Agnieszka Ciesielska, PhD
Postdoctoral Scholar
Business Service Ctr
Chancellor/EVC/FAS

Websites

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• Profile at UCSF Department of Neurological Surgery (neurosurgery.ucsf.edu)

Publications (39)

Top publication keywords:
CarbidopaCorpus StriatumGenetic VectorsAromatic-L-Amino-Acid DecarboxylasesCaudate NucleusPutamenOxidopamineParkinson DiseaseMPTP PoisoningDopamineImmunity, CellularGlial Cell Line-Derived Neurotrophic FactorParkinsonian DisordersAxonal TransportDependovirus

• Modified human mesenchymal stromal/stem cells restore cortical excitability after focal ischemic stroke in rats.
  Molecular therapy : the journal of the American Society of Gene Therapy 2024 Klein B, Ciesielska A, Losada PM, Sato A, Shah-Morales S, Ford JB, Higashikubo B, Tager D, Urry A, Bombosch J, Chang WC, Andrews-Zwilling Y, Nejadnik B, Warraich Z, Paz JT
• Enhancing GAT-3 in thalamic astrocytes promotes resilience to brain injury in rodents.
  Science translational medicine 2022 Cho FS, Vainchtein ID, Voskobiynyk Y, Morningstar AR, Aparicio F, Higashikubo B, Ciesielska A, Broekaart DWM, Anink JJ, van Vliet EA, Yu X, Khakh BS, Aronica E, Molofsky AV, Paz JT
• Gamma rhythms and visual information in mouse V1 specifically modulated by somatostatin+ neurons in reticular thalamus.
  eLife 2021 Hoseini MS, Higashikubo B, Cho FS, Chang AH, Clemente-Perez A, Lew I, Ciesielska A, Stryker MP, Paz JT
• Cerebral administration of alpha-synuclein monomers modulates inflammatory reaction in nigro-striatal system.
  Journal of Pre-Clinical and Clinical Research 2019 Anna Sznejder-Pacholek, Ilona Joniec-Maciejak, Adriana Wawer, Agnieszka Ciesielska, Dagmara Mirowska-Guzel
• Effects of α-Synuclein Monomers Administration in the Gigantocellular Reticular Nucleus on Neurotransmission in Mouse Model.
  Neurochemical research 2019 Joniec-Maciejak I, Ciesielska A, Poniatowski LA, Wawer A, Sznejder-Pacholek A, Wojnar E, Maciejak P, Mirowska-Guzel D

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• Depletion of AADC activity in caudate nucleus and putamen of Parkinson's disease patients; implications for ongoing AAV2-AADC gene therapy trial.
  PloS one 2017 Ciesielska A, Samaranch L, San Sebastian W, Dickson DW, Goldman S, Forsayeth J, Bankiewicz KS
• The effect of α-synuclein on gliosis and IL-1α, TNFα, IFNγ, TGFβ expression in murine brain.
  Pharmacological reports : PR 2016 Sznejder-Pacholek A, Joniec-Maciejak I, Wawer A, Ciesielska A, Mirowska-Guzel D
• Structural and Physicochemical Studies of Olopatadine Hydrochloride Conformational Polymorphs.
  Journal of pharmaceutical sciences 2016 Laszcz M, Trzcinska K, Witkowska A, Ciesielska A, Badowska-Roslonek K, Kuziak K
• Widespread AAV1- and AAV2-mediated transgene expression in the nonhuman primate brain: implications for Huntington's disease.
  Molecular therapy. Methods & clinical development 2016 Hadaczek P, Stanek L, Ciesielska A, Sudhakar V, Samaranch L, Pivirotto P, Bringas J, O'Riordan C, Mastis B, San Sebastian W, Forsayeth J, Cheng SH, Bankiewicz KS, Shihabuddin LS
• Exogenous α-Synuclein Monomers Alter Dopamine Metabolism in Murine Brain.
  Neurochemical research 2016 Wawer A, Joniec-Maciejak I, Sznejder-Pacholek A, Schwenkgrub J, Ciesielska A, Mirowska-Guzel D
• 621. Widespread Gene Delivery to the Nonhuman Primate Brain for the Treatment of Huntington's Disease.
  Molecular Therapy 2016 Piotr Hadaczek, Lisa Stanek, Agnieszka Ciesielska, Philip Pivirotto, Catherine O'Riordan, Bryan Mastis, Waldy San Sebastian, John Forsayeth, Seng H. Cheng, Krystof S. Bankiewicz, Lamya S. Shihabuddin
• SYNTHESIS AND CYTOTOXIC ACTIVITY OF NEW 5H-INDOLO[2,3-B]QUINOLINE O-AMINOGLYCOSIDES.
  Acta poloniae pharmaceutica 2016 Badowska-Roslonek K, Ciesielska A, Switalska M, Piskozub M, Peczynska-Czoch W, Wietrzyk J, Kaczmarek L
• Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT(1A) activity. Part 5.
  European journal of medicinal chemistry 2015 Gomólka A, Ciesielska A, Wróbel MZ, Chodkowski A, Kleps J, Dawidowski M, Siwek A, Wolak M, Stachowicz K, Slawinska A, Nowak G, Satala G, Bojarski AJ, Belka M, Ulenberg S, Baczek T, Skowronek P, Turlo …
• 454. Prior AAV2-hIL10 Infusion Decreases AAV9-Dependent Immunotoxicity in Rat Brain.
  Molecular Therapy 2015 Agnieszka Ciesielska, Piotr Hadaczek, Janine Beyer, John Forsayeth, Krystof Bankiewicz
• Carbidopa-based modulation of the functional effect of the AAV2-hAADC gene therapy in 6-OHDA lesioned rats.
  PloS one 2015 Ciesielska A, Sharma N, Beyer J, Forsayeth J, Bankiewicz K
• GDNF signaling implemented by GM1 ganglioside; failure in Parkinson's disease and GM1-deficient murine model.
  Experimental neurology 2014 Hadaczek P, Wu G, Sharma N, Ciesielska A, Bankiewicz K, Davidow AL, Lu ZH, Forsayeth J, Ledeen RW
• SAFETY AND TOLERABILITY OF MRI-GUIDED INFUSION OF AAV2-hAADC INTO THE MID-BRAIN OF NON-HUMAN PRIMATE.
  Molecular therapy. Methods & clinical development 2014 San Sebastian W, Kells AP, Bringas J, Samaranch L, Hadaczek P, Ciesielska A, Macayan M, Pivirotto PJ, Forsayeth J, Osborne S, Wright JF, Green F, Heller G, Bankiewicz KS
• Specific binding of gibberellic acid by cytokinin-specific binding proteins: a new aspect of plant hormone-binding proteins with the PR-10 fold.
  Acta crystallographica. Section D, Biological crystallography 2014 Ruszkowski M, Sliwiak J, Ciesielska A, Barciszewski J, Sikorski M, Jaskolski M
• The influence of AAV2-mediated gene transfer of human IL-10 on neurodegeneration and immune response in a murine model of Parkinson's disease.
  Pharmacological reports : PR 2014 Joniec-Maciejak I, Ciesielska A, Wawer A, Sznejder-Pacholek A, Schwenkgrub J, Cudna A, Hadaczek P, Bankiewicz KS, Czlonkowska A, Czlonkowski A
• Effect of human interleukin-10 on the expression of nitric oxide synthases in the MPTP-based model of Parkinson's disease.
  Pharmacological reports : PR 2013 Schwenkgrub J, Joniec-Maciejak I, Sznejder-Pacholek A, Wawer A, Ciesielska A, Bankiewicz K, Czlonkowska A, Czlonkowski A
• Cerebral infusion of AAV9 vector-encoding non-self proteins can elicit cell-mediated immune responses.
  Molecular therapy : the journal of the American Society of Gene Therapy 2012 Ciesielska A, Hadaczek P, Mittermeyer G, Zhou S, Wright JF, Bankiewicz KS, Forsayeth J
• Anterograde axonal transport of AAV2-GDNF in rat basal ganglia.
  Molecular therapy : the journal of the American Society of Gene Therapy 2010 Ciesielska A, Mittermeyer G, Hadaczek P, Kells AP, Forsayeth J, Bankiewicz KS
• The impact of age and gender on the striatal astrocytes activation in murine model of Parkinson's disease.
  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2009 Ciesielska A, Joniec I, Kurkowska-Jastrzebska I, Cudna A, Przybylkowski A, Czlonkowska A, Czlonkowski A
• Age- and sex-differences in the nitric oxide synthase expression and dopamine concentration in the murine model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
  Brain research 2009 Joniec I, Ciesielska A, Kurkowska-Jastrzebska I, Przybylkowski A, Czlonkowska A, Czlonkowski A
• Influence of age and gender on cytokine expression in a murine model of Parkinson's disease.
  Neuroimmunomodulation 2008 Ciesielska A, Joniec I, Kurkowska-Jastrzebska I, Przybylkowski A, Gromadzka G, Czlonkowska A, Czlonkowski A
• [Catheter malposition in the renal vein--a rare complication related to a peripherally inserted central catheter].
  Kardiologia polska 2007 Josiak K, Mysiak A, Kobusiak-Prokopowicz M, Ciesielska A, Kurcz J
• 2.452 CD4+ anti-MOG lymphocytes administration improves recovery after MPTP induced injury in mice model of Parkinson's disease.
  Parkinsonism & Related Disorders 2007 I. Kurkowska-Jastrzebska, A. Ciesielska, C. Möller, M. Zaremba, A. Czlonkowski, A. Czlonkowska
• APOE does not predict poor outcome 1 year after ischemic stroke.
  Neurological research 2007 Sarzynska-Dlugosz I, Gromadzka G, Baranska-Gieruszczak M, Ciesielska A, Czlonkowska A
• Dopamine, serotonin and noradrenaline changes in the striatum of C57BL mice following myelin oligodendrocyte glycoprotein (MOG) 35-55 and complete Freund adjuvant (CFA) administration.
  Acta neurobiologiae experimentalis 2007 Balkowiec-Iskra E, Kurkowska-Jastrzebska I, Joniec I, Ciesielska A, Czlonkowska A, Czlonkowski A
• P5 ROLE OF CYTOKINES IN MURINE MODEL OF PARKINSON'S DISEASE - GENDER AND AGE-RELATED DIFFERENCES.
  Behavioural Pharmacology 2006 A. Ciesielska, I. Joniec, A. Przybylkowski, I. Kurkowska-Jastrzbska, A. Czonkowska, A. Czonkowski
• P6 CORRELATION BETWEEN NOS EXPRESSION AND DOPAMINE CONCENTRATION IN THE STRIATUM OF C57BL/6 MICE FOLLOWING TOXIC DEGENERATION CAUSED BY 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE.
  Behavioural Pharmacology 2006 I. Joniec, A. Ciesielska, A. Przybylkowski, I. Kurkowska-Jastrzbska, A. Czonkowska, A. Czonkowski
• [Successful percutaneous angioplasty of renal artery in a patient with severe arterial hypertension and symptoms of hyperaldosteronism: a case report].
  Kardiologia polska 2006 Skrzypiec-Spring M, Spring A, Poczatek K, Nowicki P, Derkacz A, Ciesielska A, Negrusz-Kawecka M, Mazurek W
• Gender differences in neurological disease: role of estrogens and cytokines.
  Endocrine 2006 Czlonkowska A, Ciesielska A, Gromadzka G, Kurkowska-Jastrzebska I
• APOE genotype and serum cholesterol in predicting risk for early death from ischemic stroke in men and women.
  Cerebrovascular diseases (Basel, Switzerland) 2005 Gromadzka G, Baranska-Gieruszczak M, Ciesielska A, Sarzynska-Dlugosz I, Czlonkowska A
• Dexamethasone protects against dopaminergic neurons damage in a mouse model of Parkinson's disease.
  International immunopharmacology 2004 Kurkowska-Jastrzebska I, Litwin T, Joniec I, Ciesielska A, Przybylkowski A, Czlonkowski A, Czlonkowska A
• Cyclooxygenases mRNA and protein expression in striata in the experimental mouse model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration to mouse.
  Brain research 2004 Przybylkowski A, Kurkowska-Jastrzebska I, Joniec I, Ciesielska A, Czlonkowska A, Czlonkowski A
• Influence of estrogens on neurodegenerative processes.
  Medical science monitor : international medical journal of experimental and clinical research 2003 Czlonkowska A, Ciesielska A, Joniec I
• Dynamics of expression of the mRNA for cytokines and inducible nitric synthase in a murine model of the Parkinson's disease.
  Acta neurobiologiae experimentalis 2003 Ciesielska A, Joniec I, Przybylkowski A, Gromadzka G, Kurkowska-Jastrzebska I, Czlonkowska A, Czlonkowski A
• [Immunosuppressive aspects of estrogen].
  Neurologia i neurochirurgia polska 2003 Ciesielska A