Alexander Gottschalk, MD, PhD
Professor
Radiation Oncology
School of Medicine

I am responsible for patient simulations, treatment planning, supervision of external-beam radiation therapy, on-treatment visits, and follow-up visits. In addition, I am involved in the brachytherapy, intra-operative radiation therapy and stereotactic body radiotherapy programs. I attend tumor boards for GU, Thoracic, GI, orthopedic oncology programs and at the Veterans Administration Hospital. I work very closely with radiation oncology residents and medical students in all the above activities. I am the Director of the CyberKnife Radiosurgery Program at UCSF and proctor other faculty in this area. As Vice Chair of clinical services I over see clinical operations at the Mount Zion site, and over see the site directors at both the Parnassus Mission Bay and Washington Hospital.

• Rapid and reversible optogenetic silencing of synaptic transmission by clustering of synaptic vesicles.
  Nature communications 2022 Vettkötter D, Schneider M, Goulden BD, Dill H, Liewald J, Zeiler S, Guldan J, Ates YA, Watanabe S, Gottschalk A
• WormRuler: A software to track body length used to characterize a super red-shifted channelrhodopsin in Caenorhabditis elegans.
  microPublication biology 2022 Seidenthal M, Vettkötter D, Gottschalk A
• Addition of Enzalutamide to Leuprolide and Definitive Radiation Therapy Is Tolerable and Effective in High-Risk Localized or Regional Nonmetastatic Prostate Cancer: Results From a Phase 2 Trial.
  Advances in radiation oncology 2022 Shee K, de la Calle CM, Chang AJ, Wong AC, Feng FY, Gottschalk AR, Carroll PR, Nguyen HG
• Microbial Rhodopsin Optogenetic Tools: Application for Analyses of Synaptic Transmission and of Neuronal Network Activity in Behavior.
  Methods in molecular biology (Clifton, N.J.) 2022 Bergs A, Henss T, Glock C, Nagpal J, Gottschalk A
• Photoactivated Adenylyl Cyclases as Optogenetic Modulators of Neuronal Activity.
  Methods in molecular biology (Clifton, N.J.) 2022 Henss T, Schneider M, Vettkötter D, Costa WS, Liewald JF, Gottschalk A
• BiPOLES is an optogenetic tool developed for bidirectional dual-color control of neurons.
  Nature communications 2021 Vierock J, Rodriguez-Rozada S, Dieter A, Pieper F, Sims R, Tenedini F, Bergs ACF, Bendifallah I, Zhou F, Zeitzschel N, Ahlbeck J, Augustin S, Sauter K, Papagiakoumou E, Gottschalk A, Soba P, Emiliani …
• Optogenetic tools for manipulation of cyclic nucleotides functionally coupled to cyclic nucleotide-gated channels.
  British journal of pharmacology 2021 Henß T, Nagpal J, Gao S, Scheib U, Pieragnolo A, Hirschhäuser A, Schneider-Warme F, Hegemann P, Nagel G, Gottschalk A
• Synapsin Is Required for Dense Core Vesicle Capture and cAMP-Dependent Neuropeptide Release.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 Yu SC, Liewald JF, Shao J, Steuer Costa W, Gottschalk A
• Stereotactic Body Radiation Therapy and High-Dose-Rate Brachytherapy Boost in Combination With Intensity Modulated Radiation Therapy for Localized Prostate Cancer: A Single-Institution Propensity Score Matched Analysis.
  International journal of radiation oncology, biology, physics 2020 Chen WC, Li Y, Lazar A, Altun A, Descovich M, Nano T, Ziemer B, Sudhyadhom A, Cunha A, Thomas H, Gottschalk A, Hsu IC, Roach M
• Evaluation of a National Comprehensive Cancer Network Guidelines-Based Decision Support Tool in Patients With Non-Small Cell Lung Cancer: A Nonrandomized Clinical Trial.
  JAMA network open 2020 Wu SY, Lazar AA, Gubens MA, Blakely CM, Gottschalk AR, Jablons DM, Jahan TM, Wang VEH, Dunbar TL, Wong ML, Chan JW, Guthrie W, Belkora J, Yom SS
• Context-dependent operation of neural circuits underlies a navigation behavior in Caenorhabditis elegans.
  Proceedings of the National Academy of Sciences of the United States of America 2020 Ikeda M, Nakano S, Giles AC, Xu L, Costa WS, Gottschalk A, Mori I
• Stereotactic Body Radiation Therapy of Adrenal Metastases: A Pooled Meta-Analysis and Systematic Review of 39 Studies with 1006 Patients.
  International journal of radiation oncology, biology, physics 2020 Chen WC, Baal JD, Baal U, Pai J, Gottschalk A, Boreta L, Braunstein SE, Raleigh DR
• Epidermal Growth Factor Signaling Promotes Sleep through a Combined Series and Parallel Neural Circuit.
  Current biology : CB 2019 Konietzka J, Fritz M, Spiri S, McWhirter R, Leha A, Palumbos S, Costa WS, Oranth A, Gottschalk A, Miller DM, Hajnal A, Bringmann H
• Rhodopsin-based voltage imaging tools for use in muscles and neurons of Caenorhabditis elegans.
  Proceedings of the National Academy of Sciences of the United States of America 2019 Azimi Hashemi N, Bergs ACF, Schüler C, Scheiwe AR, Steuer Costa W, Bach M, Liewald JF, Gottschalk A
• Using a Robust and Sensitive GFP-Based cGMP Sensor for Real-Time Imaging in Intact Caenorhabditis elegans.
  Genetics 2019 Woldemariam S, Nagpal J, Hill T, Li J, Schneider MW, Shankar R, Futey M, Varshney A, Ali N, Mitchell J, Andersen K, Barsi-Rhyne B, Tran A, Costa WS, Krzyzanowski MC, Yu YV, Brueggemann C, Hamilton OS,…
• Dedicated Diagnostic Radiology/Radiation Oncology Rounds: Added Value Beyond Traditional Tumor Boards.
  Current problems in diagnostic radiology 2019 Kallianos KG, Muhoozi BN, Gottschalk A, Yom SS, Chan JW, Henry TS, Elicker BM, Ordovas KG, Naeger DM
• A Photoactivatable Botulinum Neurotoxin for Inducible Control of Neurotransmission.
  Neuron 2019 Liu Q, Sinnen BL, Boxer EE, Schneider MW, Grybko MJ, Buchta WC, Gibson ES, Wysoczynski CL, Ford CP, Gottschalk A, Aoto J, Tucker CL, Kennedy MJ
• Impact of Staging 68Ga-PSMA-11 PET Scans on Radiation Treatment Plansin Patients With Prostate Cancer.
  Urology 2018 Wu SY, Boreta L, Shinohara K, Nguyen H, Gottschalk AR, Hsu IC, Roach M, Westphalen AC, Feng FY, Carroll PR, Chang AJ, Hope TA
• Food Sensation Modulates Locomotion by Dopamine and Neuropeptide Signaling in a Distributed Neuronal Network.
  Neuron 2018 Oranth A, Schultheis C, Tolstenkov O, Erbguth K, Nagpal J, Hain D, Brauner M, Wabnig S, Steuer Costa W, McWhirter RD, Zels S, Palumbos S, Miller Iii DM, Beets I, Gottschalk A
• Expanding the Optogenetics Toolkit by Topological Inversion of Rhodopsins.
  Cell 2018 Brown J, Behnam R, Coddington L, Tervo DGR, Martin K, Proskurin M, Kuleshova E, Park J, Phillips J, Bergs ACF, Gottschalk A, Dudman JT, Karpova AY
• Functionally asymmetric motor neurons contribute to coordinating locomotion of Caenorhabditis elegans.
  eLife 2018 Tolstenkov O, Van der Auwera P, Steuer Costa W, Bazhanova O, Gemeinhardt TM, Bergs AC, Gottschalk A
• Phase I study of dose escalation to dominant intraprostatic lesions using high-dose-rate brachytherapy.
  Journal of contemporary brachytherapy 2018 Chapman CH, Braunstein SE, Pouliot J, Noworolski SM, Weinberg V, Cunha A, Kurhanewicz J, Gottschalk AR, Roach MI, Hsu IC
• Endophilin A and B Join Forces With Clathrin to Mediate Synaptic Vesicle Recycling in Caenorhabditis elegans.
  Frontiers in molecular neuroscience 2018 Yu SC, Jánosi B, Liewald JF, Wabnig S, Gottschalk A
• Influence of respiratory motion management technique on radiation pneumonitis risk with robotic stereotactic body radiation therapy.
  Journal of applied clinical medical physics 2018 Chapman CH, McGuinness C, Gottschalk AR, Yom SS, Garsa AA, Anwar M, Braunstein SE, Sudhyadhom A, Keall P, Descovich M
• Rhodopsin optogenetic toolbox v2.0 for light-sensitive excitation and inhibition in Caenorhabditis elegans.
  PloS one 2018 Bergs A, Schultheis C, Fischer E, Tsunoda SP, Erbguth K, Husson SJ, Govorunova E, Spudich JL, Nagel G, Gottschalk A, Liewald JF
• An optogenetic arrhythmia model to study catecholaminergic polymorphic ventricular tachycardia mutations.
  Scientific reports 2017 Fischer E, Gottschalk A, Schüler C
• ACR Appropriateness Criteria for external beam radiation therapy treatment planning for clinically localized prostate cancer, part II of II.
  Advances in radiation oncology 2017 Zaorsky NG, Showalter TN, Ezzell GA, Nguyen PL, Assimos DG, D'Amico AV, Gottschalk AR, Gustafson GS, Keole SR, Liauw SL, Lloyd S, McLaughlin PW, Movsas B, Prestidge BR, Taira AV, Vapiwala N, Davis BJ
• ACR Appropriateness Criteria® Locally Advanced, High-Risk Prostate Cancer.
  American journal of clinical oncology 2017 McLaughlin PW, Liss AL, Nguyen PL, Assimos DG, D'Amico AV, Gottschalk AR, Gustafson GS, Keole SR, Liauw SL, Lloyd S, Movsas B, Prestidge BR, Showalter TN, Taira AV, Vapiwala N, Davis BJ, Expert Panel …
• Respiration-Induced Intraorgan Deformation of the Liver: Implications for Treatment Planning in Patients Treated With Fiducial Tracking.
  Technology in cancer research & treatment 2017 Paulsson AK, Yom SS, Anwar M, Pinnaduwage D, Sudhyadhom A, Gottschalk AR, Chang AJ, Descovich M
• ACR appropriateness criteria: Permanent source brachytherapy for prostate cancer.
  Brachytherapy 2016 Davis BJ, Taira AV, Nguyen PL, Assimos DG, D'Amico AV, Gottschalk AR, Gustafson GS, Keole SR, Liauw SL, Lloyd S, McLaughlin PW, Movsas B, Prestidge BR, Showalter TN, Vapiwala N
• ACR Appropriateness Criteria® external beam radiation therapy treatment planning for clinically localized prostate cancer, part I of II.
  Advances in radiation oncology 2016 Expert Panel on Radiation Oncology-Prostate:, Zaorsky NG, Showalter TN, Ezzell GA, Nguyen PL, Assimos DG, D'Amico AV, Gottschalk AR, Gustafson GS, Keole SR, Liauw SL, Lloyd S, McLaughlin PW, Movsas B,…
• Correction: Endoscopic Gold Fiducial Marker Placement into the Bladder Wall to Optimize Radiotherapy Targeting for Bladder-Preserving Management of Muscle-Invasive Bladder Cancer: Feasibility and Initial Outcomes.
  PloS one 2016 Garcia MM, Gottschalk AR, Brajtbord J, Konety BR, Meng MV, Roach M, Carroll PR
• Hybrid minimally invasive Ivor Lewis esophagectomy after neoadjuvant chemoradiation yields excellent long-term survival outcomes with minimal morbidity.
  Journal of surgical oncology 2016 Woodard GA, Crockard JC, Clary-Macy C, Zoon-Besselink CT, Jones K, Korn WM, Ko AH, Gottschalk AR, Rogers SJ, Jablons DM
• Photoswitchable diacylglycerols enable optical control of protein kinase C.
  Nature chemical biology 2016 Frank JA, Yushchenko DA, Hodson DJ, Lipstein N, Nagpal J, Rutter GA, Rhee JS, Gottschalk A, Brose N, Schultz C, Trauner D
• Receiver operating curves and dose-volume analysis of late toxicity with stereotactic body radiation therapy for prostate cancer.
  Practical radiation oncology 2016 Zhang L, Johnson J, Gottschalk AR, Chang AJ, Hsu IC, Roach M, Seymour ZA
• Interfraction Anatomical Variability Can Lead to Significantly Increased Rectal Dose for Patients Undergoing Stereotactic Body Radiotherapy for Prostate Cancer.
  Technology in cancer research & treatment 2016 Wahl M, Descovich M, Shugard E, Pinnaduwage D, Sudhyadhom A, Chang A, Roach M, Gottschalk A, Chen J
• Long-term Outcomes Following Radiation Therapy For Prostate Cancer Patients With Lymph Node Metastases at Diagnosis Treated With and Without Surgery.
  American journal of clinical oncology 2016 Crehange G, Izaguirre A, Weinberg V, Hsu CC, Gottschalk AR, Hsu IC, Shinohara K, Carroll P, Roach M
• An Evaluation of Robotic and Conventional IMRT for Prostate Cancer: Potential for Dose Escalation.
  Technology in cancer research & treatment 2016 Pinnaduwage DS, Descovich M, Lometti MW, Varad B, Roach M, Gottschalk AR
• Outcomes of hypofractionated stereotactic body radiotherapy boost for intermediate and high-risk prostate cancer.
  Radiation oncology (London, England) 2016 Anwar M, Weinberg V, Seymour Z, Hsu IJ, Roach M, Gottschalk AR
• Arrhythmogenic effects of mutated L-type Ca 2+-channels on an optogenetically paced muscular pump in Caenorhabditis elegans.
  Scientific reports 2015 Schüler C, Fischer E, Shaltiel L, Steuer Costa W, Gottschalk A
• Investigating the clinical advantages of a robotic linac equipped with a multileaf collimator in the treatment of brain and prostate cancer patients.
  Journal of applied clinical medical physics 2015 McGuinness CM, Gottschalk AR, Lessard E, Nakamura JL, Pinnaduwage D, Pouliot J, Sims C, Descovich M
• Optogenetic manipulation of cGMP in cells and animals by the tightly light-regulated guanylyl-cyclase opsin CyclOp.
  Nature communications 2015 Gao S, Nagpal J, Schneider MW, Kozjak-Pavlovic V, Nagel G, Gottschalk A
• Intraoperative Radiotherapy in the Management of Locally Recurrent Extremity Soft Tissue Sarcoma.
  Sarcoma 2015 Tinkle CL, Weinberg V, Braunstein SE, Wustrack R, Horvai A, Jahan T, O'Donnell RJ, Gottschalk AR
• Patient- and treatment-specific predictors of genitourinary function after high-dose-rate monotherapy for favorable prostate cancer.
  Brachytherapy 2015 Raleigh DR, Chang AJ, Tomlin B, Cunha JA, Braunstein SE, Shinohara K, Gottschalk AR, Roach M, Hsu IC
• Obesity in regional anesthesia--a risk factor for peripheral catheter-related infections.
  Acta anaesthesiologica Scandinavica 2015 Bomberg H, Albert N, Schmitt K, Gräber S, Kessler P, Steinfeldt T, Hering W, Gottschalk A, Standl T, Stork J, Meißner W, Teßmann R, Geiger P, Koch T, Spies CD, Volk T, Kubulus C
• AzoCholine Enables Optical Control of Alpha 7 Nicotinic Acetylcholine Receptors in Neural Networks.
  ACS chemical neuroscience 2015 Damijonaitis A, Broichhagen J, Urushima T, Hüll K, Nagpal J, Laprell L, Schönberger M, Woodmansee DH, Rafiq A, Sumser MP, Kummer W, Gottschalk A, Trauner D
• Dose-volume analysis and the temporal nature of toxicity with stereotactic body radiation therapy for prostate cancer.
  Practical radiation oncology 2015 Seymour ZA, Chang AJ, Zhang L, Kirby N, Descovich M, Roach M, Hsu IC, Gottschalk AR
• Comparison between target margins derived from 4DCT scans and real-time tumor motion tracking: insights from lung tumor patients treated with robotic radiosurgery.
  Medical physics 2015 Descovich M, McGuinness C, Kannarunimit D, Chen J, Pinnaduwage D, Pouliot J, Kased N, Gottschalk AR, Yom SS
• Erratum: Synthetic retinal analogs modify the spectral and kinetic characteristics of microbial rhodopsin optogenetic tools.
  Nature communications 2015 AzimiHashemi N, Erbguth K, Vogt A, Riemensperger T, Rauch E, Woodmansee D, Nagpal J, Brauner M, Sheves M, Fiala A, Kattner L, Trauner D, Hegemann P, Gottschalk A, Liewald JF
• A consistent muscle activation strategy underlies crawling and swimming in Caenorhabditis elegans.
  Journal of the Royal Society, Interface 2015 Butler VJ, Branicky R, Yemini E, Liewald JF, Gottschalk A, Kerr RA, Chklovskii DB, Schafer WR
• Microbial Rhodopsin Optogenetic Tools: Application for Analyses of Synaptic Transmission and of Neuronal Network Activity in Behavior.
  Methods in molecular biology (Clifton, N.J.) 2015 Glock C, Nagpal J, Gottschalk A
• Synthetic retinal analogues modify the spectral and kinetic characteristics of microbial rhodopsin optogenetic tools.
  Nature communications 2014 AzimiHashemi N, Erbguth K, Vogt A, Riemensperger T, Rauch E, Woodmansee D, Nagpal J, Brauner M, Sheves M, Fiala A, Kattner L, Trauner D, Hegemann P, Gottschalk A, Liewald JF
• ACR appropriateness Criteria® Postradical prostatectomy irradiation in prostate cancer.
  Oncology (Williston Park, N.Y.) 2014 Gustafson GS, Nguyen PL, Assimos DG, D'Amico AV, Gottschalk AR, Hsu IC, Lloyd S, Mclaughlin PW, Merrick GS, Showalter TN, Taira AV, Vapiwala N, Yamada Y, Davis BJ
• Analysis of dose distribution and risk of pneumonitis in stereotactic body radiation therapy for centrally located lung tumors: a comparison of robotic radiosurgery, helical tomotherapy and volumetric modulated arc therapy.
  Technology in cancer research & treatment 2014 Kannarunimit D, Descovich M, Garcia A, Chen J, Weinberg V, Mcguinness C, Pinnaduwage D, Murnane J, Gottschalk AR, Yom SS
• [Differences of analgesic efficacy and complication rates between ultrasound and nervestimulator guided peripheral nerve catheters : Database analysis on patient-relevant target parameters].
  Der Anaesthesist 2014 Schnabel A, Middendorf B, Boschin MG, Gottschalk A, Van Aken H, Zahn PK, Pogatzki-Zahn EM
• Pre-plan parameters predict post-implant D90 ≥ 140 Gy for (125)I permanent prostate implants.
  Journal of contemporary brachytherapy 2014 Alexander J, Weinberg V, Gottschalk AR, Hsu IC, Shinohara K, Roach M
• ACR Appropriateness Criteria® Definitive External-Beam Irradiation in stage T1 and T2 prostate cancer.
  American journal of clinical oncology 2014 Nguyen PL, Aizer A, Assimos DG, D'Amico AV, Frank SJ, Gottschalk AR, Gustafson GS, Hsu IC, McLaughlin PW, Merrick G, Rosenthal SA, Showalter TN, Taira AV, Vapiwala N, Yamada Y, Davis BJ, American …
• Response to Drs Rogers, Hayes, and Demanes.
  Brachytherapy 2014 Hsu IC, Yamada Y, Assimos DG, D'Amico AV, Davis BJ, Frank SJ, Gottschalk AR, Gustafson GS, McLaughlin PW, Nguyen PL, Rosenthal SA, Taira AV, Vapiwala N, Merrick G, Expert Panel on Radiation Oncology–…
• Commentary on "A systematic review of stereotactic radiotherapy ablation for primary renal cell carcinoma." Siva S, Pham D, Gill S, Corcoran NM, Foroudi F. Division of Radiation Oncology and Cancer Imaging, Peter MacCallum Cancer Centre, Victoria, Australia.: BJU Int 2012;110(11 Pt B):E737-43. doi: 10.1111/j.1464-410X.2012.11550.x. [Epub 2012 Oct 29].
  Urologic oncology 2014 Gottschalk A
• Commentary on "Patient-reported outcomes after 3-dimensional conformal, intensity-modulated, or proton beam radiotherapy for localized prostate cancer." Gray PJ, Paly JJ, Yeap BY, Sanda MG, Sandler HM, Michalski JM, Talcott JA, Coen JJ, Hamstra DA, Shipley WU, Hahn SM, Zietman AL, Bekelman JE, Efstathiou JA. Harvard Radiation Oncology Program, Boston, MA.: Cancer 2013;119(9):1729-35. doi: 10.1002/cncr.27956. [Epub 2013 Feb 22].
  Urologic oncology 2014 Gottschalk A
• Commentary on "Toxicity after external beam radiotherapy for prostate cancer: an analysis of late morbidity in men with diabetes mellitus." Kalakota K, Liauw SL, Department of Radiation Oncology, Northwestern Memorial Hospital, Chicago, IL.: Urology 2013;81(6):1196-201. doi: 10.1016/j.urology.2013.01.047. [Epub 2013 Mar 26].
  Urologic oncology 2014 Gottschalk A
• The Long-Term Clinical Outcomes Following Autogenous Bone Grafting for Large-Volume Defects of the Knee: 12- to 21-Year Follow-Up.
  Cartilage 2014 Johnson LL, Delano M, Spector M, Pittsley A, Gottschalk A
• Endoscopic gold fiducial marker placement into the bladder wall to optimize radiotherapy targeting for bladder-preserving management of muscle-invasive bladder cancer: feasibility and initial outcomes.
  PloS one 2014 Garcia MM, Gottschalk AR, Brajtbord J, Konety BR, Meng MV, Roach M, Carroll PR
• Hypofractionated SBRT versus conventionally fractionated EBRT for prostate cancer: comparison of PSA slope and nadir.
  Radiation oncology (London, England) 2014 Anwar M, Weinberg V, Chang AJ, Hsu IC, Roach M, Gottschalk A
• Commentary on "secondary cancers after intensity-modulated radiotherapy, brachytherapy, and radical prostatectomy for the treatment of prostate cancer: incidence and cause-specific survival outcomes according to the initial treatment intervention." Zelefsky MJ, Pei X, Teslova T, Kuk D, Magsanoc JM, Kollmeier M, Cox B, Zhang Z. Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY.: BJU Int 2012;110:1696-701. doi: 10.1111/j.1464-410X.2012.11385.x. [Epub 2012 Aug 13].
  Urologic oncology 2014 Gottschalk A
• Evaluation of ray tracing and Monte Carlo algorithms in dose calculation and clinical outcomes for robotic stereotactic body radiotherapy of lung cancers.
  Journal of radiosurgery and SBRT 2014 Braunstein SE, Dionisio SA, Lometti MW, Pinnaduwage DS, Chuang CF, Yom SS, Gottschalk AR, Descovich M
• Photoactivated adenylyl cyclases as optogenetic modulators of neuronal activity.
  Methods in molecular biology (Clifton, N.J.) 2014 Costa WS, Liewald J, Gottschalk A
• ACR Appropriateness Criteria high-dose-rate brachytherapy for prostate cancer.
  Brachytherapy 2013 Hsu IC, Yamada Y, Assimos DG, D'Amico AV, Davis BJ, Frank SJ, Gottschalk AR, Gustafson GS, McLaughlin PW, Nguyen PL, Rosenthal SA, Taira AV, Vapiwala N, Merrick G
• Cold spot mapping inferred from MRI at time of failure predicts biopsy-proven local failure after permanent seed brachytherapy in prostate cancer patients: implications for focal salvage brachytherapy.
  Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2013 Crehange G, Krishnamurthy D, Cunha JA, Pickett B, Kurhanewicz J, Hsu IC, Gottschalk AR, Shinohara K, Roach M, Pouliot J
• Improving plan quality and consistency by standardization of dose constraints in prostate cancer patients treated with CyberKnife.
  Journal of applied clinical medical physics 2013 Descovich M, Carrara M, Morlino S, Pinnaduwage DS, Saltiel D, Pouliot J, Nash MB, Pignoli E, Valdagni R, Roach M, Gottschalk AR
• Sensory neuron fates are distinguished by a transcriptional switch that regulates dendrite branch stabilization.
  Neuron 2013 Smith CJ, O'Brien T, Chatzigeorgiou M, Spencer WC, Feingold-Link E, Husson SJ, Hori S, Mitani S, Gottschalk A, Schafer WR, Miller DM
• In vivo synaptic recovery following optogenetic hyperstimulation.
  Proceedings of the National Academy of Sciences of the United States of America 2013 Kittelmann M, Liewald JF, Hegermann J, Schultheis C, Brauner M, Steuer Costa W, Wabnig S, Eimer S, Gottschalk A
• Optogenetic manipulation of neural activity in C. elegans: from synapse to circuits and behaviour.
  Biology of the cell 2013 Husson SJ, Gottschalk A, Leifer AM
• Salvage HDR brachytherapy for recurrent prostate cancer after previous definitive radiation therapy: 5-year outcomes.
  International journal of radiation oncology, biology, physics 2013 Chen CP, Weinberg V, Shinohara K, Roach M, Nash M, Gottschalk A, Chang AJ, Hsu IC
• Keeping track of worm trackers.
  WormBook : the online review of C. elegans biology 2013 Husson SJ, Costa WS, Schmitt C, Gottschalk A
• ACR Appropriateness Criteria prostate cancer--pretreatment detection, staging, and surveillance.
  Journal of the American College of Radiology : JACR 2013 Eberhardt SC, Carter S, Casalino DD, Merrick G, Frank SJ, Gottschalk AR, Leyendecker JR, Nguyen PL, Oto A, Porter C, Remer EM, Rosenthal SA
• Computer-assisted, atlas-based segmentation for target volume delineation in whole pelvic IMRT for prostate cancer.
  Technology in cancer research & treatment 2012 Pejavar S, Yom SS, Hwang A, Speight J, Gottschalk A, Hsu IC, Roach M, Xia P
• Microbial light-activatable proton pumps as neuronal inhibitors to functionally dissect neuronal networks in C. elegans.
  PloS one 2012 Husson SJ, Liewald JF, Schultheis C, Stirman JN, Lu H, Gottschalk A
• Can regional anaesthesia for lymph-node dissection improve the prognosis in malignant melanoma?
  British journal of anaesthesia 2012 Gottschalk A, Brodner G, Van Aken HK, Ellger B, Althaus S, Schulze HJ
• Feasibility of MR imaging/MR spectroscopy-planned focal partial salvage permanent prostate implant (PPI) for localized recurrence after initial PPI for prostate cancer.
  International journal of radiation oncology, biology, physics 2012 Hsu CC, Hsu H, Pickett B, Crehange G, Hsu IC, Dea R, Weinberg V, Gottschalk AR, Kurhanewicz J, Shinohara K, Roach M
• Optogenetic analysis of a nociceptor neuron and network reveals ion channels acting downstream of primary sensors.
  Current biology : CB 2012 Husson SJ, Costa WS, Wabnig S, Stirman JN, Watson JD, Spencer WC, Akerboom J, Looger LL, Treinin M, Miller DM, Lu H, Gottschalk A
• Temporal compartmental dosing effects for robotic prostate stereotactic body radiotherapy.
  Physics in medicine and biology 2011 Shiao SL, Sahgal A, Hu W, Jabbari S, Chuang C, Descovich M, Hsu IC, Gottschalk AR, Roach M, Ma L
• Caenorhabditis elegans selects distinct crawling and swimming gaits via dopamine and serotonin.
  Proceedings of the National Academy of Sciences of the United States of America 2011 Vidal-Gadea A, Topper S, Young L, Crisp A, Kressin L, Elbel E, Maples T, Brauner M, Erbguth K, Axelrod A, Gottschalk A, Siegel D, Pierce-Shimomura JT
• PACα--an optogenetic tool for in vivo manipulation of cellular cAMP levels, neurotransmitter release, and behavior in Caenorhabditis elegans.
  Journal of neurochemistry 2011 Weissenberger S, Schultheis C, Liewald JF, Erbguth K, Nagel G, Gottschalk A
• Real-time multimodal optical control of neurons and muscles in freely behaving Caenorhabditis elegans.
  Nature methods 2011 Stirman JN, Crane MM, Husson SJ, Wabnig S, Schultheis C, Gottschalk A, Lu H
• Stereotactic body radiotherapy as monotherapy or post-external beam radiotherapy boost for prostate cancer: technique, early toxicity, and PSA response.
  International journal of radiation oncology, biology, physics 2010 Jabbari S, Weinberg VK, Kaprealian T, Hsu IC, Ma L, Chuang C, Descovich M, Shiao S, Shinohara K, Roach M, Gottschalk AR
• Controversies in diagnosis of pulmonary embolism.
  Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2010 Stein PD, Sostman HD, Dalen JE, Bailey DL, Bajc M, Goldhaber SZ, Goodman LR, Gottschalk A, Hull RD, Matta F, Pistolesi M, Tapson VF, Weg JG, Wells PS, Woodard PK, Consensus Group
• High-dose-rate brachytherapy boost for prostate cancer: comparison of two different fractionation schemes.
  International journal of radiation oncology, biology, physics 2010 Kaprealian T, Weinberg V, Speight JL, Gottschalk AR, Roach M, Shinohara K, Hsu IC
• Patellar metastatic melanoma in a 13-year-old boy.
  American journal of orthopedics (Belle Mead, N.J.) 2010 Burk TF, Horvai AE, Gottschalk AR, Leong SP, Kashani-Sabet M, Goldsby RE, Law J, O'Donnell RJ
• Gadolinium-enhanced magnetic resonance angiography for pulmonary embolism: a multicenter prospective study (PIOPED III).
  Annals of internal medicine 2010 Stein PD, Chenevert TL, Fowler SE, Goodman LR, Gottschalk A, Hales CA, Hull RD, Jablonski KA, Leeper KV, Naidich DP, Sak DJ, Sostman HD, Tapson VF, Weg JG, Woodard PK, PIOPED III (Prospective …
• Comparison of patient megavoltage cone beam CT images acquired with an unflattened beam from a carbon target and a flattened treatment beam.
  Medical physics 2010 Faddegon BA, Aubin M, Bani-Hashemi A, Gangadharan B, Gottschalk AR, Morin O, Sawkey D, Wu V, Yom SS
• A diamond target for megavoltage cone-beam CT.
  Medical physics 2010 Sawkey D, Lu M, Morin O, Aubin M, Yom SS, Gottschalk AR, Bani-Hashemi A, Faddegon BA
• Dose gradient near target-normal structure interface for nonisocentric CyberKnife and isocentric intensity-modulated body radiotherapy for prostate cancer.
  International journal of radiation oncology, biology, physics 2010 Hossain S, Xia P, Huang K, Descovich M, Chuang C, Gottschalk AR, Roach M, Ma L
• Equivalent biochemical control and improved prostate-specific antigen nadir after permanent prostate seed implant brachytherapy versus high-dose three-dimensional conformal radiotherapy and high-dose conformal proton beam radiotherapy boost.
  International journal of radiation oncology, biology, physics 2010 Jabbari S, Weinberg VK, Shinohara K, Speight JL, Gottschalk AR, Hsu IC, Pickett B, McLaughlin PW, Sandler HM, Roach M
• [Pain and quality of life for living donors after nephrectomy].
  Schmerz (Berlin, Germany) 2009 Gottschalk A, Götz J, Zenz M
• Nonrandom intrafraction target motions and general strategy for correction of spine stereotactic body radiotherapy.
  International journal of radiation oncology, biology, physics 2009 Ma L, Sahgal A, Hossain S, Chuang C, Descovich M, Huang K, Gottschalk A, Larson DA
• High-dose-rate brachytherapy for localized prostate adenocarcinoma post abdominoperineal resection of the rectum and pelvic irradiation: Technique and experience.
  Brachytherapy 2009 Jabbari S, Hsu IC, Kawakami J, Weinberg VK, Speight JL, Gottschalk AR, Roach M, Shinohara K
• Dose recalculation and the Dose-Guided Radiation Therapy (DGRT) process using megavoltage cone-beam CT.
  International journal of radiation oncology, biology, physics 2009 Cheung J, Aubry JF, Yom SS, Gottschalk AR, Celi JC, Pouliot J
• Salvage permanent perineal radioactive-seed implantation for treating recurrence of localized prostate adenocarcinoma after external beam radiotherapy.
  BJU international 2009 Aaronson DS, Yamasaki I, Gottschalk A, Speight J, Hsu IC, Pickett B, Roach M, Shinohara K
• Correction of megavoltage cone-beam CT images of the pelvic region based on phantom measurements for dose calculation purposes.
  Journal of applied clinical medical physics 2009 Aubry JF, Cheung J, Morin O, Gottschalk A, Beaulieu L, Pouliot J
• Intestinal signaling to GABAergic neurons regulates a rhythmic behavior in Caenorhabditis elegans.
  Proceedings of the National Academy of Sciences of the United States of America 2008 Mahoney TR, Luo S, Round EK, Brauner M, Gottschalk A, Thomas JH, Nonet ML
• Simulated real time image guided intrafraction tracking-delivery for hypofractionated prostate IMRT.
  Medical physics 2008 Hossain S, Xia P, Chuang C, Verhey L, Gottschalk AR, Mu G, Ma L
• Sci-Thurs PM: Delivery-12: Correction and calibration of megavoltage cone-beam CT images for the calculation of the dose of the day.
  Medical physics 2008 Aubry JF, Cheung J, Yom S, Gottschalk A, Aubin M, Morin O, Descovich M, Beaulieu L, Pouliot J
• Proposed rectal dose constraints for patients undergoing definitive whole pelvic radiotherapy for clinically localized prostate cancer.
  International journal of radiation oncology, biology, physics 2008 Chan LW, Xia P, Gottschalk AR, Akazawa M, Scala M, Pickett B, Hsu IC, Speight J, Roach M
• Clinical characteristics of patients with acute pulmonary embolism: data from PIOPED II.
  The American journal of medicine 2007 Stein PD, Beemath A, Matta F, Weg JG, Yusen RD, Hales CA, Hull RD, Leeper KV, Sostman HD, Tapson VF, Buckley JD, Gottschalk A, Goodman LR, Wakefied TW, Woodard PK
• Very low probability interpretation of V/Q lung scans in combination with low probability objective clinical assessment reliably excludes pulmonary embolism: data from PIOPED II.
  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2007 Gottschalk A, Stein PD, Sostman HD, Matta F, Beemath A
• Patient dose considerations for routine megavoltage cone-beam CT imaging.
  Medical physics 2007 Morin O, Gillis A, Descovich M, Chen J, Aubin M, Aubry JF, Chen H, Gottschalk AR, Xia P, Pouliot J
• Usefulness of multidetector spiral computed tomography according to age and gender for diagnosis of acute pulmonary embolism.
  The American journal of cardiology 2007 Stein PD, Beemath A, Quinn DA, Olson RE, Goodman LR, Gottschalk A, Hales CA, Hull RD, Leeper KV, Sostman HD, Weg JG, Woodard PK
• Daily electronic portal imaging of implanted gold seed fiducials in patients undergoing radiotherapy after radical prostatectomy.
  International journal of radiation oncology, biology, physics 2007 Schiffner DC, Gottschalk AR, Lometti M, Aubin M, Pouliot J, Speight J, Hsu IC, Shinohara K, Roach M
• Diagnostic pathways in acute pulmonary embolism: recommendations of the PIOPED II Investigators.
  Radiology 2007 Stein PD, Woodard PK, Weg JG, Wakefield TW, Tapson VF, Sostman HD, Sos TA, Quinn DA, Leeper KV, Hull RD, Hales CA, Gottschalk A, Goodman LR, Fowler SE, Buckley JD, PIOPED II Investigators
• Feasibility of high-dose-rate brachytherapy salvage for local prostate cancer recurrence after radiotherapy: the University of California-San Francisco experience.
  International journal of radiation oncology, biology, physics 2006 Lee B, Shinohara K, Weinberg V, Gottschalk AR, Pouliot J, Roach M, Hsu IC
• Comparative study of different concentrations of prilocaine and ropivacaine for intraoperative axillary brachial plexus block.
  European journal of anaesthesiology 2006 Freitag M, Zbieranek K, Gottschalk A, Bubenheim M, Winter R, Tuszynski S, Standl TG
• Clinical outcomes of intraoperative radiation therapy for extremity sarcomas.
  Sarcoma 2006 Tran QN, Kim AC, Gottschalk AR, Wara WM, Phillips TL, O'donnell RJ, Weinberg V, Haas-Kogan DA
• Inhibition of phosphatidylinositol-3-kinase causes increased sensitivity to radiation through a PKB-dependent mechanism.
  International journal of radiation oncology, biology, physics 2005 Gottschalk AR, Doan A, Nakamura JL, Stokoe D, Haas-Kogan DA
• [Infratentorial progressive multifocal leukoencephalopathy in a patient with pulmonary sarcoidosis].
  RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 2005 Gottschalk A, Danz B, Völk M
• Management of isolated renal fossa recurrence following radical nephrectomy.
  The Journal of urology 2005 Master VA, Gottschalk AR, Kane C, Carroll PR
• Inhibition of phosphatidylinositol-3-kinase causes cell death through a protein kinase B (PKB)-dependent mechanism and growth arrest through a PKB-independent mechanism.
  International journal of radiation oncology, biology, physics 2005 Gottschalk AR, Doan A, Nakamura JL, Haas-Kogan DA, Stokoe D
• PKB/Akt mediates radiosensitization by the signaling inhibitor LY294002 in human malignant gliomas.
  Journal of neuro-oncology 2005 Nakamura JL, Karlsson A, Arvold ND, Gottschalk AR, Pieper RO, Stokoe D, Haas-Kogan DA
• Combined modality treatment with high-dose-rate brachytherapy boost for locally advanced prostate cancer.
  Brachytherapy 2005 Hsu IC, Cabrera AR, Weinberg V, Speight J, Gottschalk AR, Roach M, Shinohara K
• High-resolution dental magnetic resonance imaging of inferior alveolar nerve responses to the extraction of third molars.
  European radiology 2004 Kress B, Gottschalk A, Anders L, Stippich C, Palm F, Bähren W, Sartor K
• The use of hormonal therapy with radiotherapy for prostate cancer: analysis of prospective randomised trials.
  British journal of cancer 2004 Gottschalk AR, Roach M
• eat-2 and eat-18 are required for nicotinic neurotransmission in the Caenorhabditis elegans pharynx.
  Genetics 2004 McKay JP, Raizen DM, Gottschalk A, Schafer WR, Avery L
• Evaluation of ultrasound-based prostate localization for image-guided radiotherapy.
  International journal of radiation oncology, biology, physics 2003 Langen KM, Pouliot J, Anezinos C, Aubin M, Gottschalk AR, Hsu IC, Lowther D, Liu YM, Shinohara K, Verhey LJ, Weinberg V, Roach M
• Dysregulation of PTEN and protein kinase B is associated with glioma histology and patient survival.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2002 Ermoian RP, Furniss CS, Lamborn KR, Basila D, Berger MS, Gottschalk AR, Nicholas MK, Stokoe D, Haas-Kogan DA
• [The prognostic value of quantified MRI at an early stage of Bell's palsy].
  RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 2002 Kress BP, Griesbeck F, Efinger K, Gottschalk A, Nissen S, Goriup A, Solbach T, Kornhuber AW, Bähren W
• Bell's palsy: what is the prognostic value of measurements of signal intensity increases with contrast enhancement on MRI?
  Neuroradiology 2002 Kress BP, Griesbeck F, Efinger K, Solbach T, Gottschalk A, Kornhuber AW, Bähren W
• Chronic alcohol consumption and cerebral indices of oxidative stress: is there a link?
  Alcoholism, clinical and experimental research 2001 Götz ME, Janetzky B, Pohli S, Gottschalk A, Gsell W, Tatschner T, Ransmayr G, Leblhuber F, Gerlach M, Reichmann H, Riederer P, Böning J
• p27Kip1 is required for PTEN-induced G1 growth arrest.
  Cancer research 2001 Gottschalk AR, Basila D, Wong M, Dean NM, Brandts CH, Stokoe D, Haas-Kogan DA
• Loss of PTEN facilitates HIF-1-mediated gene expression.
  Genes & development 2000 Zundel W, Schindler C, Haas-Kogan D, Koong A, Kaper F, Chen E, Gottschalk AR, Ryan HE, Johnson RS, Jefferson AB, Stokoe D, Giaccia AJ
• Mapping of secondary somatosensory cortex activation induced by vibrational stimulation: an fMRI study.
  Brain research 1999 Maldjian JA, Gottschalk A, Patel RS, Pincus D, Detre JA, Alsop DC
• Anti-immunoglobulin-induced apoptosis in WEHI 231 cells involves the slow formation of ceramide from sphingomyelin and is blocked by bcl-XL.
  The Journal of biological chemistry 1997 Wiesner DA, Kilkus JP, Gottschalk AR, Quintáns J, Dawson G
• Elderly Patients With no Prior Cardiopulmonary Disease Show Ventilation/Perfusion Lung Scan Characteristics That Are Sensitive and Specific for Pulmonary Embolism.
  The American journal of geriatric cardiology 1996 Stein PD, Henry JW, Relyea B, Gottschalk A
• Pulmonary embolism among patients with a nearly normal ventilation/perfusion lung scan.
  Chest 1996 Henry JW, Stein PD, Gottschalk A, Raskob GE
• Small perfusion defects in suspected pulmonary embolism.
  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996 Stein PD, Henry JW, Gottschalk A
• Evaluation of individual criteria for low probability interpretation of ventilation-perfusion lung scans.
  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996 Stein PD, Relyea B, Gottschalk A
• Scintigraphic lung scans and clinical assessment in critically ill patients with suspected acute pulmonary embolism.
  Chest 1996 Henry JW, Stein PD, Gottschalk A, Relyea B, Leeper KV
• Apoptosis in B lymphocytes: the WEHI-231 perspective.
  Immunology and cell biology 1995 Gottschalk AR, Quintáns J
• Identification of immunosuppressant-induced apoptosis in a murine B-cell line and its prevention by bcl-x but not bcl-2.
  Proceedings of the National Academy of Sciences of the United States of America 1994 Gottschalk AR, Boise LH, Thompson CB, Quintáns J
• Critical review of ventilation/perfusion lung scans in acute pulmonary embolism.
  Progress in cardiovascular diseases 1994 Stein PD, Gottschalk A
• Mechanisms of ventilatory periodicities.
  Annals of biomedical engineering 1993 Pack AI, Gottschalk A
• Value of ventilation/perfusion scans versus perfusion scans alone in acute pulmonary embolism.
  The American journal of cardiology 1992 Stein PD, Terrin ML, Gottschalk A, Alavi A, Henry JW
• Correlation between oscillations in ventilation and frequency content of the electroencephalogram.
  Journal of applied physiology (Bethesda, Md. : 1985) 1992 Pack AI, Cola MF, Goldszmidt A, Ogilvie MD, Gottschalk A
• Diagnosis of acute pulmonary embolism in the elderly.
  Journal of the American College of Cardiology 1991 Stein PD, Gottschalk A, Saltzman HA, Terrin ML
• Usefulness of noninvasive diagnostic tools for diagnosis of acute pulmonary embolism in patients with a normal chest radiograph.
  The American journal of cardiology 1991 Stein PD, Alavi A, Gottschalk A, Hales CA, Saltzman HA, Vreim CE, Weg JG
• Serial radionuclide assessment of doxorubicin cardiotoxicity in cancer patients with abnormal baseline resting left ventricular performance.
  American heart journal 1983 Choi BW, Berger HJ, Schwartz PE, Alexander J, Wackers FJ, Gottschalk A, Zaret BL
• Tomographic gallium-67 citrate scanning. Useful new surveillance for metastatic melanoma.
  Annals of surgery 1983 Kirkwood JM, Myers JE, Vlock DR, Neumann R, Ariyan S, Gottschalk A, Hoffer P
• Tomographic gallium-67 citrate scanning: useful new surveillance for metastatic melanoma.
  Annals of internal medicine 1982 Kirkwood JM, Myers JE, Vlock DR, Neumann R, Ariyan S, Gottschalk A, Hoffer P
• Serial assessment of doxorubicin cardiotoxicity with quantitative radionuclide angiocardiography.
  The New England journal of medicine 1979 Alexander J, Dainiak N, Berger HJ, Goldman L, Johnstone D, Reduto L, Duffy T, Schwartz P, Gottschalk A, Zaret BL
• Scintigraphic evaluation of lymphoma: a comparative study of 67Ga-citrate and 111In-Bleomycin.
  Radiology 1977 Bekerman C, Moran EM, Hoffer PB, Hendrix RW, Gottschalk A
• The scintillation camera with diverging collimator: physical parameters and a clinical evaluation.
  Seminars in nuclear medicine 1971 Gottschalk A, Usher MS, Turner DA, Polcyn RE, Quinn JL
• A COMPARISON OF RESULTS OF BRAIN SCANNING USING GA68-EDTA AND THE POSITRON SCINTILLATION CAMERA, WITH HG203-NEOHYDRIN AND THE CONVENTIONAL FOCUSED COLLIMATOR SCANNER.
  Radiology 1965 GOTTSCHALK A, MCCORMACK KR, ADAMS JE, ANGER HO
• RELATIVE EFFICIENCY OF HIGH-LET RADIATION (BRAGG-PEAK LITHIUM IONS) ON NORMAL RABBIT SKIN, USING INTEGRAL DOSE AS A BASIS FOR COMPARISON.
  Nature 1964 D ANGIO GJ, LAWRENCE JH, GOTTSCHALK A, LYMAN J
• THE SENSITIVITY OF THE POSITRON SCINTILLATION CAMERA FOR DETECTING SIMULATED BRAIN TUMORS WITH GALLIUM 68-EDTA.
  The American journal of roentgenology, radium therapy, and nuclear medicine 1964 GOTTSCHALK A, ANGER HO