Amy Berger, MD, PhD
Attending Physician
Medicine
School of Medicine

I am a physician-scientist who enjoys working at the intersection of multiple areas of medicine and science. I am interested in physician-scientist training, the application of pathophysiology to clinical reasoning, and the translation of cutting edge technologies to the clinic.

Education & Training

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• Fellowship Academic Hospital Medicine University of California, San Francisco 2017
• Fellowship Clinical and Translational Science University of California, San Francisco 2017
• Residency Internal Medicine University of California, San Francisco 2016
• MD, PhD PhD in Neuroscience University of California, San Francisco 2012
• BS Biological Sciences Stanford University 2002

Interests

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• physician-scientist education
• molecular medicine
• precision medicine
• translational research

Publications (13)

Top publication keywords:
Attitude of Health PersonnelMorphineDrug ToleranceDrug DesignMolecular MedicinePhysiciansAnalgesics, OpioidCompulsive BehaviorMorphine DependenceReceptors, Opioid, muStudents, MedicalMeningitis, AsepticComplement Factor IMetagenomicsResearch

• Cell-Type Specificity of Mosaic Chromosome 1q Gain Resolved by snRNA-seq in a Case of Epilepsy With Hyaline Protoplasmic Astrocytopathy.
  Neurology. Genetics 2024 Leng K, Cadwell CR, Devine WP, Tihan T, Qi Z, Singhal NS, Glenn OA, Kamiya S, Wiita AP, Berger AC, Shieh JT, Titus EW, Paredes MF, Upadhyay V
• Alterations in Lysosomal, Glial and Neurodegenerative Biomarkers in Patients with Sporadic and Genetic Forms of Frontotemporal Dementia.
  bioRxiv : the preprint server for biology 2024 Hsiao-Nakamoto J, Chiu CL, VandeVrede L, Ravi R, Vandenberg B, De Groot J, Tsogtbaatar B, Fang M, Auger P, Gould NS, Marchioni F, Powers CA, Davis SS, Suh JH, Alkabsh J, Heuer HW, Lago AL, Scearce-…
• Cell type specificity of mosaic chromosome 1q gain resolved by snRNA-seq in a case of epilepsy with hyaline protoplasmic astrocytopathy.
  bioRxiv : the preprint server for biology 2024 Leng K, Cadwell CR, Patrick Devine W, Tihan T, Qi Z, Singhal N, Glenn O, Kamiya S, Wiita A, Berger A, Shieh JT, Titus EW, Paredes MF, Upadhyay V
• Complement Factor I Gene Variant as a Treatable Cause of Recurrent Aseptic Neutrophilic Meningitis: A Case Report.
  Neurology(R) neuroimmunology & neuroinflammation 2023 Rolfes M, Harroud A, Zorn KC, Tubati A, Omura C, Kurtz K, Matloubian M, Berger A, Chiu CY, Wilson MR, Ramachandran PS
• Implementation of Clinical Practice Guidelines for Hospitalized Patients With COVID-19 in Academic Medical Centers.
  JAMA network open 2022 Berger AC, Simchoni N, Auerbach A, Brode WM, Kuperman E, Raffel K, Kubey A, HOMERuN COVID-19 Collaborative Group

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• Rapid pathogen detection by metagenomic next-generation sequencing of infected body fluids.
  Nature medicine 2020 Gu W, Deng X, Lee M, Sucu YD, Arevalo S, Stryke D, Federman S, Gopez A, Reyes K, Zorn K, Sample H, Yu G, Ishpuniani G, Briggs B, Chow ED, Berger A, Wilson MR, Wang C, Hsu E, Miller S, DeRisi JL, Chiu …
• Rosai-Dorfman as a clinical mimicker of relapsing polychondritis
  Journal of the American Academy of Dermatology Case Reports 2020 Song E, Pincus L, Berger A, Butrymowicz A, Haemel A.
• The Molecular Medicine Investigation Unit: Linking Patient Care and Scientific Inquiry in Physician-Scientist Training.
  Journal of graduate medical education 2020 Berger A, Matloubian M, Shah NP, Wachter RM, DeRisi JL, Anderson M
• Elastase 3B mutation links to familial pancreatitis with diabetes and pancreatic adenocarcinoma.
  The Journal of clinical investigation 2019 Moore PC, Cortez JT, Chamberlain CE, Alba D, Berger AC, Quandt Z, Chan A, Cheng MH, Bautista JL, Peng J, German MS, Anderson MS, Oakes SA
• Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis.
  The New England journal of medicine 2019 Wilson MR, Sample HA, Zorn KC, Arevalo S, Yu G, Neuhaus J, Federman S, Stryke D, Briggs B, Langelier C, Berger A, Douglas V, Josephson SA, Chow FC, Fulton BD, DeRisi JL, Gelfand JM, Naccache SN, …
• Morphine-induced mu opioid receptor trafficking enhances reward yet prevents compulsive drug use.
  EMBO molecular medicine 2011 Berger AC, Whistler JL
• How to design an opioid drug that causes reduced tolerance and dependence.
  Annals of neurology 2010 Berger AC, Whistler JL
• Morphine-induced receptor endocytosis in a novel knockin mouse reduces tolerance and dependence.
  Current biology : CB 2008 Kim JA, Bartlett S, He L, Nielsen CK, Chang AM, Kharazia V, Waldhoer M, Ou CJ, Taylor S, Ferwerda M, Cado D, Whistler JL