Alan Wu, PhD
Professor
Laboratory Medicine
School of Medicine

His particular area of interest is in cardiac biomarkers for acute cardiac diseases (troponin, B-type natriuretic peptide, and novel biomarkers of ACS and heart failure).

The toxicology laboratory has expertise and analytic equipment for quantitation of drugs and other small molecules in biological fluids. Using liquid chromatography (LC) /time-of-flight (TOF) mass spectrometry (MS), this laboratory is able to conduct unknown searches for chemicals in these samples based on high resolution molecular weight (2-5 ppm), enabling the assignment of precise molecular formula. The LC/TOF-MS is ideal for detection of unknown drugs, chemicals and specimens. Recently, this laboratory has expanded its services to include analysis of medications both pharmaceuticals and nutriceuticals (herbals) and street preparations for the presence of adulterants, contaminants, and supplements. Once tentatively identified, the toxicology laboratory has LC-tandem MS capability for quantitation in the pg/mL concentrations.

Dr. Wu is also chief of the clinical pharmacogenomics laboratory and offers a clinical service and clinical research in pharmacogenomic for genomic targets such as cytochrome p450 2D6, 2C9, 2C19, vitamin K receptor complex, UDP glucuronsyltransferase, kif-6, and HLA-B*5710, 1502, and 5801. These targets for important for certain therapeutic drugs such as tamoxifen, codeine, antidepressants, warfarin, clopidogrel, irinotecan, statins, abacavir, carbamazepine, phenytoin, and allopurinol, respectively.

• Diabetes Technology Meeting 2023.
  Journal of diabetes science and technology 2024 Tian T, Aaron RE, DuNova AY, Jendle JH, Kerr D, Cengiz E, Drincic A, Pickup JC, Chen KY, Schwartz N, Muchmore DB, Akturk HK, Levy CJ, Schmidt S, Bellazzi R, Wu AHB, Spanakis EK, Najafi B, Chase JG, …
• Large-Scale Scientific Study Led by a Professional Organization during the COVID-19 Pandemic: Operations, Best Practices, and Lessons Learned.
  The journal of applied laboratory medicine 2024 Ondracek CR, Melanson SEF, Doan L, Schulz KM, Kleinman S, Zhao Z, Kumanovics A, Wu AHB, Wiencek J, Meng QH, Apple FS, Koch D, Vesper H, Pokuah F, Bryksin J, Myers GL, Christenson RH, Zhang YV
• The Role of Artificial Intelligence for Providing Scientific Content for Laboratory Medicine.
  The journal of applied laboratory medicine 2024 Wu AHB, Jaffe AS, Peacock WF, Kavsak P, Greene D, Christenson RH
• Serum free light chains among twin siblings: is the kappa/lambda ratio genetically determined?
  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2024 Wu AHB, Wang CC
• Performance of Three Anti-SARS-CoV-2 Anti-S and One Anti-N Immunoassays for the Monitoring of Immune Status and Vaccine Response.
  Viruses 2024 Zhang YV, Kumanovics A, Wiencek J, Melanson SEF, Love T, Wu AHB, Zhao Z, Meng QH, Koch DD, Apple FS, Ondracek CR, Christenson RH
• A non-invasive 25-Gene PLNM-Score urine test for detection of prostate cancer pelvic lymph node metastasis.
  Prostate cancer and prostatic diseases 2024 Guo J, Gu L, Johnson H, Gu D, Lu Z, Luo B, Yuan Q, Zhang X, Xia T, Zeng Q, Wu AHB, Johnson A, Dizeyi N, Abrahamsson PA, Zhang H, Chen L, Xiao K, Zou C, Persson JL
• Emerging Biomarkers in the Laboratory and in Practice: A Novel Approach to Diagnosing Heart Failure in Diabetes.
  Journal of diabetes science and technology 2024 Aaron RE, Tian T, Fleming GA, Sacks DB, Januzzi JL, Pop-Busui R, Hashim IA, Wu AHB, Pandey A, Klonoff DC
• EVALUATING ULTRA-WIDEFIELD IMAGING UTILITY IN THE DETECTION OF TREATMENT-REQUIRING PERIPHERAL RETINAL TEARS AND HOLES.
  Retina (Philadelphia, Pa.) 2024 Khan M, Kovacs K, Guan I, Goldblatt N, Foulsham W, Wu A, Papakostas T, Gupta M, D'Amico DJ, Kiss S, Orlin A
• Untargeted High-Resolution Mass Spectrometry for Detection of Natural Products and Confiscated Powders and Pills.
  Methods in molecular biology (Clifton, N.J.) 2024 Beckerdite E, Wu AHB
• Validation of diagnostic coding for children's interstitial lung disease (chILD).
  Pediatric pulmonology 2023 Garagozlo K, Han JY, Worgall S, Thomas C, Wu A, Chang N, Gerber LM, Fiorino EK
• Results from Lung Cancer Screening Outreach Utilizing a Mobile CT Scanner in an Urban Area.
  Journal of the American College of Radiology : JACR 2023 Pua BB, O'Neill BC, Ortiz AK, Wu A, D'Angelo D, Cahill M, Groner LK
• Cocaine Use is Associated With Increased LVMI in Unstably Housed Women With Polysubstance Use.
  Substance abuse 2023 Ravi A, Vittinghoff E, Wu AHB, Suen LW, Coffin PO, Hsue P, Lynch KL, Win S, Kazi DS, Riley ED
• Comparison of liquid chromatography-high-resolution tandem mass spectrometry (MS2) and multi-stage mass spectrometry (MS3) for screening toxic natural products.
  Journal of mass spectrometry and advances in the clinical lab 2023 Luo RY, Comstock K, Ding C, Wu AHB, Lynch KL
• A Novel ELISA for the Quantification of Serum Levels of 2 Glycosylated Variants of Apolipoprotein J: Biomarkers for Myocardial Ischemia.
  The journal of applied laboratory medicine 2023 Fernández Encinas L, Lluch N, Wu AHB, Kaski JC, Badimon L, Cubedo J
• Changes in circulating ApoJ-Glyc levels in patients with suspected acute coronary syndrome: The EDICA trial.
  International journal of cardiology 2023 Kaski JC, Lluch N, Lopez-Sendon JL, Gorog DA, Antorrena-Miranda I, Avanzas P, Herrero Puente P, Sionis A, González-Juanatey JR, Íñiguez A, Cordero A, Ako E, Fernández-Avilés F, Atienza F, Recio-…
• Analytical Validation of a Laboratory-Developed Lung Nodule Risk Reclassifier Assay.
  The journal of applied laboratory medicine 2023 Vuong DQ, Yu H, Seger A, Carbonell L, Wu AHB
• Assessment of Adverse Reactions, Antibody Patterns, and 12-month Outcomes in the Mother-Infant Dyad After COVID-19 mRNA Vaccination in Pregnancy.
  JAMA network open 2023 Cassidy AG, Li L, Golan Y, Gay C, Lin CY, Jigmeddagva U, Chidboy MA, Ilala M, Buarpung S, Gonzalez VJ, Basilio E, Duck M, Murtha AP, Wu AHB, Lynch KL, Asiodu IV, Prahl MK, Gaw SL
• Using Biomarkers for Traumatic Brain Injury: Are There Lessons That Can Be Learned from Implementing Cardiac Troponin?
  Clinical chemistry 2023 Wu AHB
• Biomarkers for the Diagnosis of Heart Failure in People with Diabetes: A Consensus Report from Diabetes Technology Society.
  Progress in cardiovascular diseases 2023 Yeung AM, Huang J, Pandey A, Hashim IA, Kerr D, Pop-Busui R, Rhee CM, Shah VN, Bally L, Bayes-Genis A, Bee YM, Bergenstal R, Butler J, Fleming GA, Gilbert G, Greene SJ, Kosiborod MN, Leiter LA, …
• Predictive Value of ABCC2 and UGT1A1 Polymorphisms on Irinotecan-Related Toxicities in Patients with Cancer.
  Genetic testing and molecular biomarkers 2023 Aoullay Z, Smith A, Slaoui M, El Bouchikhi I, Ghazal H, Al Idrissi N, Meddah B, Lynch KL, Cherrah Y, Wu AHB
• T Cell Responses Correlate with Self-Reported Disease Severity and Neutralizing Antibody Responses Predict Protection against SARS-CoV-2 Breakthrough Infection.
  Viruses 2023 Zhao Z, Kumanovics A, Love T, Melanson SEF, Meng QH, Wu AHB, Wiencek J, Apple FS, Ondracek CR, Koch DD, Christenson RH, Zhang YV
• Multiple substance use and blood pressure in women experiencing homelessness.
  Addictive behaviors reports 2023 Suen LW, Vittinghoff E, Wu AHB, Ravi A, Coffin PO, Hsue P, Lynch KL, Kazi DS, Riley ED
• Detection of IgM, IgG, IgA and neutralizing antibody responses to SARS-CoV-2 infection and mRNA vaccination.
  Journal of medical microbiology 2023 Fleischmann CJ, Bulman CA, Yun C, Lynch KL, Wu AHB, Whitman JD
• Concentration of hs-Troponin in small cohort of transgender patients.
  Clinica chimica acta; international journal of clinical chemistry 2022 Boone S, Peacock WF, Wu AHB, Jaffe A, Christenson RH, Ettner FM, Dadkhah S
• Heparin Does Not Regulate Circulating Human PCSK9 (Proprotein Convertase Subtilisin-Kexin Type 9) in a General Population-Brief Report.
  Arteriosclerosis, thrombosis, and vascular biology 2022 Xia VQ, Ong CM, Zier LS, MacGregor JS, Wu AHB, Chorba JS
• Transient expression of antinuclear RNP-A antibodies in patients with acute COVID-19 infection.
  Journal of translational autoimmunity 2022 Zhou S, Kaul R, Lynch KL, Wu AHB, Walker RP
• Serum Free Light Chain Quantification Testing: Comparison of Two Methods for Disease Monitoring.
  The journal of applied laboratory medicine 2022 Singh G, Whitaker BM, Wu AHB, Xu H, Bollag RJ
• Impact of multiple substance use on circulating ST2, a biomarker of adverse cardiac remodelling, in women.
  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2022 Riley ED, Kazi DS, Coffin PO, Vittinghoff E, Wade AN, Bulfone TC, Lynch KL, Atai Z, Wu AHB
• Tolerance for three commonly administered COVID-19 vaccines by healthcare professionals.
  Frontiers in public health 2022 Melanson SEF, Zhao Z, Kumanovics A, Love T, Meng QH, Wu AHB, Apple F, Ondracek CR, Schulz KM, Wiencek JR, Koch D, Christenson R, Zhang YV
• Hospitalized Patients With COVID-19 Have Higher Plasma Aldosterone-Renin Ratio and Lower ACE Activity Than Controls.
  Journal of the Endocrine Society 2022 Parikh NI, Arowolo F, Durstenfeld MS, Nah G, Njoroge J, Vittinghoff E, Long CS, Ganz P, Pearce D, Hsue P, Wu AHS, Hajizadeh N, Liu KD, Lynch KL
• COVID-19 is Observed in Older Children During the Omicron Wave in New York City.
  The Journal of emergency medicine 2022 Narayanan N, Langer S, Acker KP, Rosenblatt SD, Simmons W, Wu A, Han JY, Abramson EL, Grinspan ZM, Levine DA
• Multicenter Assessment of Sturge-Weber Syndrome: A Retrospective Study of Variations in Care and Use of Natural History Data.
  Pediatric neurology 2022 Arnesen RA, Barbour KK, Wu A, Yozawitz EG, Nelson A, Wolf SM, McGoldrick PE, Basma N, Grinspan ZM
• Reduced Immune Response and Neutralizing Antibody Activity to the SARS-CoV-2 Vaccination in Patients with a History of Solid Organ Transplant.
  Laboratory medicine 2022 French D, Ong CM, Patel P, Zuk M, Wu AHB
• Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and infancy.
  Nature communications 2022 Prahl M, Golan Y, Cassidy AG, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin CY, Gonzalez VJ, Chidboy MA, Warrier L, Buarpung S, Murtha AP, Flaherman VJ, Greene WC, Wu AHB, Lynch KL, Rajan J,…
• Development and application of a High-Resolution mass spectrometry method for the detection of fentanyl analogs in urine and serum.
  Journal of mass spectrometry and advances in the clinical lab 2022 Zhang Y, Halifax JC, Tangsombatvisit C, Yun C, Pang S, Hooshfar S, Wu AHB, Lynch KL
• Indications for Hospitalization in Children with SARS-CoV-2 Infection during the Omicron Wave in New York City.
  Children (Basel, Switzerland) 2022 Acker KP, Levine DA, Varghese M, Nash KA, RoyChoudhury A, Abramson EL, Grinspan ZM, Simmons W, Wu A, Han JY
• Multiple substance use, inflammation and cardiac stretch in women living with HIV.
  Drug and alcohol dependence 2022 Riley ED, Kizer JR, Tien PC, Vittinghoff E, Lynch KL, Wu AHB, Coffin PO, Beck-Engeser G, Braun C, Hunt PW
• Increased Serum IgG Antibody, Avidity, and Surrogate Virus Neutralization Response after a Third Dose for the BNT162b2 mRNA Vaccine to SARS-CoV-2.
  The journal of applied laboratory medicine 2022 Wu AHB, Lynch KL
• Neutralizing antibody activity against SARS-CoV-2 variants in gestational age-matched mother-infant dyads after infection or vaccination.
  JCI insight 2022 Matsui Y, Li L, Prahl M, Cassidy AG, Ozarslan N, Golan Y, Gonzalez VJ, Lin CY, Jigmeddagva U, Chidboy MA, Montano M, Taha TY, Khalid MM, Sreekumar B, Hayashi JM, Chen PY, Kumar GR, Warrier L, Wu AH, …
• Evaluation of Neutralizing Antibodies against SARS-CoV-2 Variants after Infection and Vaccination Using a Multiplexed Surrogate Virus Neutralization Test.
  Clinical chemistry 2022 Lynch KL, Zhou S, Kaul R, Walker R, Wu AH
• Adequate Antibody Response to COVID-19 Vaccine in Patients with Monoclonal Gammopathies and Light Chain Amyloidosis.
  Laboratory medicine 2022 Wu AHB, Wang CC, Ong CM, Lynch KL
• Point of care CYP2C19 genotyping after percutaneous coronary intervention.
  The pharmacogenomics journal 2022 Baudhuin LM, Train LJ, Goodman SG, Lane GE, Lennon RJ, Mathew V, Murthy V, Nazif TM, So DYF, Sweeney JP, Wu AHB, Rihal CS, Farkouh ME, Pereira NL
• Evolution of biomarker research in autoimmunity conditions for health professionals and clinical practice.
  Progress in molecular biology and translational science 2022 Silverstein A, Dudaev A, Studneva M, Aitken J, Blokh S, Miller AD, Tanasova S, Rose N, Ryals J, Borchers C, Nordstrom A, Moiseyakh M, Herrera AS, Skomorohov N, Marshall T, Wu A, Cheng RH, Syzko K, …
• Development and preliminary validation of infrared spectroscopic device for transdermal assessment of elevated cardiac troponin.
  Communications medicine 2022 Titus J, Wu AHB, Biswal S, Burman A, Sengupta SP, Sengupta PP
• Establishment of a High-Resolution Liquid Chromatography-Mass Spectrometry Spectral Library for Screening Toxic Natural Products.
  Journal of analytical toxicology 2022 Luo YR, Goodnough R, Yun C, Wu AHB, Lynch KL
• Prognosis is worse with elevated cardiac troponin in nonacute coronary syndrome compared with acute coronary syndrome.
  Coronary artery disease 2022 Horiuchi Y, Wettersten N, Patel MP, Mueller C, Neath SX, Christenson RH, Morgenthaler NG, McCord J, Nowak RM, Vilke GM, Daniels LB, Hollander JE, Apple FS, Cannon CM, Nagurney JT, Schreiber D, …
• Rate of Serum SARS-CoV-2 Antibody Decline for Two mRNA Vaccines.
  The journal of applied laboratory medicine 2022 Wu AHB, Nguyen ED, Ong CM, Yun C, Lynch KL
• Warfarin Dosing in Patients With CYP2C9*5 Variant Alleles.
  Clinical pharmacology and therapeutics 2022 Lindley KJ, Limdi NA, Cavallari LH, Perera MA, Lenzini P, Johnson JA, Wu AHB, Ridker PM, King CR, Eby CS, Patel S, Shah SV, Beasley TM, Li J, Gage BF
• Development of an LC-MS/MS Method for Measurement of Irinotecan and Its Major Metabolites in Plasma: Technical Considerations.
  Laboratory medicine 2022 Aoullay Z, Van Wijk XMR, Yanhui M, Meddah B, Lynch KL, Cherrah Y, Wu AHB
• Pediatric Epilepsy Learning Healthcare System Quality of Life (PELHS-QOL-2): A novel health-related quality of life prompt for children with epilepsy.
  Epilepsia 2021 Shah PD, Yun M, Wu A, Arnesen RA, Storey M, Sokoloff M, Shellhaas RA, Turnage C, Axeen EJ, Goodkin HP, Patel AD, Wentzel E, Modi AC, Grinspan ZM
• Diagnostic Value of Nucleocapsid Protein in Blood for SARS-CoV-2 Infection.
  Clinical chemistry 2021 Zhang Y, Ong CM, Yun C, Mo W, Whitman JD, Lynch KL, Wu AHB
• Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and early infancy.
  Research square 2021 Prahl M, Golan Y, Cassidy AG, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin CY, Gonzalez VJ, Chidboy MA, Warrier L, Buarpung S, Murtha AP, Flaherman VJ, Greene WC, Wu AHB, Lynch KL, Rajan J,…
• Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and early infancy.
  medRxiv : the preprint server for health sciences 2021 Prahl M, Golan Y, Cassidy AG, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin CY, Gonzalez VJ, Chidboy MA, Warrier L, Buarpung S, Murtha AP, Flaherman VJ, Greene WC, Wu AHB, Lynch KL, Rajan J,…
• Serum iron concentrations in non-iron induced acute liver injury.
  Clinica chimica acta; international journal of clinical chemistry 2021 Mudan A, Lebin JA, Wu AHB, Livshits Z
• Long-term weight loss maintenance with obesity pharmacotherapy: A retrospective cohort study.
  Obesity science & practice 2021 Tchang BG, Aras M, Wu A, Aronne LJ, Shukla AP
• COVID-19 mRNA Vaccination in Lactation: Assessment of Adverse Events and Vaccine Related Antibodies in Mother-Infant Dyads.
  Frontiers in immunology 2021 Golan Y, Prahl M, Cassidy AG, Gay C, Wu AHB, Jigmeddagva U, Lin CY, Gonzalez VJ, Basilio E, Chidboy MA, Warrier L, Buarpung S, Li L, Murtha AP, Asiodu IV, Ahituv N, Flaherman VJ, Gaw SL
• Effect of HIV-1 Infection on Angiopoietin 1 and 2 Levels and Measures of Microvascular and Macrovascular Endothelial Dysfunction.
  Journal of the American Heart Association 2021 Thakkar AB, Ma Y, Dela Cruz M, Wu Y, Arechiga V, Swaminathan S, Ganz P, Wu AHB, Scherzer R, Deeks S, Hsue PY
• Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibody Avidity Maturation and Association with Disease Severity.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2021 Luo YR, Chakraborty I, Yun C, Wu AHB, Lynch KL
• Kappa/Lambda Ratio for Early Detection of Multiple Myeloma Relapse Using the Reference Change Value from Biological Variation Studies.
  The journal of applied laboratory medicine 2021 Wu AHB
• The Reference Range for the Anion Gap Is Dependent on the Instrument's Electrolyte Assay.
  The journal of applied laboratory medicine 2021 Wu AHB, Jankowski T, Zhang Y, Lynch KL
• COVID-19 mRNA Vaccination in Lactation: Assessment of adverse events and vaccine related antibodies in mother-infant dyads.
  medRxiv : the preprint server for health sciences 2021 Golan Y, Prahl M, Cassidy AG, Gay C, Wu AHB, Jigmeddagva U, Lin CY, Gonzalez VJ, Basilio E, Warrier L, Buarpung S, Li L, Murtha AP, Asiodu IV, Ahituv N, Flaherman VJ, Gaw SL
• Circulating miR-122 in patients with non-toxic acute acetaminophen ingestions.
  Clinical toxicology (Philadelphia, Pa.) 2021 Lebin JA, Mudan A, Zhang Y, Wu AHB, Smollin CG
• Non-invasive Urine Test for Molecular Classification of Clinical Significance in Newly Diagnosed Prostate Cancer Patients.
  Frontiers in medicine 2021 Guo J, Zhang X, Xia T, Johnson H, Feng X, Simoulis A, Wu AHB, Li F, Tan W, Johnson A, Dizeyi N, Abrahamsson PA, Kenner L, Xiao K, Zhang H, Chen L, Zou C, Persson JL
• Impact of duloxetine on male fertility: A randomised controlled clinical trial.
  Andrologia 2021 Punjani N, Kang C, Flannigan R, Bach P, Altemus M, Kocsis JH, Wu A, Pierce H, Schlegel PN
• Development and Evaluation of Computable Phenotypes in Pediatric Epilepsy:3 Cases.
  Journal of child neurology 2021 Pan S, Wu A, Weiner M, M Grinspan Z
• Passive and active immunity in infants born to mothers with SARS-CoV-2 infection during pregnancy: prospective cohort study.
  BMJ open 2021 Song D, Prahl M, Gaw SL, Narasimhan SR, Rai DS, Huang A, Flores CV, Lin CY, Jigmeddagva U, Wu A, Warrier L, Levan J, Nguyen CBT, Callaway P, Farrington L, Acevedo GR, Gonzalez VJ, Vaaben A, Nguyen P, …
• The Impact of Mass Spectrometry on Patients' Medical and Nonmedical Lives.
  Laboratory medicine 2021 Wu AHB
• A SARS-CoV-2 Label-Free Surrogate Virus Neutralization Test and a Longitudinal Study of Antibody Characteristics in COVID-19 Patients.
  Journal of clinical microbiology 2021 Luo YR, Yun C, Chakraborty I, Wu AHB, Lynch KL
• A combined assay for quantifying remdesivir and its metabolite, along with dexamethasone, in serum.
  The Journal of antimicrobial chemotherapy 2021 Reckers A, Wu AHB, Ong CM, Gandhi M, Metcalfe J, Gerona R
• Citywide serosurveillance of the initial SARS-CoV-2 outbreak in San Francisco using electronic health records.
  Nature communications 2021 Routledge I, Epstein A, Takahashi S, Janson O, Hakim J, Duarte E, Turcios K, Vinden J, Sujishi K, Rangel J, Coh M, Besana L, Ho WK, Oon CY, Ong CM, Yun C, Lynch K, Wu AHB, Wu W, Karlon W, Thornborrow …
• Reduced pre-analytical issues for measuring troponin with use of a high sensitivity assay.
  Clinical biochemistry 2021 Wu AHB
• Passive and active immunity in infants born to mothers with SARS-CoV-2 infection during pregnancy: Prospective cohort study.
  medRxiv : the preprint server for health sciences 2021 Song D, Prahl M, Gaw SL, Narasimhan S, Rai D, Huang A, Flores C, Lin CY, Jigmeddagva U, Wu AHB, Warrier L, Levan J, Nguyen CBT, Callaway P, Farrington L, Acevedo GR, Gonzalez VJ, Vaaben A, Nguyen P, …
• Return-to-Play Guidelines for Athletes After COVID-19 Infection.
  JAMA cardiology 2021 Greene DN, Wu AHB, Jaffe AS
• Lack of Cross-Reactivity of Tianeptine with Tricyclic Antidepressant Immunoassays.
  Journal of analytical toxicology 2021 Badea A, Ghosh R, Lynch KL, Wu AHB
• A 23-Gene Classifier urine test for prostate cancer prognosis.
  Clinical and translational medicine 2021 Guo J, Johnson H, Zhang X, Feng X, Zhang H, Simoulis A, Wu AH, Xia T, Li F, Tan W, Johnson A, Dizeyi N, Abrahamsson PA, Kenner L, Chen L, Zhong W, Xiao K, Persson JL, Zou C
• Characterization of Hemorrhagic and Ischemic Stroke in a Diverse Cohort of COVID-19 Patients.
  The Neurohospitalist 2021 Ramos AD, Koyfman F, Byrns K, Wu A, Yasen J, Elreda L, Boddu S, Pishanidar S, Allen B, Juthani RG
• Citywide serosurveillance of the initial SARS-CoV-2 outbreak in San Francisco.
  Research square 2021 Routledge I, Epstein A, Takahashi S, Janson O, Hakim J, Duarte E, Turcios K, Vinden J, Sujishi K, Rangel J, Coh M, Besana L, Ho WK, Oon CY, Ong CM, Yun C, Lynch K, Wu AHB, Wu W, Karlon W, Thornborrow …
• Magnitude and Kinetics of Anti-Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Responses and Their Relationship to Disease Severity.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2021 Lynch KL, Whitman JD, Lacanienta NP, Beckerdite EW, Kastner SA, Shy BR, Goldgof GM, Levine AG, Bapat SP, Stramer SL, Esensten JH, Hightower AW, Bern C, Wu AHB
• Cardiac Troponin Composition Characterization after Non ST-Elevation Myocardial Infarction: Relation with Culprit Artery, Ischemic Time Window, and Severity of Injury.
  Clinical chemistry 2021 Damen SAJ, Cramer GE, Dieker HJ, Gehlmann H, Ophuis TJMO, Aengevaeren WRM, Fokkert M, Verheugt FWA, Suryapranata H, Wu AH, van Wijk XMR, Brouwer MA
• Race and Genetic Ancestry in Medicine - A Time for Reckoning with Racism.
  The New England journal of medicine 2021 Borrell LN, Elhawary JR, Fuentes-Afflick E, Witonsky J, Bhakta N, Wu AHB, Bibbins-Domingo K, Rodríguez-Santana JR, Lenoir MA, Gavin JR, Kittles RA, Zaitlen NA, Wilkes DS, Powe NR, Ziv E, Burchard EG
• Spatiotemporal cellular movement and fate decisions during first pharyngeal arch morphogenesis.
  Science advances 2020 Yuan Y, Loh YE, Han X, Feng J, Ho TV, He J, Jing J, Groff K, Wu A, Chai Y
• Establishing a Urine-Based Biomarker Assay for Prostate Cancer Risk Stratification.
  Frontiers in cell and developmental biology 2020 Guo J, Liu D, Zhang X, Johnson H, Feng X, Zhang H, Wu AHB, Chen L, Fang J, Xiao Z, Xiao K, Persson JL, Zou C
• Development and validation of a 25-Gene Panel urine test for prostate cancer diagnosis and potential treatment follow-up.
  BMC medicine 2020 Johnson H, Guo J, Zhang X, Zhang H, Simoulis A, Wu AHB, Xia T, Li F, Tan W, Johnson A, Dizeyi N, Abrahamsson PA, Kenner L, Feng X, Zou C, Xiao K, Persson JL, Chen L
• Extracellular vesicles released in blood of COVID-19 patients: mechanism for detection of cardiac troponin after myocardial injury?
  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2020 Wu AHB, Zhang Y, Webber R
• Chronic alcohol use does not protect against COVID-19 infection.
  The American journal of emergency medicine 2020 Lebin JA, Mudan A, Wu AHB
• Development of Label-Free Immunoassays as Novel Solutions for the Measurement of Monoclonal Antibody Drugs and Antidrug Antibodies.
  Clinical chemistry 2020 Luo YR, Chakraborty I, Lazar-Molnar E, Wu AHB, Lynch KL
• 99th Percentile Upper-Reference Limit of Cardiac Troponin and the Diagnosis of Acute Myocardial Infarction.
  Clinical chemistry 2020 Sandoval Y, Apple FS, Saenger AK, Collinson PO, Wu AHB, Jaffe AS
• Lot-to-Lot Variation for Commercial High-Sensitivity Cardiac Troponin: Can We Realistically Report Down to the Assay's Limit of Detection?
  Clinical chemistry 2020 Wu AHB, Kavsak PA, Aakre KM, Christenson RH, Greene DN, Apple FS, Peacock WF, Hollander JE, de Lemos JA, Morrow D, Januzzi J, Jaffe AS
• Screening the General Population for SARS-CoV-2 Virus and COVID-19 Antibodies: A Counterargument.
  The journal of applied laboratory medicine 2020 Wu AHB
• Impact of polysubstance use on high-sensitivity cardiac troponin I over time in homeless and unstably housed women.
  Drug and alcohol dependence 2020 Riley ED, Vittinghoff E, Wu AHB, Coffin PO, Hsue PY, Kazi DS, Wade A, Braun C, Lynch KL
• Evaluation of SARS-CoV-2 serology assays reveals a range of test performance.
  Nature biotechnology 2020 Whitman JD, Hiatt J, Mowery CT, Shy BR, Yu R, Yamamoto TN, Rathore U, Goldgof GM, Whitty C, Woo JM, Gallman AE, Miller TE, Levine AG, Nguyen DN, Bapat SP, Balcerek J, Bylsma SA, Lyons AM, Li S, Wong …
• Biomarkers Enhance Discrimination and Prognosis of Type 2 Myocardial Infarction.
  Circulation 2020 Horiuchi Y, Wettersten N, Patel MP, Mueller C, Neath SX, Christenson RH, Morgenthaler NG, McCord J, Nowak RM, Vilke GM, Daniels LB, Hollander JE, Apple FS, Cannon CM, Nagurney JT, Schreiber D, …
• Retinopathy in adults with hypertension and diabetes mellitus in Western Tanzania: a cross-sectional study.
  Tropical medicine & international health : TM & IH 2020 Woodward R, Mgaya E, Mwanansao C, Peck RN, Wu A, Sun G
• Magnitude and kinetics of anti-SARS-CoV-2 antibody responses and their relationship to disease severity.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2020 Lynch KL, Whitman JD, Lacanienta NP, Beckerdite EW, Kastner SA, Shy BR, Goldgof GM, Levine AG, Bapat SP, Stramer SL, Esensten JH, Hightower AW, Bern C, Wu AHB
• A Multicenter Evaluation of a Nongel Mechanical Separator Plasma Blood Collection Tube for Testing of Selected Therapeutic Drugs.
  The journal of applied laboratory medicine 2020 Morosyuk S, Berube J, Christenson R, Wu AHB, Uettwiller-Geiger D, Palicka V, Prusa R, Zima T, Shaw K, Plokhoy E, Ahuja AJ, Stankovic AK
• Analytical performance of cardiac troponin assays - Current status and future needs.
  Clinica chimica acta; international journal of clinical chemistry 2020 Aakre KM, Saeed N, Wu AHB, Kavsak PA
• A survey-based study of physician practices regarding biotin supplementation.
  The Journal of dermatological treatment 2020 Waqas B, Wu A, Yim E, Lipner SR
• cBIN1 Score (CS) Identifies Ambulatory HFrEF Patients and Predicts Cardiovascular Events.
  Frontiers in physiology 2020 Hitzeman TC, Xie Y, Zadikany RH, Nikolova AP, Baum R, Caldaruse AM, Agvanian S, Melmed GY, McGovern DPB, Geft DR, Chang DH, Moriguchi JD, Hage A, Azarbal B, Czer LS, Kittleson MM, Patel JK, Wu AHB, …
• Upper reference limits and percent measurable concentrations using a universal sample bank for high sensitivity cardiac troponin I using a point-of-care assay.
  Clinical biochemistry 2020 Wu AHB, Lynch K, Sexter A, Apple FS
• Test performance evaluation of SARS-CoV-2 serological assays.
  medRxiv : the preprint server for health sciences 2020 Whitman JD, Hiatt J, Mowery CT, Shy BR, Yu R, Yamamoto TN, Rathore U, Goldgof GM, Whitty C, Woo JM, Gallman AE, Miller TE, Levine AG, Nguyen DN, Bapat SP, Balcerek J, Bylsma SA, Lyons AM, Li S, Wong …
• Myocardial Infarction Can Be Safely Excluded by High-sensitivity Troponin I Testing 3 Hours After Emergency Department Presentation.
  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2020 Peacock WF, Christenson R, Diercks DB, Fromm C, Headden GF, Hogan CJ, Kulstad EB, LoVecchio F, Nowak RM, Schrock JW, Singer AJ, Storrow AB, Straseski J, Wu AHB, Zelinski DP
• Sex-Specific 99th Percentile Upper Reference Limits for High Sensitivity Cardiac Troponin Assays Derived Using a Universal Sample Bank.
  Clinical chemistry 2020 Apple FS, Wu AHB, Sandoval Y, Sexter A, Love SA, Myers G, Schulz K, Duh SH, Christenson RH
• MicroRNA-19b predicts widespread pain and posttraumatic stress symptom risk in a sex-dependent manner following trauma exposure.
  Pain 2020 Linnstaedt SD, Rueckeis CA, Riker KD, Pan Y, Wu A, Yu S, Wanstrath B, Gonzalez M, Harmon E, Green P, Chen CV, King T, Lewandowski C, Hendry PL, Pearson C, Kurz MC, Datner E, Velilla MA, Domeier R, …
• A thin-film interferometry-based label-free immunoassay for the detection of daratumumab interference in serum protein electrophoresis.
  Clinica chimica acta; international journal of clinical chemistry 2019 Luo YR, Chakraborty I, Zuk RF, Lynch KL, Wu AHB
• Ultrasensitive Detection of Clostridioides difficile Toxins in Stool by Use of Single-Molecule Counting Technology: Comparison with Detection of Free Toxin by Cell Culture Cytotoxicity Neutralization Assay.
  Journal of clinical microbiology 2019 Hansen G, Young S, Wu AHB, Herding E, Nordberg V, Mills R, Griego-Fullbright C, Wagner A, Ong CM, Lewis S, Yoon J, Estis J, Sandlund J, Friedland E, Carroll KC
• Narrowed reference intervals for complete blood count in a multiethnic population.
  Clinical chemistry and laboratory medicine 2019 Lee S, Ong CM, Zhang Y, Wu AHB
• Cardiac troponin I is present in plasma of type 1 myocardial infarction patients and patients with troponin I elevations due to other etiologies as complex with little free I.
  Clinical biochemistry 2019 van Wijk XMR, Claassen S, Enea NS, Li P, Yang S, Brouwer MA, Cramer GE, Zuk R, Lynch KL, Wu AHB
• "On Vivo" and Wearable Clinical Laboratory Testing Devices for Emergency and Critical Care Laboratory Testing.
  The journal of applied laboratory medicine 2019 Wu AHB
• The biological variation of plasma proenkephalin: data from a stable heart failure cohort.
  Clinical chemistry and laboratory medicine 2019 Wu AHB, Anand I
• A Liquid-Chromatography High-Resolution Mass Spectrometry Method for Non-FDA Approved Benzodiazepines.
  Journal of analytical toxicology 2019 van Wijk XMR, Yun C, Hooshfar S, Arens AM, Lung D, Wu AHB, Lynch KL
• Serum 25-Hydroxyvitamin D Concentrations from Patient Groups at High Risk for Deficiency.
  The journal of applied laboratory medicine 2019 Wu AHB, Ghosh R, Mei Ong C, French D
• XW-100: First FDA CLIA-Waived CBC Analyzer Designed for Physician Office Use.
  The journal of applied laboratory medicine 2019 Wu AHB, Sellers J
• Analytical and clinical concordance of free light chain assay.
  Practical laboratory medicine 2018 Smith A, Wu AHB
• Association of a Novel Diagnostic Biomarker, the Plasma Cardiac Bridging Integrator 1 Score, With Heart Failure With Preserved Ejection Fraction and Cardiovascular Hospitalization.
  JAMA cardiology 2018 Nikolova AP, Hitzeman TC, Baum R, Caldaruse AM, Agvanian S, Xie Y, Geft DR, Chang DH, Moriguchi JD, Hage A, Azarbal B, Czer LS, Kittleson MM, Patel JK, Wu AHB, Kobashigawa JA, Hamilton M, Hong T, Shaw…
• Analytical validation of a novel multi-analyte plasma test for lung nodule characterization.
  Biomedical research and reviews 2018 Trivedi NN, Brown JK, Rubenstein T, Rostykus AD, Fish AL, Yu H, Carbonell L, Juang A, Kamer S, Patel B, Sidhu M, Vuong D, Wang S, Beggs M, Wu AH, Arjomandi M
• Risk assessment for indeterminate pulmonary nodules using a novel, plasma-protein based biomarker assay.
  Biomedical research and clinical practice 2018 Trivedi NN, Arjomandi M, Brown JK, Rubenstein T, Rostykus AD, Esposito S, Axler E, Beggs M, Yu H, Carbonell L, Juang A, Kamer S, Patel B, Wang S, Fish AL, Haddad Z, Wu AH
• Grape skin extract improves muscle function and extends lifespan of a Drosophila model of Parkinson's disease through activation of mitophagy.
  Experimental gerontology 2018 Wu Z, Wu A, Dong J, Sigears A, Lu B
• Multicenter assessment of a hemoglobin A1c point-of-care device for diagnosis of diabetes mellitus.
  Clinical biochemistry 2018 Sobolesky PM, Smith BE, Saenger AK, Schulz K, Apple FS, Scott MG, Wu AHB, Little RR, Fitzgerald RL
• The SLE-key test serological signature: new insights into the course of lupus.
  Rheumatology (Oxford, England) 2018 Putterman C, Pisetsky DS, Petri M, Caricchio R, Wu AHB, Sanz I, Oates JC, Wallace S, Sorek R, Gerwien R, Safer P, Jakobi-Brook K, Cohen IR
• Quality Control Practices for Chemistry and Immunochemistry in a Cohort of 21 Large Academic Medical Centers.
  American journal of clinical pathology 2018 Rosenbaum MW, Flood JG, Melanson SEF, Baumann NA, Marzinke MA, Rai AJ, Hayden J, Wu AHB, Ladror M, Lifshitz MS, Scott MG, Peck-Palmer OM, Bowen R, Babic N, Sobhani K, Giacherio D, Bocsi GT, Herman DS,…
• Detecting Infections Rapidly and Easily for Candidemia Trial, Part 2 (DIRECT2): A Prospective, Multicenter Study of the T2Candida Panel.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2018 Clancy CJ, Pappas PG, Vazquez J, Judson MA, Kontoyiannis DP, Thompson GR, Garey KW, Reboli A, Greenberg RN, Apewokin S, Lyon GM, Ostrosky-Zeichner L, Wu AHB, Tobin E, Nguyen MH, Caliendo AM
• Copeptin to rule out myocardial infarction in Blacks versus Caucasians.
  European heart journal. Acute cardiovascular care 2018 Beri N, Daniels LB, Jaffe A, Mueller C, Anand I, Peacock WF, Hollander JE, DeFilippi C, Schreiber D, McCord J, Limkakeng AT, Wu AHB, Apple FS, Diercks DB, Nagurney JT, Nowak RM, Cannon CM, Clopton P, …
• The influence of pharmacogenomics on the protective effect of light-to-moderate alcohol use.
  Personalized medicine 2018 Wu AH
• Evaluation of Intraosseous Fluid as an Alternative Biological Specimen in Postmortem Toxicology.
  Journal of analytical toxicology 2018 Rodda LN, Volk JA, Moffat E, Williams CM, Lynch KL, Wu AHB
• Quantitation of Infliximab and Detection of Antidrug Antibodies in Serum by Use of Surface Plasmon Resonance.
  The journal of applied laboratory medicine 2018 Thoren KL, Pasi B, Delgado JC, Wu AHB, Lynch KL
• Quantitative Analysis of Immune Infiltrates in Primary Melanoma.
  Cancer immunology research 2018 Gartrell RD, Marks DK, Hart TD, Li G, Davari DR, Wu A, Blake Z, Lu Y, Askin KN, Monod A, Esancy CL, Stack EC, Jia DT, Armenta PM, Fu Y, Izaki D, Taback B, Rabadan R, Kaufman HL, Drake CG, Horst BA, …
• Pharmacogenomic-guided dosing for warfarin: too little too late?
  Personalized medicine 2018 Wu AH
• Clinical Laboratory Practice Recommendations for the Use of Cardiac Troponin in Acute Coronary Syndrome: Expert Opinion from the Academy of the American Association for Clinical Chemistry and the Task Force on Clinical Applications of Cardiac Bio-Markers of the International Federation of Clinical Chemistry and Laboratory Medicine.
  Clinical chemistry 2018 Wu AHB, Christenson RH, Greene DN, Jaffe AS, Kavsak PA, Ordonez-Llanos J, Apple FS
• AACC Academy's Pain Management LMPG: Verification of Drug Dosing with Quantitative Urine Drug Testing?
  The journal of applied laboratory medicine 2018 Wu AHB
• Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles.
  Journal of visualized experiments : JoVE 2017 Madasamy S, Liu D, Lundry J, Alderete B, Kong R, Robinson JP, Wu AHB, Amento EP
• Cannabis Intoxication Case Series: The Dangers of Edibles Containing Tetrahydrocannabinol.
  Annals of emergency medicine 2017 Vo KT, Horng H, Li K, Ho RY, Wu AHB, Lynch KL, Smollin CG
• Emergence of carbapenem-resistant hypervirulent Klebsiella pneumoniae.
  The Lancet. Infectious diseases 2017 Wong MHY, Shum HP, Chen JHK, Man MY, Wu A, Chan EW, Yuen KY, Chen S
• Proenkephalin (PENK) as a Novel Biomarker for Kidney Function.
  The journal of applied laboratory medicine 2017 Beunders R, Struck J, Wu AHB, Zarbock A, Di Somma S, Mehta RL, Koyner JL, Nadim MK, Maisel AS, Murray PT, Neath SX, Jaffe A, Pickkers P
• CD4 Lymphocyte Enumeration and Hemoglobin Assessment Aid for Priority Decisions: A Multisite Evaluation of the BD FACSPresto™ System.
  The open AIDS journal 2017 Thakar M, Angira F, Pattanapanyasat K, Wu AHB, O'Gorman M, Zeng H, Qu C, Mahajan B, Sukapirom K, Chen D, Hao Y, Gong Y, Indig MA, Graminske S, Orta D, d'Empaire N, Lu B, Omana-Zapata I, Zeh C
• Comprehensive Age and Sex 99th Percentiles for a High-Sensitivity Cardiac Troponin I Assay.
  Clinical chemistry 2017 Estis J, Wu AHB, Todd J, Bishop J, Sandlund J, Kavsak PA
• Heterogeneous drug penetrance of veliparib and carboplatin measured in triple negative breast tumors.
  Breast cancer research : BCR 2017 Bartelink IH, Prideaux B, Krings G, Wilmes L, Lee PRE, Bo P, Hann B, Coppé JP, Heditsian D, Swigart-Brown L, Jones EF, Magnitsky S, Keizer RJ, de Vries N, Rosing H, Pawlowska N, Thomas S, Dhawan M, …
• The Era for High-Sensitivity Cardiac Troponin Has Begun in the US (Finally).
  The journal of applied laboratory medicine 2017 Wu AHB, Christenson R
• A case of severe empyema with acute respiratory distress syndrome caused by Slackia exigua requiring veno-venous extracorporeal membrane oxygenation.
  Anaerobe 2017 Man MY, Shum HP, Wu A, Lee RA, Yan WW
• Clinical utility of single molecule counting technology for quantification of KIM-1 in patients with heart failure and chronic kidney disease.
  Clinical biochemistry 2017 Miao J, Friedman E, Wu AHB, Todd JA, Estis J, Xu X, Nolan N, Bishop JJ, Lenihan DJ
• Creation of a Universal Sample Bank for Determining the 99th Percentile for Cardiac Troponin Assays.
  The journal of applied laboratory medicine 2017 Wu AHB, Apple F, Love SA, Koch D, Myers GL, Christenson RH, AACC's Biomarkers of Acute Cardiovascular Disease Division
• Pioneers in Clinical Chemistry: George N. Bowers, Jr., MD, and Robert B. McComb, PhD.
  The journal of applied laboratory medicine 2017 Burnett RW, Ladenson JH, Wu AHB, Moore R
• The Association of Five-Year Changes in the Levels of N-Terminal Fragment of the Prohormone Brain-Type Natriuretic Peptide (NT-proBNP) with Subsequent Heart Failure and Death in Patients with Stable Coronary Artery Disease: The Heart and Soul Study.
  Cardiology 2017 Mishra RK, Judson G, Christenson RH, DeFilippi C, Wu AHB, Whooley MA
• Anticholinergic toxicity associated with ingestion of water containing lupini bean extract.
  Clinical toxicology (Philadelphia, Pa.) 2017 Li K, van Wijk XMR, Hayashi S, Lynch KL, Wu AHB, Smollin CG
• Cocaine use is associated with a higher prevalence of elevated ST2 concentrations.
  Clinical biochemistry 2017 van Wijk XMR, Vittinghoff E, Wu AHB, Lynch KL, Riley ED
• Total Analytic Error for Low Cardiac Troponin Concentrations (≤10 ng/L) by Use of a High-Sensitivity Cardiac Troponin Assay.
  Clinical chemistry 2017 Kavsak PA, Jaffe AS, Greene DN, Christenson RH, Apple FS, Wu AHB
• Higher prevalence of detectable troponin I among cocaine-users without known cardiovascular disease.
  Drug and alcohol dependence 2017 Riley ED, Hsue PY, Vittinghoff E, Wu AH, Coffin PO, Moore PK, Lynch KL
• Personalized justice: the potential use of genotyping in wrongful death investigations.
  Personalized medicine 2016 Wu AH
• Necessity of hospitalization and stress testing in low risk chest pain patients.
  The American journal of emergency medicine 2016 Beri N, Marston NA, Daniels LB, Nowak RM, Schreiber D, Mueller C, Jaffe A, Diercks DB, Wettersten N, DeFilippi C, Peacock WF, Limkakeng AT, Anand I, McCord J, Hollander JE, Wu AHB, Apple FS, Nagurney …
• Variability of biomarkers in patients with chronic heart failure and healthy controls.
  European journal of heart failure 2016 Meijers WC, van der Velde AR, Muller Kobold AC, Dijck-Brouwer J, Wu AH, Jaffe A, de Boer RA
• Synthetic agents off the darknet: a case of U-47700 and phenazepam abuse.
  Clinical toxicology (Philadelphia, Pa.) 2016 Vo KT, van Wijk XM, Wu AH, Lynch KL, Ho RY
• A comparison of methods for evaluation of a case of suspected macro-aspartate aminotransferase.
  Clinica chimica acta; international journal of clinical chemistry 2016 van Wijk XMR, Magee CA, Wu AHB, Tana MM, Lynch KL
• Adverse Effects From Counterfeit Alprazolam Tablets.
  JAMA internal medicine 2016 Arens AM, van Wijk XM, Vo KT, Lynch KL, Wu AH, Smollin CG
• Nonenzymatic Mechanism of Statins in Modulating Cholesterol Particles Formation.
  The American journal of cardiology 2016 Madasamy S, Shivasubramani U, Villanueva J, Bigos M, Amento EP, Wu AH
• High-sensitivity cardiac troponin testing for primary care: analytical assay considerations required before widespread implementation.
  Annals of translational medicine 2016 Wu AH
• Laboratory Medicine in the Clinical Decision Support for Treatment of Hypercholesterolemia: Pharmacogenetics of Statins.
  Clinics in laboratory medicine 2016 Ruaño G, Seip R, Windemuth A, Wu AH, Thompson PD
• Counterfeit Norco Poisoning Outbreak - San Francisco Bay Area, California, March 25-April 5, 2016.
  MMWR. Morbidity and mortality weekly report 2016 Vo KT, van Wijk XM, Lynch KL, Wu AH, Smollin CG
• Development and Validation of a Novel LC-MS/MS Opioid Confirmation Assay: Evaluation of β-glucuronidase Enzymes and Sample Cleanup Methods.
  Journal of analytical toxicology 2016 Yang HS, Wu AH, Lynch KL
• Prognostic Value of Serial Changes in High-Sensitivity Cardiac Troponin I and T over 3 Months Using Reference Change Values in Hemodialysis Patients.
  Clinical chemistry 2016 Sandoval Y, Herzog CA, Love SA, Cao J, Hu Y, Wu AH, Gilbertson D, Brunelli SM, Young A, Ler R, Apple FS
• The standards for reporting diagnostic accuracy studies 2015 update: is there a missing link to the triumvirate?
  Annals of translational medicine 2016 Wu AH, Christenson RH
• Development and validation of an LC-MS/MS sulfonylurea assay for hypoglycemia cases in the emergency department.
  Clinica chimica acta; international journal of clinical chemistry 2016 Yang HS, Wu AH, Johnson-Davis KL, Lynch KL
• High-Resolution Mass Spectrometry for Untargeted Drug Screening.
  Methods in molecular biology (Clifton, N.J.) 2016 Wu AH, Colby J
• Diversity in Clinical and Biomedical Research: A Promise Yet to Be Fulfilled.
  PLoS medicine 2015 Oh SS, Galanter J, Thakur N, Pino-Yanes M, Barcelo NE, White MJ, de Bruin DM, Greenblatt RM, Bibbins-Domingo K, Wu AH, Borrell LN, Gunter C, Powe NR, Burchard EG
• SLE-key(®) rule-out serologic test for excluding the diagnosis of systemic lupus erythematosus: Developing the ImmunArray iCHIP(®).
  Journal of immunological methods 2015 Putterman C, Wu A, Reiner-Benaim A, Batty DS, Sanz I, Oates J, Jakobi K, Petri M, Safer P, Gerwien R, Sorek R, Blumenstein Y, Cohen IR
• Comparison of Information-Dependent Acquisition on a Tandem Quadrupole TOF vs a Triple Quadrupole Linear Ion Trap Mass Spectrometer for Broad-Spectrum Drug Screening.
  Clinical chemistry 2015 Thoren KL, Colby JM, Shugarts SB, Wu AH, Lynch KL
• Circulating Brain-Derived Neurotrophic Factor Has Diagnostic and Prognostic Value in Traumatic Brain Injury.
  Journal of neurotrauma 2015 Korley FK, Diaz-Arrastia R, Wu AH, Yue JK, Manley GT, Sair HI, Van Eyk J, Everett AD, TRACK-TBI investigators, Okonkwo DO, Valadka AB, Gordon WA, Maas AI, Mukherjee P, Yuh EL, Lingsma HF, Puccio AM, …
• Novel Biomarkers of Cardiac Stress, Cardiovascular Dysfunction, and Outcomes in HIV-Infected Individuals.
  JACC. Heart failure 2015 Secemsky EA, Scherzer R, Nitta E, Wu AH, Lange DC, Deeks SG, Martin JN, Snider J, Ganz P, Hsue PY
• Serial sampling of copeptin levels improves diagnosis and risk stratification in patients presenting with chest pain: results from the CHOPIN trial.
  Emergency medicine journal : EMJ 2015 Marston NA, Shah KS, Mueller C, Neath SX, Christenson RH, McCord J, Nowak RM, Daniels LB, Hollander JE, Apple F, Nagurney J, Schreiber D, deFilippi C, Diercks D, Limkakeng A, Anand IS, Wu AH, Jaffe AS…
• The Hawaii clopidogrel lawsuit: the possible effect on clinical laboratory testing.
  Personalized medicine 2015 Wu AH, White MJ, Oh S, Burchard E
• Midregional proadrenomedullin predicts mortality and major adverse cardiac events in patients presenting with chest pain: results from the CHOPIN trial.
  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2015 Shah KS, Marston NA, Mueller C, Neath SX, Christenson RH, McCord J, Nowak RM, Vilke GM, Daniels LB, Hollander JE, Apple FS, Cannon CM, Nagurney J, Schreiber D, deFilippi C, Hogan CJ, Diercks DB, …
• Prolonged neuropsychiatric effects following management of chloroquine intoxication with psychotropic polypharmacy.
  Clinical case reports 2015 Maxwell NM, Nevin RL, Stahl S, Block J, Shugarts S, Wu AH, Dominy S, Solano-Blanco MA, Kappelman-Culver S, Lee-Messer C, Maldonado J, Maxwell AJ
• Release of cardiac troponin using a high sensitivity assay after exercise: Type 2 acute myocardial infarction?
  Clinica chimica acta; international journal of clinical chemistry 2015 Aw TC, van Wijk XM, Wu AH, Jaffe AS
• Analysis of codeine positivity in urine of pain management patients.
  Journal of analytical toxicology 2015 Colby JM, Wu AH, Lynch KL
• Pharmacogenomic testing and response to warfarin.
  Lancet (London, England) 2015 Wu AH
• The birth and potential death of IL28B genotyping for hepatitis C therapy.
  Personalized medicine 2015 Wu AH, Khalili M
• The Open Physiology workflow: modeling processes over physiology circuitboards of interoperable tissue units.
  Frontiers in physiology 2015 de Bono B, Safaei S, Grenon P, Nickerson DP, Alexander S, Helvensteijn M, Kok JN, Kokash N, Wu A, Yu T, Hunter P, Baldock RA
• Analytical validation of novel cardiac biomarkers used in clinical trials.
  American heart journal 2015 Wu AH
• Investigation of postmortem absorption and redistribution after the application of a fentanyl patch.
  Journal of forensic sciences 2015 Wu AH, Hamilton R, Middleberg R, Kacinko S, Kearney T
• Predicting mortality after elective open-heart surgery using midregional-proadrenomedullin: is it time to scalp Acute Physiology and Chronic Health Evaluation IV?
  Critical care medicine 2015 Wu AH, Hale K
• Plaque array method and proteomics-based identification of biomarkers from Alzheimer's disease serum.
  Clinica chimica acta; international journal of clinical chemistry 2014 Madasamy S, Chaudhuri V, Kong R, Alderete B, Adams CM, Knaak TD, Ruan W, Wu AH, Bigos M, Amento EP
• ICMA: an integrated cardiac modeling and analysis platform.
  Bioinformatics (Oxford, England) 2014 Hussan JR, Hunter PJ, Gladding PA, Greenberg N, Christie R, Wu A, Sorby H, Thomas JD
• A new ultra-high sensitivity troponin I assay for chest pain patients with no evidence of troponin I using a conventional assay.
  Clinical biochemistry 2014 Wu AH, van Wijk XM
• Comparison of conventional and high-sensitivity troponin in patients with chest pain: a collaborative meta-analysis.
  American heart journal 2014 Lipinski MJ, Baker NC, Escárcega RO, Torguson R, Chen F, Aldous SJ, Christ M, Collinson PO, Goodacre SW, Mair J, Inoue K, Lotze U, Sebbane M, Cristol JP, Freund Y, Chenevier-Gobeaux C, Meune C, Eggers…
• Folate testing: time to retire your VCR.
  JAMA internal medicine 2014 Wu AH
• Absolute and relative changes (delta) in troponin I for early diagnosis of myocardial infarction: Results of a prospective multicenter trial.
  Clinical biochemistry 2014 Storrow AB, Nowak RM, Diercks DB, Singer AJ, Wu AH, Kulstad E, LoVecchio F, Fromm C, Headden G, Potis T, Hogan CJ, Schrock JW, Zelinski DP, Greenberg MR, Christenson RH, Ritchie JC, Chamberlin JS, …
• Cross-reactivity of acetylfentanyl and risperidone with a fentanyl immunoassay.
  Journal of analytical toxicology 2014 Wang BT, Colby JM, Wu AH, Lynch KL
• Diagnostic performance of cardiac Troponin I for early rule-in and rule-out of acute myocardial infarction: Results of a prospective multicenter trial.
  Clinical biochemistry 2014 Storrow AB, Christenson RH, Nowak RM, Diercks DB, Singer AJ, Wu AH, Kulstad E, LoVecchio F, Fromm C, Headden G, Potis T, Hogan CJ, Schrock JW, Zelinski DP, Greenberg MR, Ritchie JC, Chamberlin JS, …
• Biological variation of the osmolality and the osmolal gap.
  Clinical biochemistry 2014 Wu AH, Yang HS, Thoren K
• Improving the 510(k) FDA process for cardiac troponin assays: in search of common ground.
  Clinical chemistry 2014 Apple FS, Hollander J, Wu AH, Jaffe AS
• B-type natriuretic peptides for the prediction of cardiovascular events in patients with stable coronary heart disease: the Heart and Soul Study.
  Journal of the American Heart Association 2014 Mishra RK, Beatty AL, Jaganath R, Regan M, Wu AH, Whooley MA
• Biological variation of immunoglobulin heavy chain-light chain pairs in serum.
  Clinica chimica acta; international journal of clinical chemistry 2014 Finlay JA, Wu AH
• The pharmacogenomics of warfarin from the COAG and EU-PACT: where do we go from here?
  Personalized medicine 2014 Wu AH, Superko HR
• Biomarkers for cholesterol absorption and synthesis in hyperlipidemic patients: role for therapeutic selection.
  Clinics in laboratory medicine 2014 Wu AH
• Biological variation of β-sitosterol, campesterol, and lathosterol as cholesterol absorption and synthesis biomarkers.
  Clinica chimica acta; international journal of clinical chemistry 2014 Wu AH, Ruan W, Todd J, Lynch KL
• The current and future landscape of urinary thromboxane testing to evaluate atherothrombotic risk.
  Reviews in cardiovascular medicine 2014 Neath SX, Jefferies JL, Berger JS, Wu AH, McConnell JP, Boone JL, McCullough PA, Jesse RL, Maisel AS
• Biological and analytical variation of clinical biomarker testing: implications for biomarker-guided therapy.
  Current heart failure reports 2013 Wu AH
• Interpreting laboratory results in transgender patients on hormone therapy.
  The American journal of medicine 2013 Roberts TK, Kraft CS, French D, Ji W, Wu AH, Tangpricha V, Fantz CR
• Lack of impairment due to confirmed codeine use prior to a motor vehicle accident: role of pharmacogenomics.
  Journal of forensic and legal medicine 2013 Wu AH, Kearney T
• Personalized medicine in breast cancer: tamoxifen, endoxifen, and CYP2D6 in clinical practice.
  Breast cancer research and treatment 2013 Ruddy KJ, Desantis SD, Gelman RS, Wu AH, Punglia RS, Mayer EL, Tolaney SM, Winer EP, Partridge AH, Burstein HJ
• Genotype and phenotype concordance for pharmacogenetic tests through proficiency survey testing.
  Archives of pathology & laboratory medicine 2013 Wu AH
• Prolonged ventilatory failure and flaccid quadriparesis after ingestion of poison hemlock.
  Muscle & nerve 2013 Lung DD, Scott BJ, Wu AH, Gerona RR
• C3435T polymorphism of MDR1 gene with warfarin resistance.
  Clinica chimica acta; international journal of clinical chemistry 2013 Kim Y, Smith A, Wu AH
• Cardiotoxicity in a citalopram and olanzapine overdose.
  The Journal of emergency medicine 2013 Lung DD, Wu AH, Gerona RR
• Multi-wavelength spectrophotometric analysis for detection of xanthochromia in cerebrospinal fluid and accuracy for the diagnosis of subarachnoid hemorrhage.
  Clinica chimica acta; international journal of clinical chemistry 2013 Smith A, Wu AH, Lynch KL, Ko N, Grenache DG
• Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study.
  Lancet (London, England) 2013 Perera MA, Cavallari LH, Limdi NA, Gamazon ER, Konkashbaev A, Daneshjou R, Pluzhnikov A, Crawford DC, Wang J, Liu N, Tatonetti N, Bourgeois S, Takahashi H, Bradford Y, Burkley BM, Desnick RJ, Halperin…
• Atrial fibrillation impairs the diagnostic performance of cardiac natriuretic peptides in dyspneic patients: results from the BACH Study (Biomarkers in ACute Heart Failure).
  JACC. Heart failure 2013 Richards M, Di Somma S, Mueller C, Nowak R, Peacock WF, Ponikowski P, Mockel M, Hogan C, Wu AH, Clopton P, Filippatos GS, Anand I, Ng L, Daniels LB, Neath SX, Shah K, Christenson R, Hartmann O, Anker …
• Copeptin helps in the early detection of patients with acute myocardial infarction: primary results of the CHOPIN trial (Copeptin Helps in the early detection Of Patients with acute myocardial INfarction).
  Journal of the American College of Cardiology 2013 Maisel A, Mueller C, Neath SX, Christenson RH, Morgenthaler NG, McCord J, Nowak RM, Vilke G, Daniels LB, Hollander JE, Apple FS, Cannon C, Nagurney JT, Schreiber D, deFilippi C, Hogan C, Diercks DB, …
• Analytical and assay issues for use of cardiac troponin testing for risk stratification in primary care.
  Clinical biochemistry 2013 Wu AHB, Christenson RH
• Growing pains with the use of high-sensitivity cardiac troponin assays.
  Journal of the American College of Cardiology 2013 Wu AHB, Bolger AF, Hollander JE
• Biological variation of galectin-3 and soluble ST2 for chronic heart failure: implication on interpretation of test results.
  American heart journal 2013 Wu AH, Wians F, Jaffe A
• Myeloperoxidase and C-reactive protein in patients with cocaine-associated chest pain.
  The American journal of emergency medicine 2013 O'Conor K, Chang AM, Wu AH, Hollander JE
• Prescription compliance or illicit designer drug abuse?
  Clinical chemistry 2012 Petrie MS, Lynch KL, Wu AH, Steinhardt AA, Horowitz GL
• Stability of active ingredients in long-expired prescription medications.
  Archives of internal medicine 2012 Cantrell L, Suchard JR, Wu A, Gerona RR
• Simultaneous detection of multiple designer drugs in serum, urine, and CSF in a patient with prolonged psychosis.
  Clinical toxicology (Philadelphia, Pa.) 2012 Thornton SL, Lo J, Clark RF, Wu AH, Gerona RR
• Implementation of liquid chromatography/mass spectrometry into the clinical laboratory.
  Clinica chimica acta; international journal of clinical chemistry 2012 Wu AH, French D
• Biomarkers Beyond the Natriuretic Peptides for Chronic Heart Failure: Galectin-3 and Soluble ST2.
  EJIFCC 2012 Wu AH
• Mid-regional pro-adrenomedullin improves disposition strategies for patients with acute dyspnoea: results from the BACH trial.
  Emergency medicine journal : EMJ 2012 Möckel M, Searle J, Hartmann O, Anker SD, Peacock WF, Wu AH, Maisel A, BACH Writing group, Slagman A, Vollert JO, Papassotiriou J, Anand I, Christenson R, Daniels LB, Filippatos GS, Hogan C, …
• Bath salts.
  Clinics in laboratory medicine 2012 Gerona RR, Wu AH
• Determination of tobacco smoke exposure by plasma cotinine levels in infants and children attending urban public hospital clinics.
  Archives of pediatrics & adolescent medicine 2012 Dempsey DA, Meyers MJ, Oh SS, Nguyen EA, Fuentes-Afflick E, Wu AH, Jacob P, Benowitz NL
• Role of liquid chromatography-high-resolution mass spectrometry (LC-HR/MS) in clinical toxicology.
  Clinical toxicology (Philadelphia, Pa.) 2012 Wu AH, Gerona R, Armenian P, French D, Petrie M, Lynch KL
• Short-term (90 min) diagnostic performance for acute non-ST segment elevation myocardial infarction and 30-day prognostic evaluation of a novel third-generation high sensitivity troponin I assay.
  Clinical biochemistry 2012 Schreiber DH, Agbo C, Wu AH
• Estimation of tamoxifen metabolite concentrations in the blood of breast cancer patients through CYP2D6 genotype activity score.
  Breast cancer research and treatment 2012 Wu AH, Lorizio W, Tchu S, Lynch K, Gerona R, Ji W, Ruan W, Ruddy KJ, Desantis SD, Burstein HJ, Ziv E
• Multiple MDMA (Ecstasy) overdoses at a rave event: a case series.
  Journal of intensive care medicine 2012 Armenian P, Mamantov TM, Tsutaoka BT, Gerona RR, Silman EF, Wu AH, Olson KR
• The effect of diabetes on the diagnostic and prognostic performance of mid-region pro-atrial natriuretic peptide and mid-region pro-adrenomedullin in patients with acute dyspnea.
  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2012 Wu AH, Tabas J, Stein J, Potocki M, Mueller C, McCord J, Richards M, Hartmann O, Nowak R, Peacock WF, Ponikowski P, Moeckel M, Hogan C, Filippatos GS, Di Somma S, Anand I, Ng L, Neath SX, Christenson …
• An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports.
  American journal of hematology 2012 Rifai N, Annesley TM, Berg JP, Brugnara C, Delvin E, Lamb EJ, Ness PM, Plebani M, Wick MR, Wu A, Delanghe J
• An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports.
  Transfusion 2012 Rifai N, Annesley TM, Berg JP, Brugnara C, Delvin E, Lamb EJ, Ness PM, Plebani M, Wick MR, Wu A
• Long-term biological variation in cardiac troponin I.
  Clinical biochemistry 2012 Wu AH, Akhigbe P, Wians F
• An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports.
  Clinical chemistry and laboratory medicine 2012 Rifai N, Annesley TM, Berg JP, Brugnara C, Delvin E, Lamb EJ, Ness PM, Plebani M, Wick MR, Wu A, Delanghe J
• Accuracy of the initial diagnosis among patients with an acutely altered mental status.
  Emergency medicine journal : EMJ 2012 Sporer KA, Solares M, Durant EJ, Wang W, Wu AH, Rodriguez RM
• Multiple biomarkers for risk prediction in chronic heart failure.
  Circulation. Heart failure 2012 Ky B, French B, Levy WC, Sweitzer NK, Fang JC, Wu AH, Goldberg LR, Jessup M, Cappola TP
• An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports.
  Scandinavian journal of clinical and laboratory investigation 2012 Rifai N, Annesley TM, Berg JP, Brugnara C, Delvin E, Lamb EJ, Ness PM, Plebani M, Wick MR, Wu A, Delanghe J
• Use of procalcitonin for the diagnosis of pneumonia in patients presenting with a chief complaint of dyspnoea: results from the BACH (Biomarkers in Acute Heart Failure) trial.
  European journal of heart failure 2012 Maisel A, Neath SX, Landsberg J, Mueller C, Nowak RM, Peacock WF, Ponikowski P, Möckel M, Hogan C, Wu AH, Richards M, Clopton P, Filippatos GS, Di Somma S, Anand I, Ng LL, Daniels LB, Christenson RH, …
• A mixed (long- and medium-chain) triglyceride lipid emulsion extracts local anesthetic from human serum in vitro more effectively than a long-chain emulsion.
  Anesthesiology 2012 Ruan W, French D, Wong A, Drasner K, Wu AH
• An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports.
  Clinical chemistry 2012 Rifai N, Annesley TM, Berg JP, Brugnara C, Delvin E, Lamb EJ, Ness PM, Plebani M, Wick MR, Wu A, Delanghe J
• An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports.
  Clinical biochemistry 2012 Rifai N, Annesley TM, Berg JP, Brugnara C, Delvin E, Lamb EJ, Ness PM, Plebani M, Wick MR, Wu A
• An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports. Statement by the Consortium of Laboratory Medicine Journal Editors.
  Annals of clinical biochemistry 2012 Rifai N, Annesley TM, Berg JP, Brugnara C, Delvin E, Lamb EJ, Ness PM, Plebani M, Wick MR, Wu A, Delanghe J
• An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports.
  Clinica chimica acta; international journal of clinical chemistry 2012 Rifai N, Annesley TM, Berg JP, Brugnara C, Delvin E, Lamb EJ, Ness PM, Plebani M, Wick MR, Wu A, Delanghe J
• Therapeutic drug monitoring of tamoxifen using LC-MS/MS.
  Methods in molecular biology (Clifton, N.J.) 2012 Tchu SM, Lynch KL, Wu AH
• Clinical and biomarker predictors of side effects from tamoxifen.
  Breast cancer research and treatment 2011 Lorizio W, Wu AH, Beattie MS, Rugo H, Tchu S, Kerlikowske K, Ziv E
• Influence of age, race, sex, and body mass index on interpretation of midregional pro atrial natriuretic peptide for the diagnosis of acute heart failure: results from the BACH multinational study.
  European journal of heart failure 2011 Daniels LB, Clopton P, Potocki M, Mueller C, McCord J, Richards M, Hartmann O, Anand IS, Wu AH, Nowak R, Peacock WF, Ponikowski P, Mockel M, Hogan C, Filippatos GS, Di Somma S, Ng L, Neath SX, …
• Hydrophilic interaction LC-MS/MS analysis of opioids in urine: significance of glucuronide metabolites.
  Bioanalysis 2011 French D, Wu A, Lynch K
• Results of novel cardiac biomarkers in Tako-tsubo cardiomyopathy.
  International journal of cardiology 2011 Wu AH, Tabas JA, Vollert JO, Lauterbach T, Mockel M
• Troponin release--reversible or irreversible injury? Should we care?
  Clinical chemistry 2011 Jaffe AS, Wu AH
• Partition constant and volume of distribution as predictors of clinical efficacy of lipid rescue for toxicological emergencies.
  Clinical toxicology (Philadelphia, Pa.) 2011 French D, Smollin C, Ruan W, Wong A, Drasner K, Wu AH
• 5-oxoprolinemia causing elevated anion gap metabolic acidosis in the setting of acetaminophen use.
  The Journal of emergency medicine 2011 Armenian P, Gerona RR, Blanc PD, Wu AH, Mookherjee S
• Confirmed glyburide poisoning from ingestion of "street Valium".
  The Journal of emergency medicine 2011 Lung DD, Gerona RR, Wu AH, Smollin CG
• Pharmacogenetic testing affects choice of therapy among women considering tamoxifen treatment.
  Genome medicine 2011 Lorizio W, Rugo H, Beattie MS, Tchu S, Melese T, Melisko M, Wu AH, Lawrence HJ, Nikoloff M, Ziv E
• How well are we training the next generation of clinical pathologists and clinical laboratory directors? A global perspective.
  Clinical chemistry 2011 Scott MG, Smith BR, Wu AH, Young IS, Plebani M, Chiu RW
• False-positive urine phencyclidine immunoassay screen result caused by interference by tramadol and its metabolites.
  Annals of emergency medicine 2011 Ly BT, Thornton SL, Buono C, Stone JA, Wu AH
• Short-term mortality risk in emergency department acute heart failure.
  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2011 Peacock WF, Nowak R, Christenson R, DiSomma S, Neath SX, Hartmann O, Mueller C, Ponikowski P, Möckel M, Hogan C, Wu AH, Richards M, Filippatos GS, Anand I, Ng LL, Daniels LB, Morgenthaler N, Anker SD,…
• Midregion prohormone adrenomedullin and prognosis in patients presenting with acute dyspnea: results from the BACH (Biomarkers in Acute Heart Failure) trial.
  Journal of the American College of Cardiology 2011 Maisel A, Mueller C, Nowak RM, Peacock WF, Ponikowski P, Mockel M, Hogan C, Wu AH, Richards M, Clopton P, Filippatos GS, Di Somma S, Anand I, Ng LL, Daniels LB, Neath SX, Christenson R, Potocki M, …
• Elevated BNP is associated with vasospasm-independent cerebral infarction following aneurysmal subarachnoid hemorrhage.
  Neurocritical care 2011 Taub PR, Fields JD, Wu AH, Miss JC, Lawton MT, Smith WS, Young WL, Zaroff JG, Ko NU
• Drug metabolizing enzyme activities versus genetic variances for drug of clinical pharmacogenomic relevance.
  Clinical proteomics 2011 Wu AH
• Mechanisms of statin-induced myalgia assessed by physiogenomic associations.
  Atherosclerosis 2011 Ruaño G, Windemuth A, Wu AH, Kane JP, Malloy MJ, Pullinger CR, Kocherla M, Bogaard K, Gordon BR, Holford TR, Gupta A, Seip RL, Thompson PD
• Increased 90-day mortality in patients with acute heart failure with elevated copeptin: secondary results from the Biomarkers in Acute Heart Failure (BACH) study.
  Circulation. Heart failure 2011 Maisel A, Xue Y, Shah K, Mueller C, Nowak R, Peacock WF, Ponikowski P, Mockel M, Hogan C, Wu AH, Richards M, Clopton P, Filippatos GS, Di Somma S, Anand IS, Ng L, Daniels LB, Neath SX, Christenson R, …
• Clinical trials for pharmacogenomics testing for warfarin dosing: relevance to general community practices.
  Genetics in medicine : official journal of the American College of Medical Genetics 2011 Sidiropoulos N, Wu AH
• KRAS mutation detection in colorectal cancer by a commercially available gene chip array compares well with Sanger sequencing.
  Clinica chimica acta; international journal of clinical chemistry 2011 French D, Smith A, Powers MP, Wu AH
• Circulating macrocomplexes: old wine in new bottles?
  Clinical chemistry and laboratory medicine 2011 Plebani M, Wu AH
• Biological variation and reference change value of high-sensitivity troponin T in healthy individuals during short and intermediate follow-up periods.
  Clinical chemistry 2011 Frankenstein L, Wu AH, Hallermayer K, Wians FH, Giannitsis E, Katus HA
• Gene expression profiling from formalin-fixed, paraffin-embedded tissue for tumor diagnosis.
  Clinica chimica acta; international journal of clinical chemistry 2011 Grenert JP, Smith A, Ruan W, Pillai R, Wu AH
• Serum verapamil concentrations before and after Intralipid® therapy during treatment of an overdose.
  Clinical toxicology (Philadelphia, Pa.) 2011 French D, Armenian P, Ruan W, Wong A, Drasner K, Olson KR, Wu AH
• Full-disclosure in industry-sponsored laboratory medicine research studies: Statement by the Consortium of Laboratory Medicine Journal Editors.
  American journal of hematology 2011 Rifai N, Plebani M, Wu A, Brugnara C, Delvin E, Lamb EJ, Ness PM, Wick MR, Berg JP
• Failure of pharmacogenetic-based dosing algorithms to identify older patients requiring low daily doses of warfarin.
  Journal of the American Medical Directors Association 2011 Schwartz JB, Kane L, Moore K, Wu AH
• Placental growth factor and B-type natriuretic peptide as independent predictors of risk from a multibiomarker panel in suspected acute coronary syndrome (Acute Risk and Related Outcomes Assessed With Cardiac Biomarkers [ARROW]) study.
  The American journal of cardiology 2011 Glaser R, Peacock WF, Wu AH, Muller R, Möckel M, Apple FS
• Full disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors.
  Annals of clinical biochemistry 2011 Rifai N, Plebani M, Wu A, Brugnara C, Delvin E, Lamb EJ, Ness PM, Wick MR, Berg JP
• Full disclosure in industry-sponsored laboratory medicine research studies: Statement by the Consortium of Laboratory Medicine Journal Editors.
  Clinical biochemistry 2010 Rifai N, Plebani M, Wu AH, Brugnara C, Delvin E, Lamb EJ, Ness PM, Wick MR, Berg JP
• Full disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors.
  Transfusion 2010 Rifai N, Plebani M, Wu A, Brugnara C, Delvin E, Lamb EJ, Ness PM, Wick MR, Berg JP
• High-sensitivity ST2 for prediction of adverse outcomes in chronic heart failure.
  Circulation. Heart failure 2010 Ky B, French B, McCloskey K, Rame JE, McIntosh E, Shahi P, Dries DL, Tang WH, Wu AH, Fang JC, Boxer R, Sweitzer NK, Levy WC, Goldberg LR, Jessup M, Cappola TP
• Full-disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors.
  Scandinavian journal of clinical and laboratory investigation 2010 Rifai N, Plebani M, Wu A, Brugnara C, Delvin E, Lamb EJ, Ness PM, Wick MR, Berg JP
• Full disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors.
  Clinical chemistry 2010 Rifai N, Plebani M, Wu A, Brugnara C, Delvin E, Lamb EJ, Ness PM, Wick MR, Berg JP
• Full-disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors.
  Clinical chemistry and laboratory medicine 2010 Rifai N, Plebani M, Wu A, Brugnara C, Delvin E, Lamb EJ, Ness PM, Wick MR, Berg JP
• A case of a rapid drop in lactate.
  The American journal of emergency medicine 2010 French D, Branch J, Wu AH, Winston L, Fiebig EW
• Full-disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors.
  Clinica chimica acta; international journal of clinical chemistry 2010 Rifai N, Plebani M, Wu AH, Delanghe J, Brugnara C, Delvin E, Lamb EJ, Ness PM, Wick MR, Berg JP
• Vitamin D status of county hospital patients assessed by the DiaSorin LIAISON® 25-hydroxyvitamin D assay.
  Clinica chimica acta; international journal of clinical chemistry 2010 French D, Gorgi AW, Ihenetu KU, Weeks MA, Lynch KL, Wu AH
• Characterization of 107 genomic DNA reference materials for CYP2D6, CYP2C19, CYP2C9, VKORC1, and UGT1A1: a GeT-RM and Association for Molecular Pathology collaborative project.
  The Journal of molecular diagnostics : JMD 2010 Pratt VM, Zehnbauer B, Wilson JA, Baak R, Babic N, Bettinotti M, Buller A, Butz K, Campbell M, Civalier C, El-Badry A, Farkas DH, Lyon E, Mandal S, McKinney J, Muralidharan K, Noll L, Sander T, …
• Using genetic and clinical factors to predict tacrolimus dose in renal transplant recipients.
  Pharmacogenomics 2010 Wang P, Mao Y, Razo J, Zhou X, Wong ST, Patel S, Elliott E, Shea E, Wu AH, Gaber AO
• Antiquated tests within the clinical pathology laboratory.
  The American journal of managed care 2010 Wu AH, Lewandrowski K, Gronowski AM, Grenache DG, Sokoll LJ, Magnani B
• Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?
  Pharmacogenomics 2010 Ruaño G, Thompson PD, Kane JP, Pullinger CR, Windemuth A, Seip RL, Kocherla M, Holford TR, Wu AH
• Performance evaluation of three liquid chromatography mass spectrometry methods for broad spectrum drug screening.
  Clinica chimica acta; international journal of clinical chemistry 2010 Lynch KL, Breaud AR, Vandenberghe H, Wu AH, Clarke W
• From personalized medicine to personalized justice: the promises of translational pharmacogenomics in the justice system.
  Pharmacogenomics 2010 Wong SH, Happy C, Blinka D, Gock S, Jentzen JM, Donald Hon J, Coleman H, Jortani SA, Lucire Y, Morris-Kukoski CL, Neuman MG, Orsulak PJ, Sander T, Wagner MA, Wynn JR, Wu AH, Yeo KT
• Mid-region pro-hormone markers for diagnosis and prognosis in acute dyspnea: results from the BACH (Biomarkers in Acute Heart Failure) trial.
  Journal of the American College of Cardiology 2010 Maisel A, Mueller C, Nowak R, Peacock WF, Landsberg JW, Ponikowski P, Mockel M, Hogan C, Wu AH, Richards M, Clopton P, Filippatos GS, Di Somma S, Anand I, Ng L, Daniels LB, Neath SX, Christenson R, …
• Interpretation and utility of drug of abuse immunoassays: lessons from laboratory drug testing surveys.
  Archives of pathology & laboratory medicine 2010 Melanson SE, Baskin L, Magnani B, Kwong TC, Dizon A, Wu AH
• Gene expression profiles help identify the tissue of origin for metastatic brain cancers.
  Diagnostic pathology 2010 Wu AH, Drees JC, Wang H, VandenBerg SR, Lal A, Henner WD, Pillai R
• High-sensitivity cardiac troponin assays: what analytical and clinical issues need to be addressed before introduction into clinical practice? Interview by Fred S. Apple.
  Clinical chemistry 2010 Wu A, Collinson P, Jaffe A, Morrow D
• Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups.
  Blood 2010 Limdi NA, Wadelius M, Cavallari L, Eriksson N, Crawford DC, Lee MT, Chen CH, Motsinger-Reif A, Sagreiya H, Liu N, Wu AH, Gage BF, Jorgensen A, Pirmohamed M, Shin JG, Suarez-Kurtz G, Kimmel SE, Johnson…
• Lack of gamma-hydroxybutyrate prevalence among an urban emergency department population.
  Journal of analytical toxicology 2010 Ureda N, Ruan W, French D, Wu AH
• Standardization of assays for clinically important enzymes that have high biologic variation: what is all the fuss about?
  Clinical chemistry and laboratory medicine 2010 Wu AH
• Multi-center determination of galectin-3 assay performance characteristics: Anatomy of a novel assay for use in heart failure.
  Clinical biochemistry 2010 Christenson RH, Duh SH, Wu AH, Smith A, Abel G, deFilippi CR, Wang S, Adourian A, Adiletto C, Gardiner P
• Simultaneous assessment of unprocessed ProBNP1-108 in addition to processed BNP32 improves identification of high-risk ambulatory patients with heart failure.
  Circulation. Heart failure 2010 Dries DL, Ky B, Wu AH, Rame JE, Putt ME, Cappola TP
• Cardiac troponin may be released by ischemia alone, without necrosis.
  Clinica chimica acta; international journal of clinical chemistry 2009 Hickman PE, Potter JM, Aroney C, Koerbin G, Southcott E, Wu AH, Roberts MS
• Pharmacogenomic testing for warfarin dosing: we are ready now.
  Expert review of cardiovascular therapy 2009 Wu AH
• Morbidity involving the hallucinogenic designer amines MDA and 2C-I.
  Journal of forensic sciences 2009 Drees JC, Stone JA, Wu AH
• Impact of systemic hypertension on the diagnostic performance of B-type natriuretic peptide in patients with acute dyspnea.
  The American journal of cardiology 2009 Pahle AS, Sørli D, Omland T, Knudsen CW, Westheim A, Wu AH, Steg PG, McCord J, Nowak RM, Hollander JE, Storrow AB, Abraham WT, McCullough PA, Maisel A
• Prevalence and prognostic significance of incidental cardiac troponin T elevation in ambulatory patients with stable coronary artery disease: data from the Heart and Soul study.
  American heart journal 2009 Hsieh BP, Rogers AM, Na B, Wu AH, Schiller NB, Whooley MA
• Dysfunctional corin i555(p568) allele is associated with impaired brain natriuretic peptide processing and adverse outcomes in blacks with systolic heart failure: results from the Genetic Risk Assessment in Heart Failure substudy.
  Circulation. Heart failure 2009 Rame JE, Tam SW, McNamara D, Worcel M, Sabolinski ML, Wu AH, Dries DL
• Short- and long-term cardiac troponin I analyte stability in plasma and serum from healthy volunteers by use of an ultrasensitive, single-molecule counting assay.
  Clinical chemistry 2009 Wu AH, Shea E, Lu QT, Minyard J, Bui K, Hsu JC, Agee SJ, Todd J
• Prevalence of smoking assessed biochemically in an urban public hospital: a rationale for routine cotinine screening.
  American journal of epidemiology 2009 Benowitz NL, Schultz KE, Haller CA, Wu AH, Dains KM, Jacob P
• Analytical assay characterization for 1-108 pro-B-type natriuretic peptide on the BioPlex 2200 analyzer.
  Clinica chimica acta; international journal of clinical chemistry 2009 Wu AH, Smith A, Rame E, Wians F, Minard F, Giuliani I, Larue C
• N-terminal pro-B-type natriuretic peptide and inducible ischemia in the Heart and Soul Study.
  Clinical cardiology 2009 Singh HS, Bibbins-Domingo K, Ali S, Wu AH, Schiller NB, Whooley MA
• Implementation of pharmacogenomics into the clinical practice of therapeutics: issues for the clinician and the laboratorian.
  Personalized medicine 2009 Wu AH, Babic N, Yeo KJ
• Mass spectrometry in the clinical laboratory: how have we done, and where do we need to be?
  Clinical chemistry 2009 Annesley T, Majzoub J, Hsing A, Wu A, Rockwood A, Mason D
• Gender-specific decision limits for cardiac troponin for risk stratification?
  Anesthesia and analgesia 2009 Wu AH
• Etiologies of troponin elevation in critically ill patients with gastrointestinal bleeding.
  Critical care medicine 2009 Wu AH
• Specificity of a high-sensitivity cardiac troponin I assay using single-molecule-counting technology.
  Clinical chemistry 2009 Wu AH, Agee SJ, Lu QA, Todd J, Jaffe AS
• Interpretation of high sensitivity cardiac troponin I results: reference to biological variability in patients who present to the emergency room with chest pain: case report series.
  Clinica chimica acta; international journal of clinical chemistry 2008 Wu AH
• Clinical utility of an LC-MS/MS seizure panel for common drugs involved in drug-induced seizures.
  Clinical chemistry 2008 Drees JC, Stone JA, Olson KR, Meier KH, Gelb AM, Wu AH
• Novel biomarkers of cardiovascular disease: myeloperoxidase for acute and/or chronic heart failure?
  Clinical chemistry 2008 Wu AH
• Short- and long-term biological variation in cardiac troponin I measured with a high-sensitivity assay: implications for clinical practice.
  Clinical chemistry 2008 Wu AH, Lu QA, Todd J, Moecks J, Wians F
• Interpretation of creatine kinase and aldolase for statin-induced myopathy: Reliance on serial testing based on biological variation.
  Clinica chimica acta; international journal of clinical chemistry 2008 Wu AH, Smith A, Wians F
• Integrated Biomarkers in Cardiovascular Disease - Third International Symposium.
  IDrugs : the investigational drugs journal 2008 Wu A
• A hydrophilic-interaction chromatography tandem mass spectrometry method for quantitation of serum s-adenosylmethionine in patients infected with human immunodeficiency virus.
  Clinica chimica acta; international journal of clinical chemistry 2008 Wang P, Huang L, Davis JL, Swartzman A, Roth B, Stone J, Wu AH
• Cardiac troponin and outcome in acute heart failure.
  The New England journal of medicine 2008 Peacock WF, De Marco T, Fonarow GC, Diercks D, Wynne J, Apple FS, Wu AH, ADHERE Investigators
• High carrier prevalence of combinatorial CYP2C9 and VKORC1 genotypes affecting warfarin dosing.
  Personalized medicine 2008 Ruaño G, Thompson PD, Villagra D, Bower B, Kocherla M, Yazdanpanah G, Seip RL, Windemuth A, White CM, Duconge J, Holford TR, Wu AH
• Diagnostic performance of a new automated heterophile antibody test in adults and children.
  Diagnostic microbiology and infectious disease 2008 Klutts JS, Wu AH, Smith A, Yen-Lieberman B, Gronowski AM
• Cross-reactivity of BNP, NT-proBNP, and proBNP in commercial BNP and NT-proBNP assays: preliminary observations from the IFCC Committee for Standardization of Markers of Cardiac Damage.
  Clinical chemistry 2008 Luckenbill KN, Christenson RH, Jaffe AS, Mair J, Ordonez-Llanos J, Pagani F, Tate J, Wu AH, Ler R, Apple FS
• Dosing algorithm for warfarin using CYP2C9 and VKORC1 genotyping from a multi-ethnic population: comparison with other equations.
  Pharmacogenomics 2008 Wu AH, Wang P, Smith A, Haller C, Drake K, Linder M, Valdes R
• State-wide hospital clinical laboratory plan for measuring cholinesterase activity for individuals suspected of exposure to nerve agent chemical weapons.
  Clinical toxicology (Philadelphia, Pa.) 2008 Wu AH, Smith A, McComb R, Bowers GN, Makowski GS, McKay CA, Vena J, McDonagh J, Hopfer S, Sena SF, Malkus H, Forte E, Kelly K
• The clinical need for high-sensitivity cardiac troponin assays for acute coronary syndromes and the role for serial testing.
  American heart journal 2007 Wu AH, Jaffe AS
• National Academy of Clinical Biochemistry and IFCC Committee for Standardization of Markers of Cardiac Damage Laboratory Medicine Practice Guidelines: analytical issues for biomarkers of heart failure.
  Clinical biochemistry 2007 Apple FS, Wu AH, Jaffe AS, Panteghini M, Christenson RH, NACB Committee, IFCC C-SMCD
• National Academy of Clinical Biochemistry laboratory medicine practice guidelines: use of cardiac troponin and B-type natriuretic peptide or N-terminal proB-type natriuretic peptide for etiologies other than acute coronary syndromes and heart failure.
  Clinical chemistry 2007 NACB Writing Group, Wu AH, Jaffe AS, Apple FS, Jesse RL, Francis GL, Morrow DA, Newby LK, Ravkilde J, Tang WH, Christenson RH, NACB Committee, Cannon CP, Storrow AB
• Physiogenomic association of statin-related myalgia to serotonin receptors.
  Muscle & nerve 2007 Ruaño G, Thompson PD, Windemuth A, Seip RL, Dande A, Sorokin A, Kocherla M, Smith A, Holford TR, Wu AH
• Measurement of the interleukin family member ST2 in patients with acute dyspnea: results from the PRIDE (Pro-Brain Natriuretic Peptide Investigation of Dyspnea in the Emergency Department) study.
  Journal of the American College of Cardiology 2007 Januzzi JL, Peacock WF, Maisel AS, Chae CU, Jesse RL, Baggish AL, O'Donoghue M, Sakhuja R, Chen AA, van Kimmenade RR, Lewandrowski KB, Lloyd-Jones DM, Wu AH
• Multi-center validation of the Response Biomedical Corporation RAMP NT-proBNP assay with comparison to the Roche Diagnostics GmbH Elecsys proBNP assay.
  Clinica chimica acta; international journal of clinical chemistry 2007 Lee-Lewandrowski E, Januzzi JL, Green SM, Tannous B, Wu AH, Smith A, Wong A, Murakami MM, Kaczmarek J, Apple FS, Miller WL, Hartman K, Jaffe AS
• National Academy of Clinical Biochemistry Laboratory Medicine practice guidelines: Clinical utilization of cardiac biomarker testing in heart failure.
  Circulation 2007 Tang WH, Francis GS, Morrow DA, Newby LK, Cannon CP, Jesse RL, Storrow AB, Christenson RH, Apple FS, Ravkilde J, Wu AH, National Academy of Clinical Biochemistry Laboratory Medicine
• National Academy of Clinical Biochemistry and IFCC Committee for Standardization of Markers of Cardiac Damage Laboratory Medicine practice guidelines: Analytical issues for biomarkers of heart failure.
  Circulation 2007 Apple FS, Wu AH, Jaffe AS, Panteghini M, Christenson RH, Cannon CP, Francis G, Jesse RL, Morrow DA, Newby LK, Storrow AB, Tang WH, Pagani F, Tate J, Ordonez-Llanos J, Mair J, National Academy of …
• Association between anaemia and N-terminal pro-B-type natriuretic peptide (NT-proBNP): findings from the Heart and Soul Study.
  European journal of heart failure 2007 Desai AS, Bibbins-Domingo K, Shlipak MG, Wu AH, Ali S, Whooley MA
• Use of genetic and nongenetic factors in warfarin dosing algorithms.
  Pharmacogenomics 2007 Wu AH
• Early detection of acute coronary syndromes and risk stratification by multimarker analysis.
  Biomarkers in medicine 2007 Wu AH
• ST2 in emergency department chest pain patients with potential acute coronary syndromes.
  Annals of emergency medicine 2007 Brown AM, Wu AH, Clopton P, Robey JL, Hollander JE
• National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines: Clinical characteristics and utilization of biochemical markers in acute coronary syndromes.
  Circulation 2007 Morrow DA, Cannon CP, Jesse RL, Newby LK, Ravkilde J, Storrow AB, Wu AH, Christenson RH, National Academy of Clinical Biochemistry
• National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines: clinical characteristics and utilization of biochemical markers in acute coronary syndromes.
  Clinical chemistry 2007 Morrow DA, Cannon CP, Jesse RL, Newby LK, Ravkilde J, Storrow AB, Wu AH, Christenson RH, Apple FS, Francis G, Tang W, National Academy of Clinical Biochemistry
• National Academy of Clinical Biochemistry and IFCC Committee for Standardization of Markers of Cardiac Damage Laboratory Medicine Practice Guidelines: Analytical issues for biochemical markers of acute coronary syndromes.
  Circulation 2007 Apple FS, Jesse RL, Newby LK, Wu AH, Christenson RH, National Academy of Clinical Biochemistry, IFCC Committee for Standardization of Markers of Cardiac Damage
• National Academy of Clinical Biochemistry and IFCC Committee for Standardization of Markers of Cardiac Damage Laboratory Medicine Practice Guidelines: analytical issues for biochemical markers of acute coronary syndromes.
  Clinical chemistry 2007 Apple FS, Jesse RL, Newby LK, Wu AH, Christenson RH, Cannon CP, Francis G, Morrow DA, Ravkilde J, Storrow AB, Tang W, IFCC Comittee on Standardization of Markers of Cardiac Damege, Jaffe AS, Mair J, …
• Images in clinical medicine. Bright green serum.
  The New England journal of medicine 2007 Bailey H, Wu AH
• N-terminal pro-B-type natriuretic peptide as a diagnostic test for ventricular dysfunction in patients with coronary disease: data from the heart and soul study.
  Archives of internal medicine 2007 Corteville DC, Bibbins-Domingo K, Wu AH, Ali S, Schiller NB, Whooley MA
• Diminished need for folate measurements among indigent populations in the post folic acid supplementation era.
  Archives of pathology & laboratory medicine 2007 Joelson DW, Fiebig EW, Wu AH
• Alcohol dehydrogenase and catalase content in perinatal infant and adult livers: potential influence on neonatal alcohol metabolism.
  Toxicology letters 2007 Tran MN, Wu AH, Hill DW
• N-terminal fragment of the prohormone brain-type natriuretic peptide (NT-proBNP), cardiovascular events, and mortality in patients with stable coronary heart disease.
  JAMA 2007 Bibbins-Domingo K, Gupta R, Na B, Wu AH, Schiller NB, Whooley MA
• Transfusion-related acute lung injury and transfusion-associated circulatory overload: mutually exclusive or coexisting entities?
  Transfusion 2007 Fiebig EW, Wu AH, Krombach J, Tang J, Nguyen KA, Toy P
• Marathoner's heart?
  Circulation 2006 Thompson PD, Apple FS, Wu A
• Development and preliminary clinical validation of a high sensitivity assay for cardiac troponin using a capillary flow (single molecule) fluorescence detector.
  Clinical chemistry 2006 Wu AH, Fukushima N, Puskas R, Todd J, Goix P
• Serial testing of B-type natriuretic peptide and NTpro-BNP for monitoring therapy of heart failure: the role of biologic variation in the interpretation of results.
  American heart journal 2006 Wu AH
• Cardiac troponin: friend of the cardiac physician, foe to the cardiac patient?
  Circulation 2006 Wu AH
• Incomplete recovery of prescription opioids in urine using enzymatic hydrolysis of glucuronide metabolites.
  Journal of analytical toxicology 2006 Wang P, Stone JA, Chen KH, Gross SF, Haller CA, Wu AH
• Toward standardization of cardiac troponin I measurements part II: assessing commutability of candidate reference materials and harmonization of cardiac troponin I assays.
  Clinical chemistry 2006 Christenson RH, Duh SH, Apple FS, Bodor GS, Bunk DM, Panteghini M, Welch MJ, Wu AH, Kahn SE
• Plasma BNP/NT-proBNP assays: what do they target and what else might they recognize?
  Heart failure clinics 2006 Wu AH
• High carrier prevalence of deficient and null alleles of CYP2 genes in a major USA hospital: implications for  personalized drug safety.
  Personalized medicine 2006 Ruaño G, Makowski G, Windemuth A, Kocherla M, Weiss S, Goethe JW, Bower B, Wu AH, Thompson PD
• How obesity affects the cut-points for B-type natriuretic peptide in the diagnosis of acute heart failure. Results from the Breathing Not Properly Multinational Study.
  American heart journal 2006 Daniels LB, Clopton P, Bhalla V, Krishnaswamy P, Nowak RM, McCord J, Hollander JE, Duc P, Omland T, Storrow AB, Abraham WT, Wu AH, Steg PG, Westheim A, Knudsen CW, Perez A, Kazanegra R, Herrmann HC, …
• A selected history and future of immunoassay development and applications in clinical chemistry.
  Clinica chimica acta; international journal of clinical chemistry 2006 Wu AH
• Influence of imprecision on ROC curve analysis for cardiac markers.
  Clinical chemistry 2006 Kupchak P, Wu AH, Ghani F, Newby LK, Ohman EM, Christenson RH
• Further insight on amylase and lipase.
  MLO: medical laboratory observer 2006 Wu AH, Gross S
• Cardiovascular predictors of in-patient mortality after subarachnoid hemorrhage.
  Neurocritical care 2006 Yarlagadda S, Rajendran P, Miss JC, Banki NM, Kopelnik A, Wu AH, Ko N, Gelb AW, Lawton MT, Smith WS, Young WL, Zaroff JG
• Impact of the history of congestive heart failure on the utility of B-type natriuretic peptide in the emergency diagnosis of heart failure: results from the Breathing Not Properly Multinational Study.
  The American journal of medicine 2006 Strunk A, Bhalla V, Clopton P, Nowak RM, McCord J, Hollander JE, Duc P, Storrow AB, Abraham WT, Wu AH, Steg G, Perez A, Kazanegra R, Herrmann HC, Aumont MC, McCullough PA, Maisel A
• Physiogenomic analysis links serum creatine kinase activities during statin therapy to vascular smooth muscle homeostasis.
  Pharmacogenomics 2005 Ruaño G, Thompson PD, Windemuth A, Smith A, Kocherla M, Holford TR, Seip R, Wu AH
• Relationship of B-type natriuretic peptide and anemia in patients with and without heart failure: a substudy from the Breathing Not Properly (BNP) Multinational Study.
  American journal of hematology 2005 Wu AH, Omland T, Wold Knudsen C, McCord J, Nowak RM, Hollander JE, Duc P, Storrow AB, Abraham WT, Clopton P, Maisel AS, McCullough PA, Breathing Not Properly Multinational Study Investigations
• Validation of the 99th percentile cutoff independent of assay imprecision (CV) for cardiac troponin monitoring for ruling out myocardial infarction.
  Clinical chemistry 2005 Apple FS, Parvin CA, Buechler KF, Christenson RH, Wu AH, Jaffe AS
• B-type natriuretic peptide levels in patients in the emergency department with possible heart failure and previous stable angina pectoris and/or healed myocardial infarction.
  The American journal of cardiology 2005 McCord J, Nowak RM, Jacobsen G, Sallach JA, Wu AH, Perez A, Omland T, Knudsen CW, Westheim A, Duc P, Steg PG, Hollander JE, Herrmann HC, Storrow AB, Abraham WT, Lamba S, McCullough PA, Maisel A
• Impact of atrial fibrillation on the diagnostic performance of B-type natriuretic peptide concentration in dyspneic patients: an analysis from the breathing not properly multinational study.
  Journal of the American College of Cardiology 2005 Knudsen CW, Omland T, Clopton P, Westheim A, Wu AH, Duc P, McCord J, Nowak RM, Hollander JE, Storrow AB, Abraham WT, McCullough PA, Maisel A
• Predictors of elevated B-type natriuretic peptide concentrations in dyspneic patients without heart failure: an analysis from the breathing not properly multinational study.
  Annals of emergency medicine 2005 Knudsen CW, Clopton P, Westheim A, Klemsdal TO, Wu AH, Duc P, McCord J, Nowak RM, Hollander JE, Storrow AB, Abraham WT, McCullough PA, Maisel AS, Omland T
• Clinical significance of hepatic derangement in severe acute respiratory syndrome.
  World journal of gastroenterology 2005 Chan HL, Kwan AC, To KF, Lai ST, Chan PK, Leung WK, Lee N, Wu A, Sung JJ
• Future biomarkers for detection of ischemia and risk stratification in acute coronary syndrome.
  Clinical chemistry 2005 Apple FS, Wu AH, Mair J, Ravkilde J, Panteghini M, Tate J, Pagani F, Christenson RH, Mockel M, Danne O, Jaffe AS, Committee on Standardization of Markers of Cardiac Damage of the IFCC
• Quality specifications for B-type natriuretic peptide assays.
  Clinical chemistry 2005 Apple FS, Panteghini M, Ravkilde J, Mair J, Wu AH, Tate J, Pagani F, Christenson RH, Jaffe AS, Committee on Standardization of Markers of Cardiac Damage of the IFCC
• The use of plasma metanephrine to normetanephrine ratio to determine epinephrine poisoning.
  Clinica chimica acta; international journal of clinical chemistry 2005 Yaworsky DC, Wu AH, Hill DW
• Comparative sensitivities between different plasma B-type natriuretic peptide assays in patients with minimally symptomatic heart failure.
  Clinical cornerstone 2005 Tang WH, Philip K, Hazen SL, Stevenson CE, Pepoy M, Neale S, Francis GS, Van Lente F, Smith A, Wu AH
• Markers for early detection of cardiac diseases.
  Scandinavian journal of clinical and laboratory investigation. Supplementum 2005 Wu AH
• When the drug of choice is a drug of confusion: embalming fluid use in inner city Hartford, CT.
  Journal of ethnicity in substance abuse 2005 Singer M, Mirhej G, Shaw S, Saleheen H, Vivian J, Hastings E, Rohena L, Jennings D, Navarro J, Santelices C, Wu AH, Smith A, Perez A
• Effects of early corticosteroid treatment on plasma SARS-associated Coronavirus RNA concentrations in adult patients.
  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2004 Lee N, Allen Chan KC, Hui DS, Ng EK, Wu A, Chiu RW, Wong VW, Chan PK, Wong KT, Wong E, Cockram CS, Tam JS, Sung JJ, Lo YM
• Severe acute respiratory syndrome: thin-section computed tomography features, temporal changes, and clinicoradiologic correlation during the convalescent period.
  Journal of computer assisted tomography 2004 Wong KT, Antonio GE, Hui DS, Ho C, Chan PN, Ng WH, Shing KK, Wu A, Lee N, Yap F, Joynt GM, Sung JJ, Ahuja AT
• The effect of diabetes on B-type natriuretic peptide concentrations in patients with acute dyspnea: an analysis from the Breathing Not Properly Multinational Study.
  Diabetes care 2004 Wu AH, Omland T, Duc P, McCord J, Nowak RM, Hollander JE, Herrmann HC, Steg PG, Wold Knudsen C, Storrow AB, Abraham WT, Perez A, Kamin R, Clopton P, Maisel AS, McCullough PA, Breathing Not Properly …
• Severe acute respiratory syndrome: correlation between clinical outcome and radiologic features.
  Radiology 2004 Hui DS, Wong KT, Antonio GE, Lee N, Wu A, Wong V, Lau W, Wu JC, Tam LS, Yu LM, Joynt GM, Chung SS, Ahuja AT, Sung JJ
• Evaluation of a point-of-care assay for cardiac markers for patients suspected of acute myocardial infarction.
  Clinica chimica acta; international journal of clinical chemistry 2004 Wu AH, Smith A, Christenson RH, Murakami MM, Apple FS
• Quality specifications in thyroid diseases.
  Clinica chimica acta; international journal of clinical chemistry 2004 Wu AH
• Optimum blood collection intervals for B-type natriuretic peptide testing in patients with heart failure.
  The American journal of cardiology 2004 Wu AH, Smith A, Apple FS
• Diagnostic criteria during SARS outbreak in Hong Kong.
  Emerging infectious diseases 2004 Chan LY, Lee N, Chan PK, Wu A, Rainer TH, Li PK, Fung H, Sung JJ
• Impact of age, race, and sex on the ability of B-type natriuretic peptide to aid in the emergency diagnosis of heart failure: results from the Breathing Not Properly (BNP) multinational study.
  American heart journal 2004 Maisel AS, Clopton P, Krishnaswamy P, Nowak RM, McCord J, Hollander JE, Duc P, Omland T, Storrow AB, Abraham WT, Wu AH, Steg G, Westheim A, Knudsen CW, Perez A, Kazanegra R, Bhalla V, Herrmann HC, …
• Seroprevalence of antibody to severe acute respiratory syndrome (SARS)-associated coronavirus among health care workers in SARS and non-SARS medical wards.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2004 Ip M, Chan PK, Lee N, Wu A, Ng TK, Chan L, Ng A, Kwan HM, Tsang L, Chu I, Cheung JL, Sung JJ, Tam JS
• Laboratory diagnosis of SARS.
  Emerging infectious diseases 2004 Chan PK, To WK, Ng KC, Lam RK, Ng TK, Chan RC, Wu A, Yu WC, Lee N, Hui DS, Lai ST, Hon EK, Li CK, Sung JJ, Tam JS
• Reflex testing III: efficient use of laboratory markers for anemia.
  Clinica chimica acta; international journal of clinical chemistry 2004 Wu AH
• The spectrum of severe acute respiratory syndrome-associated coronavirus infection.
  Annals of internal medicine 2004 Rainer TH, Chan PK, Ip M, Lee N, Hui DS, Smit D, Wu A, Ahuja AT, Tam JS, Sung JJ, Cameron P
• Retrospective analysis of liver function derangement in severe acute respiratory syndrome.
  The American journal of medicine 2004 Chan HL, Leung WK, To KF, Chan PK, Lee N, Wu A, Tam JS, Sung JJ
• Biological variation of the natriuretic peptides and their role in monitoring patients with heart failure.
  European journal of heart failure 2004 Wu AH, Smith A
• Diagnostic value of B-Type natriuretic peptide and chest radiographic findings in patients with acute dyspnea.
  The American journal of medicine 2004 Knudsen CW, Omland T, Clopton P, Westheim A, Abraham WT, Storrow AB, McCord J, Nowak RM, Aumont MC, Duc P, Hollander JE, Wu AH, McCullough PA, Maisel AS
• Reduced readmission rate for alternating diagnoses of heart failure and pulmonary disease after implementation of B-type natriuretic peptide testing.
  European journal of heart failure 2004 Wu AH, Harrison A, Maisel AS
• Analytical and clinical evaluation of the Bayer ADVIA Centaur automated B-type natriuretic peptide assay in patients with heart failure: a multisite study.
  Clinical chemistry 2004 Wu AH, Packer M, Smith A, Bijou R, Fink D, Mair J, Wallentin L, Johnston N, Feldcamp CS, Haverstick DM, Ahnadi CE, Grant A, Despres N, Bluestein B, Ghani F
• Immunofluorescence assay for serologic diagnosis of SARS.
  Emerging infectious diseases 2004 Chan PK, Ng KC, Chan RC, Lam RK, Chow VC, Hui M, Wu A, Lee N, Yap FH, Cheng FW, Sung JJ, Tam JS
• Standardization of immunoassays for measurement of myoglobin in serum. Phase I: evaluation of candidate secondary reference materials.
  Clinica chimica acta; international journal of clinical chemistry 2004 Panteghini M, Linsinger T, Wu AH, Dati F, Apple FS, Christenson RH, Mair J, Schimmel H
• Evaluation of two-dimensional cytometric lamellar body counts on the ADVIA 120 hematology system for estimation of fetal lung maturation.
  Clinica chimica acta; international journal of clinical chemistry 2004 Chapman JF, Ashwood ER, Feld R, Wu AH
• The effect of class-specific protease inhibitors on the stabilization of B-type natriuretic peptide in human plasma.
  Clinica chimica acta; international journal of clinical chemistry 2004 Belenky A, Smith A, Zhang B, Lin S, Despres N, Wu AH, Bluestein BI
• The role of cardiac troponin in the recent redefinition of acute myocardial infarction.
  Clinical laboratory science : journal of the American Society for Medical Technology 2004 Wu AH
• Evaluation of imprecision for cardiac troponin assays at low-range concentrations.
  Clinical chemistry 2003 Panteghini M, Pagani F, Yeo KT, Apple FS, Christenson RH, Dati F, Mair J, Ravkilde J, Wu AH, Committee on Standardization of Markers of Cardiac Damage of the IFCC
• Multicenter evaluation of the Roche NT-proBNP assay and comparison to the Biosite Triage BNP assay.
  Clinica chimica acta; international journal of clinical chemistry 2003 Yeo KT, Wu AH, Apple FS, Kroll MH, Christenson RH, Lewandrowski KB, Sedor FA, Butch AW
• Quantitative analysis and prognostic implication of SARS coronavirus RNA in the plasma and serum of patients with severe acute respiratory syndrome.
  Clinical chemistry 2003 Ng EK, Hui DS, Chan KC, Hung EC, Chiu RW, Lee N, Wu A, Chim SS, Tong YK, Sung JJ, Tam JS, Lo YM
• Severe acute respiratory syndrome-associated coronavirus infection.
  Emerging infectious diseases 2003 Chan PK, Ip M, Ng KC, Rickjason CW, Wu A, Lee N, Rainer TH, Joynt GM, Sung JJ, Tam JS
• Biological variation for N-terminal pro- and B-type natriuretic peptides and implications for therapeutic monitoring of patients with congestive heart failure.
  The American journal of cardiology 2003 Wu AH, Smith A, Wieczorek S, Mather JF, Duncan B, White CM, McGill C, Katten D, Heller G
• Human metapneumovirus detection in patients with severe acute respiratory syndrome.
  Emerging infectious diseases 2003 Chan PK, Tam JS, Lam CW, Chan E, Wu A, Li CK, Buckley TA, Ng KC, Joynt GM, Cheng FW, To KF, Lee N, Hui DS, Cheung JL, Chu I, Liu E, Chung SS, Sung JJ
• Imaging of severe acute respiratory syndrome in Hong Kong.
  AJR. American journal of roentgenology 2003 Antonio GE, Wong KT, Hui DS, Lee N, Yuen EH, Wu A, Chung SS, Sung JJ, Ahuja AT
• Prognostic value of the Ortho Vitros cardiac troponin I assay in patients with symptoms of myocardial ischemia. Risk stratification using European Society of Cardiology/American College of Cardiology recommended cutoff values.
  American journal of clinical pathology 2003 Apple FS, Murakami MM, Quist HH, Pearce LA, Wieczorek S, Wu AH
• Haematological manifestations in patients with severe acute respiratory syndrome: retrospective analysis.
  BMJ (Clinical research ed.) 2003 Wong RS, Wu A, To KF, Lee N, Lam CW, Wong CK, Chan PK, Ng MH, Yu LM, Hui DS, Tam JS, Cheng G, Sung JJ
• Thin-section CT in patients with severe acute respiratory syndrome following hospital discharge: preliminary experience.
  Radiology 2003 Antonio GE, Wong KT, Hui DS, Wu A, Lee N, Yuen EH, Leung CB, Rainer TH, Cameron P, Chung SS, Sung JJ, Ahuja AT
• Bedside B-Type natriuretic peptide in the emergency diagnosis of heart failure with reduced or preserved ejection fraction. Results from the Breathing Not Properly Multinational Study.
  Journal of the American College of Cardiology 2003 Maisel AS, McCord J, Nowak RM, Hollander JE, Wu AH, Duc P, Omland T, Storrow AB, Krishnaswamy P, Abraham WT, Clopton P, Steg G, Aumont MC, Westheim A, Knudsen CW, Perez A, Kamin R, Kazanegra R, …
• Plasticizers, antioxidants, and other contaminants found in air delivered by PVC tubing used in respiratory therapy.
  Biomedical chromatography : BMC 2003 Hill SS, Shaw BR, Wu AH
• The ischemia-modified albumin biomarker for myocardial ischemia.
  MLO: medical laboratory observer 2003 Wu AH
• Severe acute respiratory syndrome: radiographic appearances and pattern of progression in 138 patients.
  Radiology 2003 Wong KT, Antonio GE, Hui DS, Lee N, Yuen EH, Wu A, Leung CB, Rainer TH, Cameron P, Chung SS, Sung JJ, Ahuja AT
• Thin-section CT of severe acute respiratory syndrome: evaluation of 73 patients exposed to or with the disease.
  Radiology 2003 Wong KT, Antonio GE, Hui DS, Lee N, Yuen EH, Wu A, Leung CB, Rainer TH, Cameron P, Chung SS, Sung JJ, Ahuja AT
• Stability of cholesterol gall stones after 165 years of burial.
  Journal of forensic sciences 2003 Wu AH, Bellantoni NF
• A major outbreak of severe acute respiratory syndrome in Hong Kong.
  The New England journal of medicine 2003 Lee N, Hui D, Wu A, Chan P, Cameron P, Joynt GM, Ahuja A, Yung MY, Leung CB, To KF, Lui SF, Szeto CC, Chung S, Sung JJ
• B-type natriuretic peptide and renal function in the diagnosis of heart failure: an analysis from the Breathing Not Properly Multinational Study.
  American journal of kidney diseases : the official journal of the National Kidney Foundation 2003 McCullough PA, Duc P, Omland T, McCord J, Nowak RM, Hollander JE, Herrmann HC, Steg PG, Westheim A, Knudsen CW, Storrow AB, Abraham WT, Lamba S, Wu AH, Perez A, Clopton P, Krishnaswamy P, Kazanegra R,…
• National academy of clinical biochemistry laboratory medicine practice guidelines: recommendations for the use of laboratory tests to support poisoned patients who present to the emergency department.
  Clinical chemistry 2003 Wu AH, McKay C, Broussard LA, Hoffman RS, Kwong TC, Moyer TP, Otten EM, Welch SL, Wax P, National Academy of Clinical Biochemistry Laboratory Medicine
• Uncovering heart failure in patients with a history of pulmonary disease: rationale for the early use of B-type natriuretic peptide in the emergency department.
  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2003 McCullough PA, Hollander JE, Nowak RM, Storrow AB, Duc P, Omland T, McCord J, Herrmann HC, Steg PG, Westheim A, Knudsen CW, Abraham WT, Lamba S, Wu AH, Perez A, Clopton P, Krishnaswamy P, Kazanegra R,…
• A 24-hour comparison of serum growth hormone concentrations in patients with heart failure versus healthy controls.
  Pharmacotherapy 2003 Duncan B, Moyna NM, Heller GV, McGill C, Katten D, Finta L, Velusamy M, Kelsey A, Wieczorek S, Wu AH, White CM
• BNP test utilization for CHF in community hospital practice.
  Clinica chimica acta; international journal of clinical chemistry 2003 Apple FS, Trinity E, Steen J, Prawer S, Wu AH
• Correlation of B-type natriuretic peptide level to 6-min walk test performance in patients with left ventricular systolic dysfunction.
  Clinica chimica acta; international journal of clinical chemistry 2003 Wieczorek SJ, Hager D, Barry MB, Kearney L, Ferrier A, Wu AH
• Signify ER Drug Screen Test evaluation: comparison to Triage Drug of Abuse Panel plus tricyclic antidepressants.
  Clinica chimica acta; international journal of clinical chemistry 2003 Phillips JE, Bogema S, Fu P, Furmaga W, Wu AH, Zic V, Hammett-Stabler C
• European Society of Cardiology and American College of Cardiology guidelines for redefinition of myocardial infarction: how to use existing assays clinically and for clinical trials.
  American heart journal 2002 Apple FS, Wu AH, Jaffe AS
• B-type natriuretic peptide and clinical judgment in emergency diagnosis of heart failure: analysis from Breathing Not Properly (BNP) Multinational Study.
  Circulation 2002 McCullough PA, Nowak RM, McCord J, Hollander JE, Herrmann HC, Steg PG, Duc P, Westheim A, Omland T, Knudsen CW, Storrow AB, Abraham WT, Lamba S, Wu AH, Perez A, Clopton P, Krishnaswamy P, Kazanegra R,…
• Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure.
  The New England journal of medicine 2002 Maisel AS, Krishnaswamy P, Nowak RM, McCord J, Hollander JE, Duc P, Omland T, Storrow AB, Abraham WT, Wu AH, Clopton P, Steg PG, Westheim A, Knudsen CW, Perez A, Kazanegra R, Herrmann HC, McCullough …
• Guidelines and recommendations in laboratory medicine.
  Clinical chemistry 2002 Wu AH, Valdes R, Hawker CD
• Cardiac markers: cost-effective triage for MI admission and therapy.
  MLO: medical laboratory observer 2002 Wu AH
• Long-term follow-up of patients with increased cardiac troponin concentrations following percutaneous coronary intervention.
  The American journal of cardiology 2002 Wu AH, Boden WE, McKay RG
• Multicenter evaluation of an automated assay for troponin I.
  Clinical chemistry 2002 Uettwiller-Geiger D, Wu AH, Apple FS, Jevans AW, Venge P, Olson MD, Darte C, Woodrum DL, Roberts S, Chan S
• False-positive phencyclidine immunoassay results caused by venlafaxine and O-desmethylvenlafaxine.
  Clinical chemistry 2002 Sena SF, Kazimi S, Wu AH