Alexis Talbot, PhD
Postdoctoral Scholar
Medicine
School of Medicine

Education & Training

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• Immunology Saint Louis hospital 10/2017
• M.D Haematology Saint Louis hospital 10/2016
• M.S Haematology Saint Louis hospital 10/2016

Interests

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• haematology
• multiple myeloma
• CAR T cells
• T cell engineering

Websites

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• @@DrAlexisTalbot on Twitter (twitter.com)

Publications (6)

Top publication keywords:
Genetic EngineeringPrecursor Cell Lymphoblastic Leukemia-LymphomaB-Cell Maturation AntigenCRISPR-Cas SystemsImmunotherapy, AdoptiveDNA, Single-StrandedProteasome InhibitorsNeoplasm Recurrence, LocalMultiple MyelomaCleavage And Polyadenylation Specificity FactorImmunotherapyDependovirusLymphoma, B-CellBurkitt LymphomaT-Lymphocytes

• Overcoming proteasome inhibitor resistance in the immunotherapy era.
  Trends in pharmacological sciences 2023 Patiño-Escobar B, Talbot A, Wiita AP
• An evolved AAV variant enables efficient genetic engineering of murine T cells.
  Cell 2023 Nyberg WA, Ark J, To A, Clouden S, Reeder G, Muldoon JJ, Chung JY, Xie WH, Allain V, Steinhart Z, Chang C, Talbot A, Kim S, Rosales A, Havlik LP, Pimentel H, Asokan A, Eyquem J
• Pooled screening of CAR T cells identifies diverse immune signaling domains for next-generation immunotherapies.
  Science translational medicine 2022 Goodman DB, Azimi CS, Kearns K, Talbot A, Garakani K, Garcia J, Patel N, Hwang B, Lee D, Park E, Vykunta VS, Shy BR, Ye CJ, Eyquem J, Marson A, Bluestone JA, Roybal KT
• NUDT21 limits CD19 levels through alternative mRNA polyadenylation in B cell acute lymphoblastic leukemia.
  Nature immunology 2022 Witkowski MT, Lee S, Wang E, Lee AK, Talbot A, Ma C, Tsopoulidis N, Brumbaugh J, Zhao Y, Roberts KG, Hogg SJ, Nomikou S, Ghebrechristos YE, Thandapani P, Mullighan CG, Hochedlinger K, Chen W, Abdel-…
• High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails.
  Nature biotechnology 2022 Shy BR, Vykunta VS, Ha A, Talbot A, Roth TL, Nguyen DN, Pfeifer WG, Chen YY, Blaeschke F, Shifrut E, Vedova S, Mamedov MR, Chung JJ, Li H, Yu R, Wu D, Wolf J, Martin TG, Castro CE, Ye L, Esensten JH, …
• The surfaceome of multiple myeloma cells suggests potential immunotherapeutic strategies and protein markers of drug resistance.
  Nature communications 2022 Ferguson ID, Patiño-Escobar B, Tuomivaara ST, Lin YT, Nix MA, Leung KK, Kasap C, Ramos E, Nieves Vasquez W, Talbot A, Hale M, Naik A, Kishishita A, Choudhry P, Lopez-Girona A, Miao W, Wong SW, Wolf JL…