Amy Gryshuk, PhD
Associate Director
Innovation Ventures
Chancellor/EVC/FAS

Publications (18)

Top publication keywords:
PorphyrinsDrug RepositioningMice, Inbred C3HFluorineChlorophyllPhotosensitizing AgentsPhotochemotherapySpectrum Analysis, RamanBacteriochlorophyll ADrug Screening Assays, AntitumorImidesElectronic Health RecordsAmyotrophic Lateral SclerosisPrecision MedicineBreath Tests

• Identification of drug repurposing candidates for amyotrophic lateral sclerosis using electronic health records: a retrospective cohort study.
  The Lancet. Digital health 2026 Reimer RJ, Soper B, Wilson JL, Goncalves AR, Cadena J, Suarez P, Gryshuk AL, Osborne TF, Grimes KV, Ray P
• An electronic health record cohort of Veterans with amyotrophic lateral sclerosis.
  Amyotrophic lateral sclerosis & frontotemporal degeneration 2023 Reimer RJ, Goncalves A, Soper B, Cadena J, Wilson JL, Gryshuk AL, Suarez P, Osborne TF, Grimes KV, Ray P
• COVID-19 outcomes in patients with cancer: Findings from the University of California health system database.
  Cancer medicine 2022 Kwon DH, Cadena J, Nguyen S, Chan KHR, Soper B, Gryshuk AL, Hong JC, Ray P, Huang FW
• Digital twins for predictive oncology will be a paradigm shift for precision cancer care.
  Nature medicine 2021 Hernandez-Boussard T, Macklin P, Greenspan EJ, Gryshuk AL, Stahlberg E, Syeda-Mahmood T, Shmulevich I
• AI Meets Exascale Computing: Advancing Cancer Research With Large-Scale High Performance Computing.
  Frontiers in oncology 2019 Bhattacharya T, Brettin T, Doroshow JH, Evrard YA, Greenspan EJ, Gryshuk AL, Hoang TT, Lauzon CBV, Nissley D, Penberthy L, Stahlberg E, Stevens R, Streitz F, Tourassi G, Xia F, Zaki G

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• Investigating drug induced changes in single, living lymphocytes based on Raman micro-spectroscopy.
  The Analyst 2014 Schie IW, Alber L, Gryshuk AL, Chan JW
• Emerging topics and new developments in the field: the 2012 International Breath Analysis meeting.
  Journal of breath research 2013 Davis CE, Epton M, Frank M, Gryshuk A, Kenyon NJ
• Cell-phone-based platform for biomedical device development and education applications.
  PloS one 2011 Smith ZJ, Chu K, Espenson AR, Rahimzadeh M, Gryshuk A, Molinaro M, Dwyre DM, Lane S, Matthews D, Wachsmann-Hogiu S
• Structure-activity relationship among purpurinimides and bacteriopurpurinimides: trifluoromethyl substituent enhanced the photosensitizing efficacy.
  Journal of medicinal chemistry 2007 Gryshuk A, Chen Y, Goswami LN, Pandey S, Missert JR, Ohulchanskyy T, Potter W, Prasad PN, Oseroff A, Pandey RK
• Nature: a rich source for developing multifunctional agents. Tumor-imaging and photodynamic therapy.
  Lasers in surgery and medicine 2006 Pandey RK, Goswami LN, Chen Y, Gryshuk A, Missert JR, Oseroff A, Dougherty TJ
• In vivo stability and photodynamic efficacy of fluorinated bacteriopurpurinimides derived from bacteriochlorophyll-a.
  Journal of medicinal chemistry 2006 Gryshuk AL, Chen Y, Potter W, Ohulchansky T, Oseroff A, Pandey RK
• Multimodality agents for tumor imaging (PET, fluorescence) and photodynamic therapy. A possible "see and treat" approach.
  Journal of medicinal chemistry 2005 Pandey SK, Gryshuk AL, Sajjad M, Zheng X, Chen Y, Abouzeid MM, Morgan J, Charamisinau I, Nabi HA, Oseroff A, Pandey RK
• A novel approach to a bifunctional photosensitizer for tumor imaging and phototherapy.
  Bioconjugate chemistry 2005 Chen Y, Gryshuk A, Achilefu S, Ohulchansky T, Potter W, Zhong T, Morgan J, Chance B, Prasad PN, Henderson BW, Oseroff A, Pandey RK
• Methyl pyropheophorbide-a analogues: potential fluorescent probes for the peripheral-type benzodiazepine receptor. Effect of central metal in photosensitizing efficacy.
  Journal of medicinal chemistry 2005 Chen Y, Zheng X, Dobhal MP, Gryshuk A, Morgan J, Dougherty TJ, Oseroff A, Pandey RK
• Synthesis and photosensitizing efficacy of isomerically pure bacteriopurpurinimides.
  Journal of medicinal chemistry 2004 Chen Y, Sumlin A, Morgan J, Gryshuk A, Oseroff A, Henderson BW, Dougherty TJ, Pandey RK
• Structural modifications of plumieride isolated from Plumeria bicolor and the effect of these modifications on in vitro anticancer activity.
  The Journal of organic chemistry 2004 Dobhal MP, Li G, Gryshuk A, Graham A, Bhatanager AK, Khaja SD, Joshi YC, Sharma MC, Oseroff A, Pandey RK
• Functionalization of OEP-based benzochlorins to develop carbohydrate-conjugated photosensitizers. Attempt to target beta-galactoside-recognized proteins.
  The Journal of organic chemistry 2004 Li G, Pandey SK, Graham A, Dobhal MP, Mehta R, Chen Y, Gryshuk A, Rittenhouse-Olson K, Oseroff A, Pandey RK
• A first comparative study of purpurinimide-based fluorinated vs. nonfluorinated photosensitizers for photodynamic therapy.
  Photochemistry and photobiology 2002 Gryshuk AL, Graham A, Pandey SK, Potter WR, Missert JR, Oseroff A, Dougherty TJ, Pandey RK