences 2022 Guo Q, Kawahata I, Cheng A, Jia W, Wang H, Fukunaga K
• [Role of fatty acid-binding protein 7 and novel therapeutic approach in synucleinopathies].
  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 2022 Cheng A, Fukunaga K
• Hydroxyl-Directed Ruthenium-Catalyzed peri-Selective C-H Acylmethylation and Annulation of Naphthols with Sulfoxonium Ylides.
  Organic letters 2021 Ma W, Tan Y, Wang Y, Li Z, Li Z, Gu L, Mei R, Cheng A
• Impact of Fatty Acid-Binding Proteins in α-Synuclein-Induced Mitochondrial Injury in Synucleinopathy.
  Biomedicines 2021 Cheng A, Jia W, Kawahata I, Fukunaga K
• The Role of CaMKII and ERK Signaling in Addiction.
  International journal of molecular sciences 2021 Jia W, Kawahata I, Cheng A, Fukunaga K
• Ligand Bound Fatty Acid Binding Protein 7 (FABP7) Drives Melanoma Cell Proliferation Via Modulation of Wnt/β-Catenin Signaling.
  Pharmaceutical research 2021 Umaru BA, Kagawa Y, Shil SK, Arakawa N, Pan Y, Miyazaki H, Kobayashi S, Yang S, Cheng A, Wang Y, Shinoda Y, Kiniwa Y, Okuyama R, Fukunaga K, Owada Y
• Epidermal Fatty Acid-Binding Protein 5 (FABP5) Involvement in Alpha-Synuclein-Induced Mitochondrial Injury under Oxidative Stress.
  Biomedicines 2021 Wang Y, Shinoda Y, Cheng A, Kawahata I, Fukunaga K
• Single Administration of the T-Type Calcium Channel Enhancer SAK3 Reduces Oxidative Stress and Improves Cognition in Olfactory Bulbectomized Mice.
  International journal of molecular sciences 2021 Yuan D, Cheng A, Kawahata I, Izumi H, Xu J, Fukunaga K
• Impaired Acquisition of Nicotine-Induced Conditioned Place Preference in Fatty Acid-Binding Protein 3 Null Mice.
  Molecular neurobiology 2021 Jia W, Wilar G, Kawahata I, Cheng A, Fukunaga K
• Inhibition of MPTP-induced α-synuclein oligomerization by fatty acid-binding protein 3 ligand in MPTP-treated mice.
  Neuropharmacology 2019 Matsuo K, Cheng A, Yabuki Y, Takahata I, Miyachi H, Fukunaga K
• Development of FABP3 ligands that inhibit arachidonic acid-induced α-synuclein oligomerization.
  Brain research 2018 Cheng A, Shinoda Y, Yamamoto T, Miyachi H, Fukunaga K