Adam Staffaroni, PhD
Associate Professor
Neurology
School of Medicine

Dr. Staffaroni is a clinical neuropsychologist and Associate Professor at the UCSF Memory and Aging Center. His research focuses on improving early detection, prognosis, and monitoring of neurodegenerative diseases through a combination of clinical tests, neuroimaging, and blood-based biomarkers. He leads studies of remote digital data collection in frontotemporal dementia using smartphone assessments and sensor technologies.

Grants and Projects

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• Validating remote digital assessments for familial frontotemporal dementia, NIH/NIA, 2022-2025
• Optimizing Clinical Trial Endpoints in Frontotemporal Dementia, NIH, 2019-2024
• Infrastructure for FTD Data Integration, Visualization and Analysis, Bluefield Project to Cure FTD, 2023
• Using a Smartphone Application to Study Frontotemporal Lobar Degeneration, Bluefield Project to Cure FTD, 2021-2023

Publications (167)

Top publication keywords:
Cognitive AgingWhite MatterEarly DiagnosisAtrophyCognitive DysfunctionNeurodegenerative Diseasestau ProteinsAlzheimer DiseaseFrontotemporal DementiaAgingFrontotemporal Lobar DegenerationMemory, EpisodicExecutive FunctionC9orf72 ProteinNeuropsychological Tests

• Development and validation of the Uniform Data Set (v3.0) executive function composite score (UDS3-EF).
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Staffaroni AM, Asken BM, Casaletto KB, Fonseca C, You M, Rosen HJ, Boxer AL, Elahi FM, Kornak J, Mungas D, Kramer JH
• Rates of Brain Atrophy Across Disease Stages in Familial Frontotemporal Dementia Associated With MAPT, GRN, and C9orf72 Pathogenic Variants.
  JAMA network open 2020 Staffaroni AM, Goh SM, Cobigo Y, Ong E, Lee SE, Casaletto KB, Wolf A, Forsberg LK, Ghoshal N, Graff-Radford NR, Grossman M, Heuer HW, Hsiung GR, Kantarci K, Knopman DS, Kremers WK, Mackenzie IR, …
• Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degeneration.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Staffaroni AM, Cobigo Y, Goh SM, Kornak J, Bajorek L, Chiang K, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dever R, Dheel C, Dickerson BC, Dickinson S, Dominguez S, …
• Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Staffaroni AM, Bajorek L, Casaletto KB, Cobigo Y, Goh SM, Wolf A, Heuer HW, Elahi FM, Ljubenkov PA, Dever R, Kornak J, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dheel…
• A longitudinal characterization of perfusion in the aging brain and associations with cognition and neural structure.
  Human brain mapping 2019 Staffaroni AM, Cobigo Y, Elahi FM, Casaletto KB, Walters SM, Wolf A, Lindbergh CA, Rosen HJ, Kramer JH
• Longitudinal multimodal imaging and clinical endpoints for frontotemporal dementia clinical trials.
  Brain : a journal of neurology 2019 Staffaroni AM, Ljubenkov PA, Kornak J, Cobigo Y, Datta S, Marx G, Walters SM, Chiang K, Olney N, Elahi FM, Knopman DS, Dickerson BC, Boeve BF, Gorno-Tempini ML, Spina S, Grinberg LT, Seeley WW, Miller…
• The Longitudinal Trajectory of Default Mode Network Connectivity in Healthy Older Adults Varies As a Function of Age and Is Associated with Changes in Episodic Memory and Processing Speed.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Staffaroni AM, Brown JA, Casaletto KB, Elahi FM, Deng J, Neuhaus J, Cobigo Y, Mumford PS, Walters S, Saloner R, Karydas A, Coppola G, Rosen HJ, Miller BL, Seeley WW, Kramer JH

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• From "invisible" to "audible": Features extracted during simple speech tasks classify patient-reported fatigue in multiple sclerosis.
  Multiple sclerosis (Houndmills, Basingstoke, England) 2024 Nylander A, Sisodia N, Henderson K, Wijangco J, Koshal K, Poole S, Dias M, Linz N, Tröger J, König A, Hayward-Koennecke H, Pedotti R, Brown E, Halabi C, Staffaroni A, Bove R
• Sexually dimorphic differences in angiogenesis markers are associated with brain aging trajectories in humans.
  Science translational medicine 2024 Torres-Espin A, Radabaugh HL, Treiman S, Fitzsimons SS, Harvey D, Chou A, Lindbergh CA, Casaletto KB, Goldberger L, Staffaroni AM, Maillard P, Miller BL, DeCarli C, Hinman JD, Ferguson AR, Kramer JH, …
• Biological validation of peak-width of skeletonized mean diffusivity as a VCID biomarker: The MarkVCID Consortium.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2024 Luckey AM, Ghosh S, Wang CP, Beiser A, Bernal R, Li Z, Mbangdadji D, Fadaee E, Snoussi H, Dediós AGV, Trevino HA, Goss M, Hillmer LJ, Bauer CE, Staffaroni AM, Stables L, Albert M, Himali JJ, Mosley TH…
• Neuropsychiatric Symptoms Cluster and Fluctuate Over Time in Behavioral Variant Frontotemporal Dementia.
  medRxiv : the preprint server for health sciences 2024 Morrow CB, Kamath V, Dickerson BC, Eldaief M, Rezaii N, Wong B, McGinnis S, Darby R, Staffaroni AM, Lapid MI, Pascual B, Rojas JC, Masdeu JC, Tsapkini K, Huey ED, Fisher DW, Pantelyat A, Balaji A, Sah…
• Gene-Specific Effects on Brain Volume and Cognition of TMEM106B in Frontotemporal Lobar Degeneration.
  Neurology 2024 Vandebergh M, Ramos EM, Corriveau-Lecavalier N, Ramanan VK, Kornak J, Mester C, Kolander T, Brushaber DE, Staffaroni AM, Geschwind DH, Wolf AA, Kantarci K, Gendron T, Petrucelli L, Van den Broeck M, …
• A framework for translating tauopathy therapeutics: Drug discovery to clinical trials.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2024 Feldman HH, Cummings JL, Boxer AL, Staffaroni AM, Knopman DS, Sukoff Rizzo SJ, Territo PR, Arnold SE, Ballard C, Beher D, Boeve BF, Dacks PA, Diaz K, Ewen C, Fiske B, Gonzalez MI, Harris GA, Hoffman …
• Better cardiovascular health is associated with slowed clinical progression in autosomal dominant frontotemporal lobar degeneration variant carriers.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2024 VandeBunte AM, Lee H, Paolillo EW, Hsiung GR, Staffaroni AM, Saloner R, Tartaglia C, Yaffe K, Knopman DS, Ramos EM, Rascovsky K, Bozoki AC, Wong B, Domoto-Reilly K, Snyder A, Pressman P, Mendez MF, …
• Clinical implications of head trauma in frontotemporal dementia and primary progressive aphasia.
  Alzheimer's research & therapy 2024 Asken BM, Bove JM, Bauer RM, Tanner JA, Casaletto KB, Staffaroni AM, VandeVrede L, Alosco ML, Mez JB, Stern RA, Miller BL, Grinberg LT, Boxer AL, Gorno-Tempini ML, Rosen HJ, Rabinovici GD, Kramer JH
• Subjective Cognitive Complaints and Anecdotal Descriptions of Postoperative Cognitive Decline: Missing Pieces of the Postoperative Neurocognitive Disorder Puzzle.
  Advances in anesthesia 2024 Li LY, Staffaroni AM, Whitlock EL
• Predicting brain atrophy and cognitive aging trajectories with baseline subjective cognitive concerns in cognitively normal older adults.
  Neurobiology of aging 2024 You M, Lindbergh CA, La Joie R, Paolillo EW, Saloner R, Diaz V, Cotter DL, Walters S, Altendahl M, Staffaroni AM, Kramer JH, Gaynor LS, Casaletto KB
• CSF Proteomics in Patients With Progressive Supranuclear Palsy.
  Neurology 2024 Wise A, Li J, Yamakawa M, Loureiro J, Peterson B, Worringer K, Sivasankaran R, Palma JA, Mitic L, Heuer HW, Lario-Lago A, Staffaroni AM, Clark A, Taylor J, Ljubenkov PA, Vandevrede L, Grinberg LT, …
• Examining Associations Between Smartphone Use and Clinical Severity in Frontotemporal Dementia: Proof-of-Concept Study.
  JMIR aging 2024 Paolillo EW, Casaletto KB, Clark AL, Taylor JC, Heuer HW, Wise AB, Dhanam S, Sanderson-Cimino M, Saloner R, Kramer JH, Kornak J, Kremers W, Forsberg L, Appleby B, Bayram E, Bozoki A, Brushaber D, …
• Associations of cerebrovascular disease and Alzheimer's disease pathology with cognitive decline: Analysis of the National Alzheimer's Coordinating Center Uniform Data Set.
  Neurobiology of aging 2024 Chatterjee A, Lee S, Diaz V, Saloner R, Sanderson-Cimino M, deCarli C, Maillard P, Hinman J, Vossel K, Casaletto KB, Staffaroni AM, Paolillo EW, Kramer JH
• Digital Facial Analysis Correlates with Mood and Cognitive Outcomes with People with MS (P6-6.013).
  Neurology 2024 Alyssa Nylander, Kyra Henderson, Kanishka Koshal, Nikki Sisodia, Jaeleene Wijangco, Shane Poole, Jim Rowson, Cathra Halabi, Ethan Brown, Katherine Possin, Adam Staffaroni, Riley Bove
• Face Validity: Digital Facial Analysis Recapitulates Clinical Findings of Neurological Disease (P10-4.002).
  Neurology 2024 Alyssa Nylander, Kyra Henderson, Kanishka Koshal, Nikki Sisodia, Jaeleene Wijangco, Shane Poole, Jim Rowson, Cathra Halabi, Jill Ostrem, Simon Little, Ethan Brown, Adam Staffaroni, Riley Bove
• Gene specific effects on brain volume and cognition of TMEM106B in frontotemporal lobar degeneration.
  medRxiv : the preprint server for health sciences 2024 Vandebergh M, Ramos EM, Corriveau-Lecavalier N, Ramanan VK, Kornak J, Mester C, Kolander T, Brushaber D, Staffaroni AM, Geschwind D, Wolf A, Kantarci K, Gendron TF, Petrucelli L, Van den Broeck M, …
• Reliability and Validity of Smartphone Cognitive Testing for Frontotemporal Lobar Degeneration.
  JAMA network open 2024 Staffaroni AM, Clark AL, Taylor JC, Heuer HW, Sanderson-Cimino M, Wise AB, Dhanam S, Cobigo Y, Wolf A, Manoochehri M, Forsberg L, Mester C, Rankin KP, Appleby BS, Bayram E, Bozoki A, Clark D, Darby RR…
• Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration.
  Research square 2024 Saloner R, Staffaroni A, Dammer E, Johnson ECB, Paolillo E, Wise A, Heuer H, Forsberg L, Lago AL, Webb J, Vogel J, Santillo A, Hansson O, Kramer J, Miller B, Li J, Loureiro J, Sivasankaran R, …
• Clinicopathological correlation of cerebrospinal fluid alpha-synuclein seed amplification assay in a behavioral neurology autopsy cohort.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2024 Samudra N, Fischer DL, Lenio S, Lario Lago A, Ljubenkov PA, Rojas JC, Seeley WW, Spina S, Staffaroni AM, Tablante J, Wekselman F, Lamoureux J, Concha-Marambio L, Grinberg LT, Boxer AL, VandeVrede L
• Linking Type and Extent of Head Trauma to Cavum Septum Pellucidum in Older Adults With and Without Alzheimer Disease and Related Dementias.
  Neurology 2024 Asken BM, Tanner JA, Vandevrede L, Apple A, Chapleau M, Gaynor LS, Lane-Donovan C, Lenio S, Yadollahikhales G, Lee S, Gontrum E, Knudtson M, Iaccarino L, La Joie R, Cobigo Y, Staffaroni AM, Casaletto …
• Cognitive function influences cognitive-motor interference during dual task walking in multiple sclerosis.
  Multiple sclerosis and related disorders 2024 Hsu WY, Block VJ, Wijangco J, Henderson K, Nylander A, Koshal K, Poole S, Possin KL, Staffaroni AM, Bove RM
• Building a normative sample for smartphone-based measures of cognition and motor functioning: Study design and initial feasibility findings.
  Alzheimer's & Dementia 2023 Sreya Dhanam, Adam M. Staffaroni, Jack C Taylor, Mark E. Sanderson-Cimino, Amy B. Wise, Annie L Clark, Hilary W. Heuer, Winnie Kwang, Joel H. Kramer, Brad F. Boeve, Howard J. Rosen, Michael S. W. …
• Clinical value of CSF TMEM106B in familial and sporadic frontotemporal lobar degeneration.
  Alzheimer's & Dementia 2023 Julio C. Rojas, Yann Cobigo, Amy B. Wise, Jingyao Li, Joseph Loureiro, Katie Worringer, Hilary W. Heuer, Peter A. Ljubenkov, Lawren VandeVrede, Adam M. Staffaroni, Argentina Lario Lago, Eliana Marisa …
• Functional connectivity trajectories in genetic frontotemporal dementia.
  Alzheimer's & Dementia 2023 Liwen Zhang, Taru M. Flagan, Adam M. Staffaroni, Suvi Häkkinen, Jesse A. Brown, Maria Luisa Mandelli, Howard J. Rosen, Kejal Kantarci, Eliana Marisa Ramos, Maria Luisa Gorno Tempini, Bruce L Miller, …
• Global platform trial design for tau (MAPT) mutation carriers.
  Alzheimer's & Dementia 2023 Adam M. Staffaroni, Melanie Quintana, Barbara Wendelberger, Carmela Tartaglia, Hilary W. Heuer, Lucy L. Russell, Tania F Gendron, Leonard Petrucelli, Carolin Heller, Amy Wolf, Yann Cobigo, Mark E. …
• Leveraging Large-scale CSF Proteomics to identify Disease Progression Biomarkers in Autosomal Dominant Frontotemporal Lobar Degeneration.
  Alzheimer's & Dementia 2023 Rowan Saloner, Adam M. Staffaroni, Eric B. Dammer, Erik C.B. Johnson, Emily W. Paolillo, Hilary W. Heuer, Amy B. Wise, Leah K. Forsberg, Joel H. Kramer, Bruce L Miller, Jingyao Li, Joseph Loureiro, …
• Life’s Simple 7 Relates to Better Cognitive and Brain Health in Individuals with Autosomal Dominant Frontotemporal Dementia.
  Alzheimer's & Dementia 2023 Anna M VandeBunte, Joel H. Kramer, Kaitlin B. Casaletto, Emily W. Paolillo, Rowan Saloner, Hyunwoo Lee, Ging-Yuek Robin Hsiung, Adam M. Staffaroni, Shannon Y. Lee, Carmela Tartaglia, Hilary W. Heuer, …
• Memory Performance in Mild Sporadic and Familial Behavioral Variant Frontotemporal Dementia: Findings from the ALLFTD Consortium.
  Alzheimer's & Dementia 2023 Brad F. Boeve, Julie A. Fields, Jeremy A. Syrjanen, Noah Johnson, Walter K. Kremers, Adam M. Staffaroni, Edward D. Huey, Katya Rascovsky, Sandra Weintraub, Eliana Marisa Ramos, David S. Knopman, Toji …
• PSMD, a novel biomarker of small vessel disease, and its association with cognitive function — A comprehensive clinical validation study.
  Alzheimer's & Dementia 2023 Alison M. Luckey, Saptaparni Ghosh, Rebecca Bernal, Haykel Snoussi, Angel G. Velarde, Hector Trevino, Monica Goss, Jayandra Jung Himali, Laura J. Hillmer, Hanzhang Lu, Konstantinos Arfanakis, Brian T.…
• Passively monitored smartphone battery percentage relates to disease severity in frontotemporal dementia: A proof-of-concept study.
  Alzheimer's & Dementia 2023 Emily W. Paolillo, Kaitlin B. Casaletto, Annie L Clark, Jack C Taylor, Hilary W. Heuer, Amy B. Wise, Sreya Dhanam, Mark E. Sanderson-Cimino, Rowan Saloner, Joel H. Kramer, John Kornak, Walter K. …
• The Role of Alzheimer’s Disease Pathology in Cognition, Brain Volume, and Plasma Biomarker Concentrations in Traumatic Encephalopathy Syndrome.
  Alzheimer's & Dementia 2023 Breton M. Asken, Jeremy A. Tanner, Lawren VandeVrede, William G Mantyh, Kaitlin B. Casaletto, Adam M. Staffaroni, David N. soleimani-Meigooni, Leslie S Gaynor, Corrina S. Fonseca, Ranjani Shankar, …
• The relationship of intraindividual variability on mobile cognitive testing with age and frontotemporal dementia disease severity.
  Alzheimer's & Dementia 2023 Mark E. Sanderson-Cimino, Annie L Clark, Amy B. Wise, Sreya Dhanam, Jack C Taylor, Emily W. Paolillo, Hilary W. Heuer, Jason J. Hassenstab, Joel H. Kramer, Brad F. Boeve, Howard J. Rosen, Adam L. …
• Unobtrusive In-Home Digital Monitoring of Frontotemporal Dementia: Feasibility and Adherence.
  Alzheimer's & Dementia 2023 Amy B. Wise, Emily W. Paolillo, Zachary T Beattie, Chao-Yi Wu, Nathaniel Rodrigues, Sarah Gothard, Hilary W. Heuer, Leah K. Forsberg, Diana Chavez, Kelsey Holiday, Mario F. Mendez, Brad F. Boeve, Adam…
• Validation of Cerebrospinal Fluid Alpha-synuclein Assay against Autopsy in Non-Parkinson’s Disease Neurodegenerative Syndromes.
  Alzheimer's & Dementia 2023 Niyatee Samudra, Peter A. Ljubenkov, Julio C. Rojas, Adam M. Staffaroni, Fattin Wekselman, Lamoureux Jennifer, Lea T. Grinberg, Adam L. Boxer, Lawren VandeVrede
• Functional connectivity trajectories in genetic frontotemporal dementia.
  Alzheimer's & Dementia 2023 Liwen Zhang, Taru M. Flagan, Adam M. Staffaroni, Suvi Häkkinen, Jesse A. Brown, Maria Luisa Mandelli, Howard J. Rosen, Kejal Kantarci, Eliana Marisa Ramos, Maria Luisa Gorno Tempini, Bruce L Miller, …
• Functional network collapse in neurodegenerative disease.
  bioRxiv : the preprint server for biology 2023 Brown JA, Lee AJ, Fernhoff K, Pistone T, Pasquini L, Wise AB, Staffaroni AM, Luisa Mandelli M, Lee SE, Boxer AL, Rankin KP, Rabinovici GD, Luisa Gorno Tempini M, Rosen HJ, Kramer JH, Miller BL, Seeley…
• 50 Effects of Cerebrovascular Risk Factors and Alzheimer’s Disease Pathology on Executive Function and Memory Changes: Analysis of the National Alzheimer’s Coordinating Center Cohort.
  Journal of the International Neuropsychological Society 2023 Ankita Chatterjee, Shannon Lee, Valentina Diaz, Kaitlin B Casaletto, Adam M Staffaroni, Joel H Kramer
• 6 Remote Smartphone Cognitive and Motor Testing in Frontotemporal Dementia Research: Feasibility, Reliability, and Validity.
  Journal of the International Neuropsychological Society 2023 Adam M Staffaroni, Jack Carson Taylor, Annie L Clark, Hilary W Heuer, Amy B Wise, Masood Manoochehri, Leah Forsberg, Carly T Mester, Meghana Roa, Danielle Brushaber, Julio C Rojas, Joel H Kramer, …
• 93 Impact of Cardiovascular Risk on Cognitive and Brain Aging in Autosomal Dominant Frontotemporal Dementia.
  Journal of the International Neuropsychological Society 2023 Anna M VandeBunte, Emily W Paolillo, Hyunwoo Lee, Ging-Yuek Robin Hsiung, Adam Staffaroni, Shannon Y Lee, Carmela Tartaglia, Hilary Heur, Joel H Kramer, Brad Boeve, Adam Boxer, Howie Rosen, Kaitlin B …
• Alzheimer's pathology is associated with altered cognition, brain volume, and plasma biomarker patterns in traumatic encephalopathy syndrome.
  Alzheimer's research & therapy 2023 Asken BM, Tanner JA, Gaynor LS, VandeVrede L, Mantyh WG, Casaletto KB, Staffaroni AM, Fonseca C, Shankar R, Grant H, Smith K, Lago AL, Xu H, La Joie R, Cobigo Y, Rosen H, Perry DC, Rojas JC, Miller BL…
• Sexually dimorphic differences in angiogenesis markers predict brain aging trajectories.
  bioRxiv : the preprint server for biology 2023 Torres-Espin A, Rabadaugh H, Fitzsimons S, Harvey D, Chou A, Lindberg C, Casaletto KB, Goldberger L, Staffaroni AM, Maillard P, Miller BL, DeCarli C, Hinman JD, Ferguson AR, Kramer JH, Elahi FM
• MRI free water as a biomarker for cognitive performance: Validation in the markvcid consortium.
  Alzheimer's & Dementia 2023 Pauline Maillard, Laura J. Hillmer, Hanzhang Lu, Konstantinos Arfanakis, Brian T. Gold, Christopher E. Bauer, Joel H. Kramer, Adam M. Staffaroni, Lara Stables, Danny J.J. Wang, Sudha Seshadri, Claudia…
• Phenoconversion and disease progression observed in mutation carriers of familial Frontotemporal Lobar Degeneration in the ALLFTD Consortium.
  Alzheimer's & Dementia 2023 Hilary W. Heuer, Annie L Clark, Danielle Brushaber, Leah K. Forsberg, Toji Miyagawa, Adam M. Staffaroni, Edward D. Huey, Brad F. Boeve, Howard J. Rosen, Adam L. Boxer, ALLFTD Investigators
• Feasibility and acceptability of remote smartphone cognitive testing in frontotemporal dementia research.
  Alzheimer's & dementia (Amsterdam, Netherlands) 2023 Taylor JC, Heuer HW, Clark AL, Wise AB, Manoochehri M, Forsberg L, Mester C, Rao M, Brushaber D, Kramer J, Welch AE, Kornak J, Kremers W, Appleby B, Dickerson BC, Domoto-Reilly K, Fields JA, Ghoshal N…
• Evaluation of Plasma Phosphorylated Tau217 for Differentiation Between Alzheimer Disease and Frontotemporal Lobar Degeneration Subtypes Among Patients With Corticobasal Syndrome.
  JAMA neurology 2023 VandeVrede L, La Joie R, Thijssen EH, Asken BM, Vento SA, Tsuei T, Baker SL, Cobigo Y, Fonseca C, Heuer HW, Kramer JH, Ljubenkov PA, Rabinovici GD, Rojas JC, Rosen HJ, Staffaroni AM, Boeve BF, …
• Remote Digital Technologies for the Early Detection and Monitoring of Cognitive Decline in Patients With Type 2 Diabetes: Insights From Studies of Neurodegenerative Diseases.
  Journal of diabetes science and technology 2023 DuBord AY, Paolillo EW, Staffaroni AM
• Memory Performance in Asymptomatic and Prodromal Familial Frontotemporal Lobar Degeneration: Findings from the ALLFTD Consortium (P13-6.001).
  Neurology 2023 Bradley Boeve, Julie Fields, Jeremy Syrjanen, Walter Kremers, Adam Staffaroni, Edward Huey, Katya Rascovsky, Marisa Ramos, Leah Forsberg, Hilary Heuer, Adam Boxer, Howard Rosen
• Plasma inflammation for predicting phenotypic conversion and clinical progression of autosomal dominant frontotemporal lobar degeneration.
  Journal of neurology, neurosurgery, and psychiatry 2023 Asken BM, Ljubenkov PA, Staffaroni AM, Casaletto KB, Vandevrede L, Cobigo Y, Rojas-Rodriguez JC, Rankin KP, Kornak J, Heuer H, Shigenaga J, Appleby BS, Bozoki AC, Domoto-Reilly K, Ghoshal N, Huey E, …
• Multisite ALLFTD study modeling progressive empathy loss from the earliest stages of behavioral variant frontotemporal dementia.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 Toller G, Cobigo Y, Callahan P, Appleby BS, Brushaber D, Domoto-Reilly K, Forsberg LK, Ghoshal N, Graff-Radford J, Graff-Radford NR, Grossman M, Heuer HW, Kornak J, Kremers W, Lapid MI, Leger G, …
• ALLFTD Mobile App Balance and Finger Tapping Tasks: Task Description and Initial Reliability and Validity Findings.
  Alzheimer's & Dementia 2022 Amy B Wise, Annie L Clark, Jack C Taylor, Hilary W. Heuer, Carly T. Mester, Meghana Rao, Danielle Brushaber, Bradley F. Boeve, Leah K. Forsberg, Joel H. Kramer, Howard J. Rosen, Adam L Boxer, Adam M. …
• Baseline Reliability and Six-Month Stability of a Remotely Administered Battery of Smartphone Cognitive Tests.
  Alzheimer's & Dementia 2022 Jack C Taylor, Annie L Clark, Hilary W. Heuer, Amy B Wise, Masood Manoochehri, Leah K. Forsberg, Carly T. Mester, Meghana Rao, Danielle Brushaber, Joel H. Kramer, Bradley F. Boeve, Howard J. Rosen, …
• Construct Validity of the ALLFTD Mobile App Cognitive Tests: Associations with Gold Standard Clinical Measures and Brain Volume.
  Alzheimer's & Dementia 2022 Adam M. Staffaroni, Annie L Clark, Jack C Taylor, Hilary W. Heuer, Amy B Wise, Masood Manoochehri, Leah K. Forsberg, Carly T. Mester, Meghana Rao, Danielle Brushaber, Julio C. Rojas, Joel H. Kramer, …
• Introduction to Veri-T: A Phase 1 Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial of Verdiperstat in Patients with svPPA Due to FTLD-TDP.
  Alzheimer's & Dementia 2022 Peter A. Ljubenkov, Adam M. Staffaroni, Julio C. Rojas, Lawren VandeVrede, Mary Koestler, Tayler A Sulse, Julia Moreton, Sheena Horiki, Hilary W. Heuer, Ian Grant, David J. Irwin, Bradley F. Boeve, …
• Sex modifies the association between hippocampal blood flow and episodic memory in cognitively unimpaired individuals.
  Alzheimer's & Dementia 2022 Anna Brugulat-Serrat, Yann Cobigo, Corrina S. Fonseca, Torie Tsuei, Lauren Goldberger, Howard J. Rosen, Joel H. Kramer, Fanny M Elahi, Adam M. Staffaroni, Kaitlin B Casaletto
• The Collaboration and Harmonization of Digital Biomarkers for Alzheimer’s Research.
  Alzheimer's & Dementia 2022 Zachary T Beattie, Sarah Gothard, Lisa L. Barnes, Shayla Calloway, Mitzi M Gonzales, Brian D Jones, Tiffany F Kautz, Allan I. Levey, Julia J Mathews, Rachel Mulavelil, Brenna Phelps, Howard J. Rosen, …
• The Collaboration and Harmonization of Digital Biomarkers for Alzheimer’s Research.
  Alzheimer's & Dementia 2022 Zachary T Beattie, Sarah Gothard, Lisa L. Barnes, Shayla Calloway, Mitzi M Gonzales, Brian D Jones, Tiffany F Kautz, Allan I. Levey, Julia J Mathews, Rachel Mulavelil, Brenna Phelps, Howard J. Rosen, …
• MRI free water as a biomarker for cognitive performance: Validation in the MarkVCID consortium.
  Alzheimer's & dementia (Amsterdam, Netherlands) 2022 Maillard P, Hillmer LJ, Lu H, Arfanakis K, Gold BT, Bauer CE, Kramer JH, Staffaroni AM, Stables L, Wang DJJ, Seshadri S, Satizabal CL, Beiser A, Habes M, Fornage M, Mosley TH, Rosenberg GA, Singh B, …
• Age-related brain atrophy is not a homogenous process: Different functional brain networks associate differentially with aging and blood factors.
  Proceedings of the National Academy of Sciences of the United States of America 2022 Markov NT, Lindbergh CA, Staffaroni AM, Perez K, Stevens M, Nguyen K, Murad NF, Fonseca C, Campisi J, Kramer J, Furman D
• Temporal order of clinical and biomarker changes in familial frontotemporal dementia.
  Nature medicine 2022 Staffaroni AM, Quintana M, Wendelberger B, Heuer HW, Russell LL, Cobigo Y, Wolf A, Goh SM, Petrucelli L, Gendron TF, Heller C, Clark AL, Taylor JC, Wise A, Ong E, Forsberg L, Brushaber D, Rojas JC, …
• Detection of emerging neurodegeneration using Bayesian linear mixed-effect modeling.
  NeuroImage. Clinical 2022 Cobigo Y, Goh MS, Wolf A, Staffaroni AM, Kornak J, Miller BL, Rabinovici GD, Seeley WW, Spina S, Boxer AL, Boeve BF, Wang L, Allegri R, Farlow M, Mori H, Perrin RJ, Kramer J, Rosen HJ, Alzheimer’s …
• Sensitivity of the Social Behavior Observer Checklist to Early Symptoms of Patients With Frontotemporal Dementia.
  Neurology 2022 Toller G, Cobigo Y, Ljubenkov PA, Appleby BS, Dickerson BC, Domoto-Reilly K, Fong JC, Forsberg LK, Gavrilova RH, Ghoshal N, Heuer HW, Knopman DS, Kornak J, Lapid MI, Litvan I, Lucente DE, Mackenzie IR…
• Retinal arteriolar parameters as a surrogate marker of intracranial vascular pathology.
  Alzheimer's & dementia (Amsterdam, Netherlands) 2022 Abdelhak A, Solomon I, Montes SC, Saias A, Cordano C, Asken B, Fonseca C, Oertel FC, Arfanakis K, Staffaroni AM, Kramer JH, Geschwind M, Miller BL, Elahi FM, Green AJ
• Multi-Modal Biomarkers of Repetitive Head Impacts and Traumatic Encephalopathy Syndrome: A Clinicopathological Case Series.
  Journal of neurotrauma 2022 Asken BM, Tanner JA, VandeVrede L, Casaletto KB, Staffaroni AM, Mundada N, Fonseca C, Iaccarino L, La Joie R, Tsuei T, Mladinov M, Grant H, Shankar R, Wang KKW, Xu H, Cobigo Y, Rosen H, Gardner RC, …
• Plasma P-tau181 and P-tau217 in Patients With Traumatic Encephalopathy Syndrome With and Without Evidence of Alzheimer Disease Pathology.
  Neurology 2022 Asken BM, Tanner JA, VandeVrede L, Mantyh WG, Casaletto KB, Staffaroni AM, La Joie R, Iaccarino L, Soleimani-Meigooni D, Rojas JC, Gardner RC, Miller BL, Grinberg LT, Boxer AL, Kramer JH, Rabinovici …
• Proposed research criteria for prodromal behavioural variant frontotemporal dementia.
  Brain : a journal of neurology 2022 Barker MS, Gottesman RT, Manoochehri M, Chapman S, Appleby BS, Brushaber D, Devick KL, Dickerson BC, Domoto-Reilly K, Fields JA, Forsberg LK, Galasko DR, Ghoshal N, Goldman J, Graff-Radford NR, …
• Association of Genetic Variants Linked to Late-Onset Alzheimer Disease With Cognitive Test Performance by Midlife.
  JAMA network open 2022 Zimmerman SC, Brenowitz WD, Calmasini C, Ackley SF, Graff RE, Asiimwe SB, Staffaroni AM, Hoffmann TJ, Glymour MM
• Cross-national harmonization of cognitive measures across HRS HCAP (USA) and LASI-DAD (India).
  PloS one 2022 Vonk JMJ, Gross AL, Zammit AR, Bertola L, Avila JF, Jutten RJ, Gaynor LS, Suemoto CK, Kobayashi LC, O'Connell ME, Elugbadebo O, Amofa PA, Staffaroni AM, Arce Rentería M, Turney IC, Jones RN, Manly JJ,…
• Author Correction: Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans.
  Scientific reports 2022 Elahi FM, Harvey D, Altendahl M, Brathaban N, Fernandes N, Casaletto KB, Staffaroni AM, Maillard P, Hinman JD, Miller BL, DeCarli C, Kramer JH, Goetzl EJ
• A remote smartphone cognitive testing battery for frontotemporal dementia: Completion rate, reliability, and validity.
  Alzheimer's & Dementia 2021 Adam M. Staffaroni, Jack C Taylor, Annie L Clark, Hilary W. Heuer, Leah K. Forsberg, Riley Bahl, Masood Manoochehri, Stephanie Vento, Lynn P. Bajorek, Elise Ong, Michelle You, Bradley F. Boeve, Joel H…
• Changes in wall thickness of retinal arterioles as a surrogate marker of intracranial vascular pathology.
  Alzheimer's & Dementia 2021 Ahmed Abdelhak, Isaac Solomon, Alexandra Saias, Shivany Condor Montes, Christian Cordano, Breton Asken, Corrina Fonseca, Frederike Cosima Oertel, Konstantinos Arfanakis, Adam M. Staffaroni, Michael …
• Clinical features that differentiate young-onset AD from young-onset FTLD: An examination of the NACC UDS 3.0 and FTLD Module.
  Alzheimer's & Dementia 2021 Sheena Isha Dev, Bonnie Wong, Megan Quimby, Ani Eloyan, Adam M. Staffaroni, Katya Rascovsky, Sandra Weintraub, Julie A. Fields, Katherine P Rankin, Walter A. Kukull, Hilary W. Heuer, Leah K. Forsberg,…
• Disease progression models of familial frontotemporal lobar degeneration and the temporal ordering of biomarker changes in an international cohort.
  Alzheimer's & Dementia 2021 Adam M. Staffaroni, Melanie Quintana, Barbara Wendelberger, Lucy L. Russell, Leonard Petrucelli, Tania F. Gendron, Sheng-Yang Matthew Goh, Yann Cobigo, Amy Wolf, Hilary W. Heuer, David M. Cash, Elise …
• Sex differences in the behavioral variant of frontotemporal dementia: A new window to executive and behavioral reserve.
  Alzheimer's & Dementia 2021 Ignacio Illán-Gala, Kaitlin B. Casaletto, Sergi Borrego-Écija, Eider M Arenaza-Urquijo, Amy Wolf, Yann Cobigo, Sheng-Yang Matthew Goh, Adam M. Staffaroni, Daniel Alcolea, Juan Fortea, Rafael Blesa, …
• Clinical value of CSF tau, p-tau181, neurogranin and neurofilaments in familial frontotemporal lobar degeneration.
  Alzheimer's & Dementia 2021 Julio C. Rojas, Hilary W. Heuer, Weiping Chen, Julie Czerkowicz, Danielle Graham, Leah K. Forsberg, Danielle Brushaber, Brian Appleby, Eliana Marisa Ramos, Giovanni Coppolla, Yvette M. Bordelon, Hugo …
• Demographic and psychosocial factors associated with the decision to learn mutation status in familial frontotemporal dementia and the impact of disclosure on mood.
  Alzheimer's & Dementia 2021 Lynn P. Bajorek, Rachel Kiekhofer, Matthew Hall, Joanne Taylor, Diane E Lucente, Danielle Brushaber, Brian Appleby, Giovanni Coppolla, Yvette M Bordelon, Hugo Botha, Brad C Dickerson, Dennis W Dickson…
• Diagnostic value of plasma P-tau217 in frontotemporal dementia spectrum disorders.
  Alzheimer's & Dementia 2021 Julio C. Rojas, Lawren Vandevrede, Hilary W. Heuer, Gianina Toller, Elisabeth H. Thijssen, Nicholas Proctor, Leah K. Forsberg, Danielle Brushaber, Eliana Marisa Ramos, Giovanni Coppola, Brian Appleby,…
• Gearing up for the future: Exploring facilitators and barriers to inform clinical trial design in frontotemporal lobar degeneration.
  Alzheimer's & Dementia 2021 Yasmin B Banga, Yujung Lai, Priscilla Kim, Bradley F Boeve, Adam L Boxer, Howard J Rosen, Leah K Forsberg, Hilary W Heuer, Danielle Brushaber, Brian Appleby, Joanna M Biernacka, Yvette M Bordelon, …
• Interbatch Reliability of Blood-Based Cytokine and Chemokine Measurements in Community-Dwelling Older Adults: A Cross-Sectional Study.
  The journals of gerontology. Series A, Biological sciences and medical sciences 2021 Lindbergh CA, Asken BM, Casaletto KB, Elahi FM, Goldberger LA, Fonseca C, You M, Apple AC, Staffaroni AM, Fitch R, Rivera Contreras W, Wang P, Karydas A, Kramer JH, Hillblom Aging Network
• Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans.
  Scientific reports 2021 Elahi FM, Harvey D, Altendahl M, Brathaban N, Fernandes N, Casaletto KB, Staffaroni AM, Maillard P, Hinman JD, Miller BL, DeCarli C, Kramer JH, Goetzl EJ
• Pattern and degree of individual brain atrophy predicts dementia onset in dominantly inherited Alzheimer's disease.
  Alzheimer's & dementia (Amsterdam, Netherlands) 2021 Keret O, Staffaroni AM, Ringman JM, Cobigo Y, Goh SM, Wolf A, Allen IE, Salloway S, Chhatwal J, Brickman AM, Reyes-Dumeyer D, Bateman RJ, Benzinger TLS, Morris JC, Ances BM, Joseph-Mathurin N, Perrin …
• Building clinically relevant outcomes across the Alzheimer's disease spectrum.
  Alzheimer's & dementia (New York, N. Y.) 2021 Rentz DM, Wessels AM, Annapragada AV, Berger AK, Edgar CJ, Gold M, Miller DS, Randolph C, Ryan JM, Wunderlich G, Zoschg MC, Trépel D, Knopman DS, Staffaroni AM, Bain LJ, Carrillo MC, Weber CJ
• Lower White Matter Volume and Worse Executive Functioning Reflected in Higher Levels of Plasma GFAP among Older Adults with and Without Cognitive Impairment.
  Journal of the International Neuropsychological Society : JINS 2021 Asken BM, VandeVrede L, Rojas JC, Fonseca C, Staffaroni AM, Elahi FM, Lindbergh CA, Apple AC, You M, Weiner-Light S, Brathaban N, Fernandes N, Boxer AL, Miller BL, Rosen HJ, Kramer JH, Casaletto KB
• Retinal imaging demonstrates reduced capillary density in clinically unimpaired APOE ε4 gene carriers.
  Alzheimer's & dementia (Amsterdam, Netherlands) 2021 Elahi FM, Ashimatey SB, Bennett DJ, Walters SM, La Joie R, Jiang X, Wolf A, Cobigo Y, Staffaroni AM, Rosen HJ, Miller BL, Rabinovici GD, Kramer JH, Green AJ, Kashani AH
• Wisdom and fluid intelligence are dissociable in healthy older adults.
  International psychogeriatrics 2021 Lindbergh CA, Romero-Kornblum H, Weiner-Light S, Young JC, Fonseca C, You M, Wolf A, Staffaroni AM, Daly R, Jeste DV, Kramer JH, Chiong W, Hillblom Aging Network
• A Comparative Study of Plasma t-tau and Neurofilament Light Chain in Frontotemporal Lobar Degeneration and Alzheimer’s Disease (1305).
  Neurology 2021 Ignacio Illan-Gala, Alberto Lleo, Adam Staffaroni, Henrik Zetterberg, Agnieszka Kieloch, Lea Grinberg, Salvatore Spina, Joel Kramer, Eliana Marisa Ramos, Giovanni Coppola, Renaud La Joie, Gil …
• Characterization of a large single-site USA CADASIL cohort (2437).
  Neurology 2021 Jennifer Zitser-Koren, Daven Crossland, Theresa Driscoll, Michael Terranova, Sasha Saias, Jane Paulsen, Adam Staffaroni, Katherine Possin, Fanny Elahi, Michael Geschwind
• APOE moderates the effect of hippocampal blood flow on memory pattern separation in clinically normal older adults.
  Hippocampus 2021 Memel M, Staffaroni AM, Cobigo Y, Casaletto KB, Fonseca C, Bettcher BM, Yassa MA, Elahi FM, Wolf A, Rosen HJ, Kramer JH
• Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration.
  Neurology 2021 Rojas JC, Wang P, Staffaroni AM, Heller C, Cobigo Y, Wolf A, Goh SM, Ljubenkov PA, Heuer HW, Fong JC, Taylor JB, Veras E, Song L, Jeromin A, Hanlon D, Yu L, Khinikar A, Sivasankaran R, Kieloch A, …
• The Rapid Naming Test: Development and initial validation in typically aging adults.
  The Clinical neuropsychologist 2021 Stiver J, Staffaroni AM, Walters SM, You MY, Casaletto KB, Erlhoff SJ, Possin KL, Lukic S, La Joie R, Rabinovici GD, Zimmerman ME, Gorno-Tempini ML, Kramer JH
• Recognition memory and divergent cognitive profiles in prodromal genetic frontotemporal dementia.
  Cortex; a journal devoted to the study of the nervous system and behavior 2021 Barker MS, Manoochehri M, Rizer SJ, Appleby BS, Brushaber D, Dev SI, Devick KL, Dickerson BC, Fields JA, Foroud TM, Forsberg LK, Galasko DR, Ghoshal N, Graff-Radford NR, Grossman M, Heuer HW, Hsiung …
• Enhanced Stress Resilience Training in Surgeons: Iterative Adaptation and Biopsychosocial Effects in 2 Small Randomized Trials.
  Annals of surgery 2021 Lebares CC, Coaston TN, Delucchi KL, Guvva EV, Shen WT, Staffaroni AM, Kramer JH, Epel ES, Hecht FM, Ascher NL, Harris HW, Cole SW
• Uniform data set language measures for bvFTD and PPA diagnosis and monitoring.
  Alzheimer's & dementia (Amsterdam, Netherlands) 2021 Staffaroni AM, Weintraub S, Rascovsky K, Rankin KP, Taylor J, Fields JA, Casaletto KB, Hillis AE, Lukic S, Gorno-Tempini ML, Heuer H, Teylan MA, Kukull WA, Miller BL, Boeve BF, Rosen HJ, Boxer AL, …
• Sex differences in the behavioral variant of frontotemporal dementia: A new window to executive and behavioral reserve.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2021 Illán-Gala I, Casaletto KB, Borrego-Écija S, Arenaza-Urquijo EM, Wolf A, Cobigo Y, Goh SYM, Staffaroni AM, Alcolea D, Fortea J, Blesa R, Clarimon J, Iulita MF, Brugulat-Serrat A, Lladó A, Grinberg LT,…
• A novel temporal-predominant neuro-astroglial tauopathy associated with TMEM106B gene polymorphism in FTLD/ALS-TDP.
  Brain pathology (Zurich, Switzerland) 2021 Llibre-Guerra JJ, Lee SE, Suemoto CK, Ehrenberg AJ, Kovacs GG, Karydas A, Staffaroni A, Franca Resende EP, Kim EJ, Hwang JH, Ramos EM, Wojta KJ, Pasquini L, Pang SY, Spina S, Allen IE, Kramer J, …
• Mild Motor Signs Matter in Typical Brain Aging: The Value of the UPDRS Score Within a Functionally Intact Cohort of Older Adults.
  Frontiers in aging neuroscience 2021 Zitser J, Casaletto KB, Staffaroni AM, Sexton C, Weiner-Light S, Wolf A, Brown JA, Miller BL, Kramer JH
• Evaluation of Cerebral Blood Flow Measured by 3D PCASL as Biomarker of Vascular Cognitive Impairment and Dementia (VCID) in a Cohort of Elderly Latinx Subjects at Risk of Small Vessel Disease.
  Frontiers in neuroscience 2021 Jann K, Shao X, Ma SJ, Cen SY, D'Orazio L, Barisano G, Yan L, Casey M, Lamas J, Staffaroni AM, Kramer JH, Ringman JM, Wang DJJ
• Association of remote mild traumatic brain injury with cortical amyloid burden in clinically normal older adults.
  Brain imaging and behavior 2021 Asken BM, Mantyh WG, La Joie R, Strom A, Casaletto KB, Staffaroni AM, Apple AC, Lindbergh CA, Iaccarino L, You M, Grant H, Fonseca C, Windon C, Younes K, Tanner J, Rabinovici GD, Kramer JH, Gardner RC
• Plasma Glial Fibrillary Acidic Protein Levels Differ Along the Spectra of Amyloid Burden and Clinical Disease Stage.
  Journal of Alzheimer's disease : JAD 2021 Asken BM, Elahi FM, La Joie R, Strom A, Staffaroni AM, Lindbergh CA, Apple AC, You M, Weiner-Light S, Brathaban N, Fernandes N, Karydas A, Wang P, Rojas JC, Boxer AL, Miller BL, Rabinovici GD, Kramer …
• Multimodal MRI staging for tracking progression and clinical-imaging correlation in sporadic Creutzfeldt-Jakob disease.
  NeuroImage. Clinical 2020 Sacco S, Paoletti M, Staffaroni AM, Kang H, Rojas J, Marx G, Goh SY, Luisa Mandelli M, Allen IE, Kramer JH, Bastianello S, Henry RG, Rosen HJ, Caverzasi E, Geschwind MD
• Latent disease models estimate symptom onset in familial frontotemporal lobar degeneration and enable novel designs for early-stage clinical trials.
  Alzheimer's & Dementia 2020 Adam M. Staffaroni, Melanie Quintana, Barbara Wendelberger, Hilary W. Heuer, Julio C. Rojas, Yann Cobigo, Sheng-Yang Matthew Goh, Amy Wolf, Chiadi U. Onyike, Bradley F. Boeve, Howard J. Rosen, Adam L.…
• Neuropsychiatric abnormalities in familial frontotemporal dementia: Findings from the LEFFTDS Cohort.
  Alzheimer's & Dementia 2020 Leah K. Forsberg, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer, Jeremy Syrjanen, Danielle Brushaber, Giovanni Coppolla, Brad C. Dickerson, Julie A. Fields, Jamie Fong, Ralitza H. Gavrilova, Nupur …
• Pilot study of remote monitoring technologies for frontotemporal lobar degeneration (REMOTE FTLD): Feasibility and compliance.
  Alzheimer's & Dementia 2020 Jack Carson Taylor, Hilary W Heuer, Stephanie Vento, Lynn Bajorek, Elise Ong, Ping Wang, Michelle You, Howard J Rosen, Adam M Staffaroni, Adam L Boxer
• Plasma biomarkers of inflammation reflect disease state in autosomal dominant forms of familial frontotemporal dementia.
  Alzheimer's & Dementia 2020 Peter A. Ljubenkov, Adam M. Staffaroni, Kaitlin B. Casaletto, Julio C. Rojas, Lawren Vandevrede, Hilary W. Heuer, Fanny M. Elahi, Danielle Brushaber, Tatiana M. Foroud, Leah K. Forsberg, Anna M. …
• Studying the natural history of frontotemporal lobar degeneration (FTLD): The ARTFL LEFFTDS longitudinal FTLD (ALLFTD) protocol.
  Alzheimer's & Dementia 2020 Bradley F. Boeve, Adam L. Boxer, Howard J. Rosen, Leah K. Forsberg, Hilary W. Heuer, Danielle Brushaber, Brian Appleby, Joanna M. Biernacka, Yvette M. Bordelon, Hugo Botha, Patrick Brannelly, Brad C. …
• The evolution of brain atrophy across the disease spectrum of familial frontotemporal dementia.
  Alzheimer's & Dementia 2020 Adam M. Staffaroni, Sheng-Yang Matthew Goh, Yann Cobigo, Elise Ong, Suzee E. Lee, Kaitlin B. Casaletto, Amy Wolf, Leah K. Forsberg, Nupur Ghoshal, Neill R. Graff-Radford, Murray Grossman, Hilary W. …
• Tracking neurodegeneration in frontotemporal dementia and Alzheimer’s disease: A comparative study of plasma tau and neurofilament light chain.
  Alzheimer's & Dementia 2020 Ignacio Illán-Gala, Alberto Lleó, Anna M. Karydas, Adam M. Staffaroni, Henrik Zetterberg, Rajeev Sivasankaran, Lea Tenenholz Grinberg, Salvatore Spina, Joel H. Kramer, Eliana Marisa Ramos, Giovanni …
• Brain volumetric deficits in MAPT mutation carriers: a multisite study.
  Annals of clinical and translational neurology 2020 Chu SA, Flagan TM, Staffaroni AM, Jiskoot LC, Deng J, Spina S, Zhang L, Sturm VE, Yokoyama JS, Seeley WW, Papma JM, Geschwind DH, Rosen HJ, Boeve BF, Boxer AL, Heuer HW, Forsberg LK, Brushaber DE, …
• Plasma Tau and Neurofilament Light in Frontotemporal Lobar Degeneration and Alzheimer Disease.
  Neurology 2020 Illán-Gala I, Lleo A, Karydas A, Staffaroni AM, Zetterberg H, Sivasankaran R, Grinberg LT, Spina S, Kramer JH, Ramos EM, Coppola G, La Joie R, Rabinovici GD, Perry DC, Gorno-Tempini ML, Seeley WW, …
• Digital Cognitive Assessments for Dementia: Digital assessments may enhance the efficiency of evaluations in neurology and other clinics.
  Practical neurology (Fort Washington, Pa.) 2020 Staffaroni AM, Tsoy E, Taylor J, Boxer AL, Possin KL
• Worth the Wait: Delayed Recall after 1 Week Predicts Cognitive and Medial Temporal Lobe Trajectories in Older Adults.
  Journal of the International Neuropsychological Society : JINS 2020 Lindbergh CA, Walker N, La Joie R, Weiner-Light S, Staffaroni AM, Casaletto KB, Elahi F, Walters SM, You M, Cotter D, Asken B, Apple AC, Tsoy E, Neuhaus J, Fonseca C, Wolf A, Cobigo Y, Rosen H, Kramer…
• Sex-related differences in the relationship between β-amyloid and cognitive trajectories in older adults.
  Neuropsychology 2020 Lindbergh CA, Casaletto KB, Staffaroni AM, La Joie R, Iaccarino L, Edwards L, Tsoy E, Elahi F, Walters SM, Cotter D, You M, Apple AC, Asken B, Neuhaus J, Rexach JE, Wojta KJ, Rabinovici G, Kramer JH, …
• Salience Network Atrophy Links Neuron Type-Specific Pathobiology to Loss of Empathy in Frontotemporal Dementia.
  Cerebral cortex (New York, N.Y. : 1991) 2020 Pasquini L, Nana AL, Toller G, Brown JA, Deng J, Staffaroni A, Kim EJ, Hwang JL, Li L, Park Y, Gaus SE, Allen I, Sturm VE, Spina S, Grinberg LT, Rankin KP, Kramer JH, Rosen HJ, Miller BL, Seeley WW
• Baseline neuropsychological profiles in prion disease predict survival time.
  Annals of clinical and translational neurology 2020 Sundaram SE, Staffaroni AM, Walker NC, Casaletto KB, Casey M, Golubjatnikov A, Metcalf S, O'Leary K, Wong K, Benisano K, Forner S, Gonzalez Catalan M, Allen IE, Rosen HJ, Kramer JH, Geschwind MD
• Systemic Tumor Necrosis Factor-Alpha Trajectories Relate to Brain Health in Typically Aging Older Adults.
  The journals of gerontology. Series A, Biological sciences and medical sciences 2020 Lindbergh CA, Casaletto KB, Staffaroni AM, Elahi F, Walters SM, You M, Neuhaus J, Rivera Contreras W, Wang P, Karydas A, Brown J, Wolf A, Rosen H, Cobigo Y, Kramer JH
• REM sleep is associated with white matter integrity in cognitively healthy, older adults.
  PloS one 2020 Altendahl M, Cotter DL, Staffaroni AM, Wolf A, Mumford P, Cobigo Y, Casaletto K, Elahi F, Ruoff L, Javed S, Bettcher BM, Fox E, You M, Saloner R, Neylan TC, Kramer JH, Walsh CM
• Longitudinal structural and metabolic changes in frontotemporal dementia.
  Neurology 2020 Bejanin A, Tammewar G, Marx G, Cobigo Y, Iaccarino L, Kornak J, Staffaroni AM, Dickerson BC, Boeve BF, Knopman DS, Gorno-Tempini M, Miller BL, Jagust WJ, Boxer AL, Rosen HJ, Rabinovici GD
• Caregiver "objective attitude" toward patients with neurodegenerative disease: Consequences for caregiver strain and relationship closeness.
  Aging & mental health 2020 Zahir A, Staffaroni AM, Wickham RE, Quinn CM, Sapozhnikova A, Seidman J, Chiong W
• Aging and Positive Mood: Longitudinal Neurobiological and Cognitive Correlates.
  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2020 Cotter DL, Walters SM, Fonseca C, Wolf A, Cobigo Y, Fox EC, You MY, Altendahl M, Djukic N, Staffaroni AM, Elahi FM, Kramer JH, Casaletto KB, Hillblom Aging Network
• Sexual dimorphism of physical activity on cognitive aging: Role of immune functioning.
  Brain, behavior, and immunity 2020 Casaletto KB, Lindbergh C, Memel M, Staffaroni A, Elahi F, Weiner-Light S, You M, Fonseca C, Karydas A, Jacobs E, Dubal DB, Yaffe K, Kramer JH
• Revised Self-Monitoring Scale: A potential endpoint for frontotemporal dementia clinical trials.
  Neurology 2020 Toller G, Ranasinghe K, Cobigo Y, Staffaroni A, Appleby B, Brushaber D, Coppola G, Dickerson B, Domoto-Reilly K, Fields J, Fong J, Forsberg L, Ghoshal N, Graff-Radford N, Grossman M, Heuer H, Hsiung …
• Get Moving! Increases in Physical Activity Are Associated With Increasing Functional Connectivity Trajectories in Typically Aging Adults.
  Frontiers in aging neuroscience 2020 Dorsman KA, Weiner-Light S, Staffaroni AM, Brown JA, Wolf A, Cobigo Y, Walters S, Kramer JH, Casaletto KB
• Association of Cognitive and Behavioral Features Between Adults With Tuberous Sclerosis and Frontotemporal Dementia.
  JAMA neurology 2020 Liu AJ, Staffaroni AM, Rojas-Martinez JC, Olney NT, Alquezar-Burillo C, Ljubenkov PA, La Joie R, Fong JC, Taylor J, Karydas A, Ramos EM, Coppola G, Boxer AL, Rabinovici GD, Miller BL, Kao AW
• Differential cognitive substrates of verbal episodic memory performance in semantic variant primary progressive aphasia and Alzheimer's disease.
  Journal of neuropsychology 2020 DeVaughn S, Casaletto KB, Staffaroni AM, Wolf AA, Marx G, Kramer JH
• Clinical and volumetric changes with increasing functional impairment in familial frontotemporal lobar degeneration.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Olney NT, Ong E, Goh SM, Bajorek L, Dever R, Staffaroni AM, Cobigo Y, Bock M, Chiang K, Ljubenkov P, Kornak J, Heuer HW, Wang P, Rascovsky K, Wolf A, Appleby B, Bove J, Bordelon Y, Brannelly P, …
• Active lifestyles moderate clinical outcomes in autosomal dominant frontotemporal degeneration.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2020 Casaletto KB, Staffaroni AM, Wolf A, Appleby B, Brushaber D, Coppola G, Dickerson B, Domoto-Reilly K, Elahi FM, Fields J, Fong JC, Forsberg L, Ghoshal N, Graff-Radford N, Grossman M, Heuer HW, Hsiung …
• Plasma Glial Fibrillary Acidic Protein Levels Differ Along the Spectra of Amyloid Burden and Clinical Disease Stage.
  Journal of Alzheimer's disease : JAD 2020 Asken BM, Elahi FM, La Joie R, Strom A, Staffaroni AM, Lindbergh CA, Apple AC, You M, Weiner-Light S, Brathaban N, Fernandes N, Karydas A, Wang P, Rojas JC, Boxer AL, Miller BL, Rabinovici GD, Kramer …
• Nonlinear Z-score modeling for improved detection of cognitive abnormality.
  Alzheimer's & dementia (Amsterdam, Netherlands) 2019 Kornak J, Fields J, Kremers W, Farmer S, Heuer HW, Forsberg L, Brushaber D, Rindels A, Dodge H, Weintraub S, Besser L, Appleby B, Bordelon Y, Bove J, Brannelly P, Caso C, Coppola G, Dever R, Dheel C, …
• State and trait characteristics of anterior insula time-varying functional connectivity.
  NeuroImage 2019 Pasquini L, Toller G, Staffaroni A, Brown JA, Deng J, Lee A, Kurcyus K, Shdo SM, Allen I, Sturm VE, Cobigo Y, Borghesani V, Battistella G, Gorno-Tempini ML, Rankin KP, Kramer J, Rosen HH, Miller BL, …
• Peripheral Innate Immune Activation Correlates With Disease Severity in GRN Haploinsufficiency.
  Frontiers in neurology 2019 Ljubenkov PA, Miller Z, Mumford P, Zhang J, Allen IE, Mitic L, Staffaroni A, Heuer H, Rojas JC, Cobigo Y, Karydas A, Pearlman R, Miller B, Kramer JH, McGrath MS, Rosen HJ, Boxer AL
• C-24 Longitudinal Trajectories of Working Memory Performance in Typically Aging Older Adults.
  Archives of Clinical Neuropsychology 2019 M Gonzalez Catalan, C Lindbergh, A Staffaroni, S Walters, K Casaletto, N Walker, J Kramer
• Association of Blood and Cerebrospinal Fluid Tau Level and Other Biomarkers With Survival Time in Sporadic Creutzfeldt-Jakob Disease.
  JAMA neurology 2019 Staffaroni AM, Kramer AO, Casey M, Kang H, Rojas JC, Orrú CD, Caughey B, Allen IE, Kramer JH, Rosen HJ, Blennow K, Zetterberg H, Geschwind MD
• Robust normative standards for the California Verbal Learning Test (CVLT) ages 60-89: A tool for early detection of memory impairment.
  The Clinical neuropsychologist 2019 Kramer AO, Casaletto KB, Umlauf A, Staffaroni AM, Fox E, You M, Kramer JH
• STEP COUNT AND PSYCHOLOGICAL HEALTH IN OLDER ADULTS.
  Alzheimer's & Dementia 2019 Sophia A. Weiner-Light, Samantha Walters, Nina Djukic, Michelle You, Devyn Cotter, Marie Altendahl, Fanny Elahi, Adam M. Staffaroni, Cutter A. Lindbergh, Joel H. Kramer, Kaitlin B. Casaletto
• THE MULTIDOMAIN IMPAIRMENT RATING (MIR) SCALE: INITIAL RELIABILITY DATA ON A MULTIDIMENSIONAL SCALE DESIGNED FOR FTLD SPECTRUM DISORDERS.
  Alzheimer's & Dementia 2019 Leah K. Forsberg, Bradley F. Boeve, Adam L. Boxer, Howard J. Rosen, John Kornak, Hilary W. Heuer, Julie A. Fields, Danielle Brushaber, Mary M. Machulda, Virginia Sturm, Adam M. Staffaroni, Peter A. …
• Frontotemporal Dementia.
  The Oxford Handbook of Adult Cognitive Disorders 2019 Andrea G. Alioto, Christie C. Mead, Alicia B. Vanden Bussche Jantz, Adam M. Staffaroni, Joel H. Kramer
• Efficacy of Mindfulness-Based Cognitive Training in Surgery: Additional Analysis of the Mindful Surgeon Pilot Randomized Clinical Trial.
  JAMA network open 2019 Lebares CC, Guvva EV, Olaru M, Sugrue LP, Staffaroni AM, Delucchi KL, Kramer JH, Ascher NL, Harris HW
• Plasma neurofilament light chain predicts disease progression in asymptomatic genetic frontotemporal dementia (P5.1-007).
  Neurology 2019 Julio Rojas -Martinez, Ping Wang, Adam Staffaroni, Yann Cobigo, Amy Wolf, Hilary Heuer, Jamie Fong, Joanne Taylor, Andreas Jeromin, Howard Rosen, Bradley Boeve, Adam Boxer
• Cognitive aging is not created equally: differentiating unique cognitive phenotypes in "normal" adults.
  Neurobiology of aging 2019 Casaletto KB, Elahi FM, Staffaroni AM, Walters S, Contreras WR, Wolf A, Dubal D, Miller B, Yaffe K, Kramer JH
• Primary School Education May Be Sufficient to Moderate a Memory-Hippocampal Relationship.
  Frontiers in aging neuroscience 2018 Resende EPF, Rosen HJ, Chiang K, Staffaroni AM, Allen I, Grinberg LT, Carmona KC, Guimarães HC, Carvalho VA, Barbosa MT, de Souza LC, Caramelli P
• "Liquid Biopsy" of White Matter Hyperintensity in Functionally Normal Elders.
  Frontiers in aging neuroscience 2018 Elahi FM, Casaletto KB, Altendahl M, Staffaroni AM, Fletcher E, Filshtein TJ, Glymour MM, Miller BL, Hinman JD, DeCarli C, Goetzl EJ, Kramer JH
• Cerebrospinal fluid biomarkers predict frontotemporal dementia trajectory.
  Annals of clinical and translational neurology 2018 Ljubenkov PA, Staffaroni AM, Rojas JC, Allen IE, Wang P, Heuer H, Karydas A, Kornak J, Cobigo Y, Seeley WW, Grinberg LT, Spina S, Fagan AM, Jerome G, Knopman D, Boeve BF, Dickerson BC, Kramer J, …
• ENDOTHELIAL-DERIVED EXOSOME BIOMARKERS SUGGEST ACTIVATION OF INNATE IMMUNITY IN SUBCLINICAL CEREBROVASCULAR DISEASE.
  Alzheimer's & Dementia 2018 Fanny Elahi, Marie Altendahl, Teresa J. Filshtein, Kaitlin Casaletto, Adam M. Staffaroni, Wilfredo Rivera Contreras, Anna M. Karydas, Yann Cobigo, Evan Fletcher, Baljeet Singh, Oliver Martinez, Howard…
• PRIMARY SCHOOL EDUCATION CAN BE SUFFICIENT TO MODERATE THE RELATIONSHIP BETWEEN HIPPOCAMPUS VOLUME AND MEMORY PERFORMANCE.
  Alzheimer's & Dementia 2018 Elisa de Paula França Resende, Howard J. Rosen, Kevin Chiang, Isabel Allen, Adam M. Staffaroni, Lea Tenenholz Grinberg, Karoline Carvalho Carmona, Henrique Cerqueira Guimaraes, Viviane Amaral Carvalho…
• THE NIH-EXAMINER IS SENSITIVE TO COGNITIVE CHANGES IN ASYMPTOMATIC AND MILDLY SYMPTOMATIC FAMILIAL FRONTOTEMPORAL DEMENTIA.
  Alzheimer's & Dementia 2018 Adam M. Staffaroni, Lynn Bajorek, Peter Ljubenkov, Kaitlin Casaletto, Fanny Elahi, Katya Rascovsky, Bradley F. Boeve, Adam L. Boxer, Jessica Bove, Danielle Brushaber, Giovanni Coppola, Christina Dheel…
• Perceived Stress is Associated with Accelerated Monocyte/Macrophage Aging Trajectories in Clinically Normal Adults.
  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2018 Casaletto KB, Staffaroni AM, Elahi F, Fox E, Crittenden PA, You M, Neuhaus J, Glymour M, Bettcher BM, Yaffe K, Kramer JH
• A comparison of biofluid cytokine markers across platform technologies: Correspondence or divergence?
  Cytokine 2018 Casaletto KB, Elahi FM, Fitch R, Walters S, Fox E, Staffaroni AM, Bettcher BM, Zetterberg H, Karydas A, Rojas JC, Boxer AL, Kramer JH
• Telomere attrition is associated with declines in medial temporal lobe volume and white matter microstructure in functionally independent older adults.
  Neurobiology of aging 2018 Staffaroni AM, Tosun D, Lin J, Elahi FM, Casaletto KB, Wynn MJ, Patel N, Neuhaus J, Walters SM, Epel ES, Blackburn EH, Kramer JH
• Biomarkers of Cerebral Small Vessel Endotheliopathy (S48.005).
  Neurology 2018 Fanny Elahi, Marie Altendahl, Adam Staffaroni, Kaitlin Casaletto, Pauline Maillard, John Neuhaus, Jason Hinman, Charles DeCarli, Edward Goetzl, Joel Kramer
• Clinical Dementia Rating Score 0.5 Predicts Clinical Decline in Familial Frontotemporal Dementia (S48.007).
  Neurology 2018 Salvatore Spina, Adam Staffaroni, Luke Bonham, Nicholas Olney, Suneth Attygalle, Yann Cobigo, Kevin Chang, Richard Binney, Jennifer Yokoyama, John Kornak, Adam Boxer, Bruce Miller, Suzee Lee, Bradley …
• Multimodal MRI Staging Improves Clinico-Imaging Correlations in sJCD. (P3.177).
  Neurology 2018 Simone Sacco, Eduardo Caverzasi, Matteo Paoletti, Adam Staffaroni, Isabel Allen, Gabriel Marx, Joel Kramer, Stefano Bastianello, Roland Henry, Howard Rosen, Michael Geschwind
• Peripheral Innate Immune Activation Correlates with Disease Severity in GRN Mutation Carriers (P4.178).
  Neurology 2018 Peter Ljubenkov, Paige Mumford, Michael McGrath, Isabel Elaine Allen, Zachary Miller, Laura Mitic, Anna Karydas, Hilary Heuer, Julio Rojas-Martinez, Ping Wang, Jane Zhang, Adam Staffaroni, Yann Cobigo…
• Plasma Biomarkers in Early Neurodegenerative Disease Stages (P3.027).
  Neurology 2018 Fanny Elahi, Kaitlin Casaletto, Adam Staffaroni, John Neuhaus, Yann Cobigo, Emily Fox, Samantha Walters, Marie Altendahl, Ryan Fitch, Anna Karydas, Jason Hinman, Charles DeCarli, Adam Boxer, Gil …
• Four- and five-factor models of the WAIS-IV in a clinical sample: Variations in indicator configuration and factor correlational structure.
  Psychological assessment 2018 Staffaroni AM, Eng ME, Moses JA, Zeiner HK, Wickham RE
• Neuroimaging in Dementia.
  Seminars in neurology 2017 Staffaroni AM, Elahi FM, McDermott D, Marton K, Karageorgiou E, Sacco S, Paoletti M, Caverzasi E, Hess CP, Rosen HJ, Geschwind MD
• Longitudinal white matter change in frontotemporal dementia subtypes and sporadic late onset Alzheimer's disease.
  NeuroImage. Clinical 2017 Elahi FM, Marx G, Cobigo Y, Staffaroni AM, Kornak J, Tosun D, Boxer AL, Kramer JH, Miller BL, Rosen HJ
• Data-driven regions of interest for longitudinal change in three variants of frontotemporal lobar degeneration.
  Brain and behavior 2017 Binney RJ, Pankov A, Marx G, He X, McKenna F, Staffaroni AM, Kornak J, Attygalle S, Boxer AL, Schuff N, Gorno-Tempini ML, Weiner MW, Kramer JH, Miller BL, Rosen HJ
• The functional neuroanatomy of verbal memory in Alzheimer's disease: [18F]-Fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) correlates of recency and recognition memory.
  Journal of clinical and experimental neuropsychology 2016 Staffaroni AM, Melrose RJ, Leskin LP, Riskin-Jones H, Harwood D, Mandelkern M, Sultzer DL
• Progression of Brain Atrophy and Cognitive Impairment in Hereditary Frontotemporal Lobar Degeneration (P6.247).
  Neurology 2016 Salvatore Spina, Howie Rosen, Adam Staffaroni, Luke Bonham, Suneth Attygalle, John Kornak, Joel Kramer, Bruce Miller, Suzee Lee
• Data-driven regions of interest for longitudinal change in frontotemporal lobar degeneration.
  NeuroImage. Clinical 2015 Pankov A, Binney RJ, Staffaroni AM, Kornak J, Attygalle S, Schuff N, Weiner MW, Kramer JH, Dickerson BC, Miller BL, Rosen HJ
• CapMan: independent investigation of capacity and manipulation with a new working memory paradigm.
  Brain imaging and behavior 2014 Dobryakova E, Staffaroni A, DeLuca J, Sumowski JF, Chiaravalloti N, Wylie GR