Aida Venado Estrada, MD
Associate Professor
Medicine
School of Medicine

Dr. Venado is a Pulmonary and Critical Care physician who specializes in treating patients with interstitial lung disease and patients with advanced lung disease who undergo lung transplantation.

Research and Quality Activities In collaboration with the transplant team at UCSF, she described the natural history of frailty in patients that undergo lung transplantation. She found that pre-operative frailty rapidly improves in the six months following lung transplant. Dr. Venado and the UCSF team then demonstrated that frailty after lung transplant is associated with increased mortality and found that transplant-related complications, such as renal disease, obesity, and malnutrition, can induce frailty. Dr. Venado is the founder of the Quality in Lung Transplant Care (QUILT) initiative at UCSF, which leverages real-world data monitoring to aim for care that preserves lung allograft function with the least possible complications of immunosuppression. Dr. Venado serves as the Director for Quality and Safety for the Pulmonary Division at UCSF.

Activities to support Diversity As a native Spanish speaker, Dr. Venado aims to overcome language and cultural barriers when caring for Latinx patients with advanced lung disease and lung transplant recipients. Dr. Venado served as co-chair for the Women in Pulmonary Medicine group at UCSF.

• CCR5 drives NK cell-associated airway damage in pulmonary ischemia-reperfusion injury.
  JCI insight 2023 Santos J, Wang P, Shemesh A, Liu F, Tsao T, Aguilar OA, Cleary SJ, Singer JP, Gao Y, Hays SR, Golden JA, Leard L, Kleinhenz ME, Kolaitis NA, Shah R, Venado A, Kukreja J, Weigt SS, Belperio JA, Lanier …
• The Association Between Frailty and Chronic Lung Allograft Dysfunction After Lung Transplantation.
  Transplantation 2023 Singer JP, Gao Y, Huang CY, Kordahl RC, Sriram A, Hays SR, Kukreja J, Venado A, Calabrese DR, Greenland JR
• Development of the Lung Transplant Frailty Scale (LT-FS).
  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2023 Singer JP, Christie JD, Diamond JM, Anderson MA, Benvenuto LA, Gao Y, Arcasoy SM, Lederer DJ, Calabrese D, Wang P, Hays SR, Kukreja J, Venado A, Kolaitis NA, Leard LE, Shah RJ, Kleinhenz ME, Golden J,…
• Subphenotypes of frailty in lung transplant candidates.
  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2023 Singer JP, Calfee CS, Delucchi K, Diamond JM, Anderson MA, Benvenuto LA, Gao Y, Wang P, Arcasoy SM, Lederer DJ, Hays SR, Kukreja J, Venado A, Kolaitis NA, Leard LE, Shah RJ, Kleinhenz ME, Golden J, …
• Design and implementation of a digital health home spirometry intervention for remote monitoring of lung transplant function.
  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2023 Odisho AY, Liu AW, Maiorano AR, Bigazzi MOA, Medina E, Leard LE, Shah R, Venado A, Perez A, Golden J, Kleinhenz ME, Kolaitis NA, Maheshwari J, Trinh BN, Kukreja J, Greenland J, Calabrese D, Neinstein …
• NKG2D receptor activation drives primary graft dysfunction severity and poor lung transplantation outcomes.
  JCI insight 2022 Calabrese DR, Tsao T, Magnen M, Valet C, Gao Y, Mallavia B, Tian JJ, Aminian EA, Wang KM, Shemesh A, Punzalan EB, Sarma A, Calfee CS, Christenson SA, Langelier CR, Hays SR, Golden JA, Leard LE, …
• Extracellular Matrix Stiffness in Lung Health and Disease.
  Comprehensive Physiology 2022 Guo T, He C, Venado A, Zhou Y
• Chronic Lung Allograft Dysfunction.
  Thoracic surgery clinics 2022 Venado A, Kukreja J, Greenland JR
• Depressive symptoms in lung transplant recipients: trajectory and association with mortality and allograft dysfunction.
  Thorax 2022 Kolaitis NA, Gao Y, Soong A, Greenland JR, Hays SR, Golden JA, Venado A, Leard LE, Shah RJ, Kleinhenz ME, Katz PP, Kukreja J, Blanc PD, Smith PJ, Singer JP
• Construct and Predictive Validity of Sarcopenia in Lung Transplant Candidates.
  Annals of the American Thoracic Society 2021 Maheshwari JA, Kolaitis NA, Anderson MR, Benvenuto L, Gao Y, Katz PP, Greenland J, Wolters PJ, Covinsky K, Hays SR, Kukreja J, Calabrese DR, Venado A, Shah RJ, Leard LE, Trinh B, Huang CY, Glidden D, …
• ISHLT consensus document on lung transplantation in patients with connective tissue disease: Part I: Epidemiology, assessment of extrapulmonary conditions, candidate evaluation, selection criteria, and pathology statements.
  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2021 Crespo MM, Lease ED, Sole A, Sandorfi N, Snyder LD, Berry GJ, Pavec JL, Venado AE, Cifrian JM, Goldberg H, Dilling DF, Gries C, Nair A, Willie K, Meyer KC, Shah RJ, Tokman S, Holm A, Patterson CM, …
• The association of post-operative delirium with patient-reported outcomes and mortality after lung transplantation.
  Clinical transplantation 2021 DeBolt CL, Gao Y, Sutter N, Soong A, Leard L, Jeffrey G, Kleinhenz ME, Calabrese D, Greenland J, Venado A, Hays SR, Shah R, Kukreja J, Trinh B, Kolaitis NA, Douglas V, Diamond JM, Smith P, Singer J
• Strategies for forming effective women's groups.
  The clinical teacher 2020 Santhosh L, Harleman E, Venado A, Farrand E, E Gilbreth M, Keenan BP, Thompson VV, Shah RJ
• Primary graft dysfunction attenuates improvements in health-related quality of life after lung transplantation, but not disability or depression.
  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2020 Kolaitis NA, Gao Y, Soong A, Greenland JR, Hays SR, Golden J, Leard LE, Shah RJ, Kleinhenz ME, Katz PP, Venado A, Kukreja J, Blanc PD, Singer JP
• Recurrent Pulmonary Fibrosis in a Lung Allograft Secondary to De Novo Antisynthetase Syndrome.
  Annals of the American Thoracic Society 2020 Scallan C, Venado A, Han L, Xu H, Mulligan M, Raghu G
• Frailty after lung transplantation is associated with impaired health-related quality of life and mortality.
  Thorax 2020 Venado A, Kolaitis NA, Huang CY, Gao Y, Glidden DV, Soong A, Sutter N, Katz PP, Greenland JR, Calabrese DR, Hays SR, Golden JA, Shah RJ, Leard LE, Kukreja J, Deuse T, Wolters PJ, Covinsky K, Blanc PD,…
• Diaphragmatic Atrophy May Limit Progression of Idiopathic Pulmonary Fibrosis.
  American journal of respiratory and critical care medicine 2020 Venado A, Witt LJ, Kallianos K, Wolters PJ
• Improvements in frailty contribute to substantial improvements in quality of life after lung transplantation in patients with cystic fibrosis.
  Pediatric pulmonology 2020 Perez AA, Hays SR, Soong A, Gao Y, Greenland JR, Leard LE, Shah RJ, Golden J, Kukreja J, Venado A, Kleinhenz ME, Singer JP
• Longitudinal assessment of interstitial lung disease in single lung transplant recipients with scleroderma.
  Rheumatology (Oxford, England) 2020 Hinze AM, Lin CT, Hussien AF, Perin J, Venado A, Golden JA, Boin F, Brown RH, Wise RA, Wigley FM
• Mitochondrial DNA Stimulates TLR9-Dependent Neutrophil Extracellular Trap Formation in Primary Graft Dysfunction.
  American journal of respiratory cell and molecular biology 2020 Mallavia B, Liu F, Lefrançais E, Cleary SJ, Kwaan N, Tian JJ, Magnen M, Sayah DM, Soong A, Chen J, Saggar R, Shino MY, Ross DJ, Derhovanessian A, Lynch JP, Ardehali A, Weigt SS, Belperio JA, Hays SR, …
• Tacrolimus trough monitoring guided by mass spectrometry without accounting for assay differences is associated with acute kidney injury in lung transplant recipients.
  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 2019 Kolaitis NA, Calabrese DR, Ahearn P, Venado A, Florez R, Lei HL, Isaak K, Henricksen E, Martinez E, Chong T, Shah RJ, Leard LE, Kleinhenz ME, Golden J, De Marco T, Greenland JR, Kukreja J, Hays SR, …
• Management and clinical outcomes after lung transplantation in patients with pre-transplant Mycobacterium abscessus infection: A single center experience.
  Transplant infectious disease : an official journal of the Transplantation Society 2019 Perez AA, Singer JP, Schwartz BS, Chin-Hong P, Shah RJ, Kleinhenz ME, Gao Y, Venado A, Leard LE, Golden JA, Kukreja J, Greenland JR, Hays SR
• Frailty phenotypes and mortality after lung transplantation: A prospective cohort study.
  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2018 Singer JP, Diamond JM, Anderson MR, Katz PP, Covinsky K, Oyster M, Blue T, Soong A, Kalman L, Shrestha P, Arcasoy SM, Greenland JR, Shah L, Kukreja J, Blumenthal NP, Easthausen I, Golden JA, McBurnie …
• Mechanosensing by the α6-integrin confers an invasive fibroblast phenotype and mediates lung fibrosis.
  Nature communications 2016 Chen H, Qu J, Huang X, Kurundkar A, Zhu L, Yang N, Venado A, Ding Q, Liu G, Antony VB, Thannickal VJ, Zhou Y
• Unexplained hemolysis in patients undergoing ECMO: beware of hypertriglyceridemia.
  Perfusion 2014 Venado A, Wille K, Belott SC, Diaz-Guzman E
• Protocol-based treatment of septic shock, fibrinolysis for submassive pulmonary embolism, and use of corticosteroids in acute exacerbations of chronic obstructive pulmonary disease requiring mechanical ventilation.
  American journal of respiratory and critical care medicine 2014 Sharma N, Venado A, Morrison J
• Prolonged extracorporeal membrane oxygenation use as a bridge to lung transplantation: it is time for a national registry.
  Chest 2014 Venado A, Hoopes CW, Diaz-Guzman E
• Alcohol ingestion disrupts alveolar epithelial barrier function by activation of macrophage-derived transforming growth factor beta1.
  Respiratory research 2013 Curry-McCoy TV, Venado A, Guidot DM, Joshi PC
• Images in clinical medicine. Unexpected swallowing of a knife.
  The New England journal of medicine 2012 Venado A, Prebil S
• On the spread of the novel influenza A (H1N1) virus in Mexico.
  Journal of infection in developing countries 2009 López-Cervantes M, Venado A, Moreno A, Pacheco-Domínguez RL, Ortega-Pierres G
• [Past and future of the Revista de Investigación Clínica].
  Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 2008 Gamba G, García-Romero MT, Venado A