Allan Flach, MD, PharmD
Professor
Ophthalmology
School of Medicine

Education & Training

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• M.D. Medicine University of California, San Francisco 1971
• Pharm.D. Pharmacy University of California, San Francisco 1967
• Residency University of California, San Francisco

Publications (73)

Top publication keywords:
TromethamineEye DiseasesOphthalmic SolutionsOphthalmologyDiclofenacCataractCorneal DiseasesMacular EdemaAdministration, TopicalKetorolac TromethamineCorneaCataract ExtractionHydroxychloroquineAnti-Inflammatory Agents, Non-SteroidalTolmetin

• Cataractogenic potential of quetiapine versus risperidone in the long-term treatment of patients with schizophrenia or schizoaffective disorder: a randomized, open-label, ophthalmologist-masked, flexible-dose, non-inferiority trial.
  Journal of psychopharmacology (Oxford, England) 2014 Laties AM, Flach AJ, Baldycheva I, Rak I, Earley W, Pathak S
• Amsler grids for chloroquine toxicity.
  Ophthalmology 2011 Flach AJ
• Nonsteroidal anti-inflammatory drugs in ophthalmology.
  Survey of ophthalmology 2010 Kim SJ, Flach AJ, Jampol LM
• Intraoperative floppy iris syndrome: pathophysiology, prevention, and treatment.
  Transactions of the American Ophthalmological Society 2009 Flach AJ
• Proposed mandate for instructions and labeling regarding the use of eye drops.
  Archives of ophthalmology (Chicago, Ill. : 1960) 2009 Flach AJ

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• Debunking myths in physician-industry conflicts of interest.
  American journal of ophthalmology 2009 Flach AJ
• The importance of eyelid closure and nasolacrimal occlusion following the ocular instillation of topical glaucoma medications, and the need for the universal inclusion of one of these techniques in all patient treatments and clinical studies.
  Transactions of the American Ophthalmological Society 2008 Flach AJ
• Improving the risk-benefit relationship and informed consent for patients treated with hydroxychloroquine.
  Transactions of the American Ophthalmological Society 2007 Flach AJ
• Misuse and abuse of topically applied nonsteroidal anti-inflammatory drugs.
  Cornea 2006 Flach AJ
• Choroidal detachment following the use of tamsulosin (Flomax).
  American journal of ophthalmology 2006 Shapiro BL, Petrovic V, Lee SE, Flach A, McCaffery S, O'Brien JM
• Comparison of ketorolac tromethamine, diclofenac sodium, and loteprednol etabonate in an animal model of ocular inflammation.
  Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2006 Waterbury LD, Flach AJ
• Efficacy of low concentrations of ketorolac tromethamine in animal models of ocular inflammation.
  Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2004 Waterbury LD, Flach AJ
• Does medical treatment influence the success of trabeculectomy?
  Transactions of the American Ophthalmological Society 2004 Flach AJ
• Delta-9-tetrahydrocannabinol (THC) in the treatment of end-stage open-angle glaucoma.
  Transactions of the American Ophthalmological Society 2002 Flach AJ
• Additional factors linking corneal melting to topical nonsteroidal anti-inflammatory drugs.
  Archives of ophthalmology (Chicago, Ill. : 1960) 2001 Flach A
• Corneal melts associated with topically applied nonsteroidal anti-inflammatory drugs.
  Transactions of the American Ophthalmological Society 2001 Flach AJ
• Topically applied nonsteroidal anti-inflammatory drugs and corneal problems: an interim review and comment.
  Ophthalmology 2000 Flach A
• Incidence of postoperative posterior capsular opacification following treatment with diclofenac 0.1% and ketorolac 0.5% ophthalmic solutions: 3-year randomized, double-masked, prospective clinical investigation.
  Transactions of the American Ophthalmological Society 2000 Flach AJ, Dolan BJ
• Comparative effects of ketorolac 0.5% or diclofenac 0.1% ophthalmic solutions on inflammation after cataract surgery.
  Ophthalmology 1998 Flach AJ, Dolan BJ, Donahue ME, Faktorovich EG, Gonzalez GA
• The incidence, pathogenesis and treatment of cystoid macular edema following cataract surgery.
  Transactions of the American Ophthalmological Society 1998 Flach AJ
• Acetazolamide treatment of CME in patients with uveitis.
  Ophthalmology 1996 Flach A
• Ocular pharmacology and toxicology.
  Ophthalmology 1996 Flach AJ
• Topical nonsteroidal antiinflammatory drugs for ophthalmic use.
  International ophthalmology clinics 1996 Flach AJ
• Stevens-Johnson syndrome associated with methazolamide treatment reported in two Japanese-American women.
  Ophthalmology 1995 Flach AJ, Smith RE, Fraunfelder FT
• Efficacy of apraclonidine ophthalmic solution (iopidine) in presumed silicon oil-induced glaucoma and primary open-angle glaucoma.
  Survey of ophthalmology 1995 Flach AJ
• Pet flea and tick collar-induced anisocoria.
  Archives of ophthalmology (Chicago, Ill. : 1960) 1994 Flach AJ, Donahue ME
• Systemic toxicity. Associated with topical ophthalmic medications.
  The Journal of the Florida Medical Association 1994 Flach AJ
• Clear evidence that long-term, low-dose tamoxifen treatment can induce ocular toxicity: a prospective study of 63 patients.
  Survey of ophthalmology 1994 Flach AJ
• Nonsteroidal anti-inflammatory drugs in ophthalmology.
  International ophthalmology clinics 1993 Flach AJ
• Progression of amiodarone induced cataracts.
  Documenta ophthalmologica. Advances in ophthalmology 1993 Flach AJ, Dolan BJ
• Cyclo-oxygenase inhibitors in ophthalmology.
  Survey of ophthalmology 1992 Flach AJ
• Effects of topically applied 2% epinephrine and 0.1% dipivalyl epinephrine on the adrenergic nerves as revealed by histofluorescence.
  Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 1992 Flach AJ, Donahue ME
• Nerve terminal degeneration in the rat iris observed following chronic topical 2% epinephrine and 0.1% dipivalyl epinephrine: a quantitative comparison of electron microscopic observations and tissue norepinephrine levels.
  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 1992 Flach AJ, Donahue ME, Wood IS
• Improvement in visual acuity in chronic aphakic and pseudophakic cystoid macular edema after treatment with topical 0.5% ketorolac tromethamine.
  American journal of ophthalmology 1991 Flach AJ, Jampol LM, Weinberg D, Kraff MC, Yannuzzi LA, Campo RV, Neumann AC, Cupples HP, Lefler WH, Pulido JS
• Glaucoma treatment and pregnancy.
  Archives of ophthalmology (Chicago, Ill. : 1960) 1991 Flach AJ
• Amiodarone-induced lens opacities: an 8-year follow-up study.
  Archives of ophthalmology (Chicago, Ill. : 1960) 1990 Flach AJ, Dolan BJ
• Prophylaxis of aphakic cystoid macular edema without corticosteroids. A paired-comparison, placebo-controlled double-masked study.
  Ophthalmology 1990 Flach AJ, Stegman RC, Graham J, Kruger LP
• Episcleritis, conjunctivitis, and keratitis as ocular manifestations of Lyme disease.
  Ophthalmology 1990 Flach AJ, Lavoie PE
• The effect of ketorolac tromethamine in reducing postoperative inflammation: double-mask parallel comparison with dexamethasone.
  Annals of ophthalmology 1989 Flach AJ, Jaffe NS, Akers WA
• Cystoid macular edema following cataract surgery.
  Archives of ophthalmology (Chicago, Ill. : 1960) 1989 Flach AJ
• The effect of ketorolac tromethamine solution 0.5% in reducing postoperative inflammation after cataract extraction and intraocular lens implantation.
  Ophthalmology 1988 Flach AJ, Lavelle CJ, Olander KW, Retzlaff JA, Sorenson LW
• The quantitative effect of 0.5% ketorolac tromethamine solution and 0.1% dexamethasone sodium phosphate solution on postsurgical blood-aqueous barrier.
  Archives of ophthalmology (Chicago, Ill. : 1960) 1988 Flach AJ, Kraff MC, Sanders DR, Tanenbaum L
• Quantitative assessment of postsurgical breakdown of the blood-aqueous barrier following administration of 0.5% ketorolac tromethamine solution. A double-masked, paired comparison with vehicle-placebo solution study.
  Archives of ophthalmology (Chicago, Ill. : 1960) 1988 Flach AJ, Graham J, Kruger LP, Stegman RC, Tanenbaum L
• Topical prostaglandin E2 effects on normal human intraocular pressure.
  Journal of ocular pharmacology 1988 Flach AJ, Eliason JA
• Effectiveness of ketorolac tromethamine 0.5% ophthalmic solution for chronic aphakic and pseudophakic cystoid macular edema.
  American journal of ophthalmology 1987 Flach AJ, Dolan BJ, Irvine AR
• Ocular hypertensive responses in pigmented rabbits following different methods of waterloading.
  Journal of ocular pharmacology 1986 Flach AJ, Peterson JS, Donahue ME
• Dangers of ocular instillation of medications.
  The Western journal of medicine 1985 Flach AJ
• Amiodarone keratopathy and lens opacities.
  Journal of the American Optometric Association 1985 Dolan BJ, Flach AJ, Peterson JS
• Anterior subcapsular cataracts: a review of potential etiologies.
  Annals of ophthalmology 1985 Flach AJ, Peterson JS, Dolan BJ
• The therapy of Adie's syndrome with dilute pilocarpine hydrochloride solutions.
  Journal of ocular pharmacology 1985 Flach AJ, Dolan BJ
• Adie's syndrome: a medical treatment for symptomatic patients.
  Annals of ophthalmology 1984 Flach AJ, Dolan BJ
• The use of amiodarone in children.
  Pacing and clinical electrophysiology : PACE 1984 Flach AJ, Dolan B, Sudduth B
• Local ocular hypotensive effect of topically applied acetazolamide.
  American journal of ophthalmology 1984 Flach AJ, Peterson JS, Seligmann KA
• Ophthalmology-Important Advances in Clinical Medicine: Severe Systemic Effects From Topically Applied beta-Adrenergic Blocking Agents.
  The Western journal of medicine 1984 Flach AJ
• Post-ganglionic chemical sympathectomy of the cat nictitating membrane following systemic epinephrine: degeneration of nerve terminals followed by regeneration.
  Experimental eye research 1983 Flach AJ, Roizen MF, Wood IS, Peterson JS
• Amiodarone-induced lens opacities.
  Archives of ophthalmology (Chicago, Ill. : 1960) 1983 Flach AJ, Dolan BJ, Sudduth B, Weddell J
• A registry of potential product substitutions of particular danger for ophthalmology.
  American journal of ophthalmology 1983 Flach AJ
• Eyewash mistaken for contact lens soaking solution.
  American journal of ophthalmology 1983 Flach AJ, Sorenson JA
• Ptosis in the rat following topically administered 2% epinephrine.
  Investigative ophthalmology & visual science 1983 Flach AJ, Peterson JS, Roizen MF, Wood IS
• Chromatopsia related to afterimages.
  American journal of ophthalmology 1982 Flach AJ, Stone DR, Becker CE, Peterson JS
• Cortisporin dispensing error.
  American journal of ophthalmology 1982 Flach A, Murphy A
• Fatal aplastic anemia following topical administration of ophthalmic chloramphenicol.
  American journal of ophthalmology 1982 Flach AJ
• Photosensitivity to topically applied sulfisoxazole ointment: evidence for a phototoxic reaction.
  Archives of ophthalmology (Chicago, Ill. : 1960) 1982 Flach AJ, Peterson JS, Mathias CG
• Chloramphenicol and aplastic anemia.
  American journal of ophthalmology 1982 Flach AJ
• Degeneration of nerve terminals in cats following systemic epinephrine: depletion of tissue norepinephrine correlated with ultrastructural changes.
  Experimental eye research 1981 Flach AJ, Peterson JS, Wood I, Roizen MF
• Photosensitivity to sulfisoxazole ointment.
  Archives of ophthalmology (Chicago, Ill. : 1960) 1981 Flach A
• Supersensitivity to topical epinephrine after long-term epinephrine therapy.
  Archives of ophthalmology (Chicago, Ill. : 1960) 1980 Flach AJ, Kramer SG
• The fluorescein appearance test for lacrimal obstruction.
  Annals of ophthalmology 1979 Flach A
• An electron microscopic study of degeneration of nerve terminals after administration of epinephrine.
  Experimental eye research 1978 Flach A, Wood I
• Symblepharon in sarcoidosis.
  American journal of ophthalmology 1978 Flach A
• Fluorescein oropharyngoscopy.
  American journal of ophthalmology 1976 Flach A
• The pilocarpine Ocusert Delivery System.
  Transactions of the Pacific Coast Oto-Ophthalmological Society annual meeting 1974 Flach A
• [Intra vitam microscopic observations on capillaries and arterioles of the periphery of the lung following various stimuli].
  Bibliotheca anatomica 1965 Flach A