Alexander Haddad, MD
Resident
Neurological Surgery
School of Medicine
Awards
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- Catalyst Award, University of California, San Francisco, 2023
- Catalyst Award, University of California, San Francisco, 2022
- Krevans Award for Excellence in Patient Care, Zuckerberg San Francisco General Hospital and Trauma Center, 2022
- Long-Term Research Dean's Prize, University of California, San Francisco School of Medicine, 2021
- MD with Distinction, University of California, San Francisco School of Medicine, 2021
- Steinhart Award, University of California, San Francisco School of Medicine, 2021
- First Place, "IT for Society", UC Berkeley Big Ideas Competition, 2017
- Postbaccalaureate Intramural Research Training Award (IRTA), National Institutes of Health, 2016
- Biological Sciences Department Senior Appreciation Award, DePaul University, 2015
- Departmental Award for Outstanding Performance in Biochemistry, DePaul University, 2015
- Departmental Award for Outstanding Performance in Organic Chemistry, DePaul University, 2015
- summa cum laude, DePaul University, 2015
Education & Training
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- Residency Neurological Surgery University of California, San Francisco 06/2028
- MD Medicine University of California, San Francisco 05/2021
Grants and Projects
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- A Synthetic Replicating Retroviral Platform for Glioblastoma Viral Immunotherapy, UCSF CATALYST PROGRAM, 2023-2024
- Synthetic Novel Replicating Retroviral Gene Therapy Platform for the Treatment of Glioblastoma, UCSF CATALYST PROGRAM, 2022-2023
Publications (70)
Top publication keywords:
Brain NeoplasmsSpinal NeoplasmsOncolytic VirotherapyCentral Nervous System Viral DiseasesT-Lymphocytes, CytotoxicMyelitisGonadotrophsBrain Injuries, TraumaticSpinal FusionGlioblastomaGliomaPituitary NeoplasmsAdenomaLymphocytes, NullNeuromuscular Diseases
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Strategies to Improve Drug Delivery Across the Blood-Brain Barrier for Glioblastoma.
Current neurology and neuroscience reports 2024 Narsinh KH, Perez E, Haddad AF, Young JS, Savastano L, Villanueva-Meyer JE, Winkler E, de Groot J -
Minimally Invasive Endoscopic Evacuation of Cerebellar Intracerebral Hemorrhage: An Illustrative Case Report.
Stroke 2024 Elguindy MM, Haddad AF, Lu A, Savastano LE -
Associations between recurrence patterns and outcome in glioblastoma patients undergoing re-resection: A complementary report of the RANO resect group.
Neuro-oncology 2024 Karschnia P, Dono A, Young JS, Juenger ST, Teske N, Häni L, Sciortino T, Mau CY, Bruno F, Nunez L, Morshed RA, Haddad AF, Weller M, van den Bent M, Thon N, Beck J, Hervey-Jumper S, Molinaro AM, Tandon… -
Surgical management and outcome of newly diagnosed glioblastoma without contrast enhancement (low-grade appearance): a report of the RANO resect group.
Neuro-oncology 2024 Karschnia P, Dietrich J, Bruno F, Dono A, Juenger ST, Teske N, Young JS, Sciortino T, Häni L, van den Bent M, Weller M, Vogelbaum MA, Morshed RA, Haddad AF, Molinaro AM, Tandon N, Beck J, Schnell O, … -
Patient-reported outcome measures in cerebrovascular neurosurgery.
Journal of neurosurgery 2023 Ramesh R, Haddad AF, Letchuman V, Lee YM, Rinaldo L, Abla AA, Savastano LE, Raper DMS
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Asleep triple-modality motor mapping for perirolandic gliomas: an update on outcomes.
Journal of neurosurgery 2023 Morshed RA, Cummins DD, Clark JP, Young JS, Haddad AF, Gogos AJ, Hervey-Jumper SL, Berger MS -
Prognostic evaluation of re-resection for recurrent glioblastoma using the novel RANO classification for extent of resection: A report of the RANO resect group.
Neuro-oncology 2023 Karschnia P, Dono A, Young JS, Juenger ST, Teske N, Häni L, Sciortino T, Mau CY, Bruno F, Nunez L, Morshed RA, Haddad AF, Weller M, van den Bent M, Beck J, Hervey-Jumper S, Molinaro AM, Tandon N, Rudà… -
Socioeconomic differences between medically and surgically treated prolactinomas: a retrospective review of 598 patients.
Journal of neurosurgery 2023 Osorio RC, Haddad AF, Hart DM, Goldrich N, Badani A, Kabir AS, Juncker R, Oh JY, Carrete L, Peeran Z, Chalif EJ, Zheng AC, Braunstein S, Theodosopoulos PV, El-Sayed IH, Gurrola J, Kunwar S, Blevins LS… -
Middle meningeal artery embolization with polyvinyl alcohol particles in a patient with ophthalmic artery origin from middle meningeal artery: Case report and technical note.
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences 2023 Lee YM, Mattay RR, Haddad AF, Rinaldo L, Savastano L -
Prognostic validation of a new classification system for extent of resection in glioblastoma: A report of the RANO resect group.
Neuro-oncology 2023 Karschnia P, Young JS, Dono A, Häni L, Sciortino T, Bruno F, Juenger ST, Teske N, Morshed RA, Haddad AF, Zhang Y, Stoecklein S, Weller M, Vogelbaum MA, Beck J, Tandon N, Hervey-Jumper S, Molinaro AM, … -
Single-cell RNA sequencing and spatial transcriptomics reveal cancer-associated fibroblasts in glioblastoma with protumoral effects.
The Journal of clinical investigation 2023 Jain S, Rick JW, Joshi RS, Beniwal A, Spatz J, Gill S, Chang AC, Choudhary N, Nguyen AT, Sudhir S, Chalif EJ, Chen JS, Chandra A, Haddad AF, Wadhwa H, Shah SS, Choi S, Hayes JL, Wang L, Yagnik G, … -
CDKN2A/B co-deletion is associated with increased risk of local and distant intracranial recurrence after surgical resection of brain metastases.
Neuro-oncology advances 2023 Morshed RA, Nguyen MP, Cummins DD, Saggi S, Young JS, Haddad AF, Goldschmidt E, Chang EF, McDermott MW, Berger MS, Theodosopoulos PV, Hervey-Jumper SL, Daras M, Aghi MK -
Recent advances in the molecular prognostication of meningiomas.
Frontiers in oncology 2023 Wang EJ, Haddad AF, Young JS, Morshed RA, Wu JPH, Salha DM, Butowski N, Aghi MK -
Combined retropleural thoracotomy and posterior spinal approach for thoracic dumbbell Schwannoma: Case series and review of the literature.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2022 Kurland DB, Lau D, Dalle Ore CL, Haddad A, Deviren V, Ames CP -
Novel intraoperative strategies for enhancing tumor control: Future directions.
Neuro-oncology 2022 Haddad AF, Aghi MK, Butowski N -
Correlation between tumor volume and serum prolactin and its effect on surgical outcomes in a cohort of 219 prolactinoma patients.
Journal of neurosurgery 2022 Osorio RC, Pereira MP, Oh T, Joshi RS, Haddad AF, Pereira KM, Donohue KC, Peeran Z, Carson W, Badani A, Wang EJ, Sudhir S, Chandra A, Jain S, Beniwal A, Gurrola J, El-Sayed IH, Blevins LS, … -
Anterolateral Thigh Free Flap Versus Thigh Split Thickness Skin Graft: Comparison of Morbidity in the First 30 Days.
Facial plastic surgery & aesthetic medicine 2022 Benjamin T, Zebolsky AL, Haddad AF, Ochoa E, Plonowska-Hirschfeld KA, Park AM, Seth R, Knott PD -
TERT promotor status does not add prognostic information in IDH-wildtype glioblastomas fulfilling other diagnostic WHO criteria: A report of the RANO resect group.
Neuro-oncology advances 2022 Karschnia P, Young JS, Dono A, Häni L, Juenger ST, Sciortino T, Bruno F, Teske N, Morshed RA, Haddad AF, Zhang Y, Stoecklein S, Vogelbaum MA, Beck J, Tandon N, Hervey-Jumper S, Molinaro AM, Rudà R, … -
Posterior-based resection of spinal meningiomas: an institutional experience of 141 patients with an average of 28 months of follow-up.
Journal of neurosurgery. Spine 2022 Haddad AF, Safaee MM, Pereira MP, Oh JY, Lau D, Tan LA, Clark AJ, Chou D, Mummaneni PV, Ames CP -
Predictors of Extreme Hospital Length of Stay After Traumatic Brain Injury.
World neurosurgery 2022 Yue JK, Krishnan N, Chyall L, Haddad AF, Vega P, Caldwell DJ, Umbach G, Tantry E, Tarapore PE, Huang MC, Manley GT, DiGiorgio AM -
CDK 4/6 inhibitors for the treatment of meningioma.
Frontiers in oncology 2022 Young JS, Kidwell RL, Zheng A, Haddad AF, Aghi MK, Raleigh DR, Schulte JD, Butowski NA -
Cardiac Complications After 3-Column Osteotomy for Adult Spinal Deformity Patients With Formal Cardiac Clearance: Identifying Key Risk Factors and Threshold Cutoffs Via Recursive Partitioning Analysis.
Neurosurgery 2022 Lau D, Haddad AF, Joshi RS, Deviren V, Ames CP -
Evacuation of a multi-loculated acute-on-chronic subdural hematoma using tandem bedside subdural evacuation port systems.
Trauma case reports 2022 Yue JK, Haddad AF, Wang AS, Caldwell DJ, Umbach G, Digiorgio AM, Tarapore PE, Huang MC, Manley GT -
The Hybrid Operative Suite with Intraoperative Biplane Rotational Angiography in Pediatric Cerebrovascular Neurosurgery: Utility and Lessons Learned.
Pediatric neurosurgery 2022 Yue JK, Chang D, Caton MT, Haddad AF, Dalle Ore CL, Wozny TA, Oh T, Wang AS, Tonetti DA, Auguste KI, Sun PP, Cooke DL, Hetts SW, Abla AA, Gupta N, Roland JL -
In Reply: The Morbidity and Mortality of Surgery for Traumatic Brain Injury in Geriatric Patients: A Study of Over 100 000 Patient Cases.
Neurosurgery 2022 Haddad AF, DiGiorgio AM, Tarapore PE -
Pituitary adenoma in the elderly: surgical outcomes and treatment trends in the United States.
Journal of neurosurgery 2022 Chalif EJ, Morshed RA, Young JS, Haddad AF, Jain S, Aghi MK -
FLAIRectomy: Resecting beyond the Contrast Margin for Glioblastoma.
Brain sciences 2022 Haddad AF, Young JS, Morshed RA, Berger MS -
Resistance to immune checkpoint blockade: Mechanisms, counter-acting approaches, and future directions.
Seminars in cancer biology 2022 Haddad AF, Young JS, Gill S, Aghi MK -
Pearls and Pitfalls of Awake Spine Surgery: A Simplified Patient-Selection Algorithm.
World neurosurgery 2022 Letchuman V, Agarwal N, Mummaneni VP, Wang MY, Shabani S, Patel A, Rivera J, Haddad A, Le V, Chang JM, Chou D, Gandhi S, Mummaneni PV -
Incidence and Risk Factors of Mechanical Complications After Posterior-Based Osteotomies for Correction of Moderate to Severe Adult Cervical Deformity: 1-Year and 2-Year Follow-up.
Neurosurgery 2022 Lau D, Joshi RS, Haddad AF, Deviren V, Ames CP -
The immunology of low-grade gliomas.
Neurosurgical focus 2022 Haddad AF, Young JS, Oh JY, Okada H, Aghi MK -
Identifying risk factors for postoperative diabetes insipidus in more than 2500 patients undergoing transsphenoidal surgery: a single-institution experience.
Journal of neurosurgery 2022 Joshi RS, Pereira MP, Osorio RC, Oh T, Haddad AF, Pereira KM, Donohue KC, Peeran Z, Sudhir S, Jain S, Beniwal A, Chandra A, Han SJ, Rolston JD, Theodosopoulos PV, Kunwar S, Blevins LS, Aghi MK -
Do social determinants of health impact access to neurosurgical care in the United States? A workforce perspective.
Journal of neurosurgery 2022 Perera S, Hervey-Jumper SL, Mummaneni PV, Barthélemy EJ, Haddad AF, Marotta DA, Burke JF, Chan AK, Manley GT, Tarapore PE, Huang MC, Dhall SS, Chou D, Orrico KO, DiGiorgio AM -
The effect of levetiracetam treatment on survival in patients with glioblastoma: a systematic review and meta-analysis.
Journal of neuro-oncology 2022 Chen JS, Clarke R, Haddad AF, Wang EJ, Lacroix M, Sarkar IN, Zand R, Chen ES, Toms SA -
Reducing complication rates for repeat craniotomies in glioma patients: a single-surgeon experience and comparison with the literature.
Acta neurochirurgica 2021 Morshed RA, Young JS, Gogos AJ, Haddad AF, McMahon JT, Molinaro AM, Sudhakar V, Al-Adli N, Hervey-Jumper SL, Berger MS -
Pseudo-insular glioma syndrome: illustrative cases.
Journal of neurosurgery. Case lessons 2021 Haddad AF, Young JS, Morshed RA, Josephson SA, Cha S, Berger MS -
Immunotherapy Resistance in Glioblastoma.
Frontiers in genetics 2021 Wang EJ, Chen JS, Jain S, Morshed RA, Haddad AF, Gill S, Beniwal AS, Aghi MK -
Management of Malpositioned Cervical Interfacet Spacers: An Institutional Case Series.
Cureus 2021 Garcia JH, Haddad AF, Patel A, Safaee MM, Pennicooke B, Mummaneni PV, Clark AJ -
Awake spinal surgery: simplifying the learning curve with a patient selection algorithm.
Neurosurgical focus 2021 Letchuman V, Agarwal N, Mummaneni VP, Wang MY, Shabani S, Patel A, Rivera J, Haddad AF, Le V, Chang JM, Chou D, Gandhi S, Mummaneni PV -
The Morbidity and Mortality of Surgery for Traumatic Brain Injury in Geriatric Patients: A Study of Over 100 000 Patient Cases.
Neurosurgery 2021 Haddad AF, DiGiorgio AM, Lee YM, Lee AT, Burke JF, Huang MC, Dhall SS, Manley GT, Tarapore PE -
Microsurgical resection of an intravestibular schwannoma: a review of surgical technique and management considerations.
Neurosurgical focus: Video 2021 Morshed RA, Haddad AF, Raygor KP, Xu MJ, Limb CJ, Theodosopoulos PV -
Incidence of Chronic Periscapular Pain After Adult Thoracolumbar Deformity Correction and Impact on Outcomes.
Neurospine 2021 Haddad AF, Scheer JK, Fury MT, Smith JS, Deviren V, Ames CP -
Multiple-rod constructs and use of bone morphogenetic protein-2 in relation to lower rod fracture rates in 141 patients with adult spinal deformity who underwent lumbar pedicle subtraction osteotomy.
Journal of neurosurgery. Spine 2021 Lyu Q, Lau D, Haddad AF, Deviren V, Ames CP -
Lymphocele after anterior lumbar interbody fusion: a review of 1322 patients.
Journal of neurosurgery. Spine 2021 Scheer JK, Haddad AF, Chan AK, Eichler CM, Tay B, Burch S, Chou D, Ames CP, Mummaneni PV -
Reduced proximal junctional failure with ligament augmentation in adult spinal deformity: a series of 242 cases with a minimum 1-year follow-up.
Journal of neurosurgery. Spine 2021 Safaee MM, Haddad AF, Fury M, Maloney PR, Scheer JK, Lau D, Deviren V, Ames CP -
Mouse models of glioblastoma for the evaluation of novel therapeutic strategies.
Neuro-oncology advances 2021 Haddad AF, Young JS, Amara D, Berger MS, Raleigh DR, Aghi MK, Butowski NA -
The Natural History of Spinal Cord Injury.
Neurosurgery clinics of North America 2021 Haddad AF, Burke JF, Dhall SS -
Telemedicine in Neurosurgery: Standardizing the Spinal Physical Examination Using A Modified Delphi Method.
Neurospine 2021 Haddad AF, Burke JF, Mummaneni PV, Chan AK, Safaee MM, Knightly JJ, Mayer RR, Pennicooke BH, Digiorgio AM, Weinstein PR, Clark AJ, Chou D, Dhall SS -
An analysis of tumor-related potential spinal column instability (Spine Instability Neoplastic Scores 7-12) eventually requiring surgery with a 1-year follow-up.
Neurosurgical focus 2021 Vargas E, Lockney DT, Mummaneni PV, Haddad AF, Rivera J, Tan X, Jamieson A, Mahmoudieh Y, Berven S, Braunstein SE, Chou D -
Plurihormonal PIT-1-Positive Pituitary Adenomas: A Systematic Review and Single-Center Series.
World neurosurgery 2021 Andrews JP, Joshi RS, Pereira MP, Oh T, Haddad AF, Pereira KM, Osorio RC, Donohue KC, Peeran Z, Sudhir S, Jain S, Beniwal A, Chopra AS, Sandhu NS, Tihan T, Blevins L, Aghi MK -
Pathologic Findings Associated With a Case of Acute Flaccid Myelitis.
Journal of neuropathology and experimental neurology 2021 Haddad AF, Hofmann JW, Oh T, Jacques L, Yu G, Chiu C, Nolan A, Strober J, Gupta N -
Multilevel Pedicle Subtraction Osteotomy for Correction of Severe Rigid Adult Spinal Deformities: A Case Series, Indications, Considerations, and Literature Review.
Operative neurosurgery (Hagerstown, Md.) 2021 Lau D, Haddad AF, Fury MT, Deviren V, Ames CP -
Using viral vectors to deliver local immunotherapy to glioblastoma.
Neurosurgical focus 2021 Haddad AF, Young JS, Aghi MK -
Preoperative Applications of Navigated Transcranial Magnetic Stimulation.
Frontiers in neurology 2021 Haddad AF, Young JS, Berger MS, Tarapore PE -
Anterior Lumbar Interbody Fusion With Cage Retrieval for the Treatment of Pseudarthrosis After Transforaminal Lumbar Interbody Fusion: A Single-Institution Case Series.
Operative neurosurgery (Hagerstown, Md.) 2021 Safaee MM, Tenorio A, Haddad AF, Wu B, Hu SS, Tay B, Burch S, Berven SH, Deviren V, Dhall SS, Chou D, Mummaneni PV, Eichler CM, Ames CP, Clark AJ -
Immunologic aspects of viral therapy for glioblastoma and implications for interactions with immunotherapies.
Journal of neuro-oncology 2021 Haddad AF, Young JS, Mummaneni NV, Kasahara N, Aghi MK -
Navigated TMS in the ICU: Introducing Motor Mapping to the Critical Care Setting.
Brain sciences 2020 Schramm S, Haddad AF, Chyall L, Krieg SM, Sollmann N, Tarapore PE -
Risk factors for determining length of intensive care unit and hospital stays following correction of cervical deformity: evaluation of early severe adverse events.
Journal of neurosurgery. Spine 2020 Joshi RS, Lau D, Haddad AF, Deviren V, Ames CP -
Higher cytolytic score correlates with an immunosuppressive tumor microenvironment and reduced survival in glioblastoma.
Scientific reports 2020 Haddad AF, Chen JS, Oh T, Pereira MP, Joshi RS, Aghi MK -
Clinical characteristics and outcomes in elderly patients undergoing transsphenoidal surgery for nonfunctioning pituitary adenoma.
Neurosurgical focus 2020 Pereira MP, Oh T, Joshi RS, Haddad AF, Pereira KM, Osorio RC, Donohue KC, Peeran Z, Sudhir S, Jain S, Beniwal A, Gurrola J, El-Sayed IH, Blevins LS, Theodosopoulos PV, Kunwar S, Aghi MK -
The Effect of Systemic Tranexamic Acid on Hypercoagulable Complications and Perioperative Outcomes Following Three-Column Osteotomy for Adult Spinal Deformity.
Global spine journal 2020 Haddad AF, Ames CP, Safaee M, Deviren V, Lau D -
WHO Grade I Meningioma Recurrence: Identifying High Risk Patients Using Histopathological Features and the MIB-1 Index.
Frontiers in oncology 2020 Haddad AF, Young JS, Kanungo I, Sudhir S, Chen JS, Raleigh DR, Magill ST, McDermott MW, Aghi MK -
Asymmetrical pedicle subtraction osteotomy for correction of concurrent sagittal-coronal imbalance in adult spinal deformity: a comparative analysis.
Journal of neurosurgery. Spine 2020 Lau D, Haddad AF, Deviren V, Ames CP -
Complication profile associated with S1 pedicle subtraction osteotomy compared with 3-column osteotomies at other thoracolumbar levels for adult spinal deformity: series of 405 patients with 9 S1 osteotomies.
Journal of neurosurgery. Spine 2020 Lau D, Haddad AF, Deviren V, Ames CP -
Factors affecting approach selection for minimally invasive versus open surgery in the treatment of adult spinal deformity: analysis of a prospective, nonrandomized multicenter study.
Journal of neurosurgery. Spine 2020 Park P, Than KD, Mummaneni PV, Nunley PD, Eastlack RK, Uribe JS, Wang MY, Le V, Fessler RG, Okonkwo DO, Kanter AS, Anand N, Chou D, Fu KG, Haddad AF, Shaffrey CI, Mundis GM, International Spine Study … -
Clinical characteristics and outcomes of null-cell versus silent gonadotroph adenomas in a series of 1166 pituitary adenomas from a single institution.
Neurosurgical focus 2020 Haddad AF, Young JS, Oh T, Pereira MP, Joshi RS, Pereira KM, Osorio RC, Donohue KC, Peeran Z, Sudhir S, Jain S, Beniwal A, Chopra AS, Sandhu NS, Theodosopoulos PV, Kunwar S, El-Sayed IH, Gurrola J, … -
Targeting mitochondrial and cytosolic substrates of TRIT1 isopentenyltransferase: Specificity determinants and tRNA-i6A37 profiles.
PLoS genetics 2020 Khalique A, Mattijssen S, Haddad AF, Chaudhry S, Maraia RJ -
Artificial Intelligence for Adult Spinal Deformity.
Neurospine 2019 Joshi RS, Haddad AF, Lau D, Ames CP -
A Reduced Exogenous Steroid Taper for Postoperative Brain Tumor Patients-A Case-Control Study.
World neurosurgery 2019 Breshears JD, Haddad AF, Viner J, Rau J, Sankaran S, McDermott MW -
Using proximity biotinylation to detect herpesvirus entry glycoprotein interactions: Limitations for integral membrane glycoproteins.
Journal of virological methods 2015 Lajko M, Haddad AF, Robinson CA, Connolly SA